Magnesium deficiency in IDDM related to level of glycosylated hemoglobin

Background: The aim of the study was to compare the hemoglobin levels among normal controls (patients) and patients of TypeII diabetes with HbA1c levels below 7 % & above 7 %.and secondly to identify the undetected cases of anemia in TypeII diabetes. Materials & Methods - 50 patients of type 2 diabetes mellitus with their glycosylated hemoglobin levels less than 7 %, 50 patients of type 2 diabetes mellitus with their glycosylated hemoglobin levels more than 7 % attending the Medicine outpatient department of Subharti Medical College and Hospital will be the subjects for the study.50 age and sex matched controls will be selected randomly from Subharti Medical College and Hospital. Informed written consent will be taken from all the subjects. The study will be conducted from January 2016 to January. Result - We studied 50 cases with HbA1C>7(poor control),50 cases with HbA1C 5.6 to7 (good control) and 50 controls with HbA1C ≤5.6, we observed in cases with HbA1C>7 (poorly control) ,the mean HbA1C is 9.9±2 and mean Hb is 9.8±1.3 as compared to cases with HbA1C 5.6 to 7(good control) where mean HbA1C is 6±0.4 and Hb is 13±0.5,this clearly indicates that in cases HbA1C is more Hb levels are low and when HbA1C is less Hb levels are higher. Conclusion - In the present study we found negative correlation between HbA1c & Hb levels. As the value of HbA1c increases, as in cases of HbA1c >7(poor diabetic control), we found low Hb levels as compared to the cases with HbA1c <7(5.6-7) (good control).

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Glycosylated hemoglobin levels and complications of acute coronary syndromes - A prospective study at tertiary care hospital

Medpusle International Journal of Medicine ◽

10.26611/10219310 ◽

2019 ◽

Vol 9 (3) ◽

pp. 192-195

Author(s):

Abhijeet A Nashte ◽

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Ravindra K Shravasti ◽

Amey S Vaidya ◽

◽

...

Keyword(s):

Prospective Study ◽

Acute Coronary Syndromes ◽

Tertiary Care Hospital ◽

Glycosylated Hemoglobin ◽

Tertiary Care ◽

Care Hospital ◽

Coronary Syndromes ◽

A Prospective Study

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Influence of magnesium deficiency on selected aspects of protein metabolism

10.31274/rtd-180813-2859 ◽

1960 ◽

Author(s):

Evelyn May Cox

Keyword(s):

Protein Metabolism ◽

Magnesium Deficiency

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Faculty Opinions recommendation of Dietary magnesium deficiency alters gut microbiota and leads to depressive-like behaviour.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.725362896.793504466 ◽

2015 ◽

Author(s):

Peter Holzer

Keyword(s):

Gut Microbiota ◽

Magnesium Deficiency ◽

Dietary Magnesium

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Good Glycemic Control for a Low Cardiovascular Risk in Children Suffering from Diabets

Revista de Chimie ◽

10.37358/rc.17.2.5453 ◽

2017 ◽

Vol 68 (2) ◽

pp. 358-361

Author(s):

Camelia Busila ◽

Mariana Cretu Stuparu ◽

Aurel Nechita ◽

Camelia Ana Grigore ◽

Gabriela Balan

Keyword(s):

Glycosylated Hemoglobin ◽

Control Group ◽

Sex Distribution ◽

Good Glycemic Control ◽

Rural And Urban ◽

Lipid Panel ◽

Patients With Diabetes ◽

Kolmogorov Smirnov ◽

Low Cardiovascular Risk

The study is a prospective and operational one, ant its was conducted on 58 patients with diabetes type 1 and 2. The patients sex distribution was homogenious and they come from both rural and urban environment. The statistical analisys was carried out using the programme SPSS 17.0 for Windows. The distribution normality was cheked using the Kolmogorov - Smirnov Z test. he values of glycemia, glycosylated hemoglobin, lipid panel, blood pressure have been measured and compared to the ones belonging to the control group.

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Control of Magnesium Deficiency in Utah 10B Celery Grown on Organic Soil

Soil Science Society of America Journal ◽

10.2136/sssaj1957.03615995002100050018x ◽

1957 ◽

Vol 21 (5) ◽

pp. 528-532 ◽

Cited By ~ 5

Author(s):

K. E. E. Johnson ◽

J. F. Davis ◽

E. J. Benne

Keyword(s):

Magnesium Deficiency ◽

Organic Soil

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TA-65, A Telomerase Activator improves Cardiovascular Markers in Patients with Metabolic Syndrome

Current Pharmaceutical Design ◽

10.2174/1381612824666180316114832 ◽

2018 ◽

Vol 24 (17) ◽

pp. 1905-1911 ◽

Cited By ~ 9

Author(s):

Maria Luz Fernandez ◽

Minu Sara Thomas ◽

Bruno S. Lemos ◽

Diana M. DiMarco ◽

Amanda Missimer ◽

...

Keyword(s):

Oxidative Stress ◽

Metabolic Syndrome ◽

Plasma Lipids ◽

Disease Risk ◽

Glycosylated Hemoglobin ◽

Cardiovascular Disease Risk ◽

Hdl Cholesterol ◽

Double Blind ◽

Tnf Α ◽

Luminex Technology

Background: Telomerase Activator 65 (TA-65), a compound extracted from Astragalus membranaceus has been used in Chinese traditional medicine for extending lifespan. Scarce information exists on the effects of TA-65 on parameters of metabolic syndrome (MetS). Methods: We recruited 40 patients with MetS to determine the effects of TA-65 on dyslipidemias, hypertension, and oxidative stress in this at-risk population. The study was a double-blind, randomized crossover design in which patients were allocated to consume either 16 mg daily of a TA-65 supplement or a placebo for 12 weeks. Following a 3-week washout, participants were allocated to the alternate treatment for an additional 12 weeks. Anthropometric and biological markers were measured at the end of each treatment. Plasma lipids, glucose, CReactive Protein (CRP), liver enzymes, and glycosylated hemoglobin were measured using a Cobas c-111. Inflammatory cytokines were measured by Luminex technology and markers of oxidative stress by the use of spectroscopy. Results: Compared to the placebo period, HDL cholesterol (HDL-C) was higher while body mass index, waist circumference, and the LDL/HDL ratio were lower (p < 0.05) during TA-65 treatment. In addition, plasma tumor necrosis factor-α (TNF-α) was lower during the TA-65 period (p< 0.05). Positive correlations were observed in changes between the placebo and the TA-65 periods in HDL-C and CRP (r = -0.511, p < 0.01), alanine aminotransferase (r = -0.61, p < 0.001) and TNF-α (r = -0.550, p < 0.001) suggesting that the favorable changes observed in HDL were associated with decreases in inflammation. Conclusion: TA-65 improved key markers of cardiovascular disease risk, which were also associated with reductions in inflammation.

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The value of glycosylated hemoglobin in the diagnosis of diabetic retinopathy: a systematic review and Meta-analysis

BMC Endocrine Disorders ◽

10.1186/s12902-021-00737-2 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Bo Zhang ◽

Bingjie Zhang ◽

Zhulin Zhou ◽

Yutong Guo ◽

Dan Wang

Keyword(s):

Diabetic Retinopathy ◽

Likelihood Ratio ◽

Roc Curve ◽

Meta Analysis ◽

Glycosylated Hemoglobin ◽

Positive Likelihood Ratio ◽

Negative Likelihood Ratio ◽

Biomedical Literature ◽

Cochrane Library ◽

Clinical Value

AbstractObjectiveGlycosylated hemoglobin (HbA1c) has obvious clinical value in the diagnosis of diabetes, but the conclusions on the diagnostic value of diabetic retinopathy (DR) are not consistent. This study aims to comprehensively evaluate the accuracy of glycosylated hemoglobin in the diagnosis of diabetic retinopathy through the meta-analysis of diagnostic tests.MethodsCochrane Library, Embase, PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), China Wanfang Database, Chinese Biomedical Literature Database (CBM) were searched until November, 2020. The Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool was used to assess the quality of the included studies. The pooled sensitivity, specificity, positive likelihood ratio (+LR), negative likelihood ratio (-LR), diagnostic odds ratio (DOR) and areas under the receiver operating characteristic (ROC) curve were calculated by Stata 15.0 software.ResultsAfter screening, 18 high-quality papers were included. The results of meta-analysis showed that the combined DOR = 18.19 (95% CI: 10.99–30.11), the sensitivity= 0.81 (95% CI): 0.75 ~ 0.87), specificity = 0.81 (95%CI: 0.72 ~ 0.87), +LR = 4.2 (95%CI: 2.95 ~ 6.00), −LR = 0.23 (95%CI: 0.17 ~ 0.31), and the area under the Summary ROC curve was 0.88 (95%CI: 0.85 ~ 0.90).ConclusionThe overall accuracy of HbA1cC forin diagnosing diabetic retinopathy is good. As it is more stable than blood sugar and is not affected by meals, it may be a suitable indicator for diabetic retinopathy.

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