scholarly journals Ekstraksi dan Uji Stabilitas Zat Warna Alami dari Bayam Merah (Alternanthera amoena Voss)

KOVALEN ◽  
2020 ◽  
Vol 6 (3) ◽  
pp. 212-217
Author(s):  
Khairuddin ◽  
Joy Noldy Baciang ◽  
Indriani ◽  
Nov Irmawati Inda
Keyword(s):  
Sun Exposure ◽  
Natural Dye ◽  
Natural Dyes ◽  
Stability Test ◽  
Stability Testing ◽  
Effect Of Ph ◽  
Color Degradation ◽  
The Stability ◽  
Better Than

Research on the extraction and stability test of natural dye from red spinach (Alternanthera amoena Voss) has been carried out. This study aims to determine the effect of pH and length of sun exposure on the stability of the dye from red spinach. Extraction using the maceration method with ethanol solvent and measurement using a UV-Vis spectrophotometer. Stability testing is carried out at pH 2-5 and sun exposure for 1-4 hours using a dark and light container. The results obtained, at pH 2 and pH 3, anthocyanins were more stable, compared to pH 4 and 5 which had greater color degradation. In exposure to sunlight, dark containers with a degradation percentage of 31.70% were better than clear containers with a percentage of 48.78%. Keywords: Anthocyanin, red spinach, natural dyes stability.

Stability Testing of Pharmaceutical Products

2021 ◽  
pp. 317-328
Author(s):  
Yashpal Singh Chauhan ◽  
Ravi Nex ◽  
Ghanshyam Sevak ◽  
Mahendra Singh Rathore
Keyword(s):  
Pharmaceutical Products ◽  
Test Methods ◽  
Pharmaceutical Product ◽  
Stability Test ◽  
World Health ◽  
Stability Testing ◽  
Container Closure ◽  
The Stability ◽  
Main Components ◽  
Health Organization

Stability studies must be carried out according to the guidelines provided by the International Conference of Harmonization, World Health Organization, and other agencies in a scheduled manner. The pharmaceutical product’s stability can be defined as the ability, within its physical, chemical, microbiological, toxicology, protective, and informational requirements of a particular formulation in a specific container-closure system. It also guarantees that the performance, safety, and efficacy are maintained throughout the shelf life of any pharmaceutical product which is considered as pre-requisite for acceptance and approval. Different stability test methods have originated with the need for constant monitoring of drugs and products for their quality and purity. In this review, we have included the types of stability of drugs substances, the relevance of different methods used to test the stability of the pharmaceutical product, guidelines issued to test the stability of pharmaceuticals, stability testing protocols which describes the main components of a well-controlled and regulated stability test and other aspects of stability.

scholarly journals Finding the Additives Incorporation Moment in Hybrid Natural Pigments Synthesis to Improve Bioresin Properties

Coatings ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 34 ◽  
Author(s):  
Bàrbara Micó-Vicent ◽  
Jorge Jordán ◽  
Esther Perales ◽  
Francisco Miguel Martínez-Verdú ◽  
Francisco Cases
Keyword(s):  
Antibacterial Properties ◽  
Statistical Design ◽  
Natural Dye ◽  
Natural Dyes ◽  
Uv Aging ◽  
Natural Pigments ◽  
Dye Applications ◽  
The Stability ◽  
Taguchi Designs ◽  
Β Carotene

Interest in applications of natural dye applications has increased because of their antibacterial properties and the possibility of extracting them from nature and residues. Using nanoclays as hosts to reinforce natural dye properties has been successfully demonstrated. However, no one has attempted to optimize the polymer matrix and hybrid pigment properties at the same time to ensure the best final properties for bio-composite applications. Using a statistical design for experiments, we propose the best combination of modifiers with the best nanoclay as the host of three natural dyes: chlorophyll, β-carotene, and betanine. Using the L9 Taguchi designs, we learned both the influence of the nanoclay structure, and the addition moment of surfactant, mordant salt, and silane modifiers. FTIR, XRD, DTG, integration sphere spectrophotometer, and UV-aging tests were used to characterize the hybrid pigments and epoxy bioresin composites. The degradation temperatures of the three natural dyes rose and the reinforcement of the stability of three natural dyes to UV–Vis radiation exposure was demonstrated, which avoided the migration of these dyes from bioresin to wet ribbing. Optimal results were obtained with hydrotalcite clay (calcined or not) by using surfactant and mordant before the natural dye, and before or after silane.

scholarly journals Enhancement stability and color fastness of natural dye: A review

2021 ◽  
Vol 11 (1) ◽  
pp. 548-555
Author(s):  
Catur Harsito ◽  
Aditya Rio Prabowo ◽  
Singgih Dwi Prasetyo ◽  
Zainal Arifin
Keyword(s):  
Biological Effects ◽  
Natural Dye ◽  
Natural Dyes ◽  
Synthetic Dyes ◽  
Spray Dryer ◽  
Color Fastness ◽  
Consumer Awareness ◽  
Red Color ◽  
The Stability

Abstract Consumer awareness of the adverse biological effects of synthetic dyes makes the demand for commercial foods and drinks with natural ingredients increase. The use of natural dyes is increasing and is in demand by consumers in the industrial world. Natural dyes have been used in several sectors such as food, clothing, arts, coatings, and energy. The low stability and brightness of the natural red color are affected by exposure to light, temperature, pH and etc. The co-pigmentation process makes the stability and brightness of natural dyes. The copigmentation method is known that there are two type, liquid and powder. In addition, the combination of copigmentation additives and the correct configuration of the spray dryer process can increase quality color fastness and stability.

scholarly journals A REVIEW ON STABILITY TESTING GUIDELINES OF PHARMACEUTICAL PRODUCTS

2020 ◽  
pp. 3-9
Author(s):  
ZOTHANPUII F ◽  
RAJESH R ◽  
SELVAKUMAR K
Keyword(s):  
Pharmaceutical Products ◽  
Test Methods ◽  
Pharmaceutical Product ◽  
Stability Test ◽  
World Health ◽  
Stability Testing ◽  
Container Closure ◽  
The Stability ◽  
Main Components ◽  
Health Organization

Stability studies must be carried out according to the guidelines provided by the International Conference of Harmonization, World Health Organization, and other agencies in a scheduled manner. The pharmaceutical product’s stability can be defined as the ability, within its physical, chemical, microbiological, toxicology, protective, and informational requirements of a particular formulation in a specific container-closure system. It also guarantees that the performance, safety, and efficacy are maintained throughout the shelf life of any pharmaceutical product which is considered as pre-requisite for acceptance and approval. Different stability test methods have originated with the need for constant monitoring of drugs and products for their quality and purity. In this review, we have included the types of stability of drugs substances, the relevance of different methods used to test the stability of the pharmaceutical product, guidelines issued to test the stability of pharmaceuticals, stability testing protocols which describes the main components of a well-controlled and regulated stability test and other aspects of stability.

scholarly journals Effects of pH and Storage Time on the Stability of Papaya and Carrot Extracts

2019 ◽  
Vol 1 (1) ◽  
pp. 25
Author(s):  
Juliana Juliana ◽  
Renny Indrawati ◽  
Leny Yuliati
Keyword(s):  
Color Difference ◽  
Alkaline Condition ◽  
Natural Pigments ◽  
Treatment Conditions ◽  
Effects Of Ph ◽  
Color Degradation ◽  
The Stability ◽  
And Storage ◽  
Freeze Dryer ◽  
Better Than

Papaya and carrot are rich in natural pigments, especially b-carotene. Unfortunately, in most cases, natural pigments are less stable than the synthetic ones when they are put in a variety of treatment conditions, such as pH. In this work, the stability of the papaya and carrot extracts were evaluated in various pH, which ranges of 1-10 for 7 days. The extracts were obtained by a slow juicer, followed by encapsulation and drying by a freeze dryer. The extracts were then dispersed in buffer solutions and the chroma and color difference (DE) values were calculated from the obtained lightness (L*), redness (a*), and yellowness (b*). The results showed that carrot extract was better than the papaya extract in terms of chroma values. It was also shown that both extracts were not stable under acidic condition, but more stable in neutral to alkaline condition. The acid condition facilitated the cleavage of the conjugated bonds in the b-carotene, which in turn caused the color degradation in the papaya and carrot extracts.

scholarly journals Pengaruh pH Dan Suhu Terhadap Stabilitas Antosianin Dari Ekstrak Kulit Ubi Jalar Ungu (Ipomoea Batatas (L.) Lam.)

2018 ◽  
Vol 2 (2) ◽  
pp. 33-41
Author(s):  
Sandra Tri juli Fendri
Keyword(s):  
Temperature Variation ◽  
Sweet Potato ◽  
Ipomoea Batatas ◽  
Room Temperature ◽  
Analysis Data ◽  
Stability Test ◽  
Color Degradation ◽  
Anthocyanin Stability ◽  
The Stability ◽  
Influence Of Ph

The aim of this research is to knowing about the stability of anthocyanin dye against the influence of pH and temperature, and also degradation of color from purple sweet potato’s peel extracts. The process of sweet potato extraction was done by maceration using ethanol 96%. Anthocyanin stability test was performed on the pH, and variation of pH are 1, 3, 5, 7 and 9. While, temperature variation that used are room temperature, 40°C, 60°C, 80°C and 100°C. To know the absorbance value for color degradation of anthocyanin was measured using a UV-Vis spectrophotometer at 528 nm wavelength maximum. The results of analysis data statistic by using (ANOVA) two way advanced to Duncan test (SPSS 17.0) in stability of pH and temperature are showed that samples more stabile at pH 1 than pH 3 and 5 because there are significant value. The result of % color degradation from pH sample 1, 3 and 5 respectively are 1,47% ; 49,63%  and 52,32%.

PHYTOCHEMICAL CHARACTERIZATION AND TANNIN STABILITY TEST FROM KLUWEK (Pangium edule Reinw)

2019 ◽  
Vol 1 (02) ◽  
pp. 44-49
Author(s):  
Siti Warnasih ◽  
Uswatun Hasanah
Keyword(s):  
Secondary Metabolite ◽  
Uv Light ◽  
Heating Temperature ◽  
Natural Dye ◽  
Stability Test ◽  
Tannin Content ◽  
The Stability ◽  
And Storage ◽  
Duration Of Heating ◽  
Uv Rays

One of the herbs that can be used as a source of natural dye is the kluwek which is brown. This study aims to determine the type of secondary metabolite compounds producing color, and to determine the stability of tannin in various conditions such as pH, oxidizing, UV rays, heating temperature, and storage using UV-Vis spectrophotometry method. This research includes preparation of kluwek, extraction with acetone:water (7:3) with maceration method, phytochemical test (tannin, flavonoid, carotenoid, and anthocyanin) and total tannins, and tannin stability test on various pH, oxidizing, UV rays, temperature and duration of heating, and storage using the UV-Vis spectrophotometry method. The results obtained are kluwek extract containing tannin, flavonoid, carotenoid, and anthocyanin compounds, and total tannins 2.80%. Based on the tannin content, kluwek extract stable at pH 6-7, heating 60-80 oC, and storage up to 9 days at temperature 27 C, and kluwek extract unstable when contact with 1% H2O2, UV light, and if kept at cold temperature (10 ?C).

scholarly journals Dispersion of Carbon Nanotubes with “Green” Detergents

Molecules ◽  
2021 ◽  
Vol 26 (10) ◽  
pp. 2908
Author(s):  
Kazuo Umemura ◽  
Ryo Hamano ◽  
Hiroaki Komatsu ◽  
Takashi Ikuno ◽  
Eko Siswoyo
Keyword(s):  
Carbon Nanotubes ◽  
Sodium Dodecyl ◽  
Detergent Solution ◽  
Absorbance Spectroscopy ◽  
Fundamental Research ◽  
The Stability ◽  
Single Walled Cnts ◽  
Better Than ◽  
Walled Cnts ◽  
Cnt Suspensions

Solubilization of carbon nanotubes (CNTs) is a fundamental technique for the use of CNTs and their conjugates as nanodevices and nanobiodevices. In this work, we demonstrate the preparation of CNT suspensions with “green” detergents made from coconuts and bamboo as fundamental research in CNT nanotechnology. Single-walled CNTs (SWNTs) with a few carboxylic acid groups (3–5%) and pristine multi-walled CNTs (MWNTs) were mixed in each detergent solution and sonicated with a bath-type sonicator. The prepared suspensions were characterized using absorbance spectroscopy, scanning electron microscopy, and Raman spectroscopy. Among the eight combinations of CNTs and detergents (two types of CNTs and four detergents, including sodium dodecyl sulfate (SDS) as the standard), SWNTs/MWNTs were well dispersed in all combinations except the combination of the MWNTs and the bamboo detergent. The stability of the suspensions prepared with coconut detergents was better than that prepared with SDS. Because the efficiency of the bamboo detergents against the MWNTs differed significantly from that against the SWNTs, the natural detergent might be useful for separating CNTs. Our results revealed that the use of the “green” detergents had the advantage of dispersing CNTs as well as SDS.

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