The “Three Ages” of Cinema Studies and the Age to Come

PMLA ◽  
2000 ◽  
Vol 115 (3) ◽  
pp. 341-351 ◽  
Author(s):  
Dudley Andrew

The october 1999 job list prepared by the society for cinema studies has just appeared: fifty-one teaching positions involving film. What does it mean that only ten of these are situated in designated film programs, while thirty-six are hosted by departments of literature, primarily English? It means, among other things, that departments of literature are redefining and deregulating themselves. They may have cautiously welcomed film for a half century but hardly at this scale: fifty-one open positions suggest hundreds of positions permanently in place and thousands of students studying this subject each year. The confidence the humanities shows in this field is shared by most of my students, who are younger than cinema studies and must sense it to be, if not august, at least well established, rather as English seemed when I majored in it and assumed it to be as old as England. However, any census of course catalogs reveals cinema's uncertain location and function from campus to campus, posing questions of general expectations and standards—indeed, putting in question the definition of cinema studies. Evidently universities want to offer film. Bravo! But in what manner and for what purpose? What “qualifies” the hundreds of applicants applying for these fifty-one positions? Where did they gain their expertise or self-confidence?

2018 ◽  
Author(s):  
Stacy A. Malaker ◽  
Kayvon Pedram ◽  
Michael J. Ferracane ◽  
Elliot C. Woods ◽  
Jessica Kramer ◽  
...  

<div> <div> <div> <p>Mucins are a class of highly O-glycosylated proteins that are ubiquitously expressed on cellular surfaces and are important for human health, especially in the context of carcinomas. However, the molecular mechanisms by which aberrant mucin structures lead to tumor progression and immune evasion have been slow to come to light, in part because methods for selective mucin degradation are lacking. Here we employ high resolution mass spectrometry, polymer synthesis, and computational peptide docking to demonstrate that a bacterial protease, called StcE, cleaves mucin domains by recognizing a discrete peptide-, glycan-, and secondary structure- based motif. We exploited StcE’s unique properties to map glycosylation sites and structures of purified and recombinant human mucins by mass spectrometry. As well, we found that StcE will digest cancer-associated mucins from cultured cells and from ovarian cancer patient-derived ascites fluid. Finally, using StcE we discovered that Siglec-7, a glyco-immune checkpoint receptor, specifically binds sialomucins as biological ligands, whereas the related Siglec-9 receptor does not. Mucin-specific proteolysis, as exemplified by StcE, is therefore a powerful tool for the study of glycoprotein structure and function and for deorphanizing mucin-binding receptors. </p> </div> </div> </div>


2009 ◽  
Vol 54 (1) ◽  
pp. 69-102
Author(s):  
Robin Rehm

Kasimir Malewitschs suprematistische Hauptwerke ›Schwarzes Quadrat‹, ›Schwarzer Kreis‹ und ›Schwarzes Kreuz‹ von 1915 setzen sich aus schwarzen Formen auf weißem Grund zusammen. Der Typus des Schwarzweißbildes weist überraschende Parallelen zu den bildlichen Wahrnehmungsinstrumenten auf, die vom ausgehenden 18. bis Anfang des 20. Jahrhunderts in den Experimenten der Farbenlehre, physiologischen Optik und Psychologie verwendet worden sind. Die vorliegende Studie untersucht diese Parallelen in drei Schritten: Zunächst erfolgt eine allgemeine Charakterisierung des Schwarzweißbildes mit Hilfe des Kontrastbegriffs von Edmund Husserl. Des weiteren wird die Entstehung und Funktion des schwarzweißen Kontrastbildes in den Wissenschaften des 19. Jahrhunderts typologisch herausgearbeitet. Unter Berücksichtigung des Wissensbegriffs von Max Scheler wird abschließend die Spezifik des Wissens eruiert, das die Schwarzweißbilder sowohl in der Malerei Malewitschs als auch in den genannten Wissenschaften generieren. Malevich’s main Suprematist works, such as ›Black Square‹, ›Black Circle‹, and ›Black Cross‹ from 1915, consist of black shapes on white ground. Surprisingly this series of shapes strongly resembles scientific black-and-white images used for research on colour theory, physiological optics, and psychology throughout the 19th century. This paper examines the parallels between Malevich’s paintings and the scientific drawings in three steps: It first characterizes black-and-white images in general, using Edmund Husserl’s definition of the term ›contrast‹. Secondly, the paper investigates the development and function of black-and-white images as tools of perception in the sciences. It finally discusses the specific knowledge generated through Malevich’s art and through scientific black-and-white images, following Max Scheler’s phenomenological identification of knowledge.


Author(s):  
Benjamin E. Reynolds

The central place of revelation in the Gospel of John and the Gospel’s revelatory telling of the life of Jesus are distinctive features of John when compared with the Synoptic Gospels; yet, when John is compared among the apocalypses, these same features indicate John’s striking affinity with the genre of apocalypse. By paying attention to modern genre theory and making an extensive comparison with the standard definition of “apocalypse,” the Gospel of John reflects similarities with Jewish apocalypses in form, content, and function. Even though the Gospel of John reflects similarities with the genre of apocalypse, John is not an apocalypse, but in genre theory terms, John may be described as a gospel in kind and an apocalypse in mode. John’s narrative of Jesus’s life has been qualified and shaped by the genre of apocalypse, such that it may be called an “apocalyptic” gospel. Understanding the Fourth Gospel as “apocalyptic” Gospel provides an explanation for John’s appeal to Israel’s Scriptures and Mosaic authority. Possible historical reasons for the revelatory narration of Jesus’s life in the Gospel of John may be explained by the Gospel’s relationship with the book of Revelation and the history of reception concerning their writing. An examination of Byzantine iconographic traditions highlights how reception history may offer a possible explanation for reading John as “apocalyptic” Gospel.


Author(s):  
Jessica Brown

This chapter distinguishes between fallibilism and infallibilism by appeal to entailment: infallibilists hold that knowledge that p requires evidence which entails that p; fallibilists deny that. It outlines some of the recent motivations for infallibilism, including the infelicity of concessive knowledge attributions, the threshold problem, closure, and the knowledge norm of practical reasoning. Further, we see how contemporary infallibilists attempt to avoid scepticism by appeal either to a generous conception of evidence or a shifty view of knowledge, such as contextualism. The chapter explains the book’s focus on non-shifty versions of infallibilism which defend a generous conception of evidence. It ends by defending the entailment definition of infallibilism over other potential definitions, and outlining the chapters to come.


Author(s):  
J. Donald Boudreau ◽  
Eric Cassell ◽  
Abraham Fuks

This book reimagines medical education and reconstructs its design. It originates from a reappraisal of the goals of medicine and the nature of the relationship between doctor and patient. The educational blueprint outlined is called the “Physicianship Curriculum” and rests on two linchpins. First is a new definition of sickness: Patients know themselves to be ill when they cannot pursue their purposes and goals in life because of impairments in functioning. This perspective represents a bulwark against medical attention shifting from patients to diseases. The curriculum teaches about patients as functional persons, from their anatomy to their social selves, starting in the first days of the educational program and continuing throughout. Their teaching also rests on the rock-solid grounding of medicine in the sciences and scientific understandings of disease and function. The illness definition and knowledge base together create a foundation for authentic patient-centeredness. Second, the training of physicians depends on and culminates in development of a unique professional identity. This is grounded in the historical evolution of the profession, reaching back to Hippocrates. It leads to reformulation of the educational process as clinical apprenticeships and moral mentorships. “Rebirth” in the title suggests that critical ingredients of medical education have previously been articulated. The book argues that the apprenticeship model, as experienced, enriched, taught, and exemplified by William Osler, constitutes a time-honored foundation. Osler’s “natural method of teaching the subject of medicine” is a precursor to the Physicianship Curriculum.


2021 ◽  
Vol 61 (3) ◽  
pp. 320-340
Author(s):  
Kate Rousmaniere

AbstractThis essay examines the history of what is commonly called the town-gown relationship in American college towns in the six decades after the Second World War. A time of considerable expansion of higher education enrollment and function, the period also marks an increasing detachment of higher education institutions from their local communities. Once closely tied by university offices that advised the bulk of their students in off-campus housing, those bonds between town and gown began to come apart in the 1970s, due primarily to legal and economic factors that restricted higher education institutions’ outreach. Given the importance of off-campus life to college students, over half of whom have historically lived off campus, the essay argues for increased research on college towns in the history of higher education.


Antioxidants ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 173
Author(s):  
Desirée Bartolini ◽  
Rita Marinelli ◽  
Danilo Giusepponi ◽  
Roberta Galarini ◽  
Carolina Barola ◽  
...  

The metabolism of α-tocopherol (α-TOH, vitamin E) shows marked interindividual variability, which may influence the response to nutritional and therapeutic interventions with this vitamin. Recently, new metabolomics protocols have fostered the possibility to explore such variability for the different metabolites of α-TOH so far identified in human blood, i.e., the “vitamin E metabolome”, some of which have been reported to promote important biological functions. Such advances prompt the definition of reference values and degree of interindividual variability for these metabolites at different levels of α-TOH intake. To this end, a one-week oral administration protocol with 800 U RRR-α-TOH/day was performed in 17 healthy volunteers, and α-TOH metabolites were measured in plasma before and at the end of the intervention utilizing a recently validated LC-MS/MS procedure; the expression of two target genes of α-TOH with possible a role in the metabolism and function of this vitamin, namely pregnane X receptor (PXR) and the isoform 4F2 of cytochrome P450 (CYP4F2) was assessed by immunoblot in peripheral blood leukocytes. The levels of enzymatic metabolites showed marked interindividual variability that characteristically increased upon supplementation. With the exception of α-CEHC (carboxy-ethyl-hydroxychroman) and the long-chain metabolites M1 and α-13′OH, such variability was found to interfere with the possibility to utilize them as sensitive indicators of α-TOH intake. On the contrary, the free radical-derived metabolite α-tocopheryl quinone significantly correlated with the post-supplementation levels of α-TOH. The supplementation stimulated PXR, but not CYP4F2, expression of leucocytes, and significant correlations were observed between the baseline levels of α-TOH and both the baseline and post-supplementation levels of PXR. These findings provide original analytical and molecular information regarding the human metabolism of α-TOH and its intrinsic variability, which is worth considering in future nutrigenomics and interventions studies.


Author(s):  
Kate Cowcher

The Pan-African Film and Television Festival of Ouagadougou (FESPACO) was founded in 1969. It began as an intimate week-long gathering of filmmakers and enthusiasts in the capital of what is now Burkina Faso to watch contemporary films made by African filmmakers. At its peak in the 1990s, it attracted hundreds of thousands of spectators, both local and international. Since the 2000s, iterations have been smaller affairs, significantly impacted by both changes of government in Burkina Faso and wider political instability in West Africa, as well as ongoing debates about what films it should be showcasing. Despite such challenges (and with only one exception in the mid-1970s), however, FESPACO has remained a constant on the African continent, faithfully screening films by African and diaspora filmmakers every two years for more than half a century. FESPACO was conceived in the age of decolonization by a group of men and women who are considered to be the pioneers of African cinema, including the Senegalese writer and filmmaker Ousmane Sembène. It was established as the first sub-Saharan showcase of African filmmaking, an emergent and significant field in the era of independence when cinema was prized for its ability to make visible African realities and to (re)constitute national histories eclipsed by colonial rule. The concept of a distinctly “African” cinema was articulated most extensively by filmmaker and scholar Paulin Soumanou Vieyra and referred to films made by Africans, telling African stories, principally for African audiences. For Vieyra, Sembène, and their contemporaries, it was essential to take back control of the art of cinema on the African continent, where it had predominantly been deployed as a colonial tool; FESPACO was conceived as the regular forum for those committed to its development to come together and share their work. Through the course of its development, FESPACO has been confronted with a number of challenges regarding its form and its evolution. Its strong connections with the Burkinabe state have been seen as both a significant factor for its growth and its success, and, particularly in the era of Blaise Compaoré, as a source for concern regarding freedom of expression. Since the turn of the 21st century, questions about where video filmmaking—an industry that has proliferated on the African continent in a manner unprecedented internationally—fits within FESPACO’s definition of cinema have been consistent. The festival has, over the years, been accused of being both outdated and elitist in its commitment to celluloid, but also of straying from its original remit to showcase African stories for African audiences, accusations it has responded to by the creation of new prize categories and requirements for submission. The year 2019 was one of reflection, but many critics felt that after some difficult years the festival was showing signs of rejuvenation. Though it is now one of many film festivals on the continent committed to showcasing African cinema, there remains significant appreciation for the historic status of FESPACO as a preeminent sub-Saharan cultural institution.


Author(s):  
Igor I. Kartashov ◽  
Ivan I. Kartashov

For millennia, mankind has dreamed of creating an artificial creature capable of thinking and acting “like human beings”. These dreams are gradually starting to come true. The trends in the development of modern so-ciety, taking into account the increasing level of its informatization, require the use of new technologies for information processing and assistance in de-cision-making. Expanding the boundaries of the use of artificial intelligence requires not only the establishment of ethical restrictions, but also gives rise to the need to promptly resolve legal problems, including criminal and proce-dural ones. This is primarily due to the emergence and spread of legal expert systems that predict the decision on a particular case, based on a variety of parameters. Based on a comprehensive study, we formulate a definition of artificial intelligence suitable for use in law. It is proposed to understand artificial intelligence as systems capable of interpreting the received data, making optimal decisions on their basis using self-learning (adaptation). The main directions of using artificial intelligence in criminal proceedings are: search and generalization of judicial practice; legal advice; preparation of formalized documents or statistical reports; forecasting court decisions; predictive jurisprudence. Despite the promise of using artificial intelligence, there are a number of problems associated with a low level of reliability in predicting rare events, self-excitation of the system, opacity of the algorithms and architecture used, etc.


2016 ◽  
Vol 19 (1) ◽  
pp. 167-181
Author(s):  
José Eduardo Porcher

Although delusion is one of the central concepts of psychopathology, it stills eludes precise conceptualization. In this paper, I present certain basic issues concerning the classification and definition of delusion, as well as its ontological status. By examining these issues, I aim to shed light on the ambiguity of the clinical term ‘delusion’ and its extension, as well as provide clues as to why philosophers are increasingly joining the ranks of psychiatrists, psychologists, and neuroscientists in the effort to come to a comprehensive understanding of delusion.


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