Assessment of the impact of the quality of drinking water on the primary morbidity of children in the Altai Territory

Author(s):  
Artem Petrovich Pashkov

The number of environmental factors that adversely affect the health of children is growing every year, their combination is different in each territory. It is the child’s body that is most sensitive to changes in environmental conditions, reacting to this with a deterioration in health. Currently, there is a tendency to study the regional characteristics of the interaction of a set of environmental factors with the child’s body. The aim of the work was to identify trends in the primary non-infectious morbidity among children in the Altai Territory, as well as to assess the possible impact of the state of drinking water on the morbidity of children in the region. In the region, an unfavorable tendency was revealed in such groups of nosologies as neoplasms, diseases of the endocrine system, diseases of the circulatory system, diseases of the digestive system, diseases of the genitourinary system, congenital anomalies, and diseases of the respiratory system. The regularity of distribution over the territory of the region of administrative-territorial formations with a high incidence rate was revealed. The analysis of associations of morbidity in children with average annual concentrations of substances polluting the atmospheric air and drinking water showed the presence of reliable correlations in areas of critical and stressful environmental quality. The results obtained indicate the need for a detailed assessment of the influence of environmental factors on the incidence rate of children in the regional aspect, the formation of a database and the development of automated programs capable of predicting the incidence rate in each specific territory. This will improve the efficiency, including the economic, of preventive measures.

Author(s):  
Lyudmila Mekhantyeva ◽  
Marianna Perfilyeva ◽  
Tatyana Stepanova ◽  
Irina Karateeva ◽  
Alyona Chernigovskaya

The article presents the results of a study on the degree of influence of environmental factors on public health in the Voronezh region. Nowadays, people are often exposed to numerous harmful environmental factors that have a negative impact on their health. The main of the leading factors are air pollution and the hygienic condition of drinking water. The analysis of the sanitary-epidemiological situation was carried out and the incidence rate in the territory of the Voronezh region from 2016–2018 was estimated. We also analyzed the data of observation of air pollution, drinking water at observation posts of organizations of Rospotrebnadzor located in the city of Voronezh. As a result of the study, an analysis was made of the environmental situation in more than 30 districts of the Voronezh region. At the same time, the tendency of the incidence rate in these territories was studied. The presence of endemic diseases of certain classes was revealed. The results of the study indicate the leading factors that have a negative impact on the health of the population living in different regions. In conclusion, it was noted that over the past 4 years, the environmental situation in the territory of the Voronezh region has remained unfavorable. The increased content of certain substances in the air and water of the area entails a high incidence rate for specific classes of diseases. The relationship of environmental pollution indicators with the incidence rate of the population of certain areas was also identified and the dependence of the content of certain substances in the air, water and the purity of the manifestation of specific classes of diseases in various parts of the region was established.


2018 ◽  
Vol 7 (5) ◽  
pp. 229-236
Author(s):  
О. P. Volosovets ◽  
S. P. Kryvopustov ◽  
T. О. Kryuchko ◽  
M. О. Gonchar ◽  
A. E. Abaturov ◽  
...  

2011 ◽  
Vol 34 (1) ◽  
pp. 15-26 ◽  
Author(s):  
Behnam Keshavarzi ◽  
Farid Moore ◽  
Ali Najmeddin ◽  
Farah Rahmani ◽  
Ahad Malekzadeh

2021 ◽  
pp. 274-283
Author(s):  
Yu. L. Korsakova ◽  
E. Yu. Loginova ◽  
E. E. Gubar ◽  
T. V. Korotaeva

Introduction. Psoriatic arthritis (PsA) is a chronic immunoinflammatory disease characterised by involvement of the skin, nail plates, joints, spine and entheses in the inflammatory process. The IL-12/IL-23 inhibitor ustekinumab (UST) is increasingly being used in psoriasis (Ps) and PsA.Aim of the study. To analyze patients with PsA who were under inpatient treatment in the V.A. Nasonova Scientific Research Institute of Rheumatology and Radiology and who were prescribed UST during the period from 2018 to 2020.Material and methods. UST was administered to 17 patients with PsA (9 women and 8 men), mean age was 46.4 ± 11.3 years. Duration of PsA course was 11 ± 10.5 years. Patients underwent clinical, laboratory and instrumental examination, BSA and PASI, DAPSA and BASDAI indices were determined.Results. Patients predominantly had widespread Ps (BSA 18.2 ± 15.9%). Erosive arthritis was present in 94.1% of patients, and sacroiliitis was detected in 100% of patients. PsA activity was high (DAPSA = 44.9 ± 20.9, BASDAI = 6.2 ± 1.5).94% of patients had two or more comorbidities. Circulatory system diseases were observed in 82.4% of patients, liver diseases in 29.5%, gastrointestinal diseases in 47%, endocrine system diseases in 17.6%, viral hepatitis C in 23.5%, latent tuberculosis infection in 17.6%, and joint surgery was performed in 11.2% of patients. The clinical example presented in the article demonstrates good tolerability of UST in a patient with PsA with a number of comorbidities and the possibility to increase the dose of UST from 45 to 90 mg in case of ineffective therapy.Conclusions. The safety profile of UST is good, and it can be administered to patients with cardiovascular diseases, obesity, various infections, including latent tuberculosis, etc. 


Author(s):  
Г. В. Степаненков

У статті розглядається вплив якості питної водиПолтавської області на стан здоров'я населення, атакож представлені результати даного досліджен-ня. Отримані результати подані у вигляді наведенихграфіків і обрахованих коефіцієнтів кореляції. Графі-ки наведені як для загальної захворюваності по обла-сті, так і для двох найбільш розповсюджених групзахворювань (хвороби систем кровообігу, хворобикістково-м’язової системи і сполучної тканини). До-ведено, що якість питної води в області суттєвовпливає на стан здоров'я людей. Зроблені відповіднівисновки загального характеру. The influence of drinking water quality on the level of population health in Poltava region is considered, and the results of the research are given. The obtained results are shown in the graphs and calculated correlation coefficients. Graphs are shown both for the total incidence in the area and for two the most common groups of diseases (blood circulatory system diseases, diseases of the musculoskeletal system and connective tissue). It has been proved that the quality of drinking water in the region has a significant effect on human health. Appropriate general conclusions are drawn.


2021 ◽  
Vol 102 (6) ◽  
pp. 843-854
Author(s):  
N V Ivanova ◽  
V S Belov ◽  
A I Samarkin ◽  
Z N Tretyakevich ◽  
V M Mikushev ◽  
...  

Aim. To analyze COVID-19 comorbidities and their impact on disease course and the risk for unfavorable outcomes. Methods. This study examined a group of 110 patients aged 32 to 97 who were admitted to the intensive care unit of the Pskov Regional Infectious Diseases Hospital in the period from October 7, 2020 to March 23, 2021. The mean age of patients was 65 years, 51% (56 people) were male. The study recorded age, comorbidities on a binary scale (yes no), course of the disease, the degree of lung injury, hospital length of stay, treatment outcome. The impact of comorbidities on the disease severity and outcomes was assessed by using logistic regression analysis. Results. It was shown that a regional sample of patients showed an increased hospital mortality rate compared with the data of the ACTIV registry (33.5 versus 7.6%). Chronic respiratory diseases in patients with COVID-19 regional cohorts affected the fatal outcome 2.7 times less than those registered in the Russian register. The presence of endocrine and thrombotic circulatory system diseases was generally close to the register. Concomitant cardiovascular diseases in patients of the regional cohort affected the mortality of COVID-19 outcomes two times less (in patients of the region, the risk of mortality increased by 2.066 times) than in the registry. The reliability of the conclusions is confirmed by testing statistical hypotheses and reliability coefficients below 5%. Conclusion. The study shows the statistically significant effect of comorbidities on the COVID-19 outcomes; the specificity of the results related to the sampling characteristics and the regional component.


The authors carried out sanitary-hygienic assessment of the concentration of organochlorine compounds in drinking water distribution network and morbidity of the population. To analyze the current situation, monitoring data on the con- centrations of chlororganic compounds determined by gas-liquid chromatography and medico-demographic indicators of population health were used according to the official form of statistical reporting No. 12 (ICD 10). The results of 380 tests for the contents of three chlororganic compounds – chloroform, trichlorethylene and carbon tetrachloride – are presented in the article. Morbidity was represented by 10 classes of diseases: diseases of the digestive system, musculoskeletal system and connective tissue, genitourinary system, neoplasm, circulatory system diseases, endocrine system diseases, eating disorders and metabolic disorders, skin and subcutaneous tissue, nervous system, blood and blood-forming organs, respiratory system diseases. A method for assessing the risk of exposure to chemicals in environmental objects for public health is applied. It has been established that in case of chronic oral intake of chlororganic compounds with drinking water, unacceptable levels of non-carcinogenic risk are formed in respect to target organs such as the liver, kidneys, skin and nervous system in adults and children. Nevertheless, the individual carcinogenic risk for children and adults caused by the effects of high concentrations of chlororganic substances, the largest contribution to which belongs to trichlorethylene, today does not exceed the permissible level.


2019 ◽  
Vol 95 (1) ◽  
pp. 14-17
Author(s):  
A. S. Sboev ◽  
Christina V. Romanenko

The article presents the analysis of the impact of drinking water organochlorine compounds on the population health (Perm region). Results of the carcinogenic and non-carcinogenic health risk assessment for population of the city of Perm and the Perm region under the chronic oral exposure of organochlorine compounds in drinking water are presented. Real concentrations of organochlorine compounds in drinking water were determined to be potent of emerging an unacceptable risk of diseases of the digestive system, endocrine system, hormone system, excretory system, central nervous system and the blood system. According to the results of epidemiological studies there was established the statistically significant relation between the consumption of water containing organochlorine compounds and the development of diseases of the digestive system, endocrine system, central nervous system, and excretory system.


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