Epidemiology of Urinary Tract Infection in Neonatal Intensive Care Unit of Mohammed VI University Hospital in Marrakech

Objective: The objective of our study is to estimate the extent of urinary infection among neonatal infectious diseases. Materials and Methods: This work concerns a retrospective study of 91 newborns with urinary tract infections, collected in the Mohammed VI neonatal resuscitation unit, Marrakesh. Results: The average age of our newborns at admission was 10.8 days. In 20 cases, there were signs of maternal urinary tract infections. The main reason for hospitalization was jaundice in 72.53% of cases. The symptomatology was dominated by fever in 16.48% of cases, followed by a refusal to suck in 5.5% of cases. Escherichia coli was the predominant germ in 61.5% of cases. A probabilistic anti-biotherapy based on Ceftriaxone 3rd Generation and aminoglycoside was instituted in all cases after it was adapted to the antibiogram data. Ultrasound revealed malformations in 21 cases. Conclusion: Neonatal urinary tract infection remains a common pathology. Its potential severity involving renal functional prognosis and the frequency of urinary tract malformations require early diagnosis and adequate management.

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URINARY INFECTION AT DEPARTMENT OF UROLOGY OF HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2018.3.16 ◽

2018 ◽

pp. 100-108

Author(s):

Dinh Khanh Le ◽

Dinh Dam Le ◽

Khoa Hung Nguyen ◽

Xuan My Nguyen ◽

Minh Nhat Vo ◽

...

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Urine Culture ◽

Clinical Manifestations ◽

University Hospital ◽

E Coli ◽

Positive Urine ◽

Tract Infections

Objectives: To investigate clinical characteristics, bacterial characteristics, drug resistance status in patients with urinary tract infections treated at Department of Urology, Hue University Hospital. Materials and Method: The study was conducted in 474 patients with urological disease treated at Department of Urology, Hue Universiry Hospital from July 2017 to April 2018. Urine culture was done in the patients with urine > 25 Leu/ul who have symptoms of urinary tract disease or infection symptoms. Patients with positive urine cultures were analyzed for clinical and bacterial characteristics. Results: 187/474 (39.5%) patients had symptoms associated with urinary tract infections. 85/474 (17.9%) patients were diagnosed with urinary tract infection. The positive urine culture rate was 45.5%. Symptoms of UTI were varied, and no prominent symptoms. E. coli accounts for the highest proportion (46.67%), followed by, Staphycoccus aureus (10.67%), Pseudomonas aeruginsa (8,0%), Streptococcus faecali and Proteus (2.67%). ESBL - producing E. coli was 69.23%, ESBL producing Enterobacter spp was 33.33%. Gram-negative bacteria are susceptible to meropenem, imipenem, amikacin while gram positive are vancomycin-sensitive. Conclusions: Clinical manifestations of urinary tract infections varied and its typical symptoms are unclear. E.coli is a common bacterium (46.67%). Isolated bacteria have a high rate of resistance to some common antibiotics especially the third generation cephalosporins and quinolones. Most bacteria are resistant to multiple antibiotics at the same time. Gram (+) bacteria are susceptible to vancomycin, and gram (-) bacteria are susceptible to cefoxitin, amikacin, and carbapenem. Key words: urinary tract infection

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Bacterial uropathogens and susceptibility testing among patients diagnosed with urinary tract infections at Hiwot Fana Specialized University Hospital, Eastern Ethiopia

SAGE Open Medicine ◽

10.1177/20503121211001162 ◽

2021 ◽

Vol 9 ◽

pp. 205031212110011

Author(s):

Tewodros Tesfa ◽

Yohannes Baye ◽

Mekonnen Sisay ◽

Firehiwot Amare ◽

Tigist Gashaw

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

University Hospital ◽

Eastern Ethiopia ◽

Hypertensive Patients ◽

Microbiological Methods ◽

Tract Infections ◽

Culture Positive

Background: Urinary tract infection is a common infection posing a significant healthcare burden globally. Currently, it is becoming hard to manage due to the drug resistance of uropathogens. This study aimed to evaluate the rate of culture positivity and the susceptibility pattern of isolates among clinically diagnosed patients with urinary tract infection. Methods: An institution-based cross-sectional study was conducted on patients clinically diagnosed with urinary tract infections and received a drug prescription at Hiwot Fana Specialized University Hospital from August 2018 to June 2019. A clean-catch mid-stream urine specimen was collected and bacterial identification and susceptibility test were performed using standard microbiological methods. Data were entered into EpiInfo 7 and exported to STATA 15 for analysis. Data were analyzed using descriptive analysis and bi-variate and multivariate regression analyses and presented with graphs, frequency, and tables. Results: A total of 687 urine samples were collected from patients with clinically diagnosed urinary tract infections. The mean age was 31 years and 56.62% were female. 28.38% of the participants had a culture-positive result, of which 86.15% had monomicrobial infections. Inpatients (AOR = 3.8, 95% CI = (1.8–7.9)) and hypertensive patients (AOR = 2.1, 95% CI = (1.1–4.4)) had higher odds of culture-positive results. Staphylococcus species (35.3%), E. coli (25.34%), Pseudomonas species (6.8%), and other Enterobacterales are isolated. Most isolates showed resistance to more than one drug, and amikacin, gentamicin, and nitrofurantoin showed relatively higher activity against isolates. Conclusion: About one-third of the clinically diagnosed patients with urinary tract infection were culture-positive with many types of bacterial uropathogens. Inpatients and hypertensive patients had a higher risk of developing bacterial infections. Bacterial isolates showed different percentages of susceptibility to the tested antibiotics.

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Epidemiological, bacteriological profile and bacterial resistance of urinary tract infections at pregnant woman in prenatal consultation in African setting

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20200329 ◽

2020 ◽

Vol 9 (2) ◽

pp. 461

Author(s):

Koffi Abdoul Koffi ◽

Edèle Kacou Aka ◽

Horo Apollinaire ◽

Alice Mlan Britoh ◽

Jean Marie Perel Konan

Keyword(s):

Escherichia Coli ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Pregnant Women ◽

Urinary Tract Infections ◽

Significant Risk ◽

University Hospital ◽

First Choice ◽

Tract Infections

Background: Urinary tract infection is a common pathology during pregnancy due to hormonal and morphological changes. Objective of this study was to improve management of urinary tract infection during prenatal care.Methods: A total of 987 pregnant women who have been in prenatal care have freely accepted to participate in cross-sectional study carried out from 1st May 2016 to 30th April 2017 at Yopougon University Hospital (Abidjan Côte d’Ivoire) were included. Patients were submitted to questionnaire by one of investigators for epidemiological component and then physical examination was carried out by her attending physician for clinical component. Then at laboratory urine was taken for culture after dipstick test.Results: Of the 987 patients included 9.4% had a urinary tract infection of which 81.7% were asymptomatic. Significant risk factors retained were existence of a history of urinary tract infection (OR=0.46; p=0,038) and gestational age of pregnancy (OR=0.44; p=0.05). Urine culture isolated germs were mainly Escherichia Coli (51.6%) and Klebsiella pneumoniaie (23.6%). These germs were all susceptible to cephalosporins. They had resistances of more than 50% to penicillins.Conclusions: Escherichia coli and Klebsiella pneumoniae are most common germs of urinary tract infections in pregnant women. Escherichia coli is not susceptible to penicillins with a resistance of 70% for penicillins except for clavulanic acid amoxicillin. It appears as first choice antibiotic for our prescriptions in case of probabilistic antibiotic therapy.

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Detection of tox A gene in Pseudomonas aeruginosa that isolates from different clinical cases by using PCR.

Ibn AL- Haitham Journal For Pure and Applied Science ◽

10.30526/2017.ihsciconf.1767 ◽

2018 ◽

pp. 26

Author(s):

Rana M. Abdullah Al-Shwaikh ◽

Abbas Falih Alornaaouti

Keyword(s):

Molecular Weight ◽

Pseudomonas Aeruginosa ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Otitis Media ◽

Urinary Tract Infections ◽

Gel Electrophoresis ◽

Wound Infections ◽

Tract Infections

Current study obtained (75) isolate of Pseudomonas aeruginosa collected from different cases included : 28 isolates from otitis media, 23 isolates from burn infections, 10 isolates from wound infections, 8 isolates from urinary tract infections and 6 isolates from blood, during the period between 1/9/2014 to 1/11/2014 The result revealed that the tox A gene was present in 54 isolates (72%) of Pseudomonas aeruginosa. The gel electrophoresis showed that the molecular weight of tox A gene was 352 bp. The result shows 17 isolates (60.71%) from otitis media has tox A gene, 18 isolates (78.26%) from burn followed by 8 isolate (80%) from wound infection and 5 isolates (62.5%) from urinary tract infection , finally 6 isolates (100%) from blood have this gene.

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Measuring Antibiotic Appropriateness for Urinary Tract Infections in Nursing Home Residents

Infection Control and Hospital Epidemiology ◽

10.1017/ice.2017.96 ◽

2017 ◽

Vol 38 (8) ◽

pp. 998-1001 ◽

Cited By ~ 10

Author(s):

Taniece Eure ◽

Lisa L. LaPlace ◽

Richard Melchreit ◽

Meghan Maloney ◽

Ruth Lynfield ◽

...

Keyword(s):

Urinary Tract Infection ◽

Nursing Home ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Nursing Home Residents ◽

Infect Control Hosp ◽

Antibiotic Prescribing ◽

Appropriate Use ◽

Tract Infections

We assessed the appropriateness of initiating antibiotics in 49 nursing home (NH) residents receiving antibiotics for urinary tract infection (UTI) using 3 published algorithms. Overall, 16 residents (32%) received prophylaxis, and among the 33 receiving treatment, the percentage of appropriate use ranged from 15% to 45%. Opportunities exist for improving UTI antibiotic prescribing in NH.Infect Control Hosp Epidemiol 2017;38:998–1001

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Diagnosis of Urinary Tract Infection

PEDIATRICS ◽

10.1542/peds.50.6.975 ◽

1972 ◽

Vol 50 (6) ◽

pp. 975-975

Author(s):

James Kennedy Todd

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

False Positives ◽

Colony Count ◽

Tract Infections

The recent paper by Cohen in the August issue of Pediatisics relies on the use of "one or more cultures of over 100,000 organisms per millimeter of urine" to make the diagnosis of urinary tract infections upon which the remainder of the study is dependent. Obviously, the colony count was intended to read "per milliliter," and yet the results of the study must be seriously questioned since the criterion for diagnosis of urinary tract infection was not rigid enough to exclude a large number of false-positives— patients who never really had urinary tract infections.

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Larger Numbers Needed

PEDIATRICS ◽

10.1542/peds.80.5.764 ◽

1987 ◽

Vol 80 (5) ◽

pp. 764-764

Author(s):

THOMAS E. WISWELL

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

First Year ◽

Infection Rates ◽

Symptomatic Urinary Tract Infection ◽

Tract Infections ◽

First Year Of Life

In Reply.— Dr Altschul presents data on urinary tract infections during infancy and reports infection rates substantially lower than those we have previously reported.1,2 He then makes several conclusions based on these differences. His data indicate that the maximum infection rates would be 0.11% among girls and 0.02% and 0.12% among circumcised and uncircumcised boys, respectively. In contrast, from a population of 422,328 infants, we found the overall incidence of symptomatic urinary tract infection during the first year of life to be 0.57% in girls, 0.11% in circumcised boys, and 1.12% in uncircumcised boys.

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Infeções do Trato Urinário numa Coorte de Transplantados Renais

Acta Médica Portuguesa ◽

10.20344/amp.4959 ◽

2014 ◽

Vol 27 (3) ◽

pp. 364 ◽

Cited By ~ 2

Author(s):

Ana Bispo ◽

Milene Fernandes ◽

Cristina Toscano ◽

Teresa Marques ◽

Domingos Machado ◽

...

Keyword(s):

Risk Factors ◽

Escherichia Coli ◽

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Hospital Admissions ◽

Female Gender ◽

Tract Infections

Introduction: Urinary tract infection is the most common infectious complication following renal transplantation and its frequency is insufficiently studied in Portugal. The aim of this study was to characterize the incidence of urinary tract infections and recurrent urinary tract infections in renal transplant recipients. Material and Methods: This was a retrospective cohort observational study, obtained from clinical files of all patients who received a renal transplant at the Hospital of Santa Cruz, from January 2004 to December 2005, with a mean follow-up period of five years or until date of graft loss, death or loss of follow-up. After a descriptive analysis of the population, we used bivariate tests to identify risk factors for urinary tract infections. Results: A total of 127 patients were included, with a 593 patients.year follow-up. We detected 53 patients (41.7%) presenting with at least one episode of urinary tract infection; 21 patients (16.5%) had recurrent urinary tract infection. Female gender was the only risk factor associated with the occurrence of urinary tract infections (p < 0.001, OR = 7.08, RR = 2.95) and recurrent urinary tract infections (p < 0.001, OR = 4.66, RR = 2.83). Escherichia coli (51.6%), Klebsiella pneumoniae (15.5%) and Enterobacter spp (9.9%) were the most frequently identified pathogens. Patients did not reveal an increased mortality or allograft loss. However, urinary tract infections were the most important cause of hospital admissions. Discussion: Female gender was the only risk factor for urinary tract infections in this population. Escherichia coli was the most frequent agent isolated. Conclusion: Despite preventive measures, urinary tract infections remain an important cause of morbidity and hospital admissions. Keywords: Urinary Tract Infections; Postoperative Complications; Risk Factors; Kidney Transplantation; Portugal.

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Emerging Role of Microbiome in the Prevention of Urinary Tract Infections in Children

International Journal of Molecular Sciences ◽

10.3390/ijms23020870 ◽

2022 ◽

Vol 23 (2) ◽

pp. 870

Author(s):

Anna Kawalec ◽

Danuta Zwolińska

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Pediatric Population ◽

Urologic Diseases ◽

Increased Risk ◽

Tract Infections ◽

The Impact

The microbiome of the urinary tract plays a significant role in maintaining health through the impact on bladder homeostasis. Urobiome is of great importance in maintaining the urothelial integrity and preventing urinary tract infection (UTI), as well as promoting local immune function. Dysbiosis in this area has been linked to an increased risk of UTIs, nephrolithiasis, and dysfunction of the lower urinary tract. However, the number of studies in the pediatric population is limited, thus the characteristic of the urobiome in children, its role in a child’s health, and pediatric urologic diseases are not completely understood. This review aims to characterize the healthy urobiome in children, the role of dysbiosis in urinary tract infection, and to summarize the strategies to modification and reshape disease-prone microbiomes in pediatric patients with recurrent urinary tract infections.

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The Prevalence of Bacterial Pathogens associated with Urinary Tract Infection (UTI) among Patients attending Kam Medical Consult Clinic, Uganda.

10.51168/sjhrafrica.v2i6.35 ◽

2021 ◽

Author(s):

◽

Gerald Turyatunga

Keyword(s):

Urinary Tract Infection ◽

Urinary Tract ◽

Tract Infection ◽

Urinary Tract Infections ◽

Bacterial Pathogens ◽

Clinical Signs ◽

Cross Sectional Study ◽

Cross Sectional ◽

Etiological Agents ◽

Tract Infections

Background: A urinary tract infection (UTIs) is a common type of infection caused by bacteria that travel up the urethra to the bladder. Globally, it is reported that 150 million people are diagnosed with a UTI annually, costing the world economy over 6 million US dollars in treatment and work loss. Studies conducted in the in-patients pediatric ward of Muhimbili Hospital in Tanzania and Mulago National Referral Hospital in Uganda between five to ten years reported the prevalence of UTI to be 16.8% and 14.6% respectively. On average at Kam Medical Consult Clinic, patients who turn up in the laboratory are about 20%, and 50% of patients present with recurring UTIs clinically. Therefore, there is a need to establish and investigate the prevalence of bacterial pathogens associated with UTI and multiple pathogens that are not known. Methodology: The cross-sectional study was carried out at Kam medical consult clinic (KMCC) located in Kafeero zone Mulago II Kawempe division. The study population was adults and children presenting with symptoms of urinary tract infection. 120 Midstream urine Samples were collected from patients presenting clinical signs of UTI. The diagnosis was done through macroscopy dry chemistry, microscopy, and culture. Results Among the sampled population, 33% of males had urinary tract infections while 67% of females had urinary tract infections. 88.5% were outpatients while 11.5 % were in-patients The overall prevalence of UTI among patients was 63.3% with children aged (1-10) having a prevalence of 5.8 %. Conclusion and recommendation: E.coli is an etiological agent causing UTIs in male and female patients presenting UTI at Kam Medical Consult Clinic. Other etiological agents included Klebsiella, Coliform, Enterococcus species, staphylococcus aureus, pseudomonas species, and candida species. There is a need to monitor the profile of etiological bacteria of UTI through culture and sensitivity regularly.

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