scholarly journals Effect of acute exercise on serum growth hormone and fatty acid levels in elite male water polo players

2014 ◽  
Vol 66 (1) ◽  
pp. 355-361
Author(s):  
Marina Djelic ◽  
Sanja Mazic ◽  
Jasna Tepsic ◽  
D. Nesic ◽  
Biljana Lazovic ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Fatty Acid ◽  
Acute Exercise ◽  
Treadmill Running ◽  
Control Group ◽  
Serum Growth Hormone ◽  
Water Polo ◽  
Baseline Levels ◽  
Incremental Protocol ◽  
Serum Gh

The aim of study was to estimate the effect of acute exercise on serum growth hormone (GH) and fatty acid (FFA) levels in elite water polo players. Twelve male water polo players (20.50 ? 2.02 years) and eleven non-athletic male subjects (20.55 ? 1.04 years) participated in this study. In order to determine GH and FFA responses to acute exercise, a treadmill-running test was performed following an incremental protocol. Pre-exercise blood samples for both athletes and non-athletes were taken at 9 AM. Post-exercise samples were taken immediately after and 30 min after the treadmill running test. Water polo players had significantly lower baseline values of serum GH concentration compared to controls, whereas serum FFA concentration was significantly higher in water polo players compared to controls (p<0.01; p<0.05, respectively). In both groups, concentration of GH was significantly higher immediately after and after the 30-min of recovery compared to baseline levels (p<0.05). In water polo players, the concentration of FFA was significantly decreased immediately after and after the 30-min of recovery compared to baseline levels (p<0.05). No significant response to maximal exercise test was observed in the control group for serum FFA concentration. Our research indicates that acute exercise resulted in a significant increase in serum GH and reduction in fatty acid levels in elite water polo players.

scholarly journals Serum Growth Hormone and Glucose Levels in Acute Exercise and in the Recovery Period in Athletes

2006 ◽  
Vol 6 (2) ◽  
pp. 82-85 ◽  
Author(s):  
Elma Kučukalić-Selimović ◽  
Almira Hadžović-Džuvo ◽  
Emina Nakaš-Ićindić ◽  
Zdenka Dražeta
Keyword(s):  
Growth Hormone ◽  
Acute Exercise ◽  
Recovery Period ◽  
Metabolic Effects ◽  
Work Intensity ◽  
Serum Growth Hormone ◽  
Glucose Levels ◽  
Serum Gh ◽  
Insulin Like Activity

Growth hormone exerts several metabolic effects, including effects on proteins, fats and carbohydrates. Among the many metabolic activities of GH, two contradictory actions were described: acute and early insulin-like activity and chronic and late anti-insulin like activity also called diabetogenic activity. A dramatic increase in plasma concentration of GH was found during endurance exercise, but its role during exercise is not well known. According to its metabolic effects a possible role of growth hormone may be in maintenance of glucose level during exercise. The aim of this study was to analyze dynamics of changes in GH and glucose levels during acute workload and in the recovery period, in a group of well trained athletes. All the subjects exercised for 30 minutes on cycle ergometer in sitting position (work intensity 50% of VO2 max, RPM 60/min). Serum GH concentrations were measured by IRMA (immunoradiometric assays) method in blood samples obtained at rest and 6-min intervals during exercise, and 15-min intervals during recovery period. Serum glucose levels were determined by standard enzymatic method glucose oxidase (GOD PAP) at the same intervals. There were no correlations between serum GH and glucose levels either during exercise or in the recovery period. There were no differences between glucose levels during exercise, so we can not exclude possible role of GH in glucose concentration maintenance.

scholarly journals No Influence of Body Composition on Serum Growth Hormone Response to Acute Dynamic Exercise

2006 ◽  
Vol 6 (3) ◽  
pp. 68-72
Author(s):  
Emina Nakaš-Ićindić ◽  
Almira Hadžović ◽  
Elma Kučukalić-Selimović ◽  
Nesina Avdagić ◽  
Asija Zaćiragić
Keyword(s):  
Growth Hormone ◽  
Body Composition ◽  
Body Mass ◽  
Acute Exercise ◽  
Hormone Response ◽  
Serum Growth Hormone ◽  
Physical Effort ◽  
Total Body Mass ◽  
Total Body ◽  
Serum Gh

Physical effort is a strong physiological stimulus that provokes an increase in blood growth hormone (GH) concentration. Interactions between GH and body composition are very complex. Seven athletes and seven age-matched controls completed a single 30-min bout of upright cycling exercise (5 % of VO(2max).) in order to estimate the influence of body composition on serum GH concentration during exercise. The serum GH concentration was measured in blood samples by standard immunoradiometric (IRMA) method. Anthropometric measurements were used for the calculation of body composition. There were no significant differences in total body mass or body mass index between the groups. The athletes had significantly less fat and higher bone and muscle mass. Serum GH concentration was 2.39 times higher in the athlets versus the control in the period of rest. During acute exercise, the serum GH concentration increased in both groups. No statistically significant differences between the groups in serum GH concentration were found either during the exercise or in the recovery. No correlation between body composition and serum GH concentration was found. Body composition depends on the level of physical activities but if the total body mass is in physiologycal range it does not influence the serum GH response to acute exercise.

scholarly journals Effect of dietary copper sources on performance, gastric ghrelin-RNA expression, and growth hormone concentrations in serum in piglets

2019 ◽  
Vol 97 (10) ◽  
pp. 4242-4247 ◽  
Author(s):  
Ricardo Gonzalez-Esquerra ◽  
Raquel B Araujo ◽  
Douglas Haese ◽  
Joao L Kill ◽  
Anderson F Cunha ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Copper Chloride ◽  
Block Design ◽  
Control Diet ◽  
Phase 1 ◽  
Serum Levels ◽  
Control Group ◽  
Feed Conversion ◽  
Growth Promoters ◽  
Serum Growth Hormone

Abstract Two performance studies were conducted to investigate the effects of 3 different sources of Cu on production parameters of piglets. A total of 256 piglets weaned at 24 ± 2 d were randomly allocated into 4 treatments with 10 or 8 replicates per treatment of 4 or 3 piglets per pen in Exp. 1 and 2, respectively. The experimental period was divided into 3 feeding phases: Phase 1 (24 to 35 d), Phase 2 (36 to 49 d), and Phase 3 (50 to 70 d). Treatments included a Control group (fed 10 mg/kg of Cu from CuSO4), a group fed 160 mg/kg of either CuSO4 (CuSO4-160) or tri-basic copper chloride (TBCC), and a group fed Cu methionine hydroxy analogue chelated (Cu-MHAC) at 150, 80, and 50 mg/kg in Phases 1, 2, and 3, respectively. The methionine value of Cu-MHAC was accounted during diet formulation to achieve the same levels of methionine across treatments. Phases 1 and 2 diets contained 2,200 and 1,500 ppm of ZnO, respectively; and antibiotics were used as growth promoters. Performance parameters were analyzed as completely randomized block design, in which each experiment was considered as a block. In trial 2, blood serum and mucosal samples, from the fundic region of the stomach, were collected from 1 piglet per replicate at day 70 and tested for serum growth hormone levels (GH) and ghrelin mRNA expression, respectively. The contrast between Cu-MHAC vs. CuSO4-160 + TBCC showed that piglets fed Cu-MHAC exhibited better feed conversion ratio (FCR) in all feeding phases compared with feeding inorganic Cu (P < 0.05). Overall, feeding Cu-MHAC improved body weight (BW), BW gain, feed intake (FI), and FCR vs. Control diet fed piglets; yet, it improved BW and FCR vs. TBCC fed piglets, and improved BW, BW gain, and FI vs. CuSO4-160 fed piglets (P < 0.05). Feeding TBCC promoted similar performance than feeding CuSO4-160, regardless of age (P > 0.05). Both ghrelin expression and growth hormone serum levels were significantly increased by feeding Cu-MHAC vs. Control diet fed animals (P < 0.01). Feeding CuSO4-160 upregulated ghrelin expression vs. Control (P < 0.01) while GH serum levels and ghrelin expression did no change by feeding TBCC compared with Control diet fed animals (P > 0.05). It was concluded that feeding Cu-MHAC at the levels tested herein can improve growth performance of piglets beyond feeding 160 ppm of either CuSO4 or TBCC, which may be partially explained by the increased expression of ghrelin and GH serum levels.

Chronic resistance training in women potentiates growth hormone in vivo bioactivity: characterization of molecular mass variants

2006 ◽  
Vol 291 (6) ◽  
pp. E1177-E1187 ◽  
Author(s):  
William J. Kraemer ◽  
Bradley C. Nindl ◽  
James O. Marx ◽  
Lincoln A. Gotshalk ◽  
Jill A. Bush ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Resistance Training ◽  
Resistance Exercise ◽  
Molecular Mass ◽  
Acute Exercise ◽  
Control Group ◽  
Detection Systems ◽  
Molecular Variants ◽  
Exercise Induced

This investigation determined the influence of acute and chronic resistance exercise on responses of growth hormone (GH) molecular variants in women. Seventy-four healthy young women (23 ± 3 yr, 167 ± 7 cm, 63.8 ± 9.3 kg, 26.3 ± 4.0% body fat) performed an acute bout of resistance exercise (6 sets of 10 repetition maximum squat). Blood samples were obtained pre- and postexercise. Resulting plasma was fractionated by molecular mass ( fraction A, >60 kDa; fraction B, 30–60 kDa; and fraction C, <30 kDa) using chromatography. Fractionated and unfractionated (UF) plasma was then assayed for GH using three different detection systems (monoclonal immunoassay, polyclonal immunoassay, and rat tibial line in vivo bioassay). Subjects were then matched and randomly placed into one of four resistance exercise training groups or a control group for 24 wk. All experimental procedures were repeated on completion of the 24-wk resistance training programs. After acute exercise, immunoassays showed consistent increases in UF GH samples and fractions B and C; increases in fraction A using immunoassay were seen only in the monoclonal assay. No consistent changes in bioactive GH were found following acute exercise. Conversely, chronic exercise induced no consistent changes in immunoassayable GH of various molecular masses, whereas, in general, bioassayable GH increased. In summary, although acute exercise increased only immunoactive GH, chronic physical training increased the biological activity of circulating GH molecular variants. Increased bioactive GH was observed across all fractions and training regimens, suggesting that chronic resistance exercise increased a spectrum of GH molecules that may be necessary for the multitude of somatogenic and metabolic actions of GH.

Training-induced alterations of the fatty acid profile of rabbit muscles

2002 ◽  
Vol 50 (3) ◽  
pp. 357-364 ◽  
Author(s):  
Éva Szabó ◽  
R. Romvári ◽  
Hedvig Fébel ◽  
Keyword(s):  
Fatty Acid Composition ◽  
Fatty Acid ◽  
Fatty Acid Profile ◽  
Acid Composition ◽  
Vastus Lateralis ◽  
Total Activity ◽  
Treadmill Running ◽  
Control Group ◽  
Daily Routine ◽  
Significant Difference

The present study was designed to investigate whether meat-type rabbits are able to perform treadmill running as a daily routine exercise, and if so, whether the exercise induces specific proportional changes in the fatty acid composition of their muscles. After a four-week training period 8-week-old rabbits were slaughtered and the total activity of plasma lactate dehydrogenase was measured, showing a significant difference between the exercised and control groups (429 ± 126 IU/l vs. 639 ± 203 IU/l). Furthermore the fatty acid composition of m. longissimus dorsi (MLD) and m. vastus lateralis (MVL) was determined by means of gas chromatography. Exercise increased the proportions of oleic acid (C18:1 n-9) in both MLD and MVL as compared to the control group. However, the level of stearic (C18:0) and arachidonic (C20:4 n-6) acids significantly decreased in the MVL after the exercise. Changes in the fatty acid profile resulting from the physically loaded condition were of the same tendency in both muscles, adding that the MVL might have been exposed to the exercise more intensively; alterations there occurred in a more pronounced manner. Based on the inference that the composition of membrane structure was also affected, these alterations may have important consequences on meat quality.

The effects of ovariectomy on meat performance and expression of GH/IGF-I in young goats

2014 ◽  
Vol 94 (4) ◽  
pp. 619-626 ◽  
Author(s):  
Lei Zhang ◽  
Yan-yan Wang ◽  
Ming-zhe Fu ◽  
Guang Li ◽  
Ning An ◽  
...  
Keyword(s):  
Meat Quality ◽  
Production Efficiency ◽  
Biceps Femoris ◽  
Control Group ◽  
Meat Production ◽  
Mrna Levels ◽  
Animal Performance ◽  
Serum Growth Hormone ◽  
Igf I ◽  
Serum Gh

Zhang, L., Wang, Y.-y., Fu, M.-z., Li, G., An, N., Li, S.-y. and Zhou, Z.-q. 2014. The effects of ovariectomy on meat performance and expression of GH/IGF-I in young goats. Can. J. Anim. Sci. 94: 619–626. Experiments were carried out to investigate the effects of ovariectomy on meat production efficiency and to explore the expression of GH/IGF-I in young goats. Animal performance, meat quality, levels of serum growth hormone (GH) and insulin-like growth factor 1 (IGF-I), and mRNA levels of three key genes [GH Receptor (GHR), IGF-I and IGF-I Receptor (IGF-IR)] in longissimus dorsi and biceps femoris muscles were measured. The results show that carcass weight, net meat mass, fat weight and loin eye area of ovariectomized goats were higher than those of the controls, and ovariectomized goats lost 0.40 kg of bone weight (P<0.05). There was no statistically valid difference for the color, pH, water-holding capacity, or cooking rate of meat (P>0.05) between the two groups, except for the shear value, which was significantly lower in the Ovx group than in the control group (P<0.05). The results of this research show for the first time a significant trend (P<0.05) for serum GH and IGF-I in the direction of increasing in ovariectomized goats. Furthermore, the mRNA levels of GHR, IGF-I and IGF-IR in muscle were all up-regulated, except for the IGF-I gene in biceps femoris, by ovariectomy. In summary, ovariectomy showed a beneficial promotion in animal performance, but did not reduce meat quality, and increased serum GH and IGF-I and mRNA expression levels of GHR, IGF-I and IGF-IR in young female goats.

Acute and Chronic Hormonal Responses to Resistance Training Designed to Promote Muscle Hypertrophy

1999 ◽  
Vol 24 (1) ◽  
pp. 96-107 ◽  
Author(s):  
Gary E. Mccall ◽  
William C. Byrnes ◽  
Steven J. Fleck ◽  
Arthur Dickinson ◽  
William J. Kraemer
Keyword(s):  
Growth Hormone ◽  
Resistance Training ◽  
Acute Exercise ◽  
High Volume ◽  
Sex Hormone Binding Globulin ◽  
Control Group ◽  
Type I ◽  
Hormonal Responses ◽  
Serum Hormone ◽  
Exercise Induced

Acute and chronic hormonal responses to resistance training were evaluated in 11 college men who completed 12 weeks (33 sessions) of high volume resistance training. No differences in resting concentrations of growth hormone (GH), insulin-like growth factor-I, testosterone, or sex hormone-binding globulin occurred from pre- and posttraining in the trained vs. nontrained control group. However, cortisol (C) decreased 17% for both groups (p < 0.05). There were no differences in exercise-induced responses between Sessions 10 and 20, with all hormone concentrations increasing (p < 0.05) from pre- at mid- and postexercise session. However, after correction for plasma volume decreases, only C and GH showed differences, with C increased from mid- to postsession (48% 10th: 49% 20th), and GH increased from pre- at mid- and postsession for both sessions 10 (0.16 ± 0.42 pre; 4.77 ± 6.24 mid; 6.26 ± 5.19 post; µg L−1) and 20 (0.33 ± 085 pre; 5.42 ± 9.08 mid; 8.24 ± 7.61 post; µg L−1). Significant correlations (p < 0.05) existed only between absolute mean GH increases from presession and the degree of muscle fiber hypertrophy for type I (r = 0.70 mid, 0.74 post) and type II (r = 0.71 post) fibers. In conclusion, resistance training had no effect on resting serum hormone concentrations, whereas similar acute exercise responses occurred between the 10th and 20th training sessions. Keywords: humans, weight training, growth hormone, IGF-I, testosterone, cortisol

Growth hormone in exercise: comparison of physiological and pharmacological stimuli

1976 ◽  
Vol 41 (4) ◽  
pp. 523-527 ◽  
Author(s):  
J. Sutton ◽  
L. Lazarus
Keyword(s):  
Growth Hormone ◽  
Cycle Ergometer ◽  
Serum Growth Hormone ◽  
Insulin Hypoglycemia ◽  
Arginine Infusion ◽  
Provocative Test ◽  
Gh Secretion ◽  
Ergometer Exercise ◽  
Normal Males ◽  
Serum Gh

This study was designed to compare the serum growth hormone (GH) response with quantified exercise to that obtained with other stimuli. In eight normal males, aged 21–24 yr, we studied the serum GH response to 20 min cycle ergometer exercise at 300, 600, and 900 kpm/min on three separate occasions and compared the results with those found during sleep, insulin hypoglycemia, arginine infusion, and L-DOPA. Exercise at 900 kpm/min and insulin hypoglycemia resulted in the greatest elevations in serum GH which weresignificantly greater than those found with sleep, arginine or L-DOPA. The 20-min exercise at 900 kpm/min represented 75–90% of the subjects' maximal oxygen uptake and is a suitable provocative test for GH secretion. As a screening test for pituitary GH reserve, exercise compares favorably with insulin hypoglycemia and is superior to sleep, arginine, and L-DOPA.

Endurance training enhances BDNF release from the human brain

2010 ◽  
Vol 298 (2) ◽  
pp. R372-R377 ◽  
Author(s):  
Thomas Seifert ◽  
Patrice Brassard ◽  
Mads Wissenberg ◽  
Peter Rasmussen ◽  
Pernille Nordby ◽  
...  
Keyword(s):  
Cerebral Cortex ◽  
Human Brain ◽  
Endurance Training ◽  
Acute Exercise ◽  
Venous Blood ◽  
Treadmill Running ◽  
Controlled Study ◽  
Control Group ◽  
Bdnf Expression ◽  
Blood Samples

The circulating level of brain-derived neurotrophic factor (BDNF) is reduced in patients with major depression and type-2 diabetes. Because acute exercise increases BDNF production in the hippocampus and cerebral cortex, we hypothesized that endurance training would enhance the release of BDNF from the human brain as detected from arterial and internal jugular venous blood samples. In a randomized controlled study, 12 healthy sedentary males carried out 3 mo of endurance training ( n = 7) or served as controls ( n = 5). Before and after the intervention, blood samples were obtained at rest and during exercise. At baseline, the training group (58 ± 106 ng·100 g−1·min−1, means ± SD) and the control group (12 ± 17 ng·100 g−1·min−1) had a similar release of BDNF from the brain at rest. Three months of endurance training enhanced the resting release of BDNF to 206 ± 108 ng·100 g−1·min−1 ( P < 0.05), with no significant change in the control subjects, but there was no training-induced increase in the release of BDNF during exercise. Additionally, eight mice completed a 5-wk treadmill running training protocol that increased the BDNF mRNA expression in the hippocampus (4.5 ± 1.6 vs. 1.4 ± 1.1 mRNA/ssDNA; P < 0.05), but not in the cerebral cortex (4.0 ± 1.4 vs. 4.6 ± 1.4 mRNA/ssDNA) compared with untrained mice. The increased BDNF expression in the hippocampus and the enhanced release of BDNF from the human brain following training suggest that endurance training promotes brain health.

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