scholarly journals A Review on Medicinal Plants of North Eastern Region with Potential Antifertility Activity

2020 ◽  
Vol 8 (3) ◽  
pp. 162-165
Author(s):  
Priyanka Goswami ◽  
Moksood Ahmed Laskar ◽  
Mrinmoy Basak
Keyword(s):  
Adverse Effect ◽  
Oral Contraceptive ◽  
Medicinal Plants ◽  
Eastern Region ◽  
Plant Origin ◽  
Indian Literature ◽  
Contraceptive Agents ◽  
North Eastern ◽  
Medicinal Properties ◽  
Better Than

The increase in population is becoming a comprehensive problem, causing much pressure on economic, social and natural assets. Oral contraceptive agents have improved the rate of infertility but their unusual side effects limit the use. Current antifertility therapy lacks satisfactory success due to this adverse effect; hence, patients are seeking complementary and alternative medicine for anti-fertility action. Ayurveda and other Indian literature mention the use of plants in various human ailments. India has about more than 45000 plant species and among them several thousand are claimed to possess medicinal properties. Researchers conducted in the last few decades on the plants mentioned in ancient literature or used traditionally for anti-fertility action. This review reveals that some plants and their part used having anti-fertility action, which are helpful for researcher to develop new herbal anti-fertility formulations. In the recent years, interest in drugs of plant origin has been progressively increased. The aim of this review is to highlight the work on anti-fertility of plant origin. For women who can't use modern forms of contraception due to adverse effect or other reasons, therefore herbs can offer alternatives and reducing fertility would be better than other contraceptives. This article may help investigators to identify medicinal plants responsible for anti-fertility activity.  

Asthma and medicinal Plants: A Review

2017 ◽  
Vol 4 (4) ◽  
Author(s):  
Abhinav Vashisth ◽  
Ramandeep Singh ◽  
Satinder Kakar
Keyword(s):  
Adverse Effect ◽  
Medicinal Plants ◽  
Alternative Medicine ◽  
Common Disease ◽  
Asthma Therapy ◽  
Industrialized Countries ◽  
Indian Literature ◽  
Antiallergic Activity ◽  
Ancient Times ◽  
Medicinal Properties

Asthma is a common disease that is rising in prevalence worldwide with the highest prevalence in industrialized countries. Asthma affect about 300 million people worldwide and it has been estimated that a further 100 million will be affected by 2025. Since the ancient times, plants have been exemplary sources of medicine. Current asthma therapy lack satisfactory success due to adverse effect, hence patients are seeking complementary and alternative medicine to treat their asthma. Ayurveda and other Indian literature mention the use of plants in various human ailments. India has about 45 000 plant species and among them several thousand are claimed to possess medicinal properties. Researches conducted in the last few decades on the plants mentioned in ancient literature or used traditionally for asthma have shown antiasthmatic, antihistaminic and antiallergic activity. This review reveals that some plants and their extract have antiasthmatic and antiallergic activity.

PRELIMINARY PHYTOCHEMICAL ANALYSIS OF SELECTED MEDICINAL PLANTS OF NORTH EASTERN REGION OF INDIA

2018 ◽  
Vol 7 (4) ◽  
pp. 88-97
Author(s):  
MELAKYRKHU NIANGMIH ◽  
SAMIRAN CHUTIA ◽  
DAS BANYASHREE ◽  
SARKAR BAPI ROY ◽  
DEY BIPLAB KUMAR ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Phytochemical Analysis ◽  
Eastern Region ◽  
North Eastern

In Silico Docking, ADMET and QSAR Study of few Antimalarial Phytoconstituents as Inhibitors of Plasmepsin II of P. falciparum Against Malaria

2020 ◽  
Vol 15 (3) ◽  
pp. 264-273
Author(s):  
Syeda Sabiha Salam ◽  
Pankaj Chetia ◽  
Devid Kardong
Keyword(s):  
Medicinal Plants ◽  
In Silico ◽  
Computational Study ◽  
Binding Energies ◽  
Eastern Region ◽  
Relationship Analysis ◽  
The North ◽  
North Eastern ◽  
Plasmepsin Ii ◽  
Antimalarial Compounds

Background: Malaria is endemic in various parts of India particularly in the North- Eastern states with Plasmodium falciparum-the most prevalent human malaria parasite. Plantderived compounds have always received tremendous importance in the area of drug discovery and development and scientific study of traditional medicinal plants are of great importance to mankind. Objective: The present work deals with the computational study of some antimalarial compounds obtained from a few medicinal plants used by the tribal inhabitants of the North-Eastern region of India for treating malaria. Methods: In silico methodologies were performed to study the ligand-receptor interactions. Target was identified based on the pharmacophore mapping approach. A total of 18 plant-derived compounds were investigated in order to estimate the binding energies of the compounds with their drug target through molecular docking using Autodock 4.2. ADMET filtering for determining the pharmacokinetic properties of the compounds was done using Mobyle@RPBS server. Subsequent Quantitative-Structure Activity Relationship analysis for bioactivity prediction (IC50) of the compounds was done using Easy QSAR 1.0. Results: The docking result identified Salannin to be the most potent Plasmepsin II inhibitor while the QSAR analysis identified Lupeol to have the least IC50 value. Most of the compounds have passed the ADME/Tox filtration. Conclusion: Salannin and Lupeol were found to be the most potent antimalarial compounds that can act as successful inhibitors against Plasmepsin II of P. falciparum. The compounds Salannin and Lupeol are found in Azadirachta indica and Swertia chirata plants respectively, abundantly available in the North-Eastern region of India and used by many inhabiting tribes for the treatment of malaria and its symptoms.

Medicinal Plants

2020 ◽  
pp. 67-90
Author(s):  
Aashaq Hussain Bhat ◽  
Himani Sharma
Keyword(s):  
Adverse Effect ◽  
Free Radicals ◽  
Medicinal Plants ◽  
Adverse Effects ◽  
Natural Resource ◽  
Medicinal Herbs ◽  
The Body ◽  
Natural Source ◽  
Plant Origin ◽  
Novel Drugs

Medicines of plant origin have been used for treating humans and animals without any adverse effects. New medicinal plants are searched to develop more effective and cheaper drugs in place of synthetics drugs. Plants represent a large natural source of compounds that might serve for the development of novel drugs. Currently medicinal herbs are researched for diuretic properties, and several medicinal herbs are used as diuretics. Currently various synthetic medicines are available for this purpose; however, natural resource medicines are still an important choice because of their higher efficiency and better safety. Further, some herbs are also important sources of antioxidants, which protect the body from the effects of free radicals produced in the body. Antioxidants are required by our body due to increase in the likely exposure of the body to harmful pollutants, radiation, UV lights, etc. These have the ability to delay the oxidation, and plant-derived products are of great interest due to the adverse effect of antibiotics.

Medicinal Plants

2022 ◽  
pp. 43-61
Author(s):  
Aashaq Hussain Bhat ◽  
Himani Goyal Sharma
Keyword(s):  
Adverse Effect ◽  
Free Radicals ◽  
Medicinal Plants ◽  
Adverse Effects ◽  
Natural Resource ◽  
Medicinal Herbs ◽  
The Body ◽  
Natural Source ◽  
Plant Origin ◽  
Novel Drugs

Medicines of plant origin have been used for treating humans and animals without any adverse effects. New medicinal plants are searched to develop more effective and cheaper drugs in place of synthetics drugs. Plants represent a large natural source of compounds that might serve for the development of novel drugs. Currently medicinal herbs are researched for diuretic properties, and several medicinal herbs are used as diuretics. Currently various synthetic medicines are available for this purpose; however, natural resource medicines are still an important choice because of their higher efficiency and better safety. Further, some herbs are also important sources of antioxidants, which protect the body from the effects of free radicals produced in the body. Antioxidants are required by our body due to increase in the likely exposure of the body to harmful pollutants, radiation, UV lights, etc. These have the ability to delay the oxidation, and plant-derived products are of great interest due to the adverse effect of antibiotics.

PRELIMINARY PHYTOCHEMICAL ANALYSIS OF SELECTED MEDICINAL PLANTS OF NORTH EASTERN REGION OF INDIA

2018 ◽  
Vol 7 (5) ◽  
pp. 88-97
Author(s):  
MELAKYRKHU NIANGMIH ◽  
SAMIRAN CHUTIA ◽  
DAS BANYASHREE ◽  
SARKAR BAPI ROY ◽  
DEY BIPLAB KUMAR ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Phytochemical Analysis ◽  
Eastern Region ◽  
North Eastern

scholarly journals Antimicrobial and Cytotoxic Properties of Extracts from Plants Traditionally Used in North-East Brazil

2021 ◽  
Vol 16 ◽  
pp. 21-32
Author(s):  
Airin Aschrafi ◽  
Luisa Zupin ◽  
Lívia Maria Batista Vilela ◽  
Carlos André dos Santos Silva ◽  
Ricardo Salas Roldan Filho ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Medicinal Plants ◽  
Human Keratinocytes ◽  
Eastern Region ◽  
Human Pathogens ◽  
Higher Plant ◽  
North East ◽  
Starting Point ◽  
North Eastern

The north-eastern region of Brazil is home to communities of diverse ethnic origins that still depend significantly on folk medicine, with emphasis on plant extracts. The present work aims at investigating medicinal plants used in the traditional medicine of north-eastern Brazil with an assessment of the antimicrobial profile of their extracts. The antimicrobial activity of 12 extracts from 11 plant species from eight higher plant families traditionally used was evaluated against three human pathogens (Staphylococcus aureus, Escherichia coli, Streptococcus pneumoniae) using the Agar Disk Diffusion and Broth Microdilution assays. The cytotoxic effects were evaluated on human keratinocytes. A hydroalcoholic extract from Anadenanthera colubrina presented the most promising in vitro antimicrobial activity against S.aureus associated with low cytotoxicity towards human keratinocytes. The information gathered in the present study represents a starting point for further research aiming at providing scientific evidence to the empirical usage of medicinal plants in traditional practices.

Examining the Kinships System of the Bodo

Think India ◽  
2019 ◽  
Vol 22 (3) ◽  
pp. 186-192
Author(s):  
Dr. Oinam Ranjit Singh ◽  
Dr. Nushar Bargayary
Keyword(s):  
Social Relationships ◽  
Social Cohesion ◽  
Social Relationship ◽  
Vital Role ◽  
Eastern Region ◽  
The North ◽  
Kinship System ◽  
North Eastern ◽  
The World ◽  
The Relationship

The Bodo of the North Eastern region of India have their own kinship system to maintain social relationship since ancient periods. Kinship is the expression of social relationship. Kinship may be defined as connection or relationships between persons based on marriage or blood. In each and every society of the world, social relationship is considered to be the more important than the biological bond. The relationship is not socially recognized, it fall outside the realm of kinship. Since kinship is considered as universal, it plays a vital role in the socialization of individuals and the maintenance of social cohesion of the group. Thus, kinship is considered to be the study of the sum total of these relations. The kinship of the Bodo is bilateral. The kin related through the father is known as Bahagi in Bodo whereas the kin to the mother is called Kurma. The nature of social relationships, the kinship terms, kinship behaviours and prescriptive and proscriptive rules are the important themes of the present study.

Asymptomatic low-density Plasmodium infection during non-transmission season: a community-based cross-sectional study in two districts of North Eastern Region, India

2021 ◽  
Author(s):  
Hari Shankar ◽  
Sobhan Phookan ◽  
Mrigendra Pal Singh ◽  
Ram Suresh Bharti ◽  
Naseem Ahmed ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Diagnostic Tools ◽  
Eastern Region ◽  
Low Density ◽  
Plasmodium Infection ◽  
Sectional Study ◽  
Cross Sectional ◽  
Health Agencies ◽  
North Eastern ◽  
Asymptomatic Infections

Abstract Background Malaria elimination requires targeting asymptomatic and low-density Plasmodium infections that largely remain undetected. Therefore we conducted a cross-sectional study to estimate the burden of asymptomatic and low-density Plasmodium infection using conventional and molecular diagnostics. Methods A total of 9118 participants, irrespective of age and sex, were screened for malaria using rapid diagnostic tests (RDTs), microscopy and polymerase chain reaction. Results Among the participants, 707 presented with symptoms and 8411 without symptoms, of which Plasmodium was present in 15.6% (110/707) and 8.1% (681/8411), respectively. Low-density infection was found in 5.1% (145/2818) of participants and 8327 of 9118 were Plasmodium negative. Endemicity was propotional to asymptomatic infections (high endemicity 11.1% [404/3633] vs low endemicity 5.8% [277/4778]; odds ratio [OR] 2.0 [95% confidence interval {CI} 1.7 to 2.4]) but inversely related to low-density infection (high endemicity 3.7% [57/1545] vs low endemicity 6.9% [88/1273]; OR 1.9 [95% CI 1.4 to 2.7]). The spleen rate in children 2–9 y of age was 17.9% (602/3368) and the enlarged spleen index was 1.6. Children between 8 and 14 y showed higher odds for asymptomatic (adjusted OR [aOR] 1.75 [95% CI 1.4 to 2.2]) and low-density infections (aOR 0.63 [95% CI 0.4 to 1.0)] than adults. Conclusions The prevalence of asymptomatic and low-density Plasmodium infection undermines the usefulness of standard diagnostic tools used by health agencies. This necessitates deploying molecular tools in areas where malaria microscopy/RDTs indicate a dearth of infection.

scholarly journals Bioactivity of Medicinal Plants and Extracts

Biology ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 634
Author(s):  
Francisco Les ◽  
Guillermo Cásedas ◽  
Víctor López
Keyword(s):  
Medicinal Plants ◽  
Bioactive Compounds ◽  
Medicinal Properties

Nature is an inexhaustible source of bioactive compounds and products with interesting medicinal properties and technological applications [...]

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