scholarly journals Perbedaan Kandungan Energi, Zat Gizi Makro, dan Omega 3 Formula Enteral Blenderized dan Komersial

2021 ◽  
Vol 8 (2) ◽  
pp. 174
Author(s):  
Leny Budhi Harti ◽  
Fuadiyah Nila Kurniasari
Keyword(s):  
Omega 3 ◽  
One Way Anova

<p>Formula enteral blenderized dan komersial merupakan makanan cair yang umum digunakan di Rumah Sakit, akan tetapi pengunaan formula enteral komersial masih sangat terbatas, oleh karena itu untuk memenuhi kebutuhan energi dan zat gizi pasien, maka perlu diberikan formula enteral blenderized Penelitian ini bertujuan untuk mengetahui perbedaan kandungan energi, zat gizi makro, dan omega 3 pada formula enteral blenderized dan komersial. Penelitian ini merupakan Rancang Acak Lengkap (RAL). Jumlah sampel dalam penelitian ini adalah 3 sampel yang terdiri dari formula enteral blenderized, formula komersial merk A dan merk B. Masing-masing sampel tersebut dilakukan pengulangan sebanyak 3 kali. Sampel-sampel tersebut dilakukan analisis energi, zat gizi makro, dan omega 3 sebagai immunonutrient. Perbedaan kadar energi, karbohidrat, dan lemak dianalisis dengan menggunakan One Way ANOVA, sedangkan protein dan omega 3 menggunakan Kruskall-Wallis.Hasil penelitian ini menunjukkan bahwa rata-rata kandungan energi dan karbohidrat formula enteral blenderized  sebesar 80 kkal dan 12,43 gram berbeda bermakna dengan komersial merk A dengan kandungan energi dan karbohidrat sebesar 96,3 kkal dan 15,93 gram (p=0,005 dan p=0,007). Kandungan energi dan karbohidrat formula enteral tersebut juga berbeda bermaknda dengan komersial merk B yang kandungan energi dan karbohidratnya 97 kkal dan 16,15 gram (p=0,004 dan p=0,006), sedangkan kandungan protein (3,22; 3,69; 3,19 gram), lemak (1,92; 1,98; 2,18 gram ), dan omega 3 (0,12; 0,09; dan 0,12%) ketiga kelompok (formula enteral blenderized, komersial merk A, dan B) tidak berbeda bermakna (p=0,97; p=0,33; dan p=0,08).Dari penelitian ini dapat disimpulkan bahwa terdapat perbedaan yang signifikan rata-rata kandungan energi dan karbohidrat antara formula enteral blenderized dan komersial merk A dan B, namun tidak terdapat perbedaan yang signifikan untuk kandungan protein, lemak dan omega 3</p><p><strong> </strong></p><p> </p>

scholarly journals The Effect of Administration of Omega-3 and Vitamin E on the Levels of Reactive Oxygen Species (ROS) and Nitric Oxide (NO) in Preeclampsia White Rats (Rattus Norvegicus)

2021 ◽  
Vol 8 (12) ◽  
pp. 7-15
Author(s):  
Dina Taufia ◽  
Syamel Muhammad ◽  
Arni Amir
Keyword(s):  
Oxidative Stress ◽  
Fatty Acids ◽  
Vitamin E ◽  
Control Group ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Pregnant Rats ◽  
White Rats ◽  
Significant Difference ◽  
One Way Anova

Background: Preeclampsia is a disease with a variety of theories that describe the uncertainty of the pathophysiology. According to the oxidative stress theory, preeclampsia originates from the failure of trophoblast invasion during the implantation process, causing ischemia and placental hypoxia, which in turn causes cell damage, including placental endothelial cell dysfunction. Omega-3 fatty acids and vitamin E have an important role in preventing preeclampsia. Omega-3 fatty acids play an important role in maintaining cell membranes and anti-inflammatory processes. At the same time, vitamin E acts as a fat-soluble antioxidant that can prevent oxidative stress, inhibit proinflammatory cytokines, and protect fatty acids from oxidation. Aim: The purpose of this study was to determine the effect of omega-3 and vitamin E on the level of ROS and NO in pregnant rats with preeclampsia models. Method & Material: This type of research is experimental with Post-Test Only Control Group Design. The sample consisted of 35 pregnant rats, which were divided into five groups. On the 19th day, blood serum was taken to check the levels of ROS and NO. The measuring instrument used is a spectrophotometer with the ELISA method. Data were analyzed using the Shapiro Wilks normality test. After the parametric test was completed, the hypothesis was tested using one-way ANOVA. Results: The average levels of ROS in each group were K- : 121,684 ng/L, K+ : 143,885 ng/L, P1 : 136,250 ng/L, P2 : 132.433 ng/L, and P3 : 122,993 ng/L. The average levels of NO obtained were K-: 29,502 ng/L, K+: 26,053 ng/L, P1: 27,250 ng/L, P2: 27,555 ng/L, and P3: 32,278 ng/L. The results of one-way ANOVA analysis showed that the administration of omega-3 and vitamin E had a significant difference between the control and treatment groups, both at levels of ROS (p=0.001) and levels of NO (p=0.001). Conclusion: The administration of omega-3, vitamin E, and omega-3 plus vitamin E can reduce ROS levels in pregnant rats with preeclampsia models. There is an increase of NO levels only in the administration of omega-3 plus vitamin E. Keywords: [Omega-3, Vitamin E, Oxidative stress, ROS, NO, Preeclampsia].

scholarly journals Kombinasi Suplementasi Omega 3 Dengan Restriksi Kalori Terhadap Penyembuhan Luka Bakar Tikus Sprague Dawley Kajian Pada VEGF dan Re-Epitelisasi

2020 ◽  
Vol 7 (2) ◽  
pp. 432-438
Author(s):  
Doglas Rama Bayu ardha ◽  
Edi Dharmana ◽  
Erik Prabowo
Keyword(s):  
Calorie Restriction ◽  
Cell Injury ◽  
Healing Process ◽  
Control Group ◽  
P Value ◽  
Omega 3 ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Significant Difference ◽  
One Way Anova

Cedera sel yang luas pada luka bakar melepaskan banyak mediator inflamasi. Respon tubuh yang berlebihan pada keadaan tersebut akan memperberat kerusakan sel yang sudah terjadi. Nurtrisi (lemak) yang cukup seperti omega 3 dapat membantu proses penyembuhan luka serta mencegah infeksi pada luka supaya tidak menjadi luka kronis. Maka dari itu peneliti memilih judul penelitian tentang efektifitas kombinasi suplementasi omega 3 dengan restriksi kalori terhadap penyembuhan luka bakar pada tikus Sprague Dawley, ditinjau dari VEGF dan Re-epitelisasi. Untuk mengetahui tingkat efektifitas suplementasi Omega 3 dan retriksi kalori pada penyembuhan luka bakar. Peneliti dalam melakukan penelitian menggunakan metode penelitian eksperimental dengan menggunakan 1 kelas kontrol dan 3 kelas perlakuan tikus Sprague Dawley, yang diinduksi luka bakar kemudian diberi perlakuan, dan diamati secara berkala. Hasil penelitian didapatkan perbedaan yang signifikan antara kelompok kontrol dan kelompok perlakuan yang di uji dengan one way ANOVA mempunyai nilai p = 0,000 (p < 0,05), dan uji Mann-Whitney didapatkan perbedaan yang signifikan antara kelompok perlakuan 1, 2, 3, dan kelompok kontrol p = 0,025; 0,004; 0,004; 0,004; 0,004, nilai p < 0,05. Dan uji Games-Howell ditunjukkan pada kolom rerata ± SD jika memuat huruf yang  berbeda berarti ada perbedaan yang bermakna (p-value <0.05) K1 = 23,3587a ± 0,57556; P1 = 17,1015b ± 2,60108; P2 = 124,1503c ± 15,30168; P3 = 237,5053d ± 0,78263. Kesimpulan yang peneliti dapat bahwa kombinasi suplementasi omega 3 dengan retriksi kalori berpengaruh signifikan terhadap penyembuhan luka bakar pada tikus Sprague Dawley. Kata kunci : Penyembuhan Luka bakar, Sprague Dawley, Omega 3, Retriksi Kalori   Extensive cell injury to burns releases inflammatory mediators. It’s led to excessive body response and cause aggravate cell damage that has already occurred. Adequate nutrients (fat) like omega 3 can help the healing process and prevent infection in wounds to become chronic. Therefore the researchers chose the title of the study of the effectiveness combination omega-3 supplementation with calorie restriction for burns in Sprague Dawley rats, in terms of VEGF and Re-epithelialization. To determine the effectiveness of Omega 3 supplementation and calorie restriction when healing burns. The researchers using experimental research methods with 1 control and 3 training classes of Sprague Dawley mice, which were induced by burns were then observed periodically. The results showed a significant difference between the control group and the treatment group tested by one way ANOVA having a value of p = 0,000 (p <0.05), and the Mann-Whitney test found a significant difference between the treatment groups 1, 2, 3, and the control group p = 0.025; 0.004; 0.004; 0.004; 0.004, p value <0.05. And the Games-Howell test is shown in the mean column ± SD if it contains different letters it means there is a significant difference (p-value <0.05) K1 = 23.3587a ± 0.57556; P1 = 17.1015b ± 2.60108; P2 = 124,1503c ± 15.30168; P3 = 237.5053 d ± 0.78263. The researchers concluded that the combination of omega-3 supplementation with calorie retention had a significant effect on burn healing in Sprague Dawley rats. Keywords: Burn Healing, Sprague Dawley, Omega 3, Calorie Restriction

scholarly journals CLA isomer t10,c12 induce oxidation and apoptosis in 3t3 adipocyte cells in a similar effect as omega-3 linolenic acid and DHA.

2017 ◽  
Vol 7 (2) ◽  
pp. 149 ◽  
Author(s):  
Jon Meadus ◽  
P. Vahmani ◽  
P. Duff ◽  
J.L. Zantinge ◽  
T.D. Turner ◽  
...  
Keyword(s):  
Linolenic Acid ◽  
Lipid Accumulation ◽  
Dairy Products ◽  
Caspase 3 ◽  
Lipid Hydroperoxide ◽  
Oxygen Species ◽  
Omega 3 ◽  
Anti Oxidant ◽  
Student’S T ◽  
One Way Anova

Background: Commercial conjugated linoleic acid (CLA) dietary supplements of contain an equal mixture of the C18:2 isomers, cis-9,trans-11 and trans-10,cis-12. CLA-c9t11 occurs naturally in meat and dairy products as the dominant CLA at 75%, whereas the CLA-t10c12 occurs at <1%. CLA-c9t11 generally promotes lipid accumulation but CLA-t10c12 inhibits lipid accumulation and may promote inflammation.Methods: Purified CLA-c9t11 and CLA-t10c12 were added to 3T3 mature adipocyte cultures at 100uM concentrations and compared with 100uM C18:3(n-3) (α-linolenic acid) and 50uM docosahexaenoic acid (DHA) to study their effect on growth, gene transcription and general oxidation. The results of 4 separate trials were averaged and compared for significance using one way ANOVA and Student’s t-test.Results: C18:3(n-3), DHA and CLA-t10c12 were inhibitory to 3t3 adipose cell growth and caused significant lipid hydro peroxide activity. CLA-t10c12 and c9t11 increased AFABP, FAS and ACOX1 mRNA expression but DHA and C18:3(n-3) decreased the same mRNAs. CLA-c9t11 but not the t10c12 stimulated adipoQ expression even though; c9t11 had only a slightly greater affinity for PPARγ than CLA- t10c12. The expression of the xenobiotic metabolism genes, aldo-keto reductase 1c1  (akr1c1), superoxide dismutase (SOD) and inflammation chemokine secretions of  eotaxin (CCL11), Rantes (CCL5), MIG (CCL9) and MCP-1 were increased by DHA, C18:3(n-3) and CLA-t10c12. This correlated with apoptosis factors, caspase 3, Bcl-2 and BAXs which were partially reduced by co-treatment with lipophilic anti-oxidant α-tocopherol.Conclusions: Based on this evidence, CLA-t10c12 promoted more reactive oxygen species (ROS) than CLAc9t11, in a similar effect as C18:3(n-3) and DHA. In response, cascades of genes are activated to deal with the potentially damaging effects of ROS through detoxification, inflammation or apoptosis.Keywords: CLA-t10c12, CLA-c9t11, gene expression, adipocyte lipid hydroperoxide, DHA,3T3 adipocytes, apoptosis.

Activity Engagement in Cognitive Aging: A Review of the Evidence

2013 ◽  
Vol 23 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Yvonne Rogalski ◽  
Muriel Quintana
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Cognitive Aging ◽  
Social Activity ◽  
Current Evidence ◽  
Omega 3 ◽  
Neuroprotective Effects ◽  
Activity Engagement ◽  
Age Related ◽  
Age Related Cognitive Decline

The population of older adults is rapidly increasing, as is the number and type of products and interventions proposed to prevent or reduce the risk of age-related cognitive decline. Advocacy and prevention are part of the American Speech-Language-Hearing Association’s (ASHA’s) scope of practice documents, and speech-language pathologists must have basic awareness of the evidence contributing to healthy cognitive aging. In this article, we provide a brief overview outlining the evidence on activity engagement and its effects on cognition in older adults. We explore the current evidence around the activities of eating and drinking with a discussion on the potential benefits of omega-3 fatty acids, polyphenols, alcohol, and coffee. We investigate the evidence on the hypothesized neuroprotective effects of social activity, the evidence on computerized cognitive training, and the emerging behavioral and neuroimaging evidence on physical activity. We conclude that actively aging using a combination of several strategies may be our best line of defense against cognitive decline.

Omega-3 Caps Touted as Triglyceride Cutters

2005 ◽  
Vol 36 (9) ◽  
pp. 52
Author(s):  
BRUCE JANCIN
Keyword(s):  
Omega 3

Omega-3 Supplement Fails to Cut Post-MI Events

2009 ◽  
Vol 42 (12) ◽  
pp. 26
Author(s):  
MITCHEL L. ZOLER
Keyword(s):  
Omega 3

Alpkäse – herzhaft gesund oder ein Lifestyle-Produkt?

2005 ◽  
Vol 62 (9) ◽  
pp. 619-624 ◽  
Author(s):  
Hauswirth ◽  
Scheeder ◽  
Beer
Keyword(s):  
Omega 3

Noch im 19. Jahrhundert galten Milch- und Molkenkuren, und insbesondere Alpmilchprodukte, als äußerst gesund, sie wurden in Schweizer Kurhäusern als wichtiges therapeutisches Heilmittel gegen Schwindsucht (Lungentuberkulose) eingesetzt. Seit der Erkenntnis des Zusammenhangs zwischen gesättigten Fetten und Arteriosklerose gelten Milchprodukte wegen des hohen Anteils gesättigter Fette als ungesund und atherogen. Erstaunlicherweise scheinen wiederum die Alpmilchprodukte eine Besonderheit darzustellen: Verschiedene Untersuchungen haben in den letzten Jahren gezeigt, dass sich Milch, Käse und Butter von der Alp in ihrer Fettsäurenzusammensetzung von den im Tal hergestellten Produkten signifikant unterscheiden. So enthält Alpkäse viermal mehr Alphalinolensäure (ALA) und dreimal mehr conjugierte Linolsäure (CLA) als etwa englischer Cheddar, mehr Gesamt-omega-3-FS und eine vorteilhaft tiefe n-6:n-3-Ratio. Sogar Käse von Kühen, die mit Leinsamen zugefüttert werden, enthält weniger ALA und CLA. Die Alpviehhaltung und die Produktion von Alpmilchprodukten birgt ein gesundheitlich interessantes und möglicherweise auch wirtschaftlich wertvolles Potential.

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