The dynamics of the incidence of breast cancer in the Moscow region (2011–2018)

Introduction. Breast cancer is a serious medical and social challenge and the statistics around the world look daunting.Relevance. The incidence of breast cancer is increasing in most countries and this may be due to a number of reasons. First of all, it should be noted the improvement of diagnostic methods, in particular, mass mammographic screening, which allows detecting neoplasms at early stages, before the onset of clinical symptoms. As for mortality rates, in recent years, world statistics show a downward trend in rates.Goal. To analyze the incidence and mortality rates of breast cancer (BC) in the Moscow Region (MO) for the period from 2011 to 2018. The study of indicators in one of the regions of Russia – MO – is of great importance for determining and predicting the true needs of the population in specialized medical care.The purpose of the study was to analyze the incidence of breast cancer (breast cancer) in the Moscow Region (MO) for a period of time from 2011 to 2018.Materials and methods. Some data of the territorial cancer registry of the Ministry of Defense of the Russian Federation on the diagnosis and treatment of patients with breast cancer were used, which will make it possible to determine the needs of this cohort of patients in specialized care.Results. From 2011 to 2018, 26755 new cases of breast cancer were diagnosed in the Moscow Region. The analysis of the comparative stratification in breast cancer in the medical district made it possible to obtain statistically significant differences indicating an increase in the incidence in the period from 2015–2018 in comparison with the period of 2011–2014. The presented data also indicate a trend towards a decrease in the one-year mortality rate over 8 years: from 6.33% in 2011 to 5.32% in 2018. For the period from 2011 to 2018 (8 years) there is an increase in the number of patients with breast cancer who have been in the medical center under dispensary supervision for 5 years or more.Conclusions. Analysis of the data obtained on the indicators of morbidity and mortality from malignant neoplasms is of great importance for determining the needs of the population in specialized medical care.

Download Full-text

The dynamics of the incidence of breast cancer in the Moscow region (2011–2018)

Clinical review for general practice ◽

10.47407/kr2021.2.1.00032 ◽

2021 ◽

Vol 2 (1) ◽

pp. 50-56

Author(s):

Ekaterina V. Markarova ◽

◽

Lali M. Kogoniya ◽

Vladimir L. Astashov ◽

◽

...

Keyword(s):

Breast Cancer ◽

Medical Care ◽

Moscow Region ◽

Morbidity And Mortality ◽

Malignant Neoplasms ◽

Region Analysis ◽

Cancer Register ◽

Cancer Breast ◽

Observation Period

Aim. The purpose of the study was to analyze the incidence of breast cancer (breast cancer) in the Moscow Region (MO) for a period of time from 2015 to 2018. Materials and methods. The data of the territorial Cancer Register of the MO are used. Results. During the observation period of 4 years, 14 024 new cases of breast cancer were diagnosed on the territory of the Moscow Region. Analysis of data on morbidity and mortality from malignant neoplasms is of great importance for determining the needs of the population in specialized medical care.

Download Full-text

About the prognosis of breast reconstruction quantity after mastectomy in cancer cases

Vestnik of Russian military medical Academy ◽

10.17816/brmma25984 ◽

2020 ◽

Vol 22 (1) ◽

pp. 146-151

Author(s):

N S Romanenkov ◽

K N Movchan ◽

V V Hizha ◽

A V Zharkov ◽

U M Morozov ◽

...

Keyword(s):

Breast Cancer ◽

Medical Care ◽

Survival Rates ◽

Epidemiological Data ◽

Mammary Glands ◽

High Tech ◽

Malignant Neoplasms ◽

Number Of Patients ◽

Working Age ◽

Active Detection

The 5-year survival rates for women with breast cancer are steadily increasing. The number of cases of mastectomy for breast cancer is not reduced annually. In this regard, the analysis of epidemiological data on the observations of breast cancer in women in Russia seems to be an urgent activity in terms of predicting measures to optimize the volume of the recovery component of providing medical care to patients who have undergone mastectomy. It was established that in2017 in St. Petersburg the incidence rate of breast cancer reached 60,1100/. The parameter of the prevalence of malignant0000neoplasms of the mammary glands for the analyzed period exceeds the similar all-Russian by 19,3%. The frequency of casesof active detection of breast cancer in 2011-2018. increased 7,2 times. In the same period, the number of working-age urbanwomen diagnosed with breast cancer increased by 16,6%. The proportion of cases of verification of breast cancer of the I - IIstage of the tumor process in 2011-2018 increased by 1,2 times, reaching 72,2% in 2018. From 2011 to 2018, the growth of5-year survival of patients with breast cancer in St. Petersburg reached 4,9%, amounting to 63,4 in 2018% The parameterof annual mortality in breast cancer in 2011-2018 decreased by 30,6%. The performance indicators of the St. PetersburgOncology Service for the treatment of patients with breast cancer are comparable with similar parameters in Moscow clinicsand medical organizations in Russia as a whole. The increase in potential needs for prosthetics of the mammary glands dueto the increase in the number of patients with cancer who underwent mastectomy, in the future will necessitate the expansionof the high-tech types of medical care provided to patients suffering from malignant neoplasms of the mammary glands.

Download Full-text

The working of the urology department during the COVID-19 epidemic

Urologicheskie vedomosti ◽

10.17816/uroved52792 ◽

2020 ◽

Vol 10 (4) ◽

pp. 301-307

Author(s):

Ekaterina V. Kul’chavenya ◽

Denis P. Kholtobin ◽

Alexander I. Neymark

Keyword(s):

Medical Center ◽

Total Duration ◽

World Health ◽

Medical Attention ◽

Malignant Neoplasms ◽

City Hospital ◽

Strict Adherence ◽

Number Of Patients ◽

Coronavirus Infection ◽

Research Institute

Introduction. In March 2020, the World Health Organization declared the outbreak of the novel coronavirus infection (COVID-19) a pandemic. The pandemic also significantly affected all academic, scientific and educational activities. Material and methods. We compared the work of the urological departments of the private (Medical Center Avicenna, Novosibisk) and municipal (City Clinical Hospital No. 11, Barnaul) clinics, as well as the urogenital department of the Novosibirsk Research Institute of Tuberculosis of the Ministry of Healthcare of Russia for 6 months of calm 2019, and the first half of 2020, which coincided with the start of the COVID-19 coronavirus pandemic. Results. In March 2020, the urogenital department of the Novosibirsk Research Institute of Tuberculosis of the Ministry of Healthcare of Russia was redesigned into an observational one. In the first half of 2020, patients with malignant neoplasms, varicocele, chronic pyelonephritis, hydronephrosis, dropsy of the testicular membranes and with phimosis/paraphimosis were admitted to the urology department of the City Hospital No. 11 in Barnaul in the first half of 2020. On the contrary, statistically significant in 2020 the number of patients admitted for kidney abscess and acute prostatitis prevailed. It can be assumed that, due to the tense epidemic situation, patients postponed seeking medical attention until their condition required emergency intervention. In the Medical Center Avicenna (Novosibirsk) in the first half of 2020 the number of visits to the pediatric urologist significantly decreased, the inpatient and average bed-day decreased. On the contrary the total duration of the patients' stay in the day hospital has significantly increased, which is logically explained by the epidemic situation; there was a statistically significant decrease in the number of most operations and outpatient procedures. Conclusion. The new coronavirus infection has affected all spheres of human life, to a maximum extent on medicine. In the first six months, no unified approaches to the management of urological patients in epidemic conditions were developed; clinics worked according to internal standards. Our analysis showed that strict adherence to sanitary and hygienic standards and the implementation of anti-epidemic measures allows us to provide urological care to patients in full-even in such unfavorable conditions.

Download Full-text

Analysis of statistical indicators of the population of Saint Petersburg with malignant neoplasms of pancreas

Vestnik of Russian military medical Academy ◽

10.17816/brmma60343 ◽

2021 ◽

Vol 23 (2) ◽

pp. 155-164

Author(s):

Vladislav E. Moiseenko ◽

Alexander V. Pavlovsky ◽

Dmitry A. Granov ◽

Larisa V. Kochorova ◽

Inna V. Dodonova ◽

...

Keyword(s):

Pancreatic Cancer ◽

Stage Iv ◽

Malignant Neoplasms ◽

Number Of Patients ◽

Incidence And Mortality ◽

Significant Downward Trend ◽

Accumulation Index ◽

One Year ◽

The One ◽

Statistical Indicators

Morbidity and mortality from pancreatic cancer is an urgent medical and social problem. Evaluation of statistical indicators in dynamics makes it possible to identify organizational and clinical problems in providing care to patients with malignant neoplasms of the pancreas. Medical and statistical indicators of incidence of malignant pancreatic neoplasms in St. Petersburg residents are evaluated. The assessment of medical and statistical indicators of the incidence of malignant neoplasms of the pancreas in residents of St. Petersburg. Statistical data were studied for the period from 2014 to 2019. The increase in the "rough" indicator of primary morbidity changed from 417.99 per 100 thousand population in 2014 to 505.6 in 2019. In the structure of primary cancer incidence, the indicator of active detection of pancreatic cancer glands in 2014 amounted to 3.6%, in 2019 3.8%. The proportion of patients with diagnoses confirmed morphologically increased from 48.9% to 61.4%. The proportion of patients with newly diagnosed stage IV of the disease changed from 39.5% in 2014 to 51.4% in 2019, and in patients with stage III in 2019 it was 33.3% (a decrease in comparison with 2014 15.3%). In 2019, the disease was diagnosed at stage II in 15.2% of patients. The proportion of patients with stage I in 2019 was 6.6%, this indicator in 2014 was registered at the level of 19.2%. From 2014 to 2019, the one-year mortality rate did not change and amounted to 67.9 and 67.4%, respectively (the decrease was 0.7%). Over the past 5 years, there has been no significant downward trend in the "rough" incidence and mortality rates from pancreatic cancer. However, in the dynamics, there was an increase in the number of patients registered for 5 or more years, and an increase in the accumulation index of the contingent of patients with pancreatic cancer.

Download Full-text

A Review of the Potential Benefits of Increasing Vitamin D Status in Mongolian Adults through Food Fortification and Vitamin D Supplementation

Nutrients ◽

10.3390/nu11102452 ◽

2019 ◽

Vol 11 (10) ◽

pp. 2452 ◽

Cited By ~ 2

Author(s):

William B. Grant ◽

Barbara J. Boucher

Keyword(s):

Vitamin D ◽

Birth Outcomes ◽

Mortality Rates ◽

Malignant Neoplasms ◽

Supplement Use ◽

Incidence And Mortality ◽

Pregnancy And Birth Outcomes ◽

Adverse Pregnancy ◽

Tract Infections ◽

Pregnancy And Birth

Serum 25-hydroxyvitamin D (25(OH)D) concentrations are low in Mongolia, averaging 22 ng/mL in summer and only 8 ng/mL in winter. Mongolians have high incidence and/or prevalence of several diseases linked to low 25(OH)D concentrations, including ischemic heart disease, malignant neoplasms, cirrhosis of the liver, ischemic stroke, lower respiratory tract infections, preterm birth complications, and diabetes mellitus. Fortifying regularly consumed foods such as flour, milk, and edible oils with vitamin D3 could raise 25(OH)D concentrations by about 10 ng/mL. However, to achieve 25(OH)D concentrations of 30–40 ng/mL in adults, vitamin D intakes of 1000 to 4000 IU/day would be required, making personal supplement use necessary. On the basis of prospective observational studies and clinical trials of disease incidence or known mortality rates and adverse pregnancy and birth outcomes, raising mean serum 25(OH)D concentrations to 40 ng/mL would likely reduce incidence and mortality rates for those and other diseases, reduce the rate of adverse pregnancy and birth outcomes, and increase mean life expectancy by one year or more.

Download Full-text

Breast Cancer Research in the Caribbean: Analysis of Reports From 1975 to 2017

Journal of Global Oncology ◽

10.1200/jgo.18.00044 ◽

2018 ◽

pp. 1-21 ◽

Cited By ~ 2

Author(s):

Camille Ragin ◽

Rishika Banydeen ◽

Christine Zhang ◽

Athena Ben ◽

Victoria Calabrese ◽

...

Keyword(s):

Breast Cancer ◽

Breast Cancer Incidence ◽

Mortality Rates ◽

The Body ◽

Cancer Registration ◽

Future Research ◽

Caribbean Women ◽

Incidence And Mortality ◽

High Incidence ◽

The Caribbean

Purpose Breast cancer is among the leading causes of death resulting from cancer in Caribbean women. Studies examining exogenous and genetically predetermined endogenous risk factors are critical to define breast cancer susceptibility in Caribbean women. The purpose of this systematic review is to assess the existing scientific literature in the last 42 years (1975 to 2017) to describe the body of research generated for the population of this region and determine future research directions. Methods We selected published research articles using a combination of definite keyword searches in PubMed. Only articles presenting the Caribbean population as the focus of their research objectives were included in this analysis. Results Studies on breast cancer in the Caribbean are limited. A majority of publications on Caribbean populations were descriptive, focusing on cancer trends and clinicopathologic factors. High incidence and mortality rates for breast cancer are reported for the region, and there seem to be some differences between countries in the frequency of cases according to age at presentation. A limited number of epidemiologic, behavioral, and genetic and molecular studies were conducted in more recent years. Conclusion A regional strategy for cancer registration is needed for the Caribbean to address possible underestimates of breast cancer incidence. Furthermore, behavioral, molecular, genetic, and epidemiologic investigations of breast cancer are critical to address the concerns related to currently described high incidence and mortality rates in the Caribbean.

Download Full-text

International Variation in Female Breast Cancer Incidence and Mortality Rates

Cancer Epidemiology Biomarkers & Prevention ◽

10.1158/1055-9965.epi-15-0535 ◽

2015 ◽

Vol 24 (10) ◽

pp. 1495-1506 ◽

Cited By ~ 267

Author(s):

Carol E. DeSantis ◽

Freddie Bray ◽

Jacques Ferlay ◽

Joannie Lortet-Tieulent ◽

Benjamin O. Anderson ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Incidence ◽

Breast Cancer Incidence ◽

Mortality Rates ◽

Female Breast Cancer ◽

International Variation ◽

Female Breast ◽

Incidence And Mortality

Download Full-text

Mapping of Female Breast Cancer Incidence and Mortality Rates to Socioeconomic Factors: From Univariate Analysis to Path Diagram Analysis

10.21203/rs.3.rs-67659/v1 ◽

2020 ◽

Author(s):

Qiongle Peng ◽

Xiaoling Ren ◽

Bing Cui ◽

Henggui Cui

Keyword(s):

Breast Cancer ◽

Socioeconomic Factors ◽

Univariate Analysis ◽

Breast Cancer Incidence ◽

Mortality Rates ◽

Female Breast Cancer ◽

Economic Wealth ◽

Female Breast ◽

Path Coefficients ◽

Incidence And Mortality

Abstract PURPOSE: Breast cancer is the leading cause of death in females around the world. Its occurrence and development has been linked to genetic factors, living habits and health conditions, but also by socioeconomic factors. Comparisons of incidence and mortality rates of female breast cancer are useful approaches to define cancer-related socioeconomic disparities. METHODS: International Agency for Research on Cancer's CANCERMondial clearinghouse was used to determine the incidence and mortality rates of female breast cancer data from several developed countries for 1980–2012. We subsequently investigated the effects of socioeconomic factors on breast cancer incidence and mortality rates by regression methods from univariate analysis to path diagram analysis. RESULTS: The relationship between socioeconomic factors and the occurrence and development of breast cancer did not follow a monotonic function. We found a positive, significant association of national public wealth (GDP) on the incidence and mortality of breast cancer. The path coefficients in the structuralequations model are -0.51 and -0.39, respectively. In addition to the significant relationship between individual physical and psychological characteristics, social pressure, such as unemployment rate (UR) has a significant impact on the incidence and mortality of breast cancer. The path coefficients in the structural equations model are all 0.2. The path coefficients of individual economic wealth to the incidence rate and mortality rate of breast cancer is 0.18 and 0.27, respectively. CONCLUSIONS: A significant statistical relationship between the socioeconomic development and the crude rates of female breast cancer was shown in this study. The incidence and mortality rates of breast cancer can be regulated effectively by a moderate increase in GDP, and clearly was affected by the individual’s economic wealth (GDPPC). In addition, the influence of social pressure (e.g., unemployment rate) on the incidence and mortality of breast cancer was not typical monotonous. The survival rate of breast cancer determined by the ratio of mortality rate to incidence rate also showed a similar pattern with socioeconomic factors.

Download Full-text

CANCER OF TRACHEA, BRONCHI AND LUNG IN THE FAR EASTERN FEDERAL DISTRICT

Bulletin physiology and pathology of respiration ◽

10.12737/article_5c89a5ae3f5443.13929986 ◽

2019 ◽

Vol 1 (71) ◽

pp. 71-79

Author(s):

Виктор Гордиенко ◽

Viktor Gordienko ◽

А. Вахненко ◽

A. Vahnenko ◽

Д. Екония ◽

...

Keyword(s):

Medical Care ◽

Cancer Patients ◽

Federal District ◽

Morbidity And Mortality ◽

Malignant Neoplasms ◽

Oncology Patients ◽

Female Population ◽

Annual Increase ◽

Number Of Patients ◽

Far Eastern

The first two decades of the XXI century in the Far Eastern Federal District continue to be characterized by a constantly decreasing level of the population living on its territory with an annual increase in the number of patients with cancer pathology, which makes a negative contribution to the already negative demographic situation in the region. The purpose of this study was to make a scientific assessment of the main morbidity and mortality rates of the population from malignant tumors of the trachea, bronchi and lung in the Far Eastern Federal District over the past ten years (2008-2017). In the course of the work, morbidity and mortality indicators, reporting forms of statistical records of cancer patients and regulatory documents of higher organizations, information on ten-year observations of the dynamics of changes in the numerical values of indicators of the studied pathology were used. The main indicators of medical care for oncology patients in the Far Eastern Federal District are shown, and it was found out that 3180 new cases of tracheal, bronchial and lung malignant neoplasms were registered in 2017, which is 30.9% more than ten years ago (in 2008 there were 2429 cases). The maximum number of cases was in the age group of 50-69 years. The number of patients with stages I-II (29.4%) of the cancer process increased slightly whereas the number of patients with advanced forms of the disease increased significantly (41.5%). The percentage of patients identified during routine check-ups was 28.0% (in 2008 it was 15.8%). Mortality in the first year from the time of diagnosis was reduced to 49.2% (in 2008 – 55.0%) remaining, at the same time, at very high numbers, which makes it impossible to characterize medical care for oncology patients as adequate for the time required. In the structure of total mortality, trachea, bronchus and lung tumors (20.7%) take the first place significantly exceeding the Russian level (17.3%). There was designated the quality of the service’s activity according to the confidence index of accounting for this category of patients, which in 2017 did not fall below 0.6 in any of the territories forming the Far Eastern Federal District. A great deal of work of primary health care institutions responsible for identifying malignant neoplasms in the initial stages of the process, unfortunately, has not led to the desired reduction in morbidity and mortality in the Far Eastern Federal District in the last decade. On the contrary, the level of intensive indicators of medical care for cancer patients in the region remains high, with an annual increase in mortality and the number of cases, especially among the female population

Download Full-text

Mapping of female breast cancer incidence and mortality rates to socioeconomic factors cohort: Path diagram analysis

10.21203/rs.3.rs-67659/v2 ◽

2020 ◽

Author(s):

Qiongle Peng ◽

Xiaoling Ren ◽

Bing Cui ◽

Henggui Cui

Keyword(s):

Breast Cancer ◽

Socioeconomic Factors ◽

Unemployment Rate ◽

Mortality Rates ◽

Female Breast Cancer ◽

Structural Equations ◽

Economic Wealth ◽

Female Breast ◽

Path Coefficients ◽

Incidence And Mortality

Abstract BACKGROUND: Breast cancer is the leading cause of death in females around the world. Its occurrence and development has been linked to genetic factors, living habits and health conditions, and socioeconomic factors. Comparisons of incidence and mortality rates of female breast cancer are useful approaches to define cancer-related socioeconomic disparities. METHODS: This was a retrospective observational cohort study on breast cancer of females in several developed countries between 1980 and 2012. The path diagram analysis for five factors, i.e. years, population, gross domestic product, gross domestic product per capita, and unemployment rate, were conducted using Excel database function, and the effects on breast cancer incidence and mortality rates were analyzed. International Agency for Research on Cancer's CANCERMondial clearinghouse was used to determine the incidence and mortality rates of female breast cancer data from several developed countries for 1980–2012. RESULTS: The relationship between socioeconomic factors and the occurrence and development of breast cancer did not follow a monotonic function. We found a positive, significant association of national public wealth on the incidence and mortality of breast cancer. The path coefficients in the structural equations model are -0.51 and -0.39, respectively. In addition to the significant relationship between individual physical and psychological characteristics, social pressure, such as unemployment rate has a significant impact on the incidence and mortality of breast cancer. The path coefficients in the structural equations model are all 0.2. The path coefficients of individual economic wealth to the incidence rate and mortality rate of breast cancer is 0.18 and 0.27, respectively. CONCLUSIONS: A significant statistical relationship between the socioeconomic development and the crude rates of female breast cancer was shown in this study. The incidence and mortality rates of breast cancer can be regulated effectively by a moderate increase in national public wealth, and clearly was affected by the individual’s economic wealth. In addition, the influence of social pressure (e.g., unemployment rate) on the incidence and mortality of breast cancer was not typical monotonous. The survival rate of breast cancer determined by the ratio of mortality rate to incidence rate also showed a similar pattern with socioeconomic factors.

Download Full-text