scholarly journals Single Renal Metastasis From Cervical Cancer

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Youssef Ghannam ◽  
Oussama Elidrissi ◽  
H. Moudlige ◽  
M. Dakir ◽  
A. Debbagh ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Renal Mass ◽  
Local Development ◽  
Treatment Session ◽  
Epidermoid Carcinoma ◽  
Renal Metastasis ◽  
End Of Treatment ◽  
Total Nephrectomy

63-year-old patient, followed for cervical cancer classified 2b; declared cured after a treatment with chemo-radiotherapy and brachytherapy and who presents after 10 months of his last treatment session a fortuitous discovery of a right renal mass The patient subsequently benefited from a right enlarged total nephrectomy whose anatomo study pathology showed the appearance of a secondary epidermoid carcinoma of cervical neo. In our case, there is a single renal metastasis of cervical cancer with no local development and after 10 months from the end of treatment.

Incidental renal masses: Therapeutic management

1992 ◽  
Vol 59 (1_suppl) ◽  
pp. 153-155
Author(s):  
A. Prati ◽  
C. Cantoni ◽  
I. Pieri ◽  
P. Sacchini ◽  
A. Savino ◽  
...  
Keyword(s):  
Renal Mass ◽  
Percutaneous Biopsy ◽  
Imaging Studies ◽  
Benign Lesions ◽  
Renal Masses ◽  
Traditional Treatment ◽  
Radiologic Imaging ◽  
Management Alternatives ◽  
Total Nephrectomy

Evaluation and treatment of incidental renal masses is a problem facing urologists with increasing frequency since radiologic imaging (Echotomography and CT) has become routine. Traditional treatment by total nephrectomy may be unnecessary for small renal cell carcinoma and is often inappropriate for benign, lesions: whereas only observation by periodic follow-up with imaging studies and/or percutaneous biopsy is not always sufficient. So the problem of management alternatives is very important and no universal strategy can be employed. We report our experience with 15 pts with incidental renal mass treated in different ways.

Renal Metastasis from Thyroid Carcinoma 35 years after Detection of the Primary Tumor

2003 ◽  
Vol 89 (1) ◽  
pp. 99-101 ◽  
Author(s):  
Luigi Insabato ◽  
Dolores Di Vizio ◽  
Gaetano De Rosa ◽  
Domenico Prezioso ◽  
Franco Corcione ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Thyroid Carcinoma ◽  
Primary Tumor ◽  
Renal Mass ◽  
Renal Tumor ◽  
Latency Period ◽  
Renal Neoplasms ◽  
Renal Metastasis ◽  
Secondary Tumor ◽  
Long Latency

A case of a solitary, unilateral, large metastatic renal tumor found 35 years after the detection of primary thyroid carcinoma is presented. Renal metastasis from thyroid carcinoma detected during life is extremely rare, and there may be a long latency period before the appearance of a secondary tumor. The possibility of a secondary tumor should always be considered in the differential diagnosis of renal neoplasms, even when the tumor is a large, unilateral, solitary renal mass.

IN SITU EPIDERMOID CARCINOMA OF THE CERVIX AND VAGINA FOLLOWING RADIOTHERAPY FOR CERVICAL CANCER

1961 ◽  
Vol 16 (4) ◽  
pp. 550-552
Author(s):  
LEOPOLD G. KOSS ◽  
MYRON R. MELAMED ◽  
WILLIAM W. DANIEL
Keyword(s):  
Cervical Cancer ◽  
Epidermoid Carcinoma

Does Using Relapse Prevention Increase the Efficacy of a Program for Smoking Cessation?: An Empirical Study

1997 ◽  
Vol 81 (1) ◽  
pp. 291-296 ◽  
Author(s):  
Elisardo Becoña ◽  
Fernando L. Vázquez
Keyword(s):  
Smoking Cessation ◽  
Problem Solving ◽  
Relapse Prevention ◽  
Treatment Session ◽  
Self Control ◽  
Control Group ◽  
Self Monitoring ◽  
Behavioral Program ◽  
End Of Treatment ◽  
Multicomponent Program

The aim of this study was to assess the effectiveness of relapse prevention taught as a problem-solving procedure in increasing the efficacy of a behavioral program for smoking cessation at short- and longer-term, 12-mo. follow-up. 75 smokers were assigned randomly to two treatment groups, using an additional 40 smokers who attended an information session but did not receive any treatment session as a control group. The first group ( n = 40) received the standard behavioral multicomponent program of Becoña. The program included motivational contract, self-monitoring, information on smoking, nicotine fading, stimulus control, avoidance of withdrawal symptoms, physiological feedback, and progressive self-control. The second group ( n = 36), the relapse prevention group, were given the above program and an additional component of relapse prevention using a problem solving procedure. Both groups had 8 sessions of treatment. Analysis showed that at the end of treatment abstinence in the two groups was 80.0% and 61.1%, respectively, at the 12-mo. follow-ups 30.0% and 36.1%. These differences were not significant; however, both groups were significantly different from the control group at the end of treatment (0% abstinence) and at 12-mo. follow-ups (2.5% abstinence). These results show that the addition of this relapse prevention does not increase the number of smokers who quit or decrease the number who relapse. Further research should focus on the process of relapse and develop more effective procedures to help maintain abstinence.

scholarly journals Laser therapy in the treatment of dentine hypersensitivity

2004 ◽  
Vol 15 (2) ◽  
pp. 144-150 ◽  
Author(s):  
Thereza Christinna Cellos Gonçalves Pinheiro Ladalardo ◽  
Antonio Pinheiro ◽  
Roberto Augusto de Carvalho Campos ◽  
Aldo Brugnera Júnior ◽  
Fátima Zanin ◽  
...  
Keyword(s):  
Diode Laser ◽  
Age Groups ◽  
Treatment Session ◽  
Therapeutic Effects ◽  
Old Patients ◽  
Dentine Hypersensitivity ◽  
Nociceptive Stimulus ◽  
End Of Treatment ◽  
Minute Post ◽  
Numeric Scale

Cervical dentine hypersensitivity is the most frequent complaint among reported odontalgias. Thus, this study evaluated the effectiveness of two types of lasers (660 nm wavelength red, and 830 nm wavelength infrared) as dentine desensitizers, as well as both the immediate and late therapeutic effects in individuals 25 to 45 years of age. A total of 40 teeth with cervical exposure were treated in 4 sessions. They were divided into 2 groups according to treatment. A 660 nm wavelength red diode laser and an 830 nm wavelength infrared diode laser were used. Dentine sensitivity to cold nociceptive stimulus was evaluated by means of a pain numeric scale from zero to 10 before each treatment session, at 15 and 30 min after irradiation, and in a follow-up period of 15, 30 and 60 days after the end of treatment. Significant levels of dentinal desensitization were only found in patients ranging in age from 25 to 35 years. The 660 nm red diode laser was more effective than the 830 nm infrared laser and a higher level of desensitization was observed at the 15 and 30 minute post-irradiation examinations. The immediate and late therapeutic effects of the 660 nm red diode laser were more evident in 25-35-year-old patients compared with those of the 830 nm infrared diode laser, in terms of the different age groups.

Effect of chemoradiation for cervical cancer on transient decrease and variable expansion in T-cell infiltrate and diversity of T-cell repertoire.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 11557-11557
Author(s):  
Lauren Elizabeth Colbert ◽  
Stephanie Dorta-Estremera ◽  
Rebecca A. Previs ◽  
Patricia J. Eifel ◽  
Anuja Jhingran ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
T Cell ◽  
Complete Response ◽  
Cell Receptor ◽  
T Cell Subsets ◽  
Response To Treatment ◽  
Cell Repertoire ◽  
Cd8 Cells ◽  
Multiparametric Flow Cytometry ◽  
End Of Treatment

11557 Background: The effect of fractionated radiation on intratumoral immune infiltrate is unclear. The purpose of this study was to characterize local immune changes and treatment response during chemoradiation (CRT). Methods: Cervical cancer patients underwent cisplatin based CRT over 5 weeks with brachytherapy. Cervical DNA swabs and cytology brushings were collected at baseline, one week, three weeks and five weeks. Deep T cell receptor β sequencing (TCR; Adaptive, Seattle WA) and multiparametric flow cytometry (MPFC) were performed for each time point. T cell density (TCD) and productive clonality (PC) were analyzed. Cells separated from the tumor brushings were stained and fixed with antibodies to T cell subsets with activation and suppressor markers including CD3, CD4, CD8, Ki67, PD-1, CTLA-4, and ICOS. Changes in T cell subsets were evaluated as percentage of live lymphocytes. Results: Eight patients were evaluated using MPFC. CD4 and CD8 percentages were lowest at one week and subsequently expanded. The percentage of proliferating CD4 (CD4+ Ki67+) was highest at week 5 (1.19%). There was no change in percentage of CD8+ cells expressing PD1, CTLA4 or ICOS over the course of treatment. TCR diversity was assessed for 9 patients. At baseline, week 1, week 3 and week 5, median TCD for all patients were 0.046 (IQR 0.008 to 0.097), 0.021 (IQR 0.005 to 0.043), 0.035 (IQR 0.015 to 0.083), and 0.033 (IQR 0.017 to 0.110). Median productive clonality at each point was 0.05 (IQR 0.06 to 0.02), 0.03 (IQR 0.06 to 0.02), 0.04 (IQR 0.05 to 0.02) and 0.03 (IQR 0.01 to 0.05). PC fold count increased (1.69, SD 1.3) for complete response (CR) patients and decreased 0.3 (SD 0.008) for patients with recurrent (REC) disease (p = 0.1). One TCR sequence was common in 4/9 patients at the end of treatment and six sequences were common in 3/9 patients. Conclusions: Chemoradiation induces a transient decline in tumor infiltrating CD8+ and CD4+ cells, followed by a variable expansion in T-cells at the end of treatment with an increase in proliferation phenotypes. TCR sequencing revealed increase in productive clonality during radiation for patients with a complete response to treatment.

Subclinical thiamine deficiency: What is the most appropriate method of diagnosis and treatment?

2020 ◽  
Vol 18 (5) ◽  
pp. 614-616
Author(s):  
Hideki Onishi ◽  
Nozomu Uchida ◽  
Kumi Itami ◽  
Masakazu Sato ◽  
Saki Tamura ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Weight Loss ◽  
Thiamine Deficiency ◽  
Neuropsychiatric Symptoms ◽  
Adjustment Disorder ◽  
Diagnosis And Treatment ◽  
Normal Range ◽  
Psychiatric Examination ◽  
End Of Treatment

AbstractObjectivesThe symptoms of thiamine deficiency vary considerably and asymptomatic cases; i.e., subclinical thiamine deficiency (SCTD), are known to exist. However, there is no information available on the treatment of SCTD.MethodsWe report a patient who underwent intravenous thiamine replacement therapy for about a month after being diagnosed with SCTD, but who developed SCTD again about three weeks after finishing the treatment.ResultsThe patient was a 64-year-old woman who, after starting treatment for cervical cancer, complained of anxiety and underwent an initial psychiatric examination. The psychiatric diagnosis was an adjustment disorder. Based on the possibility of SCTD complications due to her decreased appetite and weight loss, her serum thiamine concentration was measured and found to be low. Therefore, thiamine was administered intravenously for 29 days. At the end of treatment, thiamine administration was discontinued as there were no apparent neuropsychiatric symptoms or problems with appetite. Twenty-three days later, there were still no problems with appetite or neuropsychiatric symptoms, but a follow-up blood sample revealed that her serum thiamine was again below the normal range.Significance of resultsCurrently, there is no information available regarding the diagnosis and treatment of SCTD in cancer patients. In some cases, such as this case, the deficiency recurs without any symptoms indicative of SCTD; therefore, further examination for diagnosis and treatment is necessary.

scholarly journals EVALUATION OF IN-VITRO CYTOTOXIC ACTIVITY OF CHLOROFORM EXTRACT OF SIDA ACUTA BURM.F.

2017 ◽  
Vol 10 (2) ◽  
pp. 143 ◽  
Author(s):  
Lakshmi Kanta Kanthal
Keyword(s):  
Cervical Cancer ◽  
Cytotoxic Activity ◽  
Cell Lines ◽  
Chloroform Extract ◽  
Epidermoid Carcinoma ◽  
Sida Acuta ◽  
Human Cervical Cancer Cell ◽  
Human Epidermoid Carcinoma ◽  
Human Cervical Cancer

ABSTRACTObjective: The aim of the present work was to investigate the in-vitro cytotoxic activity of chloroform extract of Sida acuta Burm.f.Methods: The in-vitro cytotoxic activity of chloroform extract was performed by MTT assay method against A-431 (Human epidermoid carcinoma) and HeLa (Human cervical cancer) cell lines.Results: The various concentration of crude chloroform extract (1000, 500, 250, 125, 62.5 µg/ml concentration) of Sida acuta whole plant was performed for cytotoxic activity. Effect of inhibition of cell growth showed significantly cytotoxic against A-431 cell lines (human epidermoid carcinoma) with an of 375±0.00 and HeLa cell lines (human cervix carcinoma with an IC50 (inhibit cell growth by 50%) 610.00±2.5. The results obtained from the study indicate significant cytotoxic activity. The result of anticancer activity study in cell lines of the extract indicates that Sida acuta has anticancer activity against A-431-Human epidermoid carcinoma, HeLa-Human cervical cancer cell lines.Conclusion: The present study concluded that the chloroform extract of Sida acuta Burm.f. posses potent cytotoxic activity.Keywords: Sida acuta Burm.f., Chloroform extract, Cytotoxic activity, IC50.      

scholarly journals Leiomyosarcoma of the inferior vena cava with renal metastasis: An unusual case and diagnostic challenge

2014 ◽  
Vol 8 (9-10) ◽  
pp. 358
Author(s):  
Garson Chan ◽  
Tadeusz Kroczak ◽  
Darrel Drachenberg
Keyword(s):  
Inferior Vena Cava ◽  
Poor Prognosis ◽  
Renal Mass ◽  
Unusual Case ◽  
Inferior Vena ◽  
Vena Cava ◽  
Malignant Tumours ◽  
Diagnostic Challenge ◽  
Open Partial Nephrectomy ◽  
Renal Metastasis

Leiomyosarcomas are exceedingly rare malignant tumours with a very poor prognosis. We present a 78-year-old patient with a small renal and paracaval mass. Surgery included right open partial nephrectomy and resection of the paracaval mass to treat the presumed renal cell carcinoma. Pathology revealed the tumour tobe leiomyosarcoma (LMS). This is only the second documented report of an inferior vena cava LMS presenting along with an ipsilateral renal mass.

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