scholarly journals Evaluation of Semen Quality in Type 2 Diabetes Mellitus Sudanese Patients Compared to Non-Diabetic Subjects

2018 ◽  
Vol 8 (1) ◽  
pp. 20-25
Author(s):  
Negwan E. Ibrahim ◽  
Mohammed Rida ◽  
AbdElkarim A. Abdrabo

Background: Diabetes leads to metabolic abnormalities. These abnormalities produce problems in a variety of organ systems such as ophthalmopathies, neuropathies, nephropathies, and vasculopathies. Infertility is common in diabetic patients, caused by abnormal semen. Objectives: This study was conducted to check semen quality in diabetic Sudanese patients. Method: This is a retrospective cross-sectional designed study. The data were collected in a period from January 2015 to February 2017. A total of 600 individuals was included, 300 with type 2 diabetes mellitus and 300 apparently healthy as a non-diabetic. Semen analysis was performed according to WHO criteria. Results: Significant lower results were found in diabetic patients compared to non diabetic regarding the following parameters: volume of ejaculation (p = 0.047), percent motility (p = 0.001), percent normal morphology (p = 0.000), while there was no difference in the sperm count between diabetic and non-diabetic subjects. Conclusion: Semen of types 2 diabetes mellitus patients is of low volume, abnormal motility and morphology compared to non-diabetic subjects.

Author(s):  
Anil Shrinivasrao Joshi ◽  
Chandrakant Gunaji Lahane ◽  
Akshay Arvind Kashid

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">To study the prevalence of silent myocardial ischaemia in asymptomatic patients with type 2 DM</span>.</p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">The present study was conducted in the Govt. Medical College and Hospital Aurangabad. During December 2012 to November 2014 with 50 patients. It was two year cross sectional study with the patients of asymptomatic type 2 diabetes mellitus without clinical and electrocardiographic evidence of coronary artery disease. </span></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">12 (24%) out of 50 subjects had positive TMT. It correlated with years of duration of diabetes (9 positive TMT cases with duration of diabetes more than 10 years). 5 (25%) out of 20 had serum cholesterol levels &gt;240, Number of positive TMT were higher in patients with LDL &gt;160 [5 (25%) out of 20]</span>.</p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">Diabetic patients are at very high risk for cardiovascular morbidity and mortality. Early detection of IHD is very important so that pharmacological therapy, which may improve outcome, can be established. Tread mill exercise TMT being a non-invasive test with high safety, has an important role in early detection of IHD. It is recommended that TMT should be a part of routine management in asymptomatic patients with type II DM. </span></p>


Author(s):  
VENKATESAN S. ◽  
SUSILA S. ◽  
SUTHANTHIRAN S. ◽  
MADHUSUDHAN S. ◽  
PAARI N.

Objective: To identify and prevent the vulnerable prediabetic population becoming diabetic patients in the future using the Indian Diabetic Risk Score (IDRS) and to evaluate the performance of the IDRS questionnaire for detecting prediabetes and predicting the risk of Type 2 Diabetes Mellitus in Chidambaram rural Indian population. Methods: A cross-sectional descriptive study was carried out among patients attending a master health check-up of RMMCH hospital located at Chidambaram. The IDRS was calculated by using four simple measures of age, family history of diabetes, physical activity, and waist measurement. The relevant blood test, like Fasting plasma glucose (FBS), Glycated hemoglobin (HbA1C) test, were observed for identifying prediabetes. Subjects were classified as Normoglycemic, prediabetics, and diabetics based on the questionnaire and diagnostic criteria of the Indian Council of Medical Research (ICMR) guidelines. Results: In the study, sensitivity and specificity of IDRS score were found to be 84.21% and 63.4% respectively for detecting prediabetes in community with the positive predictive value of 51.6% and negative predictive value of 89.6% and prevalence of prediabetes in the Chidambaram rural population is 31.6% among the 60 participants. Conclusion: The Indian diabetic risk score questionnaire designed by Ma­dras diabetic research federation is a useful screening tool to identify unknown type 2 diabetes mellitus. The question­naire is a reliable, valuable, and easy to use screening tool which can be used in a primary care setup. 


2017 ◽  
Vol 70 (2) ◽  
pp. 265-270 ◽  
Author(s):  
José Cláudio Garcia Lira Neto ◽  
Mayra de Almeida Xavier ◽  
José Wicto Pereira Borges ◽  
Márcio Flávio Moura de Araújo ◽  
Marta Maria Coelho Damasceno ◽  
...  

ABSTRACT Objective: to identify the prevalence of Metabolic Syndrome and its components in a population of patients with type 2 Diabetes Mellitus. Method: a cross-sectional study was conducted with 201 diabetic patients. A descriptive analysis and Chi-square and Fisher's exact tests ( p <0.05) were performed. Results: the majority of participants were females and overweight, with a mean age of 63.1 years and a low level of education, and categorized as physically inactive. Of all individuals investigated, 50.7% were diagnosed with Metabolic Syndrome and 92% had at least one of the syndrome components with values beyond those recommended. Conclusion: it is essential to take preventive actions and develop studies that help to identify the factors associated with this syndrome.


2019 ◽  
Vol 6 (6) ◽  
pp. 1906
Author(s):  
Mahesh Dave ◽  
Hazari Lal Saini ◽  
Ankit Gupta ◽  
Jitendra Singh Choudhary ◽  
Aniruddha Burli

Background: Diabetes mellitus is an endocrine disorder which involves multiple organ systems and leads to significant morbidity and mortality. Diabetes mellitus has been defined as “A metabolic syndrome characterized by chronic hyperglycemia and disturbance of carbohydrate, fat and protein metabolism associated with absolute or relative deficiency in insulin secretion and or insulin action”. Thyroid diseases are also a common endocrinopathy seen in the adult population. Thyroid hormones are intimately involved in cellular metabolism. The present work is a modest attempt to study the prevalence of thyroid disorders in patients with type 2 diabetes mellitus.Methods: The study was carried out in total 108 diabetic patients without known thyroid disorder admitted in various Medical wards of R.N.T. Medical college and attached group of hospitals, Udaipur. It was a cross Sectional study done over a period of 10 months. Results: In the present study, 13% of patients with type 2 diabetes mellitus had abnormal thyroid profile. Out of which the most common presentation was sub clinical hypothyroidism found in 9.25% followed by1.9% had overt hypothyroidism and 1.9% had sub clinical hyperthyroidism. In persons with abnormal thyroid profile 85.7% were females and 14.3% were males which was statistically significant.Conclusions: Prevalence of thyroid dysfunction is common among T2DM patients and is higher in females than in males. There is no significant correlation between thyroid dysfunction and age, diabetes control, family history, type of treatment and HbA1c level in diabetic patients.


Author(s):  
SARASWATI PRADIPTA ◽  
HERI WIBOWO ◽  
DANTE SAKSONO HARBUWONO ◽  
EKOWATI RAHAJENG ◽  
RAHMA AYU LARASATI ◽  
...  

Objective: Type 2 diabetes mellitus (T2DM) patients tend to have abnormal lipid profiles, explaining the association between elevated cholesterol andtriglyceride levels in diabetic patients and coronary heart disease. This study aims to evaluate how the common risk factors for dyslipidemia affectthe lipid profile of diabetic patients and to determine which factors can be used as predictors for the occurrence of dyslipidemia in T2DM patients.Methods: A total of 238 diabetic patients (63 male and 175 female; age: 31–70 years) were enrolled in this cross-sectional study. All of them hadundergone regular examinations in cohort studies on risk factors for non-communicable diseases conducted by the Ministry of Health in Bogorbetween December 2017 and January 2018.Results: The result found that age differences did not affect lipid profile levels, and the females had higher mean values of body mass index (p<0.001),total cholesterol (TC) (p<0.05), and high-density lipoprotein (HDL) (p<0.001) than the males. The most common occurrences of dyslipidemia werehigh TC level (57.1%), followed by high low-density lipoprotein (LDL) level (47.1%), high triglyceride level (37.4%), and low HDL level (16.4%). Beingoverweight was found to be the best predictor of dyslipidemia.Conclusion: The results of this study suggest that in T2DM patients, sex affects TC and HDL levels, whereas age does not exert a significant effect onthe lipid profiles. In addition, poor glycemic control, hypertension, and obesity may serve as predictors of dyslipidemia in T2DM patients.


2020 ◽  
Vol 7 (4) ◽  
pp. 554
Author(s):  
Ali Akbar P. ◽  
Santosh R. Goudar ◽  
Prabha Adhikari ◽  
Ibrahim Masoodi ◽  
Sydney Dsouza

Background: There is paucity of data regarding the relationship between the severity of left ventricular dysfunction and renal function impairment in diabetic patients. Aims and objectives was to study the relation between eGFR and ejection fraction in type 2 diabetes mellitus of more than 5 years duration.Methods: This cross sectional was carried out from May 2017 to May 2018 at Yenepoya Medical college a tertiary care center in the southern Indian state of Karnataka. The data on 220 diabetic patients were studied. A detailed clinical history physical examination was carried out on the study population as per the approved proforma. Apart from base line investigations, eGFR was calculated using serum creatinine levels. 2D echocardiography was done for the assessment of ventricular function.Results: Out of 220 patients, 138 were men (63%) and 82 were women (37%) and the mean age of the patients was 59.60±11.145 years. The mean duration of diabetes was 10.08±5.28 years. We found a progressive reduction in ejection fraction from 57.74±9.97% to 50.64±14.7 as the eGFR declined from <90 mL/min/1.73m2 to 30 mL/min/1.73m2. There was significant correlation between eGFR and RWMA (p value 0.001) and LVDD (p value 0.029) in this study cohort. Micro/macroalbuminuria was found to be in 55% of patients. Proteinuria had significant correlation with longer duration of diabetes, blood urea, serum creatinine and eGFR.Conclusions: This study found positive clinical correlation between LVEF and eGFR. However, it did not reach significant levels statistically. Further studies may be carried out to confirm the association.


Author(s):  
Vipin Kumar ◽  
Maya Pensiya ◽  
V B Singh

Background: To study the lipid profile in diabetes mellitus in type 2 Diabetes mellitus patients. Methods: This is a cross sectional case control study. 100 patients of type 2 diabetes mellitus and 100 age and sex matched healthy controls were taken. Lipid profile were done in cases and controls using appropriate tests. Results: The fasting blood sugar levels in all the diabetics were significantly higher as compare to control. There was significant difference in mean HDL, Triglycerides level in diabetic and control patients. There was no significant difference in LDL, Cholesterol level in Diabetic and control patients. Conclusion: We concluded that there is a high prevalence of elevated lipid levels among the diabetic patients. Keywords: Diabetes Mellitus -2, Cholesterol, Lipid Profile


2021 ◽  
Vol 10 (1) ◽  
pp. 29-32
Author(s):  
Sanjay Shrestha ◽  
Rajesh Kumar Mandal ◽  
Kijan Maharjan

Background and Aims: Microalbuminuria is an early marker of diabetic nephropathy, which accounts for a significant reduction in life expectancy of diabetic patients. Timely detection of microalbuminuria facilitates appropriate preventive and therapeutic approaches to minimize risks. The aim of this study is to determine the prevalence and association of microalbuminuria with clinical profile and complications of type 2 diabetes mellitus. Methods: This study was a descriptive, cross sectional study involving 100 diabetic subjects between July 2018 to January 2019 at Bir Hospital. Microalbuminuria (mg/dl) was defined as spot urine albumin to creatinine ratio of 30-300 mg/g (Kidney Disease Improving Global Outcomes guidelines) in a single spot urine sample. Statistical analysis was done using Statistical package for the social sciences version 20. Results: Microalbuminuria was found in 35% of the sample and the rate was significantly higher among males (P =0.027). Microalbuminuria was significantly related to Body mass index (P = 0.018), duration of diabetes (P =0.000), retinopathy (P = 0.000) and stroke (P = 0.043). No statistically significant relation was found between microalbuminuria and age (P = 0.366), hypertension (P = 0.208), HbA1c (P = 0.098), dyslipidemia (P = 0.171) and ischemic heart disease (P = 0.651). Conclusions: This study shows high prevalence of microalbuminuria in Nepalese Type 2 diabetes mellitus. Screening for microalbuminuria should be done for all the type 2 diabetes mellitus patients for early detection and management of complications of diabetes mellitus.  


2020 ◽  
Vol 7 (3) ◽  
pp. 497
Author(s):  
Aishhwarrya Umeshchandara G. ◽  
Ravi K.

Background: Anemia is more frequent and severe in diabetics compared to non-diabetic patients. Chronic anemia results in tissue hypoxia, which is known to play a key role in diabetes-associated organ damage. Hence it is important to diagnose and correct anemia in diabetic patients. This study was done to elucidate the effect of glycemic control on haemoglobin levels in patients with type 2 Diabetes mellitus.Methods: The present study is an observational, cross sectional study conducted between November 2017 to May 2019 carried out in hospitals attached to Bangalore Medical college and Research Institute. A sample of 60 patients with Diabetes mellitus were included, out of which 28 were female and 32 were male patients.Results: Study was conducted on 60 patients, the age distribution was between 29yrs to 88yrs with mean age was 56±11yrs. Out of 60 patients 23 patients had anemia. There was slight positive correlation between haemoglobin percentage and HbA1c. But this was not statistically significant.Conclusions: The study concludes that Glycemic control was not found to influence the Haemoglobin levels in patients with Type 2 diabetes mellitus in a significant manner. In subjects with anemia, multiple other issues need to be addressed for improvement in haematocrit value and prevention of complications of diabetes apart from glycemic control.


Sign in / Sign up

Export Citation Format

Share Document