scholarly journals Assessment of vitamin D supply at different age

2021 ◽  
pp. 294-303
Author(s):  
E. I. Kondratyeva ◽  
E. V. Loshkova ◽  
I. N. Zakharova ◽  
Yu. F. Shubina ◽  
T. V. Saprina ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Optimal Level ◽  
Mean Value ◽  
Positive Trend ◽  
Adequate Level ◽  
Severe Deficiency ◽  
Global Nature ◽  
Relationship Of ◽  
The Relationship

Introduction. Carrying out studies on the supply of vitamin D in the Russian population is an important task in order to demonstrate the global nature of the problem of vitamin D deficiency.Objective of  the  study. To conduct a  study of  the  level of  vitamin  D at different age periods and to assess the  relationship of the 25(OH)D supply with the seasons of the year.Materials and methods. The study included 10707 people, 78.8% (n = 2323) women and 21.2% (n = 2266) men, mean age 49.86 ± 21.925 years (Me 56.00).Results. Only 17.1% (n = 1833) of the examined had an adequate level of 25(OH)D, 31.4% (n = 3362) people had an insufficient level of 25 (OH) D, 43.7% (n = 4681) of the examined – a deficiency of 25(OH)D and among 7.8% (n = 831) a severe deficiency of 25(OH)D was revealed. An adequate level of 25(OH)D was found only in the group of children under 3 years of age (mean value 40.55 ng/ml). From 4 to 7 years of age, there is a pronounced 2-fold decrease in the concentration of 25(OH)D in all seasons of the year. A consistently low content of 25(OH)D is observed in the period 8-10 years – 20.91 ng / ml, and in the period 11-18 years – 18.30 ng/ml. The lowest average values of 25(OH)D were found at the age of 11-18 years (18.30 ng/ml) and from 19 to 22 years (19.15 ng/ml), as well as in senile (76 years and above) age (19.05 ng/ml). The lowest median concentration of 25(OH)D is recorded in spring (17.70 ng/ml) and winter (18.80 ng/ml), with a slight positive trend in summer (20.40 ng/ml) and autumn (22.00 ng/ml) season.Conclusions. The optimal level of 25(OH)D was found in every fifth (17.1%) subject, vitamin D deficiency (20.01–30.00 ng/ml) was observed in  every third (3362  people out of  10707  examined, 31.4%), a  moderate calcidiol deficiency is recorded among 4681 people (43.7%), a severe deficiency of 25 (OH) D among the surveyed is 7.8%. 

The relationship of vitamin D deficiency to statin myopathy

2011 ◽  
Vol 215 (1) ◽  
pp. 23-29 ◽  
Author(s):  
Ankur Gupta ◽  
Paul D. Thompson
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Relationship Of ◽  
The Relationship

scholarly journals The Relationship of Vitamin D Deficiency in Type 2 Diabetes Patients: Dhaka, Bangladesh

2021 ◽  
Vol 7 (3) ◽  
pp. 79-84
Author(s):  
  Dr. Amal Krishna Paul ◽  
Dr. Arifa Sultana ◽  
Dr. Ismat Ara Begum
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Relationship Of ◽  
The Relationship ◽  
Diabetes Patients

scholarly journals The Relationship of Vitamin D Deficiency to Health Care Costs in Veterans

2008 ◽  
Vol 173 (12) ◽  
pp. 1214-1218 ◽  
Author(s):  
Alan N. Peiris ◽  
Beth A. Bailey ◽  
Todd Manning
Keyword(s):  
Health Care ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Health Care Costs ◽  
Relationship Of ◽  
The Relationship ◽  
Care Costs

scholarly journals Bronchial asthma and the vitamin D deficiency.

2018 ◽  
Vol 96 (7) ◽  
pp. 590-596 ◽  
Author(s):  
D. S. Fomina ◽  
T. N. Markova ◽  
V. V. Sadovskaya
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Bronchial Asthma ◽  
Inflammatory Diseases ◽  
Positive Effects ◽  
Low Levels ◽  
Tissue Cells ◽  
Relationship Of ◽  
The Relationship

The variety of tissue cells express receptors of vitamin D. The possible causative connection between lack of vitamin D and a number of inflammatory diseases such as bronchial asthma has stimulated interest in the potentially positive effects of vitamin D in the theraputic schemes. Conflicting data was demonstrated by numerous studies concerning the relationship of vitamin D and development of asthma . Most of them stress attention on the lack of studies with targeting population excluding subclasters and phenotypes of bronchial asthma, especially groups associated with low levels of vitamin D obesity, COPD and asthma, atopic patients. The question of prescribing of vitamin D in asthma, in the case of laboratory-proven deficiency or lack of vitamin D can be an option in therapy.

scholarly journals Relationship of the content of vitamin D and melatonin in blood serum and pineal gland calcifications in patients with malignant bone tumors

2021 ◽  
Vol 9 (1) ◽  
pp. 63-69
Author(s):  
Oleg Drobotun ◽  
Mykola Kolotilov ◽  
Mykola Safonov
Keyword(s):  
Vitamin D ◽  
Pineal Gland ◽  
Blood Serum ◽  
Vitamin D Deficiency ◽  
Bone Tumors ◽  
Malignant Tumors ◽  
Lower Extremities ◽  
Malignant Bone Tumors ◽  
Relationship Of ◽  
The Relationship

The aim of the study was to investigate the relationship between the vitamin D content, melatonin and the characteristics of pineal gland calcifications in patients with malignant tumors of the bones of the lower extremities. Vitamin D deficiency and pineal gland calcifications are observed in almost 100 % of patients with malignant tumors of the lower extremities’ bones. The high heterogeneity of calcifications and its dynamics during the treatment of patients may indicate the processes of their litholysis and dissolution.

scholarly journals Relationship of arterial hypertension, metabolic syndrome with vitamin D deficiency in women

2020 ◽  
Vol 43 (4) ◽  
pp. 549-559
Author(s):  
Lyudmila V. Vasilieva ◽  
◽  
Yuliya V. Tatarintseva ◽  
Elena V. Gosteva ◽  
Sergej Y. Popov ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Arterial Hypertension ◽  
Blood Serum ◽  
Vitamin D Deficiency ◽  
Postmenopausal Women ◽  
Blood Pressure Monitoring ◽  
Low Hdl ◽  
Relationship Of ◽  
The Relationship

Objective: To assess the relationship between vitamin D deficiency (VD) and risk factors for metabolic syndrome (MS) in postmenopausal women with arterial hypertension (AH). Materials and methods of research. The study included 46 women aged 45–65 years with amenorrhea > 12 months, having grade 1 hypertension and metabolic syndrome. Anthropometric, laboratory and instrumental data were studied. Biochemical parameters included total cholesterol (OH), HDL, triglycerides, glucose, insulin, and 25-hydroxyvitamin-D [25 (OH)D]. Daily blood pressure monitoring was performed according to the standard protocol. Levels of 25(OH)D in blood serum was classified as-adequate (≥ 30 ng/ml) and insufficient (20–29 ng/ml). Results: Level 25 (OH)D in blood serum was sufficient in 21 women (45.6 %), insufficient – in 25 (54.4 %). Women with insufficient levels of 25 (OH)D had higher levels of cholesterol, triglycerides, insulin, and HOMA-IR. Metabolic syndrome was detected in 64 % (16/25) of women with hypovitaminosis D and in 43 % (9/21) of women with sufficient VD (p < 0.01). The correlation analysis established the relationship of the low level of 25 (OH)D (< 30 ng / ml) with MS (r = 0.68), high triglycerides (r = 0.74) and low HDL (r = 0.71). The average concentration of 25 (OH) D decreased with an increase in the number of MS components (p = 0.016). Conclusions: VD deficiency in postmenopausal women was associated with a higher prevalence of MS. Women with HDL deficiency had a higher risk of MS, hypertriglyceridemia, and low HDL levels compared to those with adequate levels.

scholarly journals Obesity, related diseases and their relationship with vitamin D deficiency in adolescents

2016 ◽  
Vol 33 (4) ◽  
Author(s):  
Jacqueline De Souza Silva
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Meta Analysis ◽  
Vitamin D Supplementation ◽  
Systemic Hypertension ◽  
Controlled Clinical Trials ◽  
Obese Adolescents ◽  
Prevalence Of Obesity ◽  
Relationship Of ◽  
The Relationship

Introduction: The rise in prevalence of obesity has occurred concomitantly to that of vitamin D deficiency (VDD). The aim of this narrative review was to describe the relationship between obesity and such related diseases as VDD in adolescents, in an effort to warn of the risks of this deficiency during this period of growth and development.Methods: We searched the electronic databases PubMed, Medline, Scielo, Science Direct and Lilacs for articles from between 2000 and 2015 on the topics obesity and obesity-related diseases and VDD in adolescents. We included articles written in English, Spanish and Portuguese of the analytical variety (transverse and longitudinal), systematic reviews, meta-analysis and controlled clinical trials on humans, and excluded studies that were done on animals, inconclusive or with undefined methodology.Results: We produced an overview of VDD in obesity, in cardiovascular diseases, in diabetes mellitus, in systemic hypertension, and in dyslipidemia. The prevalence of VDD was considered high in obese adolescents and their relationship with the obesity and related diseases was found in adolescents. These findings forewarn of possible clinical repercussions in the health of the adolescents, foremost because of how essential vitamin D is to growth and development, and for its interaction with obesity and obesity-related diseases.Conclusion: The worldwide rise in the obesity rate alongside the progressively increasing of vitamin D deficiency in adolescents is alarming. This relationship of VDD with the obesity and related diseases was found in adolescents. Vitamin D supplementation is considered promising measure to take with obese adolescents.

Scientific Documentation of the Relationship of Vitamin D Deficiency and the Development of Cancer

2009 ◽  
Vol 28 (2) ◽  
pp. 133-141 ◽  
Author(s):  
Richard Edlich ◽  
Shelley S. Mason ◽  
Margot E. Chase ◽  
Allyson L. Fisher ◽  
K. Dean Gubler ◽  
...  
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Scientific Documentation ◽  
Relationship Of ◽  
The Relationship

Prevalence of Vitamin D Deficiency among Patients Attending a General Otolaryngology Clinic in South Auckland

2009 ◽  
Vol 118 (5) ◽  
pp. 326-328 ◽  
Author(s):  
Jim Bartley ◽  
David Reid ◽  
Randall P. Morton
Keyword(s):  
Vitamin D ◽  
Statistical Analysis ◽  
Vitamin D Deficiency ◽  
Prospective Observational Study ◽  
Vitamin D Status ◽  
Hydroxyvitamin D ◽  
Vitamin D Levels ◽  
25 Hydroxyvitamin D ◽  
Relationship Of ◽  
The Relationship

Objectives: We performed a prospective observational study to estimate the prevalence of vitamin D deficiency in patients attending a general otolaryngology clinic in South Auckland, New Zealand. Methods: From July 21, 2008, to August 7, 2008, all new patients presenting to otolaryngology clinics at which one of the authors (D.R.) was present had their vitamin D status assessed by measurement of their plasma 25-hydroxyvitamin D [25(OH)D] level. Results: Of 48 patients, 2% had 25(OH)D levels of 17.5 nmol/L or less (a level associated with osteomalacia), 58% had 25(OH)D levels of 50 nmol/L or less (a level associated with vitamin D deficiency), and 100% had 25(OH)D levels of 80 nmol/L or less. Conclusions: Most of the patients attending a general otolaryngology clinic in South Auckland are vitamin D–deficient. It is unclear whether low vitamin D levels are associated more directly with otolaryngological disorders or skin type, because the small size of this study and the broad range of conditions seen precluded a meaningful statistical analysis. Further research into the relationship of vitamin D to specific otolaryngological presentations is required.

Abstract 121: Relationship of Vitamin D Level with Cardiovascular Fitness: Does Demography Matter?

2012 ◽  
Vol 5 (suppl_1) ◽  
Author(s):  
Hemang B Panchal ◽  
Saurabh Desai ◽  
Tejaskumar Shah ◽  
Rakeshkumar Patel ◽  
Vijay Ramu
Keyword(s):  
Risk Factors ◽  
Vitamin D ◽  
Young Adults ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Vitamin D Deficiency ◽  
Cardiovascular Fitness ◽  
Normal Vitamin ◽  
Relationship Of ◽  
The Relationship

Background: Recent studies have suggested association of vitamin D with cardiovascular events. The relationship of vitamin D deficiency with cardiovascular fitness level (CVF) has not been studied in current literatures. Demographic variation of this association is also unclear. The primary objective of our study was to assess the relationship of vitamin D level to CVF and evaluate the demographic variation of this association in young adults. The secondary objective of this study was to assess the relationship of vitamin D level with the other cardiovascular risk factors. Methods: We evaluated 5388 adults from National Health and Nutrition Examination Survey 2001-2004. The associations of serum 25-hydroxy vitamin D level with CVF and cardiovascular risk factors such as systolic/diastolic blood pressure (SBP/DBP), low density lipoprotein (LDL), high density lipoprotein (HDL), and glycohemoglobin (HbA1c) levels in young adults aged 20-49 years were evaluated. Adults with vitamin D deficiency (≤30 mg/dL) and normal vitamin D level (>30 mg/dL) were compared. The CVF was assessed with peak oxygen uptake on treadmill test (VO2 max <20 percentile= low CVF, VO2 max ≥60 percentile= high CVF). Chi square analysis and odds ratio were calculated to assess the association of vitamin D deficiency with CVF. Pearson correlation was measured for the secondary analysis of association of vitamin D level with cardiovascular risk factors. The alpha error ≤0.05 was used as a level of significance. Results: Total of 85.4% (n=4603/5388) young adults had vitamin D deficiency. Vitamin D level was positively associated with CVF (p<0.001). In comparison to normal vitamin D level, vitamin D deficiency was significantly associated with low CVF (Odds ratio 2.01, confidence interval 1.64-2.46, p<0.001). In contrast to normal vitamin D level, vitamin D deficiency was significantly associated with low CVF in subgroups of males (p<0.01), females (p<0.01), age group of 20-29 years (p<0.01) and age group of 30-49 years (p<0.01). In contrast to normal vitamin D level, vitamin D deficiency was significantly associated with low CVF only in Caucasians (p=0.001). This association was not significant in Mexican-Hispanics (p=0.35), other Hispanics (p=0.095), African Americans (p=0.061) and other races (p=0.206). In comparison to normal vitamin D level, vitamin D deficiency was significantly associated with low CVF among normal BMI (p<0.001), overweight BMI (p<0.001) and obese adults (p=0.019) but not in underweight BMI adults (p=0.48). Vitamin D level was inversely associated with SBP (p<0.001), and HbA1c (p<0.001) and positively associated with HDL (p<0.001). There was no significant association found between vitamin D level and DBP (p=0.66) or LDL (p=0.79). Conclusions: The results of our study demonstrate that vitamin D deficiency may decrease CVF in Caucasian young adults. Surprisingly it may not affect CVF in other races and underweight adults. Vitamin D deficiency is also associated with increase in cardiovascular risk factors such as low HDL, high SBP and HbA1c. The large population based clinical trials are needed for evaluation of this relationship and long-term consequences on cardiovascular outcomes.

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