The JASMONATE ZIM-DOMAIN family proteins are the important node in jasmonic acid-abscisic acid crosstalk in regulating plant response to drought

2021 ◽  
Vol 22 ◽  
Author(s):  
Aarti Gupta ◽  
Mamta Bhardwaj ◽  
Lam-Son Phan Tran
Keyword(s):  
Abscisic Acid ◽  
Jasmonic Acid ◽  
Biological Processes ◽  
Plant Tolerance ◽  
Adaptive Responses ◽  
Domain Family ◽  
Physiological Processes ◽  
Jaz Proteins ◽  
Ja Signaling ◽  
Insight Into

: Plants modulate the metabolism of phytohormones and their signaling pathways under drought to regulate physiological and adaptive responses. Jasmonic acid (JA) is one of the major classes of phytohormones and has been found to potentially enhance plant tolerance to various abiotic stresses, including drought. The JASMONATE ZIM-DOMAIN (JAZ) proteins are the negative regulators in the JA-signaling pathway. The JAZ protein family is explicit to plants and involved in the regulation of numerous biological processes, including drought-responsive mechanisms. In this review, we synthesize the mechanistic insight into the roles of JAZ proteins in regulation of drought responses by connecting the JA-signaling with abscisic acid-signaling to modulate drought-responsive physiological processes.

scholarly journals Jasmonic Acid Signaling Pathway in Plants

2019 ◽  
Vol 20 (10) ◽  
pp. 2479 ◽  
Author(s):  
Jingjun Ruan ◽  
Yuexia Zhou ◽  
Meiliang Zhou ◽  
Jun Yan ◽  
Muhammad Khurshid ◽  
...  
Keyword(s):  
Jasmonic Acid ◽  
Plant Responses ◽  
Biological Processes ◽  
Biotic And Abiotic Stresses ◽  
Signal Perception ◽  
Physiological Processes ◽  
Jasmonic Acid Signaling ◽  
Ja Signaling ◽  
Local Transmission ◽  
Signal Receptors

Jasmonic acid (JA) and its precursors and dervatives, referred as jasmonates (JAs) are important molecules in the regulation of many physiological processes in plant growth and development, and especially the mediation of plant responses to biotic and abiotic stresses. JAs biosynthesis, perception, transport, signal transduction and action have been extensively investigated. In this review, we will discuss the initiation of JA signaling with a focus on environmental signal perception and transduction, JA biosynthesis and metabolism, transport of signaling molecules (local transmission, vascular bundle transmission, and airborne transportation), and biological function (JA signal receptors, regulated transcription factors, and biological processes involved).

scholarly journals Circadian Network Interactions with Jasmonate Signaling and Defense

Plants ◽  
2019 ◽  
Vol 8 (8) ◽  
pp. 252 ◽  
Author(s):  
Bryan Thines ◽  
Emily V. Parlan ◽  
Elena C. Fulton
Keyword(s):  
Transcription Factor ◽  
Jasmonic Acid ◽  
Circadian Clock ◽  
Fungal Pathogens ◽  
Future Research ◽  
Biotic Stresses ◽  
Clock Proteins ◽  
Jaz Proteins ◽  
Multiple Levels ◽  
Ja Signaling

Plants experience specific stresses at particular, but predictable, times of the day. The circadian clock is a molecular oscillator that increases plant survival by timing internal processes to optimally match these environmental challenges. Clock regulation of jasmonic acid (JA) action is important for effective defenses against fungal pathogens and generalist herbivores in multiple plant species. Endogenous JA levels are rhythmic and under clock control with peak JA abundance during the day, a time when plants are more likely to experience certain types of biotic stresses. The expression of many JA biosynthesis, signaling, and response genes is transcriptionally controlled by the clock and timed through direct connections with core clock proteins. For example, the promoter of Arabidopsis transcription factor MYC2, a master regulator for JA signaling, is directly bound by the clock evening complex (EC) to negatively affect JA processes, including leaf senescence, at the end of the day. Also, tobacco ZEITLUPE, a circadian photoreceptor, binds directly to JAZ proteins and stimulates their degradation with resulting effects on JA root-based defenses. Collectively, a model where JA processes are embedded within the circadian network at multiple levels is emerging, and these connections to the circadian network suggest multiple avenues for future research.

scholarly journals Insight into abscisic acid perception and signaling to increase plant tolerance to abiotic stress

2021 ◽  
Vol 16 (1) ◽  
pp. 222-237
Author(s):  
Abdul Rehman ◽  
Muhammad Tehseen Azhar ◽  
Lori Hinze ◽  
Abdul Qayyum ◽  
Hongge Li ◽  
...  
Keyword(s):  
Abscisic Acid ◽  
Abiotic Stress ◽  
Plant Tolerance ◽  
Insight Into

scholarly journals Wittgenstein on language and nature

2012 ◽  
Vol 23 (1) ◽  
pp. 86-101
Author(s):  
Michal Sladecek
Keyword(s):  
Life Form ◽  
Traditional Approach ◽  
Biological Processes ◽  
Human Relations ◽  
Natural Properties ◽  
Natural Processes ◽  
Physiological Processes ◽  
Intellectual Abilities ◽  
Specific Manner ◽  
Insight Into

The text begins with the analysis of two terms regarding life crucial to both Wittgenstein's early and late philosophy. These are life form and nature, specifically, human nature. Wittgenstein treats both concepts in a very specific manner, different from the traditional approach of philosophy. He also criticized philosophical attempts to attribute special characteristics to human intellectual abilities which would separate them from natural processes. A particular 'spiritual' status of epistemic and other rational powers disappears when there is an insight into their dependence on discursive practices and specific forms of life on which these powers are based. Concepts such as certainty, knowledge, or explanations do not rest on a rational foundation, that is, they do not refer to processes with particular un-natural properties. Nor can they be reduced to neuro-physiological processes, either. Instead, it is a specific grammar of their usage that makes them different from other concepts describing physical or biological processes. In that sense, Wittgenstein develops a non-reductionist version of naturalism which preserves the diversity of human relations in the world.

scholarly journals Electrical Signals, Plant Tolerance to Actions of Stressors, and Programmed Cell Death: Is Interaction Possible?

Plants ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 1704
Author(s):  
Ekaterina Sukhova ◽  
Vladimir Sukhov
Keyword(s):  
Cell Death ◽  
Programmed Cell Death ◽  
Molecular Structures ◽  
Plant Tolerance ◽  
Adaptive Responses ◽  
Long Distance ◽  
Electrical Signals ◽  
Physiological Processes ◽  
Stress Signals ◽  
Phytohormone Synthesis

In environmental conditions, plants are affected by abiotic and biotic stressors which can be heterogenous. This means that the systemic plant adaptive responses on their actions require long-distance stress signals including electrical signals (ESs). ESs are based on transient changes in the activities of ion channels and H+-ATP-ase in the plasma membrane. They influence numerous physiological processes, including gene expression, phytohormone synthesis, photosynthesis, respiration, phloem mass flow, ATP content, and many others. It is considered that these changes increase plant tolerance to the action of stressors; the effect can be related to stimulation of damages of specific molecular structures. In this review, we hypothesize that programmed cell death (PCD) in plant cells can be interconnected with ESs. There are the following points supporting this hypothesis. (i) Propagation of ESs can be related to ROS waves; these waves are a probable mechanism of PCD initiation. (ii) ESs induce the inactivation of photosynthetic dark reactions and activation of respiration. Both responses can also produce ROS and, probably, induce PCD. (iii) ESs stimulate the synthesis of stress phytohormones (e.g., jasmonic acid, salicylic acid, and ethylene) which are known to contribute to the induction of PCD. (iv) Generation of ESs accompanies K+ efflux from the cytoplasm that is also a mechanism of induction of PCD. Our review argues for the possibility of PCD induction by electrical signals and shows some directions of future investigations in the field.

An Insight into Oligopeptide Transporter 3 (OPT3) family proteins

2020 ◽  
Vol 27 ◽  
Author(s):  
Fırat Kurt
Keyword(s):  
Stress Responses ◽  
Chelating Agent ◽  
Biological Processes ◽  
Biotic And Abiotic Stress ◽  
Oligopeptide Transporter ◽  
Binding Residues ◽  
Fe Homeostasis ◽  
Proteins Interactions ◽  
Insight Into ◽  
Selection Of

: Oligopeptide transporter 3 (OPT3) proteins are one of the subsets of OPT clade, yet little is known about these transporters. Therefore, homolog OPT3 proteins in several plant species were investigated and characterized using bioinformatical tools. Motif and co-expression analyses showed that OPT3 proteins may be involved in both biotic and abiotic stress responses as well as growth and developmental processes. AtOPT3 usually seemed to take part in Fe homeostasis whereas ZmOPT3 putatively interacted with proteins involved in various biological processes from plant defense system to stress responses. Glutathione (GSH), as a putative alternative chelating agent, was used in the AtOPT3 and ZmOPT3 docking analyses to identify their putative binding residues. The information given in this study will contribute to the understanding of OPT3 proteins’ interactions in various pathways and to the selection of potential ligands for OPT3s.

scholarly journals OsJAZ11 regulates phosphate starvation responses in rice

Planta ◽  
2021 ◽  
Vol 254 (1) ◽  
Author(s):  
Bipin K. Pandey ◽  
Lokesh Verma ◽  
Ankita Prusty ◽  
Ajit Pal Singh ◽  
Malcolm J. Bennett ◽  
...  
Keyword(s):  
Jasmonic Acid ◽  
Root Length ◽  
Root Elongation ◽  
Terminal Region ◽  
Physical Interaction ◽  
Plant Signaling ◽  
Functional Connections ◽  
Growth Inhibitory ◽  
Expression Studies ◽  
Ja Signaling

Abstract Main conclusion OsJAZ11 regulates phosphate homeostasis by suppressing jasmonic acid signaling and biosynthesis in rice roots. Abstract Jasmonic Acid (JA) is a key plant signaling molecule which negatively regulates growth processes including root elongation. JAZ (JASMONATE ZIM-DOMAIN) proteins function as transcriptional repressors of JA signaling. Therefore, targeting JA signaling by deploying JAZ repressors may enhance root length in crops. In this study, we overexpressed JAZ repressor OsJAZ11 in rice to alleviate the root growth inhibitory action of JA. OsJAZ11 is a low phosphate (Pi) responsive gene which is transcriptionally regulated by OsPHR2. We report that OsJAZ11 overexpression promoted primary and seminal root elongation which enhanced Pi foraging. Expression studies revealed that overexpression of OsJAZ11 also reduced Pi starvation response (PSR) under Pi limiting conditions. Moreover, OsJAZ11 overexpression also suppressed JA signaling and biosynthesis as compared to wild type (WT). We further demonstrated that the C-terminal region of OsJAZ11 was crucial for stimulating root elongation in overexpression lines. Rice transgenics overexpressing truncated OsJAZ11ΔC transgene (i.e., missing C-terminal region) exhibited reduced root length and Pi uptake. Interestingly, OsJAZ11 also regulates Pi homeostasis via physical interaction with a key Pi sensing protein, OsSPX1. Our study highlights the functional connections between JA and Pi signaling and reveals JAZ repressors as a promising candidate for improving low Pi tolerance of elite rice genotypes.

scholarly journals Differential Effect of Jasmonic Acid and Abscisic Acid on Cell Cycle Progression in Tobacco BY-2 Cells

2002 ◽  
Vol 128 (1) ◽  
pp. 201-211 ◽  
Author(s):  
Agnieszka Świa̧tek ◽  
Marc Lenjou ◽  
Dirk Van Bockstaele ◽  
Dirk Inzé ◽  
Harry Van Onckelen
Keyword(s):  
Cell Cycle ◽  
Abscisic Acid ◽  
Jasmonic Acid ◽  
Differential Effect ◽  
Cell Cycle Progression ◽  
Cycle Progression

A reactive center loop–based prediction platform to enhance the design of therapeutic SERPINs

2021 ◽  
Vol 118 (45) ◽  
pp. e2108458118
Author(s):  
Wariya Sanrattana ◽  
Thibaud Sefiane ◽  
Simone Smits ◽  
Nadine D. van Kleef ◽  
Marcel H. Fens ◽  
...  
Keyword(s):  
Cleavage Site ◽  
Serine Proteases ◽  
Protein C ◽  
Activated Protein C ◽  
Reactive Center Loop ◽  
Physiological Processes ◽  
Naturally Occurring ◽  
Reactive Center ◽  
Insight Into

Serine proteases are essential for many physiological processes and require tight regulation by serine protease inhibitors (SERPINs). A disturbed SERPIN–protease balance may result in disease. The reactive center loop (RCL) contains an enzymatic cleavage site between the P1 through P1’ residues that controls SERPIN specificity. This RCL can be modified to improve SERPIN function; however, a lack of insight into sequence–function relationships limits SERPIN development. This is complicated by more than 25 billion mutants needed to screen the entire P4 to P4’ region. Here, we developed a platform to predict the effects of RCL mutagenesis by using α1-antitrypsin as a model SERPIN. We generated variants for each of the residues in P4 to P4’ region, mutating them into each of the 20 naturally occurring amino acids. Subsequently, we profiled the reactivity of the resulting 160 variants against seven proteases involved in coagulation. These profiles formed the basis of an in silico prediction platform for SERPIN inhibitory behavior with combined P4 to P4’ RCL mutations, which were validated experimentally. This prediction platform accurately predicted SERPIN behavior against five out of the seven screened proteases, one of which was activated protein C (APC). Using these findings, a next-generation APC-inhibiting α1-antitrypsin variant was designed (KMPR/RIRA; / indicates the cleavage site). This variant attenuates blood loss in an in vivo hemophilia A model at a lower dosage than the previously developed variant AIKR/KIPP because of improved potency and specificity. We propose that this SERPIN-based RCL mutagenesis approach improves our understanding of SERPIN behavior and will facilitate the design of therapeutic SERPINs.

scholarly journals Arabidopsis SIGMA FACTOR BINDING PROTEIN1 (SIB1) and SIB2 inhibit WRKY75 function in abscisic acid-mediated leaf senescence and seed germination

2021 ◽  
Author(s):  
Haiyan Zhang ◽  
Liping Zhang ◽  
Yunrui Ji ◽  
Yifen Jing ◽  
Lanxin Li ◽  
...  
Keyword(s):  
Abscisic Acid ◽  
Seed Germination ◽  
Leaf Senescence ◽  
Chromatin Immunoprecipitation ◽  
Sigma Factor ◽  
Dependent Manner ◽  
Negative Regulators ◽  
Factor Binding ◽  
Physiological Processes ◽  
Increased Sensitivity

Abstract The plant-specific VQ gene family participates in diverse physiological processes but little information is available on their role in leaf senescence. Here, we show that the VQ motif-containing proteins, Arabidopsis SIGMA FACTOR BINDING PROTEIN1 (SIB1) and SIB2 are negative regulators of abscisic acid (ABA)-mediated leaf senescence. Loss of SIB1 and SIB2 function resulted in increased sensitivity of ABA-induced leaf senescence. In contrast, overexpression of SIB1 significantly delayed this process. Moreover, biochemical studies revealed that SIBs interact with WRKY75 transcription factor. Loss of WRKY75 function decreased sensitivity to ABA-induced leaf senescence, while overexpression of WRKY75 significantly accelerated this process. Chromatin immunoprecipitation assays revealed that WRKY75 directly binds to the promoters of GOLDEN 2-LIKE1(GLK1) and GLK2, to repress their expression. SIBs repress the transcriptional function of WRKY75 and negatively regulate ABA-induced leaf senescence in a WRKY75-dependent manner. In contrast, WRKY75 positively modulates ABA-mediated leaf senescence in a GLK-dependent manner. In addition, SIBs inhibit WRKY75 function in ABA-mediated seed germination. These results demonstrate that SIBs can form a complex with WRKY75 to regulate ABA-mediated leaf senescence and seed germination.

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