scholarly journals A 12-Year Retrospective Survey of Management of Patients with Malignant Neoplasms in the Orbital Cavity in a Brazilian Cancer Hospital

2013 ◽  
Vol 7 (1) ◽  
pp. 140-145 ◽  
Author(s):  
Daniela Sirianni ◽  
Cláudio Rodrigues Leles ◽  
Elismauro Francisco Mendonça
Keyword(s):  
Cell Carcinoma ◽  
Malignant Tumors ◽  
Demographic Data ◽  
Malignant Neoplasms ◽  
Prosthetic Rehabilitation ◽  
Chi Square ◽  
Orbital Cavity ◽  
Cancer Hospital ◽  
Unmet Demand ◽  
Chi Square Test

Purpose: The aim of this study was to investigate the distribution of different types of malignant tumors in the orbital cavity, surgical treatments, and subsequent prosthetic rehabilitation. Materials and Methods: A retrospective sample of 269 charts of patients attending a public reference cancer hospital in Goiania, Goias, Brazil, between 1998 and 2009 was selected. Study variables included demographic data, clinical and histopathological features, and patient rehabilitation. Frequency analysis, chi-square test and multiple logistic regression were used for data analysis. Results: Patients’ age ranged from 1 to 92 years and 50.2% were female. The most prevalent tumors were basal cell carcinoma (58%), retinoblastoma (17.1%), squamous cell carcinoma of the conjunctiva (7.1%), malignant melanoma (6.7%), and rhabdomyosarcoma (4.5%). Surgical treatment was performed in 250 patients (92.3%), but only 29 patients (10.8%) received ocular prosthetic rehabilitation. Lower age (p<0.001) and enucleation surgery (p<0.001) were significantly associated with prosthetic rehabilitation. Conclusions: Results revealed high occurrence of mutilating interventions and low provision of prosthetic care, limited to younger patients who had undergone enucleation surgery. The high unmet demand for rehabilitation emphasizes the need to incorporate appropriate care for ocular and orbital deformities into the Brazilian public health system.

scholarly journals Prevalence of sleep – wake cycle disturbance among cancer patients of Bhaktapur cancer hospital, Nepal

2017 ◽  
Vol 6 (2) ◽  
pp. 6-13
Author(s):  
P Marita ◽  
R Acharya Pandey
Keyword(s):  
Cancer Patients ◽  
Sleep Disturbances ◽  
Demographic Data ◽  
Severity Index ◽  
Cross Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Cancer Hospital ◽  
Chi Square Test ◽  
Clinically Significant

 Cancer patients are at great risk for developing insomnia and disorders of the sleep-wake cycle. Insomnia is the most common sleep disturbance in this population and is most often secondary to physical and/or psychological factors related to cancer and/or cancer treatment. It is estimated that nearly 45% of cancer patients experience sleep disturbances; this is nearly three times the estimate of its occurrence in the general population. The purpose of the study is to determine the prevalence of sleep-wake cycle disturbance in patient receiving chemotherapy. A descriptive cross-sectional study was carried out in 2013. A total of 205 respondents, visiting Bhaktapur Cancer Hospital and who met criteria were purposively sampled and interviewed face to face. Insomnia Severity Index Scale was used to grade insomnia. Descriptive statistics such as frequency and percentage was used to describe demographic data. Chi-square test was done to find out the association between prevalence of sleep-wake cycle disturbance and selected variables. Among the total respondents (205), 70.7% had sleep-wake cycle disturbances. Majority (71.21%) of respondents had some form of clinically significant insomnia. The ages of the respondents ranged from 20 to 81 years with the mean age of 56.25 (SD ± 13.87). More than half i.e. 69.3% of the respondents were female. Patients being treated with Methotrexate were found to be more associated with the development of sleep-wake cycle disturbance. The significant association was found on drinking tea/coffee with the prevalence sleep-wake cycle disturbance. Sleep disorders are a common and often chronic problem for patients with cancer. Recently, such symptoms have attracted little attention. This might be the reasons for increased prevalence of sleep-wake cycle disturbance. It is recommended to take early and adequate intervention for the reduction of increased prevalence rate of sleep-wake cycle disturbance. 

scholarly journals Oro-facial malignancy in north of Iraq: a retrospective study of biopsied cases

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sura Ali Ahmed Fuoad ◽  
Dena Nadhim Mohammad ◽  
Marwa Abdul-Salam Hamied ◽  
Balkees Taha Garib
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Demographic Data ◽  
Chi Square ◽  
Old Patients ◽  
Significant Difference ◽  
Chi Square Test ◽  
Oral Malignancies

Abstract Background Identifying the prevalence of orofacial malignancies is essential to provide health-care programs and services for a specific population. This study aimed to specify the prevalence, clinical and histopathological features of oral malignancies in Sulaimani for over 12 years. Methods All archived reports for orofacial specimens from 2008 to 2019 were collected from three major centers in Sulaimani governorate. The demographic data, date, type of surgery, lesion's site, and diagnosis were recorded. The ICD-10 coding was specified for each case. A Chi-square test was used to assess differences between genders. A one-way ANOVA test was applied to analyze the differences in mean age distributions among different sites of oral malignancies and oral squamous cell carcinoma histopathological grades. P < 0.05 was considered significant. Results Orofacial malignant lesions account for 14.53% of the total sample. Patients' mean age was (55.46 ± 18.48) years, and they were predominantly males (M: F ratio = 1.15:1). The tongue was the frequently affected site (14.8%). A Chi-square test showed no significant difference between genders concerning age (P = 0.118), years of registration (P = 0.28), and site (P = 0.29). The C06 (represents; cheek mucosa C06.0, the vestibule of mouth C06.1, retromolar area C06.2, and other unspecified parts of mouth C06.8) was the most frequent topographical ICD-code (18.1%). Carcinoma was a frequent malignancy (63.2%). OSCC was the most common lesion (56.4%). It commonly affects males, and the tongue was the frequent site (24.1%) followed by lip (17.8%). Conclusions There is a slight increase in the registered oral malignancies in Sulaimani city over 12 years; they were predominated in males, in 61–70 years old patients, and being oral squamous cell carcinoma types.

scholarly journals PROGNOSTIC FACTORS OF RENAL TUMOR RECURRENCE AFTER RADICAL NEPHRECTOMY

2021 ◽  
Vol 108 (Supplement_3) ◽  
Author(s):  
G Martínez Izquierdo ◽  
A R Arnaiz Pérez ◽  
E Escolano Fernández ◽  
M Merayo Álvarez ◽  
B Carrasco Aguilera ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Prognostic Factors ◽  
Radical Nephrectomy ◽  
Univariate Analysis ◽  
Malignant Neoplasms ◽  
Histopathological Analysis ◽  
Chi Square ◽  
Renal Sinus ◽  
Chi Square Test

Abstract INTRODUCTION Renal cell carcinoma (RCC) represents 3% of overall malignant neoplasms in adults. However, its aetiology has not been clearly established. Although surgery represents the cornerstone in treatment, recurrence postoperative rates are around 20-30%, what implies prognostic factors search must be mandatory in order to help to plan de follow-up and the different adjuvant therapy possibilities available in case they were necessary. MATERIAL AND METHODS A retrospective observational study was carried out in 110 patients who underwent radical nephrectomy between 2004 and 2018, with the aim of identifying possible prognostic factors of recurrence of RCC after these surgeries. Preoperative data (epidemiological, comorbidities and laboratory tests), surgical, pathological and variables related to follow-up were taken into account. A univariate and multivariate analysis were performed, using chi-square test and logistic regression, respectively. RESULTS The median follow-up time was 53.5 months (SD = 35.8), time in which 19 patients had a recurrence of RCC after radical nephrectomy (17.2%). Histopathological items such as the surgical piece size, the nodal and microvascular invasion, the renal sinus invasion and the presence of necrosis in the surgical piece were associated with RCC recurrence in the univariate analysis, while only the presence of necrosis in the surgical piece showed a significant result in the multivariate analysis (p = 0.004). CONCLUSIONS Histopathological analysis, highlighting the presence of necrosis in the histological sample, was proved to be the main risk factor of RCC recurrence.

Survivin Expression in Metastatic and Nonmetastatic Oral Squamous Cell Carcinoma: A Comparative Study

2020 ◽  
pp. 232020682096844
Author(s):  
B. Sekar ◽  
K. Indrapriyadharshini ◽  
M. Ambika ◽  
R. Saranyan ◽  
Madhavan Nirmal ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Survivin Expression ◽  
Staining Intensity ◽  
Fetal Tissue ◽  
Chi Square ◽  
Multifunctional Protein ◽  
Chi Square Test

Aim: Survivin is a multifunctional protein chiefly involved in apoptosis and cell cycle regulation. Increased expression of survivin in tumors and fetal tissue determines its antiapoptotic activity. The aim of the study is to identify the immunoexpression of survivin in metastatic and nonmetastatic oral squamous cell carcinoma (OSCC) and also to evaluate and compare the expression of survivin in metastatic and nonmetastatic OSCC of buccal mucosa. Materials and Methods: In total, 40 histopathologically proven cases of OSCC, including 20 metastatic and 20 nonmetastatic cases, are selected. Among the 20 metastatic and nonmetastatic cases, 10 well-differentiated and 10 moderately differentiated squamous cell carcinoma cases were included and were subjected to immunohistochemical staining for survivin expression. The results were analyzed by SPSS version 11.5 using chi-square test. Results: The expression of survivin in metastatic and nonmetastatic tumors is 15%–70% and 15%–60%, respectively. When comparing the cases of moderately differentiated squamous cell carcinoma in metastatic and nonmetastatic tumors, 70% cases show moderate staining intensity. Conclusion: The survivin expression was comparatively high in metastatic OSCC. Also based on the aforementioned results, survivin expression was high in increasing grades of OSCC.

scholarly journals Study of perinatal outcome of foetuses with nuchal cord

2018 ◽  
Vol 7 (9) ◽  
pp. 3507
Author(s):  
Misbah M. Inamdar ◽  
Asmita N. Patil
Keyword(s):  
Perinatal Outcome ◽  
Demographic Data ◽  
Mode Of Delivery ◽  
Perinatal Outcomes ◽  
Common Finding ◽  
Chi Square ◽  
Cross Sectional ◽  
Nuchal Cord ◽  
Chi Square Test ◽  
Meconium Staining

Background: Entanglement of the umbilical cord around the foetal neck (nuchal cord) is a common finding at delivery, but its clinical relevance is not entirely clear. Nuchal cords have generally been considered to be rather benign. However, the insufficiency in data regarding the role of nuchal cord in foetal morbidity and mortality is a source of anxiety and frustration to both parturient and healthcare professionals. Considering the above facts the present study was taken up to establish the incidence of nuchal cord at delivery in the existing setup.Methods: This was a cross sectional comparative study conducted over a period of one year from May 2013 to April 2014. A total of 362 women were selected for the study. These women were briefed about the nature of the study and a written informed consent was obtained. The demographic data and obstetrical history were documented on predesigned proforma. The data obtained was analysed using percentages and comparison done using chi-square test for discrete variables.Results: Incidence of Nuchal Cord was 17.7% among study cases. Based on this study gestational age may have an effect on the presence of nuchal cord (p<0.05). Out of 64 cases with nuchal cord’, 11.4% of cases had meconium stained liquor present. 9.8% of cases with nuchal cord had FHR irregularity, which was significantly less as compared to 20.0% of cases who did not show FHR irregularity. This was statistically significant. (p=0.032). 18.7% of mother who showed presence of nuchal cord had delivery by caesarean section. 22.7% of cases with nuchal cord had NICU admissions, which was insignificantly more as compared to 17.0% of cases who did not have NICU admissions.Conclusions: Intrapartum events such as meconium staining of liquor and foetal heart rate irregularities were more commonly associated with nuchal cord but it did not affect the perinatal outcome. However, the mode of delivery was independent of the presence of nuchal cord, thereby reducing the morbidity to the mother. Hence nuchal cord is not associated with adverse perinatal outcomes and the presence of a nuchal cord per se is not found to be an indication of operative delivery.

Prosthetic use by persons with unilateral transfemoral amputation in a South African setting

2019 ◽  
Vol 43 (3) ◽  
pp. 276-283 ◽  
Author(s):  
Elzbeth Pienaar ◽  
Surona Visagie
Keyword(s):  
South African ◽  
Walking Distance ◽  
Western Cape ◽  
Prosthetic Rehabilitation ◽  
Transfemoral Amputation ◽  
Cross Sectional Survey ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
Study Population

Background: Due to limitations in provision of prosthetic care in South Africa, a screening tool to select transfemoral prosthetic candidates has been implemented. Objective: To describe prosthetic services, use and mobility of people with transfemoral amputation, identified as prosthetic candidates through the Guidelines for Screening of Prosthetic Candidates: Lower Limb, and to identify variables that might influence prosthetic use and mobility. Design: Cross-sectional survey. Methods: The study population included all adults who received their first prosthesis from the Orthotic and Prosthetic Centre in the Western Cape between 1 June 2011 and 31 December 2014. Data were collected, with an adapted version of the Prosthetic Profile of the Amputee, from 43 participants, through telephonic interviews. Descriptive and inferential analysis, with the chi-square test, was done. Results: The majority of participants were older than 50 years (77%). Most participants (35; 81%) used their prosthesis; however, only 42% (18) used it daily. A significant association ( p = 0.000) was found between prosthetic rehabilitation and self-reported prosthetic walking distance. Less than half of participants received prosthetic rehabilitation and only 10 (30%) could walk 500 steps and more without resting. Conclusion: Participants used their prosthetic leg, but experienced limitations in frequency of wear and mobility. Clinical relevance Current findings showed that participants’ prosthetic mobility was curtailed. In less-resourced settings, carefully selecting prosthetic candidates may be necessary to provide access to services. Prosthetic provision is advised to be followed up with prosthetic rehabilitation for favourable mobility outcomes.

scholarly journals Prevalence of Malignancies in Patients With Primary Aldosteronism

2016 ◽  
Vol 101 (4) ◽  
pp. 1656-1663 ◽  
Author(s):  
K. Lang ◽  
K. Weber ◽  
M. Quinkler ◽  
A. S. Dietz ◽  
H. Wallaschofski ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Primary Aldosteronism ◽  
Renal Cell ◽  
Malignant Tumors ◽  
Single Case ◽  
Case Reports ◽  
Strong Association ◽  
Malignant Neoplasms

Abstract Context: Primary aldosteronism (PA) is the most common cause of secondary hypertension. Aldosterone excess can cause DNA damage in vitro and in vivo. Single case reports have indicated a coincidence of PA with renal cell carcinoma and other tumors. However, the prevalence of benign and malignant neoplasms in patients with PA has not yet been studied. Patients and Design: In the multicenter MEPHISTO study, the prevalence of benign and malignant tumors was investigated in 335 patients with confirmed PA. Matched hypertensive subjects from the population-based Study of Health in Pomerania cohort served as controls. Results: Of the 335 PA patients, 119 (35.5%) had been diagnosed with a tumor at any time, and 30 had two or more neoplasms. Lifetime malignancy occurrence was reported in 9.6% of PA patients compared to 6.0% of hypertensive controls (P = .08). PA patients with a history of malignancy had higher baseline aldosterone levels at diagnosis of PA (P = .009), and a strong association between aldosterone levels and the prevalence of malignancies was observed (P = .03). In total, 157 neoplasms were identified in the PA patients; they were benign in 61% and malignant in 25% of the cases (14% of unknown dignity). Renal cell carcinoma was diagnosed in five patients (13% of all malignancies) and was not reported in controls. Conclusion: Compared to hypertensive controls, the prevalence of malignancies was positively correlated with aldosterone levels, tended to be higher in PA patients, but did not differ significantly.

scholarly journals The Importance Of A Consultation Liaison Psychiatry Service In General Hospitals: A Brazilian 6-Years Experience

2021 ◽  
Author(s):  
Yoichi Takaki Konno ◽  
Fernanda Menezes de Faria ◽  
Gisele Zocoller Seno ◽  
Vinicius dos Santos Sguerri ◽  
Ana Carolina Gonçalves Olmos ◽  
...  
Keyword(s):  
Medical Records ◽  
Treatment Plan ◽  
Demographic Data ◽  
Liaison Psychiatry ◽  
Chi Square ◽  
General Hospitals ◽  
Significant Difference ◽  
Chi Square Test ◽  
Consultation Liaison Psychiatry ◽  
Level Of Significance

Abstract Background: The importance of consultation-liaison psychiatry (CLP) services have been progressively growing in all general hospitals.Methods: Data were collected from medical records of patients treated by the CLP service, from 2014 to 2020, including clinical-demographic data, characteristics of hospitalization, reason for request, treatment plan, and clinical outcome. For these analyses, the chi-square test, z-test, and Kruskal-Wallis test were used. The level of significance was set at 5%.Results: A total of 2,742 consultation requests were evaluated by the psychiatry team. The number of requests made grew by 109.64% over the years. In 58.21% of cases, the patient was in the ward, and 33% were requested by Internal Medicine. There was a statistically significant difference (p <0.001) in the distribution of reasons for request according to patients' characterization variables.Conclusions: This study sought to analyze the functioning and growth of CLP in a tertiary Brazilian general hospital. The present findings reinforce the importance of this service and the need to implement and develop CLP in general hospitals.

scholarly journals Evaluation of possible reasons for not opting for fixed dental prosthesis: Patient and Practitioner Perspective

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 211-215
Author(s):  
Keshav Krishnaa P ◽  
Dhanraj Ganapathy ◽  
Adimulapu Hima Sandeep
Keyword(s):  
Treatment Options ◽  
Epidemiological Studies ◽  
Prosthetic Rehabilitation ◽  
Chi Square ◽  
Hygiene Practices ◽  
Fixed Dental Prosthesis ◽  
Removable Denture ◽  
Removable Prosthesis ◽  
Chi Square Test ◽  
Mandibular Teeth

With recent trends towards oral hygiene practices, the need for prosthetic rehabilitation has increased. There has been an increased spread of knowledge regarding the same as well as an increase in treatment options for the same. Epidemiological studies have shown that the anterior mandibular teeth usually are retained for the longest period, and the canines are the most persistent. Prosthetic rehabilitation of extracted teeth is important, and the choice of appropriate prosthesis is even more critical. There has been an increasing trend in the usage of removable options. The study aims to assess the different reasons to opt for a removable prosthesis than a fixed prosthesis. Retrospective data of 186 patients were obtained and segregated. Inclusion criteria included that they should be between 18 – 40 years, undergone removable denture therapy and should have visited during the period of the study. The data were tabulated, and the same was analyzed using SPSS by IBM version 20. The frequencies and cross-tabulations were performed, followed by correlation and association using the chi square test to check the correlation between the different variables. The results, thus obtained, were analyzed. Males (54.8%) undergo removable therapy more than females. Most common arch is upper arch (59.1%), the most common reason is to use a temporary denture (37.6%) Correlation seen between Arch and reason for not opting for FPD (p <0.05). The present study has revealed a lacuna in knowledge among patients and practitioners—further studies and programmes to be done to improve knowledge and help society.

scholarly journals Visibly Marked and Microchipped Lost Dogs Have a Higher Chance to Find Their Owners in Belgrade

2015 ◽  
Vol 38 (1) ◽  
pp. 79-83 ◽  
Author(s):  
Marijana Vučinić ◽  
Katarina Radisavljević ◽  
Alexandra Hammond-Seaman ◽  
Vlatko Ilieski
Keyword(s):  
Recovery Rate ◽  
Demographic Data ◽  
Demographic Characteristics ◽  
Data Bases ◽  
Chi Square ◽  
Animal Protection ◽  
Lost And Found ◽  
Chi Square Test

Abstract The aim of the study was to analyse the demographic characteristics of lost and found dogs in Belgrade, Serbia. The demographic data concerning the 246 lost and 81 found dogs in the period of 5 consecutive years (January, 2009 to January 2014) was sampled and analysed from the data bases of four organizations for animal protection in Belgrade. The recovery rate of lost dogs and the chance to be reunited again with their owners was 33%. The highest recovery rate was estimated in the category of lost dogs with visible marks such as tags or collars (30%).The chi-square test disclosed that besides dogs with special visible marks, significantly more females, light colour coated, friendly/sociable and neutered dogs were reunited with their owners (P<0.0001).

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