Primary Hypothyroidism in Adults Based on Jorjani's View Point of the Book “Zakhire Kharazmshahi”

2019 ◽  
Vol 06 ◽  
Author(s):  
Haleh Tajadini ◽  
Naser Ebrahimpour ◽  
Mahdieyh Khazaneha

: The prevalence of primary hypothyroidism is increasing in adults (PHTA), and the reduction in the threshold for treatment and also the requirement to increase drug usage are major problems in approaching this disorder. Persian Medicine (PM) looks from a different view on etiology of diseases. Therefore, we tried to present the etiologies of PHTA according to an important book of PM i.e. “Zakhire Kharazmshahi”. Method: At first, the common symptoms and signs of PHTA were identified by investigating the Medline, Scopus, and Cochrane databases and their Persian equivalents were extracted from PM sources. These synonyms were searched as keywords in the book and the primary causes that were mentioned in association with the signs and symptoms were extracted. Then, we explained the total etiologies that were discussed for the occurrence of the causes, with respect to the principles of health care in PM. Results: "Cold distemperament", an increase in "Phlegmatic Humor ", an increase in "Melancholic Humor" and "Emtela" (repletion) were recognized as four main causes of PHTA. According to the book, the most important etiologies of these conditions are insufficient exercise, overeating, food intake before total stomach emptying and excessive amounts of cold temperament substances (foods, herbs, seeds, spices, etc.) in daily diet. Conclusion: From the viewpoint of PM, lifestyle spatially eating habits and physical activity play important causative roles in occurring and prognosis of PHTA. Hence, it is recommended to assess these results by more observations and clinical studies.

Author(s):  
Amandeep Kaur ◽  
Harmanpreet Singh ◽  
Suksham Gupta ◽  
Jasjeet Kaur Narang ◽  
Yash Paul Singla ◽  
...  

  Objective: A brain disease, migraine is a special type of headache that causes highly intense, throbbing quality pain in half head or any one side of the head. It may be due to several reasons such as food intake, sleep disturbance, and stress or tension. Hormonal disturbance can result in migraine. There is no specific treatment for migraine. Analgesics or pain killers may prove effective in migraine. To prevent it cautions must be taken. Our study aims to find out the awareness and prevalence of migraine among students of different schools, colleges, universities, and professional institutes of Jalandhar city. Further, the drug consumption pattern of most prominent used antimigraine medications was also calculated.Method: The cross–sectional data were collected through a questionnaire from the random sample in the month from August 2016 to November 2016 in Jalandhar. To check the drug consumption, daily defined dose (DDDs) or drug usage has been calculated using the DDD recommended by the World Health Organization.Results: According to our survey, 80% candidates have heard about the term “migraine.’’ 36% candidates are aware about the causes, 58% aware about the signs and symptoms of migraine while 23% candidates are aware about the treatment. The overall awareness rate of migraine in candidates is about 45%.Conclusion: The prevalence of migraine is more in women than men by a factor of about 3:1. Triptans are mostly found to be effective for the treatment of migraine. The main cause of migraine was found to be stress or tension and the common symptom of migraine was throbbing or pulsating pain on one side of the head.


2001 ◽  
Vol 11 (4) ◽  
pp. 311-321
Author(s):  
DN Carmichael ◽  
Michael Lye

Heart failure has been defined in many ways and definitions change over time. The multiplicity of definitions reflect the paucity of our understanding of the primary underlying physiology of heart failure and the many diseases for which heart failure is the common end-point. Fundamentally, heart failure represents a failure of the heart to meet the body’s requirement for blood supply for whatever reason. It is thus a clinical syndrome with characteristic features – not a single disease in its own right. The syndrome includes symptoms and signs of organ underperfusion, fluid retention and neuroendocrine activation. The syndrome arises from a range of possible causes of which ischaemic heart disease is the commonest. From the point of view of a clinician, the underlying pathology will determine treatment options and prognosis. The extensive range of possible aetiologies present a diagnostic challenge both to correctly identify the syndrome amongst all other causes of dyspnoea and to identify the aetiology, allowing optimization of treatment.


2003 ◽  
Vol 22 (12) ◽  
pp. 665-668 ◽  
Author(s):  
Hüseyin Çaksen ◽  
Dursun Odabaş ◽  
Sinan Akbayram ◽  
Yaşar Cesur ◽  
Şükrü Arslan ◽  
...  

Deadly nightshade (Atropa belladonna) intoxication has been infrequently reported in both children and adults in the literature. In this article, the clinical and laboratory findings of 49 children with acute deadly nightshade intoxication are reviewed. Our purpose was to enlighten the findings of deadly nightshade intoxication in childhood. The most common observed symptoms and signs were meaningless speech, tachycardia, mydriasis, and flushing. None of the children required mechanical ventilation or died in our series. The patients were categorized into two groups, mild/moderate and severe intoxication. Children with and without encephalopathy were accepted as severe and mild/moderate intoxication, respectively. While 43 children were placed in the group of mild/moderate intoxication, six were in severe intoxication group. We found that meaningless speech, lethargy, and coma were more common, but tachycardia was less common in the severe intoxication group (children with encephalopathy) (P B-0.05). In the treatment, neostigmine was used in all children because of no available physostigmine in our country. In conclusion, our findings showed that the initial signs and symptoms of acute deadly nightshade intoxication might be severe in some children, but no permanent sequel and death were seen in children. We also showed that meaningless speech, lethargy, coma, and absence of tachycardia were ominous signs in deadly nightshade intoxication in childhood. Lastly, we suggest that neostigmine may be used in cases of deadly nightshade intoxication if physostigmine cannot be available.


PEDIATRICS ◽  
1967 ◽  
Vol 40 (6) ◽  
pp. 962-974
Author(s):  
W. A. Aherne ◽  
K. W. Cross ◽  
E. N. Hey ◽  
Sheila R. Lewis

Detailed lung function studies at the age of 8 months and 1 year are reported for an infant who weighed 992 gm at birth and who developed chronic progressive pulmonary insufficiency 2 weeks after birth. The symptoms and signs were similar to those described by Wilson and Mikity in 1960. A confirmatory lung biopsy was obtained when the child was 11 months old. Dynamic lung "compliance" was very significantly reduced while a static estimate of lung compliance was within normal limits. These and other lung function findings are interpreted as indicating that uneven alveolar ventilation was the probable functional basis for all the signs and symptoms observed.


2012 ◽  
Vol 24 (2) ◽  
pp. 134-139 ◽  
Author(s):  
Priscila Weber ◽  
Eliane Castilhos Rodrigues Corrêa ◽  
Fabiana dos Santos Ferreira ◽  
Juliana Corrêa Soares ◽  
Geovana de Paula Bolzan ◽  
...  

PURPOSE: To study the frequency of cervical spine dysfunction (CCD) signs and symptoms in subjects with and without temporomandibular disorder (TMD) and to assess the craniocervical posture influence on TMD and CCD coexistence. METHODS: Participants were 71 women (19 to 35 years), assessed about TMD presence; 34 constituted the TMD group (G1) and 37 comprised the group without TMD (G2). The CCD was evaluated through the Craniocervical Dysfunction Index and the Cervical Mobility Index. Subjects were also questioned about cervical pain. Craniocervical posture was assessed by cephalometric analysis. RESULTS: There was no difference in the craniocervical posture between groups. G2 presented more mild CCD frequency and less moderate and severe CCD frequency (p=0.01). G1 presented higher percentage of pain during movements (p=0.03) and pain during cervical muscles palpation (p=0.01) compared to G2. Most of the TMD patients (88.24%) related cervical pain with significant difference when compared to G2 (p=0.00). CONCLUSION: Craniocervical posture assessment showed no difference between groups, suggesting that postural alterations could be more related to the CCD. Presence of TMD resulted in higher frequency of cervical pain symptom. Thus the coexistence of CCD and TMD signs and symptoms appear to be more related to the common innervations of the trigeminocervical complex and hyperalgesia of the TMD patients than to craniocervical posture deviations.


2011 ◽  
Vol 69 (5) ◽  
pp. 751-755 ◽  
Author(s):  
Mariana Moscovich ◽  
Felipe T.M. Nóvak ◽  
Artur F. Fernandes ◽  
Tatiana Bruch ◽  
Tabita Tomelin ◽  
...  

Neuroleptic malignant syndrome (NMS) is a potentially fatal adverse event associated with the use of antipsychotics (AP). The objective of this study was to investigate the profile of cases of NMS and to compare our findings with those published in similar settings. A series of 18 consecutive patients with an established diagnosis of NMS was analyzed, gathering data on demography, symptoms and signs. Two thirds of all cases involved woman with a past medical history of psychiatric disorder receiving relatively high doses of AP. The signs and symptoms of NMS episodes were similar to those reported in other series and only one case had a fatal outcome, the remaining presenting complete recovery. As expected, more than two thirds of our cases were using classic AP (68%), however the clinical profile of these in comparison with those taking newer agent was similar. Newer AP also carry the potential for NMS.


2017 ◽  
Vol 11 (02) ◽  
pp. 258-263
Author(s):  
Noriko Suzuki ◽  
Hitoshi Oguchi ◽  
Yu Yamauchi ◽  
Yasuyo Karube ◽  
Yukimi Suzuki ◽  
...  

ABSTRACTThis case report aimed to report the progress of preservation therapy and response of symptoms and signs for Stage 0 of bisphosphonate-related osteonecrosis of jaw (BRONJ). A 68-year-old female was recognized having a tooth at the left upper first molar fracture upon medicating bisphosphonate (BP) in 2007. At that time, the extraction of the tooth was an absolute contraindication. Therefore, we performed preservation therapy. We observed the symptoms and signs every month. After 5 months, swelling and redness in the entire first molar tooth were seen and fistula formed partly. Bone exposure was not seen. We administrated antibiotics immediately. As a result, symptoms disappeared. On April 10, 2009, the patient visited us as she felt a sense of incongruity in the lower left first and second molar teeth. Clinically, there were no symptoms of pain. However, we observed the radiolucent finding in about 5 mm diameter at apical position by X-ray photography; we considered a possibility of Stage 0 for BRONJ. We immediately administered medicine for 5 days and the symptoms disappeared. At present, no inflammation with signs and symptoms at the upper left first molar and lower left first, second molar parts is shown. We performed preservation therapy for tooth fracture case medicating of BP. Immediate responses for inflammation and symptoms of the Stage 0 of BRONJ have led to success. Hence, dentists should perform regular clinical observation, and enough education to the patient for BRONJ is necessary.


2009 ◽  
Vol 10 (4) ◽  
pp. 75-82 ◽  
Author(s):  
Foluso J. Owotade ◽  
Morenike O. Folayan ◽  
Temitope A. Esan ◽  
Elizabeth O. Oziegbe ◽  
Comfort A. Adekoya-Sofowora

Abstract Aim To determine signs and symptoms associated with teething, parental beliefs about teething, and the effects of socioeconomic status on teething in Nigerian children. Methods and Materials A cross-sectional study consisting of 1,013 mothers of children between the ages four to 36 months who visited the immunization clinics at the Community Health Centres in Ife Central and Ife East Local Government Areas. Data was analyzed using STATA (Intercooled release 9) for Windows. Results A total of 765 mothers (75.5%) reported systemic signs and symptoms in their children. Fever (51.8%), diarrhea (12.5%), and vomiting (2.9%) were the most prevalent symptoms and signs reported. Teething problems were reported by 60% of mothers from a high socioeconomic class, as well as 76.7% and 77.9% from middle and low socioeconomic classes, respectively. Interestingly, 65.5% of mothers believed teething should be accompanied with systemic signs and symptoms such as fever (42.1%), diarrhea (13.9%), and vomiting (0.6%). No significant difference was noted between breastfeeding status, gender of the child, and reported systemic signs and symptoms noticed by the mothers. Conclusion Most mothers in the study reported signs and symptoms adduced to teething in their children irrespective of their beliefs. Fever ranked highest of the signs and symptoms reported. Mothers of children from the high socioeconomic class reported fewer teething symptoms. Breastfeeding status and gender of the child had no effect on teething problems in the children studied. Clinical Significance Most signs and symptoms adduced to teething by parents may actually be due to underlying infections. Thus, there is a need to rule out occult infection during the tooth eruption period. Citation Oziegbe EO, Folayan MO, Adekoya-Sofowora CA, Esan TA, Owotade FJ. Teething Problems and Parental Beliefs in Nigeria. J Contemp Dent Pract 2009 July; (10)4:075-082.


2020 ◽  
Author(s):  
Richa Verma

The gastrointestinal system anomalies in the newborn infants are not uncommon and are due to either embryogenesis defects or intrauterine vascular accidents resulting in a compromise of fetal blood circulation to specific system organs. The symptoms generally present within first 1–2 days of life and are mostly referable to intestinal obstruction, manifesting as vomiting, feeding difficulty and distension of abdomen. Other defects may have distinct signs and symptoms and variable time of onset. Some defects may be diagnosed antenatally during prenatal maternal care. The investigations include radiography, magnetic resonance imaging and ultrasound and in a majority of cases clinical presentation and plain radiography may provide adequate diagnostic information. The outcomes of surgical repair are variable and depend upon the original pathological defect. Here, the common anomalies are described with their clinical presentation, surgical repair techniques and outcomes.


Author(s):  
Abhishek Abhishek ◽  
Michael Doherty

Osteoarthritis (OA), the commonest arthropathy, targets specific joints e.g. the knees, hips, interphalangeal joints, and first carpometacarpal joints. Most patients develop symptoms in their middle or older age. Usage-related (’mechanical’) joint pain, short-lived morning stiffness, and locomotor restriction are the common presenting symptoms. Pain at extremes of movement and joint line tenderness may be present in early disease. Crepitus, bony enlargement, and reduced range of movement suggest more severe OA. Advanced OA is characterized by rest pain, night pain, muscle wasting, and deformity. Notably, symptoms and signs of inflammation are absent or only modest, although mild-moderate effusions are not uncommon at the knee. OA may be diagnosed on clinical grounds alone in the at-risk age group, in the presence of typical symptoms and signs. Radiographic changes of OA are commonly asymptomatic. In general there is poor correlation between symptoms, signs, radiographic changes, and disability in OA, and due care should be used to differentiate the ’disease OA’ from the ’illness OA’. More inflammatory symptoms and signs suggest coexistence of calcium crystal deposition. Evaluation of people with OA should include targeted assessment for treatable comorbidities such as depression and obesity that compound disability from OA.


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