scholarly journals Treatment of Breast Cancer Brain Metastases through a Targeted Nanomolecule Drug Delivery System Based on Dopamine Functionalized Multi-Wall Carbon Nanotubes (MWCNTs) Coated with Nano Graphene Oxide (GO) and Protonated Polyaniline (PANI) in situ During the Polymerization of Aniline Autogenic Nanoparticles for the Delivery of Anti-Cancer Nano Drugs under Synchrotron Radiation

2017 ◽  
Vol 04 (03) ◽  
Author(s):  
Alireza Heidari
Keyword(s):  
Breast Cancer ◽  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Graphene Oxide ◽  
Synchrotron Radiation ◽  
Multi Wall Carbon Nanotubes ◽  
Anti Cancer ◽  
Nano Graphene ◽  
Breast Cancer Brain Metastases

Functionalized Nano-graphene Oxide as Multi-modal Clinic for Effective Drug Delivery

2017 ◽  
Vol 10 (4) ◽  
pp. 3768-3771
Author(s):  
Soumitra Satapathi ◽  
Rutusmita Mishra ◽  
Manisha Chatterjee ◽  
Partha Roy ◽  
Somesh Mohapatra
Keyword(s):  
Drug Delivery ◽  
Graphene Oxide ◽  
Cancer Cell ◽  
High Surface ◽  
High Surface Area ◽  
Cancer Cell Line ◽  
Xrd Analysis ◽  
Graphene Derivatives ◽  
Nano Graphene

Nano-materials based drug delivery modalities to specific organs and tissues has become one of the critical endeavors in pharmaceutical research. Recently, two-dimensional graphene has elicited considerable research interest because of its potential application in drug delivery systems. Here we report, the drug delivery applications of PEGylated nano-graphene oxide (nGO-PEG), complexed with a multiphoton active and anti-cancerous diarylheptanoid drug curcumin. Specifically, graphene-derivatives were used as nanovectors for the delivery of the hydrophobic anticancer drug curcumin due to its high surface area and easy surface functionalization. nGO was synthesized by modified Hummer’s method and confirmed by XRD analysis. The formation of nGO, nGO-PEG and nGO-PEG-Curcumin complex were monitored through UV-vis, IR spectroscopy. MTT assay and AO/EB staining found that nGO-PEG-Curcumin complex afforded highly potent cancer cell killing in vitro with a human breast cancer cell line MCF7.

scholarly journals Synthesis of Poly(methacrylic acid-co-butyl acrylate) Grafted onto Functionalized Carbon Nanotube Nanocomposites for Drug Delivery

Polymers ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 533 ◽  
Author(s):  
Josué A. Torres-Ávalos ◽  
Leonardo R. Cajero-Zul ◽  
Milton Vázquez-Lepe ◽  
Fernando A. López-Dellamary ◽  
Antonio Martínez-Richa ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Drug Delivery ◽  
Methacrylic Acid ◽  
Butyl Acrylate ◽  
Chemical Vapor ◽  
Vis Spectroscopy ◽  
Ir And Raman Spectroscopies ◽  
Ft Ir

Design of a smart drug delivery system is a topic of current interest. Under this perspective, polymer nanocomposites (PNs) of butyl acrylate (BA), methacrylic acid (MAA), and functionalized carbon nanotubes (CNTsf) were synthesized by in situ emulsion polymerization (IEP). Carbon nanotubes were synthesized by chemical vapor deposition (CVD) and purified with steam. Purified CNTs were analyzed by FE-SEM and HR-TEM. CNTsf contain acyl chloride groups attached to their surface. Purified and functionalized CNTs were studied by FT-IR and Raman spectroscopies. The synthesized nanocomposites were studied by XPS, 13C-NMR, and DSC. Anhydride groups link CNTsf to MAA–BA polymeric chains. The potentiality of the prepared nanocomposites, and of their pure polymer matrices to deliver hydrocortisone, was evaluated in vitro by UV–VIS spectroscopy. The relationship between the chemical structure of the synthesized nanocomposites, or their pure polymeric matrices, and their ability to release hydrocortisone was studied by FT-IR spectroscopy. The hydrocortisone release profile of some of the studied nanocomposites is driven by a change in the inter-associated to self-associated hydrogen bonds balance. The CNTsf used to prepare the studied nanocomposites act as hydrocortisone reservoirs.

In Situ Drug Delivery to Breast Cancer-Associated Extracellular Matrix

2018 ◽  
Vol 13 (10) ◽  
pp. 2825-2840 ◽  
Author(s):  
Jodie M. Fleming ◽  
Susan T. Yeyeodu ◽  
Ashley McLaughlin ◽  
Darren Schuman ◽  
Darlene K. Taylor
Keyword(s):  
Breast Cancer ◽  
Drug Delivery ◽  
Extracellular Matrix

Multi-wall carbon nanotubes with nitrogen-containing carbon coating

2013 ◽  
Vol 67 (8) ◽  
Author(s):  
Elena Tomšík ◽  
Zuzana Morávková ◽  
Jaroslav Stejskal ◽  
Miroslava Trchová ◽  
Petr Šálek ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Photoelectron Spectroscopy ◽  
Carbon Coating ◽  
Covalent Bonding ◽  
Inert Atmosphere ◽  
New Materials ◽  
X Ray ◽  
Multi Wall Carbon Nanotubes ◽  
Transmission Electron

AbstractPolyaniline coating was deposited on the surface of multi-wall carbon nanotubes of Russian and Taiwanese origin in situ during the polymerization of aniline. The deposited polyaniline film was subsequently carbonized under an inert atmosphere at various temperatures to produce coaxial coating of the carbon nanotubes with nitrogen-containing carbon. The new materials were investigated by infrared and Raman spectroscopies, which demonstrated the conversion of the polyaniline coating to a carbonized structure. X-ray photoelectron spectroscopy proved that the carbonized overlayer contains nitrogen atoms in various covalent bonding states. Transmission electron microscopy confirmed the coaxial structure of the composites. The Brunauer-Emmett-Teller method was used to estimate the specific surface area, the highest being 272 m2 g−1. The conductivity of 0.9–16 S cm−1 was measured by the four-point method, and it was only a little affected by the carbonization of the polyaniline coating.

Non-covalent modification of graphene oxide nanocomposites with chitosan/dextran and its application in drug delivery

RSC Advances ◽  
2016 ◽  
Vol 6 (11) ◽  
pp. 9328-9337 ◽  
Author(s):  
Meng Xie ◽  
Hailin Lei ◽  
Yufeng Zhang ◽  
Yuanguo Xu ◽  
Song Shen ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Graphene Oxide ◽  
Self Assembly ◽  
Covalent Modification ◽  
Cancer Drug ◽  
Graphene Oxide Nanosheets ◽  
Drug Delivery Application ◽  
Anti Cancer ◽  
Assembly Technique ◽  
Cancer Drug Delivery

Graphene oxide nanosheets non-covalent functionalized with chitosan/dextran was successfully developed via LbL self-assembly technique for anti-cancer drug delivery application.

A comparative study of Ni–Mn layered double hydroxide/carbon composites with different morphologies for supercapacitors

2016 ◽  
Vol 18 (43) ◽  
pp. 30068-30078 ◽  
Author(s):  
M. Li ◽  
F. Liu ◽  
X. B. Zhang ◽  
J. P. Cheng
Keyword(s):  
Carbon Nanotubes ◽  
Graphene Oxide ◽  
Comparative Study ◽  
Layered Double Hydroxide ◽  
Electrode Materials ◽  
Carbon Materials ◽  
Carbon Composites ◽  
Reduced Graphene ◽  
Double Hydroxide

A variety of carbon materials varying from 0D to 2D, i.e. 0D nanoparticles, 1D carbon nanotubes (CNTs) and 2D reduced graphene oxide (rGO) are selected to in situ combine with Ni–Mn layered double hydroxide (LDH) to prepare electrode materials for supercapacitors.

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