scholarly journals The value of the analysis of the urinary stones for studying the features of urolithiasis pathogenesis

2021 ◽  
Vol 9 (3) ◽  
pp. 44-51
Author(s):  
D. G. Lebedev ◽  
V. I. Smirnova ◽  
S. V. Lapin ◽  
O. O. Burlaka ◽  
E. V. Rozengauz ◽  
...  
Keyword(s):  
Kidney Stones ◽  
Preventive Measures ◽  
Recurrent Disease ◽  
Urinary Stones ◽  
Chemical Components ◽  
Chemical Compositions ◽  
Average Amount ◽  
Pathogenic Factors ◽  
Epidemiological Risk ◽  
The Russian Federation

Introduction. Urolithiasis is a multifactorial recurrent disease, unevenly spread throughout the world and characterizedby the formation of urinary stones of various chemical compositions, depending on pathogenesis, etiological, and epidemiological risk factors. Understanding the composition of chemicals and their prevailing ratios can help make decisions about treatment tactics, preventive measures to reduce the risk of recurrence and the prevalence of urolithiasis.Purpose of the study. To assess the distribution of chemical components in urinary stones along with an analysis of their population significance.Materials and methods. The urinary stones were obtained from 2854 patients with urolithiasis. The composition of urinary stones was analyzed by using an infrared spectroscopy method.Results. The predominance of oxalate stones was determined in multicomponent kidney stones (83,7%) and the prevalence of urate stones (54,2%) was revealed in monocomponent kidney stones. Urinary stones with a predominance of oxalates contained significantly fewer impurities (12.4%) than urinary stones with a predominance of urates, phosphates and carbonates with an average amount of impurities >24.0%.Conclusion. The analysis of urinary stones distribution based on pathogenic factors showed that the calcium metabolism disturbances prevail in the population of the Russian Federation (88.0%).

scholarly journals Densitometric density of urinary stones as a predictive factor demonstrating their efficiency of disintegration in treatment of urolithiasis

2019 ◽  
Vol 8 (4) ◽  
pp. 17-24
Author(s):  
Aleksej A. Shevyrin ◽  
Aleksandr I. Strelnikov
Keyword(s):  
Computed Tomography ◽  
Population Data ◽  
Urinary Stones ◽  
Chemical Compositions ◽  
Results Of Treatment ◽  
The Russian Federation ◽  
The Relationship ◽  
Urological Diseases ◽  
Treatment Of Urolithiasis ◽  
Selection Of

Urolithiasis is one of the most common urological diseases, occurring in at least 3% of the human population and 34.2% of the Russian population. Data from the Ministry of Health of the Russian Federation show that in the past 4 years, the incidence of urolithiasis has increased from 405.2 to 460.3 patients per 100,000 population. The purpose of this study was to assess the significance of determining the density of urinary stones via computed tomography, as well as the chemical composition of urinary stones, in order to choose an optimal treatment strategy for patients with urolithiasis. The results of treatment of 108 patients with stones of different localization and sizes were investigated. The patients were subjected to laboratory examination to determine the urinary salt environment; moreover, the levels of electrolytes were examined in blood samples from the patients, and computed tomography densitometry was performed to determine the density of the detected stones. The qualitative chemical compositions of urinary stones in patients with urolithiasis were determined. The density of urinary stones was evaluated by computed tomography densitometry in these patients. The relationship was determined between the chemical compositions of stones and their corresponding densitometric densities. The densitometric density of urinary stones, as determined by computed tomography, can serve as a predictor of the effectiveness of stone disintegration, because it allows selection of the best method to destroy stones for treatment of urolithiasis.

Regulatory Guillotine in the Field of Industrial Safety

2020 ◽  
pp. 22-28
Author(s):  
E.V. Klovach ◽  
◽  
A.S. Pecherkin ◽  
V.K. Shalaev ◽  
V.I. Sidorov ◽  
...  
Keyword(s):  
Russian Federation ◽  
Preventive Measures ◽  
Regulatory System ◽  
Industrial Safety ◽  
State Control ◽  
Regulatory Impact ◽  
The Russian Federation ◽  
The Law ◽  
The Government ◽  
Executive Body

In Russia, the reform of the regulatory guillotine is being implemented in the field of control and supervisory activity. It should result in a new regulatory system formed according to the principles specified in the key federal laws: «On state control (supervision) and municipal control in the Russian Federation» (Law on Control) and «On mandatory requirements in the Russian Federation» (Law on Mandatory Requirements) adopted in August 2020. In the field of industrial safety, this process was launched by the Decree of the Government of the Russian Federation № 1192, which will come into force on January 1, 2021. The main provisions are discussed in the article, which are related to the Law on Control and the Law on Mandatory Requirements. The Law on Control establishes the priority of preventive measures aimed at reducing the risk of causing harm in relation to the control activities, the grounds for carrying out control (supervisory) activities, the types of these activities in the forms of interaction with the controlled person and without such, the procedure for presentation of the results of control (supervisory) activity. The Law on Mandatory Requirements establishes that the provisions of regulatory legal acts should enter into force either from March 1 or September 1, but not earlier than 90 days after their official publication, and their validity period should not exceed 6 years. The drafts of regulatory legal acts developed by the federal executive bodies are subject to regulatory impact assessment. With a view to ensuring systematization of mandatory require ments, their register is kept. The federal executive body prepares a report on the achievement of the goals of mandatory requirements introduction. By January 1, 2021, 10 resolutions of the Government of the Russian Federation, 48 federal norms and rules in the field of industrial safety and 9 other regulatory legal acts of Rostechnadzor should be adopted. The drafts of all the documents are already prepared, some of the acts are completing the process of discussion and approval.

Malignant mesothelioma in the Russian Federation

2020 ◽  
pp. 646-646
Author(s):  
E. V. Kovalevskiy ◽  
S. V. Kashanskiy ◽  
I. M. Tskhomariia
Keyword(s):  
Malignant Mesothelioma ◽  
Russian Federation ◽  
Preventive Measures ◽  
Convincing Evidence ◽  
Malignant Neoplasms ◽  
Asbestos Fibers ◽  
The Russian Federation

One of the malignant neoplasms, which is associated with exposure to only one factor - asbestos fibers, is malignant mesothelioma. At the same time, today there is already convincing evidence of its polyetiology. This indicates the urgent need to expand research in this direction in order to develop targeted preventive measures.

Features of the election of such preventive measure as house arrest in relation to minors

2020 ◽  
Vol 2020 (2) ◽  
pp. 153-157
Author(s):  
Ekaterina Manohina
Keyword(s):  
Supreme Court ◽  
Russian Federation ◽  
Preventive Measures ◽  
Preventive Measure ◽  
Criminal Procedure ◽  
House Arrest ◽  
The Supreme Court ◽  
The Russian Federation ◽  
A Minor

In the article, the author turns to the study of the peculiarities of choosing such a preventive measure as house arrest for minors. Due to the fact that the Code of Criminal Procedure of the Russian Federation does not precisely define cases when a court must elect a house arrest in relation to minors, in practice there are often difficulties in which cases to choose such a preventive measure as detention, and in which house arrest. In the work, the author attempts to determine the essence of such a preventive measure as house arrest and the peculiarities of his election in relation to minors, and also considers the prohibitions and (or) restrictions to which minors cannot be subjected. The positions contained in the resolution of the Plenum of the Supreme Court “On the practice of the application by the courts of legislation on preventive measures in the form of detention, house arrest and bail” are analyzed. The author expresses the opinion that it is inadvisable to choose such a preventive measure as house arrest for minors. Based on the study, the author makes recommendations on the possibility, at the discretion of the court, to make adjustments to the prohibitions and (or) restrictions to which a minor suspect or accused will be subjected to whom such a preventive measure as house arrest is chosen.

Современные методы дезинвазии осадка сточных вод

2020 ◽  
Author(s):  
N. Shakhrai ◽  
N. Dobrynina ◽  
T. Priimak
Keyword(s):  
Preventive Measures ◽  
Wastewater Sludge ◽  
Parasitic Diseases ◽  
Wastewater Disposal ◽  
Judicial Decisions ◽  
Regulatory Documents ◽  
Environmental Objects ◽  
Water And Wastewater ◽  
The Russian Federation ◽  
Rules Set

Организации водопроводно-канализационного хозяйства в рамках технологических процессов водоотведения должны обеспечивать дезинвазию очищенных сточных вод и осадков, образующихся в результате их очистки. В соответствии с пунктом 1.2 СанПиН 3.2.3215-14 Профилактика паразитарных болезней на территории РФ , санитарные правила устанавливают требования к комплексу организационных, санитарно-противоэпидемических (профилактических) мероприятий, проведение которых направлено на предупреждение возникновения и распространения паразитарных заболеваний. Проведена оценка нормативных документов по дезинвазии объектов окружающей среды, а также решений по судебным делам в части ее проведения. Выявлены разногласия в документах по проведению дезинвазии, в связи с чем направлены обращения в различные организации с предложением гармонизировать правила с целью исключения разночтений. Изучены индустриальные методы дезинвазии осадка сточных вод. Показано, что происходит необоснованное навязывание препарата Бингсти .Within the frames of the wastewater disposal processes water and wastewater utilities shall provide for the disinvasion of effluents and wastewater sludge generated in the process of wastewater treatment. In accordance with paragraph 1.2 of SanPiN 3.2.3215-14 Prevention of parasitic diseases in the territory of the Russian Federation , the sanitary rules set out the requirements for a comprehensive set of organizational, sanitary and anti-epidemic (preventive) measures, that are aimed at preventing the occurrence and spread of parasitic diseases. The assessment of regulatory documents on the disinvasion of environmental objects, as well as judicial decisions regarding its implementation, was carried out. Controversies were revealed in the regulatory documents, and appeals were sent to various organizations with a proposal to harmonize the rules in order to exclude discrepancies. Industrial methods for disinvasion of wastewater sludge were studied. It is shown that there is an unreasonable aggressive selling of Bingsti ineffective product.

scholarly journals Evaluations of Surface PM10 Concentration and Chemical Compositions in MERRA-2 Aerosol Reanalysis over Central and Eastern China

2021 ◽  
Vol 13 (7) ◽  
pp. 1317
Author(s):  
Xiaodan Ma ◽  
Peng Yan ◽  
Tianliang Zhao ◽  
Xiaofang Jia ◽  
Jian Jiao ◽  
...  
Keyword(s):  
Eastern China ◽  
Mainland China ◽  
Chemical Components ◽  
Chemical Compositions ◽  
Observation Data ◽  
Causative Factors ◽  
Routine Sampling ◽  
Aerosol Compositions ◽  
Modern Era

The chemical composition dataset of Aerosol Reanalysis of NASA’s Modern-Era Retrospective Analysis for Research and Application, version 2 (MERRAero) has not been thoroughly evaluated with observation data in mainland China due to the lack of long-term chemical components data. Using the 5-year data of PM10 mass concentrations and chemical compositions obtained from the routine sampling measurements at the World Meteorological Organization the Global Atmosphere Watch Programme regional background stations, Jing Sha (JS) and Lin’An (LA), in central and eastern China, we comprehensively evaluate the surface PM10 concentrations and chemical compositions such as sulfate (SO42−), organic carbon (OC) and black carbon (BC) derived from MERRAero. Overall, the concentrations of PM10, SO42−, OC and BC from the MERRAero agreed well with the measurements, despite a slight and consistent overestimation of BC concentrations and a moderate and persistent underestimation of PM10 concentrations throughout the study period. The MERRAero reanalysis of aerosol compositions performs better during the summertime than wintertime. By considering the nitrate particles in PM10 reconstruction, MERRAero performance can be significantly improved. The unreasonable seasonal variations of PM10 chemical compositions at station LA by MERRAero could be causative factors for the larger MERRAero discrepancies during 2016–2017 than the period of 2011–2013.

Is it possible to build an effective program to promote the health and well-being of employees in the workplace in the Russia?

2021 ◽  
pp. 46-56
Author(s):  
Ivan Aleksandrovich Rybakov
Keyword(s):  
Risk Factors ◽  
Russian Federation ◽  
Preventive Measures ◽  
Scientific Evidence ◽  
Well Being ◽  
Ministry Of Health ◽  
Comprehensive Health ◽  
Effective Program ◽  
The Russian Federation ◽  
Health And Well Being

In 2019 The Ministry of Health of the Russian Federation together with experts of the National Research Center of Therapy and Preventive Medicine of the Ministry of Health of the Russian Federation has developed programs to strengthen the health of employees, which include behavioral medicine practices aimed at changing lifestyle and correcting risk factors. Scientific evidence shows the effectiveness of such programs, and new components of programs aimed at improving the well-being of employees can increase the effectiveness of preventive measures. In this article, we will review the domestic and international experience of using comprehensive health and well-being promotion programs to improve the health of employees in Russia.

scholarly journals Insights Into Antioxidant Activities and Anti-Skin-Aging Potential of Callus Extract From Centella Asiatica (L.)

2021 ◽  
Author(s):  
Visarut Buranasudja ◽  
Dolly Rani ◽  
Ashwini Malla ◽  
Khwanlada Kobtrakul ◽  
Sornkanok Vimolmangkang
Keyword(s):  
Oxidative Stress ◽  
Callus Culture ◽  
Antioxidant Activities ◽  
Centella Asiatica ◽  
Skin Aging ◽  
Dermal Fibroblasts ◽  
Bioactive Metabolites ◽  
Chemical Components ◽  
Chemical Compositions ◽  
Scale Production

Abstract Formation of oxidative stress in dermal fibroblasts plays crucial roles in aging processes of skin. The use of phytochemicals that can promote capacity of fibroblasts to combat oxidative stress is an attractive strategy to prevent skin aging and promote skin beauty. Callus culture offers a powerful platform for sustainable, rapid and large-scale production of phytochemicals to serve extensive demands of pharmaceutical and cosmeceutical industries. Here, we demonstrated the application of callus culture of Centella asiatica to produce bioactive metabolites. The 50% ethanolic extract of callus culture has distinctive features of chemical compositions and biological profiles. Results from TLC and HPLC analysis showed that callus extract has unique chemical components, compared with those isolated from authentic plant. Moreover, callus extract possesses promising antioxidant and anti-skin-aging activities. Pre-treatment with callus extract attenuated H2O2-induced-cytotoxicity on human dermal fibroblasts. The results from RT-qPCR clearly suggested that the upregulation of cellular antioxidant enzymes appeared to be major contributor for the protective effects of callus extract against oxidative stress. Moreover, supplementation with callus extract inhibited induction of matrix metalloprotease-9 following H2O2 exposure, suggesting its potential anti-skin-aging activity. Our results demonstrate the potential utility of C. asiatica callus extract as anti-skin-aging agent in cosmeceutical preparations.

scholarly journals Impact of specific prevention on epidemic process of tick-borne viral encephalitis in Siberian Federal District's regions

2019 ◽  
Vol 1 (15) ◽  
pp. 45-48
Author(s):  
S. V. Shirokostup ◽  
I. P. Saldan
Keyword(s):  
Viral Encephalitis ◽  
Preventive Measures ◽  
Federal District ◽  
Epidemiological Survey ◽  
Prevention Measures ◽  
Siberian Federal District ◽  
Tick Bites ◽  
Tick Borne Encephalitis ◽  
Prognostic Criterion ◽  
The Russian Federation

The article presents an assessment of the effectiveness of the effect of specific prevention measures on the incidence of tick-borne viral encephalitis in the population of the regions of the Siberian Federal District. The data on the incidence of Rospotrebnadzor of the Russian Federation and the regions of the Siberian Federal District for 2000–2017 years were used, the reporting of regional health services, the conditions and cause-effect relationships of the incidence of tick-borne encephalitis were assessed in the analysis of epidemiological survey maps of outbreaks. The study found that the analysis of the potential risk of contact with the foci of this infection in the regions of the Siberian Federal District, based on the ranking of regions by the level of population’s appeal for tick bites, can be considered as a prognostic criterion in planning the volume of preventive measures. Vaccination, having a significant impact on reducing morbidity (r = –0.89; p < 0.001) and mortality (r = –0.86; p < 0.001) from this infection, together with seroprophylaxis, can be one of the leading factors in epidemiological forecasting the incidence of tick-borne viral encephalitis in endemic areas.

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