scholarly journals CORRELATION OF SERUM ALBUMIN AND CREATININE WITH OXIDATIVE STRESS MARKERS IN PATIENTS HAVING NEPHROTIC SYNDROME

2021 ◽  
pp. 20-24
Author(s):  
GLORY S. PARMAR ◽  
KINNARI N. MISTRY ◽  
SISHIR GANG
Keyword(s):  
Oxidative Stress ◽  
Nephrotic Syndrome ◽  
Correlation Analysis ◽  
Serum Albumin ◽  
Oxidative Stress Markers ◽  
Indian Children ◽  
Sod Activity ◽  
Stress Markers ◽  
Treatment And Prevention ◽  
The Relationship

Objective: Children with nephrotic syndrome (NS) have a stressful condition, and oxidative damage may impair their treatment response. This study aims to gain a better understanding of the relationship between oxidative stress and NS to lay the basis for further research into improved diagnostic options, treatment, and prevention of the disease. Methods: We took a blood sample from 100 Indian patients aged 2-14 y. Each patient was tested for oxidative stress. The buege method was used to assess MDA levels in patients. The pyrogallol method was used to measure SOD activity in blood serum, and the jollow method was used to measure glutathione levels. Results: The levels of oxidative stress markers (MDA, SOD, and GSH) were compared between NS patients and the control. SOD and GSH concentrations were significantly decreased in the NS group when compared to the control. In contrast, MDA level was significantly higher in the NS group than in the control. In the correlation analysis, we found that the serum SOD activity was significantly positively correlated with serum albumin and creatinine level in patients with NS. Thus, oxidative stress in children with NS is indicated by reduced antioxidant potential because of low albumin. Therefore, it is thought that oxidative stress is implicated in the development of NS in Indian children. Conclusion: We concluded that oxidative stress was intensified in children with NS due to decreased antioxidant levels caused by hypoalbuminemia.

scholarly journals The subchronic effects of 3,4-methylendioxymethamphetamine on oxidative stress in rat brain

2014 ◽  
Vol 66 (3) ◽  
pp. 1075-1081
Author(s):  
Ivan Simic ◽  
Violeta Iric-Cupic ◽  
Rada Vucic ◽  
Marina Petrovic ◽  
Violeta Mladenovic ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Peroxidation ◽  
Rat Brain ◽  
Wistar Rats ◽  
Superoxide Radical ◽  
Reduced Glutathione ◽  
Oxidative Stress Markers ◽  
Sod Activity ◽  
Stress Markers ◽  
Male Wistar Rats

The aim of the present study was to evaluate the subchronic effects of 3,4-methylenedioxymethamphetamine on several oxidative stress markers: index of lipid peroxidation (ILP), superoxide dismutase (SOD) activity, superoxide radical (O2.-) levels, and reduced glutathione (GSH) levels in the frontal cortex, striatum and hippocampus of the rat. The study included 64 male Wistar rats (200-250g). The animals were treated per os with of 5, 10, or 20 mg/kg of 3,4-methylenedioxymethamphetamine (MDMA) every day for 15 days. The subchronic administration of MDMA resulted in an increase in ILP, SOD and O2.-, and a decrease in GSH, from which we conclude that oxidative stress was induced in rat brain.

scholarly journals Effects of Advanced Age, Pituitary Pars Intermedia Dysfunction and Insulin Dysregulation on Serum Antioxidant Markers in Horses

Antioxidants ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 444
Author(s):  
Agnieszka Żak ◽  
Natalia Siwińska ◽  
Elżbieta Chełmecka ◽  
Barbara Bażanów ◽  
Ewa Romuk ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Sulfhydryl Group ◽  
Study Groups ◽  
Total Serum ◽  
Pars Intermedia ◽  
Oxidative Stress Markers ◽  
Sod Activity ◽  
Stress Markers ◽  
Insulin Dysregulation ◽  
The Impact

The study aims to assess the impact of age, pituitary pars intermedia dysfunction (PPID) and insulin dysregulation (ID) in horses on selected oxidative stress markers. The study includes 32 horses, divided into three groups: “young” adult group (aged 8–16 years old) “geriatric” group (aged 18–24 years old) and the “PPID” group (aged 15–31 years old). The PPID group was further divided into two subgroups: PPID ID+ and PPID ID− based on presence or absence of ID. We measured serum antioxidant stress markers in all horses: total oxidant status (TOS), total antioxidant capacity (TAC), ceruloplasmin (CER), lipofuscin (LPS), malondialdehyde (MDA) and thiols concentrations (containing sulfhydryl group -SH) as well as enzymatic systems: total superoxide dismutase (SOD), cytoplasmic SOD (CuZnSOD), mitochondrial SOD activity (MnSOD). Total serum thiols were significantly lower in the geriatric group and in the PPID group compared to the young group. The MnSOD concentration was higher in the PPID ID+ group compared to the PPID ID−. LPS and MDA concentrations were lower in the PPID ID+ group compared to the PPID ID− group. In the selected study groups of horses, older age, the presence of PPID and ID in the case of PPID had no effect on the studied oxidative stress markers.

The relationship of oxidative stress markers and parameters of myocardial function in a rat model of cardiotoxicity

2014 ◽  
Vol 75 ◽  
pp. S42 ◽  
Author(s):  
Premysl Mladenka ◽  
Tomáš Filipský ◽  
Michal Ríha ◽  
Jaroslava Vávrová ◽  
Magdalena Holecková ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Rat Model ◽  
Myocardial Function ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
Relationship Of ◽  
The Relationship

scholarly journals The relationship between oxidative stress markers and endometrial hyperplasia: A case-control study

2021 ◽  
Vol 18 (4) ◽  
pp. 298-303
Author(s):  
Engin Yıldırım ◽  
Can Türkler ◽  
Ümit Görkem ◽  
Ömer Yavuz Şimşek ◽  
Ercan Yılmaz ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Endometrial Hyperplasia ◽  
Case Control Study ◽  
Case Control ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
The Relationship ◽  
Control Study

Evaluation of the Relationship Between Nasal Septum Deviation and Oxidative Stress Markers

2019 ◽  
Vol 30 (3) ◽  
pp. 851-853 ◽  
Author(s):  
Ufuk Düzenli ◽  
Nazim Bozan ◽  
Yasin Sonkaya ◽  
Yaser Said Çetin ◽  
Halit Demir
Keyword(s):  
Oxidative Stress ◽  
Nasal Septum ◽  
Oxidative Stress Markers ◽  
Septum Deviation ◽  
Stress Markers ◽  
Nasal Septum Deviation ◽  
The Relationship ◽  
And Oxidative Stress

scholarly journals 4-Hydroxy-2-nonenal Statues in Hypertension Patients

2017 ◽  
Author(s):  
Alaa H. Jawad ◽  
Ammal E. Ibrahim ◽  
Ali Hammed ◽  
Zyad Al-Qaisi ◽  
Amamer Redwan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cardiovascular Diseases ◽  
Control Group ◽  
Hypertensive Subject ◽  
Oxidative Stress Markers ◽  
Ideal Weight ◽  
Stress Markers ◽  
Main Factors ◽  
And Control ◽  
The Relationship

The oxidative stress is one of the main cause for cardiovascular diseases  (like Hypertension) also one of the results of these diseases.  This study involved 56 subjects matched ages  and sex divided into two groups; 28 hypertensive subject and 28 healthy subject as control group. The following analysis was done: 4-Hydroxy-2-nonenal(4HNE) and albumin. The results show that there is a significant increase in (4HNE) between patients group and control group. The increase in 4HNE which is a product of lipid peroxidation  is attributed to destruction in body cell caused by due to the increase in stress events. It has been concluded that is important nappy on ideal weight, because obesity considered main factors for heart disease and hardening of the arteries. The aim of this study was to investigate the relationship between of some oxidative stress markers and cardiovascular diseases.

scholarly journals The relationship between pregnancy and oxidative stress markers on patients undergoing ovarian stimulations

2012 ◽  
Vol 29 (10) ◽  
pp. 1083-1089 ◽  
Author(s):  
Abdelmoneim Younis ◽  
Cynthia Clower ◽  
Deanna Nelsen ◽  
William Butler ◽  
Andrew Carvalho ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Oxidative Stress Markers ◽  
Stress Markers ◽  
The Relationship ◽  
And Oxidative Stress
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