Kolaviron, a Biflavonoid Compound: Pharmacological activity and Therapeutic Efficacy

2021 ◽  
Vol 18 ◽  
Author(s):  
Damilare Rotimi ◽  
Jennifer Chidubem Amanze ◽  
Adebola Busola Ojo ◽  
Matthew Iyobhebhe ◽  
Tobiloba Christiana Elebiyo ◽  
...  
Keyword(s):  
Therapeutic Efficacy ◽  
Treatment Options ◽  
Herbal Remedies ◽  
Clinical Settings ◽  
Garcinia Kola ◽  
Anti Cancer ◽  
The World ◽  
Health Promoting ◽  
Grown Plant ◽  
Viable Treatment

Abstract: The use of herbal remedies for medicinal purposes is becoming more popular around the world. As a result, plants have become viable treatment options for a variety of diseases. Garcinia kola (bitter kola) is a perennially grown plant in the Guttiferae family that has been evaluated and reported to have numerous health-promoting properties. Kolaviron is a biflavanoid and major phytochemical found in Garcinia kola that includes Garcinia Biflavanoid-1 (GB-1), kolaflavanone, and Garcinia Biflavanoid-2 (GB-2). It is obtained as a fraction extracted from Garcinia kola. Kolaviron's pharmacological properties include anti-inflammatory, anti-spasmodic, ameliorative, anti-asthmatic, anti-cancer, anti-malarial, hepatoprotective, antioxidant, anti-atherogenic, neuroprotective, anti-diabetic, and anti-amnesic properties. Kolaviron is recommended for use in clinical settings because it has been shown to have a high therapeutic efficacy in clinical trials. The purpose of this review is to assess the therapeutic efficacy of kolaviron.

scholarly journals Myristica fragrans (Jaiphal): A Significant Medicinal Herbal Plant

2021 ◽  
Vol 8 (2) ◽  
pp. 213-224
Author(s):  
Isha Kumari ◽  
Hemlata Kaurav ◽  
Gitika Chaudhary
Keyword(s):  
Herbal Remedies ◽  
Herbal Drugs ◽  
Myristica Fragrans ◽  
Therapeutic Uses ◽  
Wide Range ◽  
Anti Cancer ◽  
The World ◽  
Anti Oxidant ◽  
Myristica Fragrans Houtt ◽  
Herbal Plant

The tradition of using herbal drugs and herbal remedies for treating human ailments is very old. From last few years, the demand of herbal remedies has been increased. Myristica fragrans Houtt, commonly known as nutmeg, is a very common spice, which is used around the world. It is described in almost each medicine system such as Ayurveda, Siddha, Unani and folk system. It has wide range of fixed oils and essential oils in it for example myristicin, safrole, myristic acid, trimyristicin, eugenol, elimicin and meso-dihydroguaiaretic acid. Myristica fragrans Houttis well considered medicinal plant for its extraordinary properties like aphrodisiac, hepatoprotective, antimicrobial, anti-diabetic, anti-oxidant, anti-cancer etc. The review aim is to provide data/information related to medicinal herbal plant called Myristica fragrans such as its phytomedicinal value in traditional medicine systems like Ayurveda and folk system, its therapeutic uses and associated toxicity.

scholarly journals The Potential use of Honey as a Remedy for Allergic Diseases: A Mini Review

2021 ◽  
Vol 11 ◽  
Author(s):  
Poi Yi Aw Yong ◽  
Fahmida Islam ◽  
Hanis Hazeera Harith ◽  
Daud Ahmad Israf ◽  
Ji Wei Tan ◽  
...  
Keyword(s):  
Inflammatory Cells ◽  
Allergic Diseases ◽  
World Population ◽  
Clinical Settings ◽  
Allergic Reactions ◽  
Dietary Nutrients ◽  
Anti Cancer ◽  
The World ◽  
Therapeutic Properties ◽  
Potential Use

Honey has been conventionally consumed as food. However, its therapeutic properties have also gained much attention due to its application as a traditional medicine. Therapeutic properties of honey such as anti-microbial, anti-inflammatory, anti-cancer and wound healing have been widely reported. A number of interesting studies have reported the potential use of honey in the management of allergic diseases. Allergic diseases including anaphylaxis, asthma and atopic dermatitis (AD) are threatening around 20% of the world population. Although allergic reactions are somehow controllable with different drugs such as antihistamines, corticosteroids and mast cell stabilizers, modern dietary changes linked with allergic diseases have prompted studies to assess the preventive and therapeutic merits of dietary nutrients including honey. Many scientific evidences have shown that honey is able to relieve the pathological status and regulate the recruitment of inflammatory cells in cellular and animal models of allergic diseases. Clinically, a few studies demonstrated alleviation of allergic symptoms in patients after application or consumption of honey. Therefore, the objective of this mini review is to discuss the effectiveness of honey as a treatment or preventive approach for various allergic diseases. This mini review will provide insights into the potential use of honey in the management of allergic diseases in clinical settings.

ANTI-CANCER COMPOUNDS ISOLATED FROM SOFT CORAL SINULARIA CRUCIATA - ALCYONIIDAE

2012 ◽  
pp. 84-89
Author(s):  
Quoc Hung Vo ◽  
Nguyen Phuong Nhi Doan ◽  
Dinh Quynh Phu Nguyen ◽  
Thi Dieu Tram Ho ◽  
Thi Hoai Nguyen
Keyword(s):  
Mass Spectrometry ◽  
Soft Coral ◽  
Normal Phase ◽  
Ionization Mass ◽  
Medical Field ◽  
Bioactive Substances ◽  
Anti Cancer ◽  
The World ◽  
Pure Compounds ◽  
Layer Chromatography

Objectives: Nowadays, bioactive substances isolated from marine organisms which are abundant and varied in Vietnamese sea attracted more and more the attention of scientists in the world and Vietnam as well. We have studied on soft coral Sinularia cruciata – Alcyoniidae, which has never been studied in Vietnam before, to find substances which are useful in medical field, especially in anti-cancer therapy. Materials and method: Specimens of soft coral Sinularia cruciata were collected from Con Co, Quang Tri province in May 2011. Pure compounds were isolated by using Thin Layer Chromatography; Column Chromatography normal phase and inverse phase; Shephadex LH 20. Structures of them were determined by spectral data of Nuclear Magnetic Resonance (NMR), Electrospray Ionization Mass Spectrometry (ESI-MS). Results & Conclusion: Structures of 4 compounds were identified: (1) 5.8-epidioxycholest-6-en-3-ol (2) Cholesterol (3) 1-O-hexadecyl-glycerol (Chimyl alcohol) (4) Glycerol 1-O-octadecyl ether (Batyl alcohol). The substance (1) was demonstrated to have strong anti-cancer effects in previous study. Key words Sinularia cruciata, Alcyoniidae, 5,8-epidioxycholest-6-en-3-ol, soft coral, cancer.

Treatment Options in COVID-19: The Role of Bioavailable Antiviral Ribonucleoside Analog on NHC in vitro

2020 ◽  
Author(s):  
Lara Bittmann
Keyword(s):  
World Health Organization ◽  
Clinical Picture ◽  
Treatment Options ◽  
World Health ◽  
Wuhan City ◽  
The World ◽  
Novel Coronavirus ◽  
Health Organization

On December 31, 2019, WHO was informed of cases of pneumonia of unknown cause in Wuhan City, China. A novel coronavirus was identified as the cause by Chinese authorities on January 7, 2020 and was provisionally named "2019-nCoV". This new Coronavirus causes a clinical picture which has received now the name COVID-19. The virus has spread subsequently worldwide and was explained on the 11th of March, 2020 by the World Health Organization to the pandemic.

The potential role of tea in periodontal therapy: An updated review

2020 ◽  
Vol 17 ◽  
Author(s):  
Ali Forouzanfar ◽  
Hamideh Sadat Mohammadipour ◽  
Fatemeh Forouzanfar
Keyword(s):  
Green Tea ◽  
Potential Role ◽  
Wide Spectrum ◽  
Periodontal Diseases ◽  
Herbal Remedies ◽  
World Population ◽  
Tea Leaves ◽  
The World ◽  
Green Tea Leaves

: Periodontal diseases are highly prevalent and can affect high percentage of the world population. Oxidative stress and inflammation plays an important role in the pathogenesis of periodontal diseases. Nowadays, more attention has been focused on the herbal remedies in the field of drug discovery. Green tea is an important source of polyphenol antioxidants, it has long been used as a beverage worldwide. The most interesting polyphenol components of green tea leaves that are related with health benefits are the catechins. Taken together this review suggested that green tea with its wide spectrum of activities could be a healthy alternative for controlling the damaging reactions seen in periodontal diseases.

Nigella Sativa: An immunity booster as pandemic treatment solution against SARS-CoV-2

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Afzal Hussain ◽  
Ashfaq Hussain ◽  
Chandan Kumar Verma
Keyword(s):  
Medicinal Plant ◽  
Therapeutic Efficacy ◽  
Nigella Sativa ◽  
Folk Medicine ◽  
The World ◽  
Immune Booster

: Nigella sativa (Family Ranunculaceae) is a common medicinal plant all across the world. It is quite popular in different traditional medicinal systems such as Unani, Ayurveda, Tibb, and Siddha. Oil and Seeds have a long tradition of folk medicine utilized in different medicinal systems and food. The seeds of N. Sativa have indeed been widely applied in the treatment of many diseases, ailments, and also the immune booster. Our goal primarily concentrated on the therapeutic efficacy of Nigella sativa in combating the COVID-19 pandemic.

scholarly journals The Quality and Health-Promoting Value of Meat from Pigs of the Native Breed as the Effect of Extensive Feeding with Acorns

Animals ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 789
Author(s):  
Magdalena Szyndler-Nędza ◽  
Małgorzata Świątkiewicz ◽  
Łukasz Migdał ◽  
Władysław Migdał
Keyword(s):  
Fatty Acid ◽  
Beneficial Effect ◽  
Meat Quality ◽  
Farm Animals ◽  
Feeding Method ◽  
Native Breed ◽  
The World ◽  
Health Promoting ◽  
Conventional Farm

The popularity of meat from animals of native breeds is growing all over the world, due to consumer belief regarding its higher quality compared to meat from industrial farm animals. In addition, the living conditions (welfare) are of great importance for consumers. We observed the effect of different ways of keeping and feeding pigs of the same conservative breed on the quality of meat and its health benefits. The aim of the study was to compare the meat quality from pigs of the native Złotnicka Spotted breed, fattened intensively or extensively (with conventional farm-produced compound feed and acorns). The meat from free-range pigs extensively fed on silage and small amounts of acorns was characterized by a higher content of fat, which acts as a carrier for flavor and juiciness, as well as higher monounsaturated fatty acid (MUFA) content (p ≤ 0.05) and lower atherogenic, thrombogenic, and peroxidability indices (p ≤ 0.05). It may be stated that the meat quality of the native pig breed is significantly dependent on the housing and feeding method. A more beneficial effect on the quality of meat and its dietetic value, as well as its susceptibility to rancidity, can be obtained throughextensive pig feeding with roughage and the addition of acorns.

scholarly journals A review of post infectious pulmonary fibrosis in the era of COVID-19 and potential treatment options

2021 ◽  
Vol 9 (40) ◽  
pp. 37-46
Author(s):  
Medha Ghose ◽  
Maehali Patel
Keyword(s):  
Risk Factors ◽  
Pulmonary Fibrosis ◽  
Treatment Options ◽  
World Health ◽  
Potential Treatment ◽  
Pulmonary Injury ◽  
The World ◽  
Health Organization ◽  
Post Infectious

On March 11, 2020, the World Health Organization (WHO) released a statement characterizing COVID-19 as a pandemic that has, as of October 2020, caused almost 36 million confirmed global cases and over 1 million deaths. One of the long-term complications suggested by researchers is fibrosis. It has been hypothesized that the combination of ongoing pulmonary injury caused by COVID-19 and the inability to promptly repair damage results in interstitial matrix widening and eventual compression and destruction of alveoli and capillaries. Here we focus on pathogenesis, risk factors, different infectious causes of fibrosis along with COVID-19, and potential treatment options that might reduce its effects. Key words: COVID-19, pulmonary fibrosis, mechanism, treatment

Dance Movement Therapy in Healthcare

2017 ◽  
pp. 738-756
Author(s):  
Iris Bräuninger ◽  
Gonzalo Bacigalupe
Keyword(s):  
Treatment Options ◽  
Movement Therapy ◽  
Dance Movement Therapy ◽  
Relevant Research ◽  
Dance Movement ◽  
Healthcare Settings ◽  
Current State ◽  
Wide Range ◽  
Treatment Documentation ◽  
Viable Treatment

Is dance movement therapy (DMT) a viable treatment modality in health care? It is well established as a form of complementary medicine. More recently, oncology, neurology, and geriatrics—especially dementia treatment— have adopted DMT, and this chapter reviews these applications in preventive, curative, rehabilitative, and promotional healthcare. The current state of relevant research is summarized, and practical vignettes illustrate treatment options in various healthcare settings with a wide range of populations. Opportunities for assessment, treatment documentation, and evaluation are highlighted. The chapter’s summary addresses DMT’s contribution to healthcare in promoting wellbeing.

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