scholarly journals The impact of environmentally unfriendly environment on the circulatory system diseases incidence and prevalence in children of Ukraine

2018 ◽  
Vol 7 (5) ◽  
pp. 229-236
Author(s):  
О. P. Volosovets ◽  
S. P. Kryvopustov ◽  
T. О. Kryuchko ◽  
M. О. Gonchar ◽  
A. E. Abaturov ◽  
...  
2021 ◽  
Vol 102 (6) ◽  
pp. 843-854
Author(s):  
N V Ivanova ◽  
V S Belov ◽  
A I Samarkin ◽  
Z N Tretyakevich ◽  
V M Mikushev ◽  
...  

Aim. To analyze COVID-19 comorbidities and their impact on disease course and the risk for unfavorable outcomes. Methods. This study examined a group of 110 patients aged 32 to 97 who were admitted to the intensive care unit of the Pskov Regional Infectious Diseases Hospital in the period from October 7, 2020 to March 23, 2021. The mean age of patients was 65 years, 51% (56 people) were male. The study recorded age, comorbidities on a binary scale (yes no), course of the disease, the degree of lung injury, hospital length of stay, treatment outcome. The impact of comorbidities on the disease severity and outcomes was assessed by using logistic regression analysis. Results. It was shown that a regional sample of patients showed an increased hospital mortality rate compared with the data of the ACTIV registry (33.5 versus 7.6%). Chronic respiratory diseases in patients with COVID-19 regional cohorts affected the fatal outcome 2.7 times less than those registered in the Russian register. The presence of endocrine and thrombotic circulatory system diseases was generally close to the register. Concomitant cardiovascular diseases in patients of the regional cohort affected the mortality of COVID-19 outcomes two times less (in patients of the region, the risk of mortality increased by 2.066 times) than in the registry. The reliability of the conclusions is confirmed by testing statistical hypotheses and reliability coefficients below 5%. Conclusion. The study shows the statistically significant effect of comorbidities on the COVID-19 outcomes; the specificity of the results related to the sampling characteristics and the regional component.


2019 ◽  
Vol 96 (4) ◽  
pp. 357-362
Author(s):  
S. V. Grebenkov ◽  
L. V. Dovgysha ◽  
E. B. Kolesova ◽  
Ya. M. Sukhova ◽  
S. B. Fedorova ◽  
...  

Introduction. The problem of preservation of the health of drivers is a topical for most of countries. In the process of working, the mentioned group is exposed to a complex of harmful occupational factors, that both leads to an elevated increased risk for health disorders and increases the risk of road accidents. However, in available sources it was not possible to reveal reports devoted to the study of the impact of the labor conditions of drivers on various health indices on the base of the methodology of occupational risk assessment. The aim of the study is to assess the occupational risk for drivers of specialized vehicles on the basis of indices of pathological affection, calculated on the results of periodic medical examinations. Material and Methods. As a core group there were selected truck drivers (n = 1050), as a comparison group - engineering and technical personnel of the enterprise (n = 1220), matched by age and social indices. The assessment of the occupational morbidity rate was carried out on the base of the analysis of fourfold tables with the use of c2 criteria. The assessment of the degree of the occupational dependence was executed with the calculation of risk indices in accordance with the Guidelines for Risk Assessment. Results. In the course of the study there were obtained results showing drivers to suffer most frequently from diseases of eyes (65.4%), circulatory system (46.6%) and digestive system (11.6%). The main reason for the recognition of drivers as unfit to drive vehicles is hypertension at the II stage and above (71.1%). Also, there is noted an increased occupational risk in drivers for such diseases such as hypertension at the I stage (RR=2.2, CI95%=1.8-2.8, EF=54.5%, a high degree of the relationship with the work); encephalopathy of the vascular genesis (RR = 1.6, CI95%=1.1-2.4, EF = 37.5%), moderate degree of the relationship with the work in the age of older 60 years - is very high); dorsopathies at the lumbosacral level (RR=2.9, CI95%=1.6-5.3, EF=65.7%), a high degree of the relationship with the work at the age of over 50 is almost total); sensorineural hearing loss (RR=1.2, CI95%=0.7-2.0, EF=16.4%), a low degree of the relationship with the work over the age of older 60 years - moderate); hyperopia (RR=2.1, CI95%=1.7-2.5, EF=52.4%, a high degree of the relationship with the work), which determines the priority of preventive measures in relation to these diseases. The potential effect of the preventive measures is most pronounced for the circulatory system diseases in total (NNT = 13.6) and hypertensive disease at the I stage (NNT = 10.0).


Author(s):  
Artem Petrovich Pashkov

The number of environmental factors that adversely affect the health of children is growing every year, their combination is different in each territory. It is the child’s body that is most sensitive to changes in environmental conditions, reacting to this with a deterioration in health. Currently, there is a tendency to study the regional characteristics of the interaction of a set of environmental factors with the child’s body. The aim of the work was to identify trends in the primary non-infectious morbidity among children in the Altai Territory, as well as to assess the possible impact of the state of drinking water on the morbidity of children in the region. In the region, an unfavorable tendency was revealed in such groups of nosologies as neoplasms, diseases of the endocrine system, diseases of the circulatory system, diseases of the digestive system, diseases of the genitourinary system, congenital anomalies, and diseases of the respiratory system. The regularity of distribution over the territory of the region of administrative-territorial formations with a high incidence rate was revealed. The analysis of associations of morbidity in children with average annual concentrations of substances polluting the atmospheric air and drinking water showed the presence of reliable correlations in areas of critical and stressful environmental quality. The results obtained indicate the need for a detailed assessment of the influence of environmental factors on the incidence rate of children in the regional aspect, the formation of a database and the development of automated programs capable of predicting the incidence rate in each specific territory. This will improve the efficiency, including the economic, of preventive measures.


2018 ◽  
Vol 97 (11) ◽  
pp. 1005-1010 ◽  
Author(s):  
Yu. A. Rakhmanin ◽  
I. P. Bobrovnitskiii ◽  
Maksim Yu. Yakovlev

Introduction. The article presents scientific and organizational-methodical approaches to the formation and implementation of programs to counter the adverse effects of global climate change on the population health of Russia. According to the results of the study of the relationship between the number of exacerbations of chronic diseases of the circulatory system and the observed meteorological and geomagnetic parameters, the need to develop methods for the determination of the physiological mechanisms of meteorological factors, as well as assessing the individual risks of their influence followed by the use of corrective programs, is shown. Material and Methods. There are presented results of the survey of 168 patients with circulatory system diseases receiving sanatorium-resort treatment. Results. The data obtained showed in most cases (76.8%, 129 people), weather dependence to be manifested in the form of a general deterioration in the well-being of patients. During the physiological examination, the most frequent signs of meteosensitivity were: increased blood pressure - 67.8% (114 people), headache - 41.6% (70 people), sleep disturbance - 47% (79 people), joint pain and muscles - 43.4% (73 people). Discussion. The obtained data allowed us to confirm the prospect of creating a mathematical model for the development of increased meteosensitivity in response to the impact of adverse meteorological factors with the subsequent formation of recommendations for its use in personalized programs of sanatorium-resort treatment of meteo-dependent diseases. Conclusion. The results of the study confirm the need to develop a concept for the development of the scientific direction “environmental medicine”.


2021 ◽  
Vol 20 (3) ◽  
pp. 26-36
Author(s):  
Andrey A. Lobanov ◽  
Sergey V. Andronov ◽  
Anatoliy D. Fesyun ◽  
Andrey P. Rachin ◽  
Irina A. Grishechkina ◽  
...  

There are indications, contraindications and risks of the climatotherapy application. The impact of weather factors on the human body during the period of sanatorium-resort treatment is not only able to trigger the mechanisms of sanogenesis, but also cause a breakdown in adaptation and a deterioration in the course of cardiovascular diseases. According to various domestic sources, pronounced weather sensitivity is observed in 80-85% of patients with common diseases of the circulatory system. Aim. To assess the influence of biotropic weather conditions on the occurrence of exacerbation and progression of meteorological diseases of the circulatory system associated with the passage of sanatorium-resort treatment in another region, in order to draw up a personalized forecast of the exacerbations progression as well as to develop programs for the prevention and treatment of weatherdependent circulatory system diseases. Material and methods. Two series of studies were conducted on a single patient population: a study of adaptation depending on the climatic conditions of the residence region r(n=200) and a retrospective study on symptoms – weather events linkage, the relationship of symptoms with a region of sanatorium-resort treatment (n=148). Designs of retrospective and longitudinal prospective clinical trials were used. To evaluate the presence of weather factors and patient complaints linkage, the method of hierarchical agglomerative clustering was used. The ARIMA moving variable method was used to assess risks and build predictive models. Results. The greatest impact on the well-being of patients with hypertension treated in Sanatorium and Resort Complex «Vulan», a scientific and clinical branch of the National Medical Research Center of Rehabilitation and Balneology, are rapid changes in atmospheric pressure (1.7 points out of 3 maximums possible) and temperature (1.3 points), “magnetic storms” (1.9 points), as well as high atmospheric pressure (1.2 points), the least influence is frost (0.2 points) and snow (0.1 points). Patients with essential hypertension who came to undergo sanatorium-resort treatment in the Southern Federal District (FD) (Gelendzhik) showed pronounced adaptive changes, manifested in an increase in the amplitude of changes in subjective indicators from 3-5 to 10-14 days of treatment. Adaptation of patients who arrived from the Central FD and the Ural FD was distinguished by the onset of the adaptive changes peak on the 3 day and attenuation of adaptive reactions by 10-14th days. In patients coming from the Southern FD, the adaptive reactions were poorly expressed, had no significant peaks and subsided on 10-14th days. Conclusion. The severity of meteopathic reactions depends on the region of the patient’s residence, the region of the sanatoriumresort treatment, the duration of the patient’s staying in the resort area. The questionnaire and the self-control diary developed in the course of the study allow an adequate assessment of the meteorological factors influence on the human body.


Author(s):  
Nina M. Meshchakova ◽  
Marina P. Dyakovich ◽  
Salim F. Shayakhmetov

Introduction.Methanol and its derivatives occupy one of the leading places among the main organic synthesis intermediates in terms of their importance and scale of production. According to experts, by 2027 the global demand for methanol can reach 135 million tons, the annual growth will be about 5.5%. However, there is little information regarding the assessment of working conditions and occupational risks for workers in modern methanol production and its derivatives.The aim of the studyis hygienic assessment of working conditions and the formation of health risks in workers of modern production of methanol and methylamines.Materials and methods.The assessment of the main adverse factors of production is given. When studying the state of health, objective indicators (the results of an in-depth medical examination) and subjective (the results of a quantitative assessment of the risks of the main pathological syndromes associated with health) are considered.Results.According to long-term observations, the concentration of harmful substances in the air of the working area, indicators of labor severity, parameters of physical factors met hygienic requirements, with the exception of industrial noise exceeding the maximum permissible level, as well as labor intensity of 1 degree. The General assessment of working conditions corresponds to the category of harmful 2 degrees (3.2). According to the results of the medical examination and quantitative assessment of the risks of health disorders in workers, the most significant were functional disorders and diseases of the circulatory system. The levels of somatic pathology on the part of the main body systems were significantly higher in apparatchiks compared to the engineering and technical personnel (ETP).Conclusions:In the production of methyl alcohol and methylamines, the main hygienic importance is the impact on workers of the complex of harmful substances of 1-IV hazard classes in low concentrations, increased levels of industrial noise, labor intensity of 1 degree. According to the subjective assessment of health and medical examination, the greatest prevalence of health risks in workers was observed from the circulatory system, and the levels of the revealed somatic pathology were statistically significantly higher in apparatchiks compared with the ETP.


Author(s):  
Zhenzhen Rao ◽  
Junjie Hua ◽  
Ruotong Li ◽  
Yanhong Fu ◽  
Jie Li ◽  
...  

Recent changes in population-based prevalence for circulatory system diseases (CSDs) remain unreported either nationally or locally for China. Data were from the two-round health service household interview survey of Hunan Province, China, in 2013 and 2018. A Rao–Scott chi-square test was performed to examine prevalence differences across socio-demographic variables. The overall age-standardized prevalence of CSDs increased substantially between 2013 and 2018 for inhabitants aged 20 years and older (14.25% vs. 21.25%; adjusted odds ratio (OR) = 1.59, 95% CI: 1.24–2.04). Hypertensive disease was the most prevalent type of CSD, accounting for 87.24% and 83.83% of all CSDs in 2013 and in 2018, respectively. After controlling for other socio-demographic factors, the prevalence of CSDs was significantly higher in 2018 (adjusted OR = 1.40), urban residents (adjusted OR = 1.43), females (adjusted OR = 1.12) and older age groups (adjusted OR = 5.36 for 50–59 years, 9.51 for 60–69 years, 15.19 for 70–79 years, and 12.90 for 80 years and older) than in 2013, rural residents, males and the youngest age group (20–49 years). The recent increase in the overall age-standardized CSD prevalence and the large prevalence disparities across urban/rural residents, sex and age groups merit the attention of policymakers and researchers. Further prevention efforts are needed to curb the increasing tendency and to reduce the prevalence of disparities across socio-demographic groups.


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