scholarly journals PENGGUNAAN TABIR SURYA BAGI KESEHATAN KULIT

2019 ◽  
Vol 11 (1) ◽  
pp. 87
Author(s):  
Prima Minerva
Keyword(s):  
Skin Cancer ◽  
Adverse Effects ◽  
Uv Light ◽  
Light Exposure ◽  
Premature Aging ◽  
Negative Effects ◽  
Physical Protection ◽  
Skin Immunity ◽  
Long Time ◽  
The Right

Most activities are done outside the home often make the skin exposed to UV light. Exposure UV light excessively or in a long time can cause the occurrence of skin disorders such as Sunburn, premature aging, lowering skin immunity to skin cancer. In preventing the negative effects of UV light on the skin, various ways can be done such as by using a protector such as clothes, hats, glasses or umbrellas. But this physical protection is not sufficient because of the UV light penetrating power. Sunscreen is a skin care cosmetic that provides physical protection against UV light. Proper use of sunscreen and routine can protect the skin from the negative effects of UV light. This paper describes the effects of UV light on the skin, the function of sunscreen and the right use and compatible types sunscreen in maintaining skin health from the adverse effects of UV light.

scholarly journals Suspected Pulmonary Metastasis of Actinic Cutaneous Squamous Cell Carcinoma

2017 ◽  
Vol 2017 ◽  
pp. 1-4 ◽  
Author(s):  
Monet E. Meter ◽  
David J. Nye ◽  
Christian R. Galvez
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Actinic Keratosis ◽  
Uv Light ◽  
Light Exposure ◽  
Thoracoscopic Surgery ◽  
Wedge Resection ◽  
Lung Lesion ◽  
The Right

Introduction. It is rare for actinic or squamous cell carcinoma (SCC) in situ to metastasize. Case Presentation. A 67-year-old male had a significant medical history including severe psoriatic arthritis treated with UVB, methotrexate, and rapamycin. He had twenty-five different skin excisions of actinic keratosis four of which were invasive SCC. Our patient developed shortness of breath necessitating a visit to the emergency department. A CT scan of his chest revealed a mass in the right lower lung. A subsequent biopsy of the mass revealed well-differentiated SCC. He underwent thoracoscopic surgery with wedge resection of the lung lesion. Discussion. Actinic keratosis (AK) is considered precancerous and associated with UV exposure. It exists as a continuum of progression with low potential for malignancy. The majority of invasive SCCs are associated with malignant progression of AK, but only 5–10% of AKs will progress to malignant potential. Conclusion. In this case, a new finding of lung SCC in the setting of multiple invasive actinic cutaneous SCC associated with a history of extensive UV light exposure and immunosuppression supports a metastatic explanation for lung cancer.

scholarly journals Do We Utilize Our Knowledge of the Skin Protective Effects of Carotenoids Enough?

Antioxidants ◽  
2019 ◽  
Vol 8 (8) ◽  
pp. 259 ◽  
Author(s):  
Balić ◽  
Mokos
Keyword(s):  
Skin Cancer ◽  
Uv Light ◽  
Porphyria Cutanea Tarda ◽  
Primary Source ◽  
Protective Role ◽  
Premature Aging ◽  
Protective Effects ◽  
Public Attention ◽  
Potential Health ◽  
Stress Dependent

Due to their potential health-promoting effects, carotenoids have drawn both scientific and public attention in recent years. The primary source of carotenoids in the human skin is diet, mainly fruits, vegetables, and marine product, but they may originate from supplementation and topical application, too. In the skin, they accumulate mostly in the epidermis and act as a protective barrier to various environmental influences. Namely, the skin is exposed to numerous environmental factors, including ultraviolet radiation (UVR), air pollution, and smoking, that cause oxidative stress within the skin with consequent premature (extrinsic) aging. UVR, as the most prominent environmental factor, may cause additional detrimental skin effects, such as sunburn, DNA damage, and skin cancer. Therefore, photoprotection is the first line intervention in the prevention of premature aging and skin cancer. Numerous studies have demonstrated that carotenoids, particularly β-carotene, lycopene, lutein, and astaxanthin, have photoprotective effects, not only through direct light-absorbing properties, but also through their antioxidant effects (scavenging reactive oxygen species), as well as by regulation of UV light-induced gene expression, modulation of stress-dependent signaling, and/or suppression of cellular and tissue responses like inflammation. Interventional studies in humans with carotenoid-rich diet have shown its photoprotective effects on the skin (mostly by decreasing the sensitivity to UVR-induced erythema) and its beneficial effects in prevention and improvement of skin aging (improved skin elasticity and hydration, skin texture, wrinkles, and age spots). Furthermore, carotenoids may be helpful in the prevention and treatment of some photodermatoses, including erythropoietic protoporphyria (EPP), porphyria cutanea tarda (PCT) and polymorphous light eruption (PMLE). Although UVR is recognized as the main etiopathogenetic factor in the development of non-melanoma skin cancer (NMSC) and melanoma, and the photoprotective effects of carotenoids are certain, available studies still could not undoubtedly confirm the protective role of carotenoids in skin photocarcinogenesis.

scholarly journals A Rare Presentation of Actinic Keratosis Affecting the Tarsal Conjunctiva and Review of the Literature

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Selina Khan ◽  
Melanie Chak
Keyword(s):  
Actinic Keratosis ◽  
Uv Light ◽  
Light Exposure ◽  
Excisional Biopsy ◽  
Eyelid Margin ◽  
Rare Presentation ◽  
Upper Eyelid ◽  
The Right ◽  
Learning Points

We report an unusual case of actinic keratosis (AK) of the tarsal conjunctiva in a 63-year-old man. Examination revealed a crusty, leukoplakic lesion prone to bleeding on the tarsal conjunctiva of the right upper eyelid. This was treated by surgical excisional biopsy. At 1-year follow-up, there was no evidence of recurrence and the surgical site was completely healed without conjunctival scarring. Current opinion cites excessive exposure to ultraviolet (UV) radiation, in particular UV-B in sunlight, as the causative agent in developing AK. In the case we present, the tarsal conjunctiva is an unusual place for actinic keratosis due to the lack of direct UV-light exposure. The key learning points are to evert the upper eyelid during examination especially if the lesion involves the eyelid margin and, secondly, to ensure risk factors are addressed during the history.

Rancang Bangun Sistem Penerimaan Dan Mutasi Barang Pada PDAM Tirta Kerta Raharja

Sensi Journal ◽  
2020 ◽  
Vol 6 (2) ◽  
pp. 236-246
Author(s):  
Ilamsyah Ilamsyah ◽  
Yulianto Yulianto ◽  
Tri Vita Febriani
Keyword(s):  
System Analysis ◽  
Object Oriented ◽  
Analysis Method ◽  
Web Based ◽  
Visual Modeling ◽  
Long Time ◽  
The Right ◽  
And Control ◽  
Web Based System ◽  
The Web

The right and appropriate system of receiving and transferring goods is needed by the company. In the process of receiving and transferring goods from the central warehouse to the branch warehouse at PDAM Tirta Kerta Raharja, Tangerang Regency, which is currently done manually is still ineffective and inaccurate because the Head of Subdivision uses receipt documents, namely PPBP and mutation of goods, namely MPPW in the form of paper as a submission media. The Head of Subdivision enters the data of receipt and mutation of goods manually and requires a relatively long time because at the time of demand for the transfer of goods the Head of Subdivision must check the inventory of goods in the central warehouse first. Therefore, it is necessary to hold a design of information systems for the receipt and transfer of goods from the central warehouse to a web-based branch warehouse that is already database so that it is more effective, efficient and accurate. With the web-based system of receiving and transferring goods that are already datatabed, it can facilitate the Head of Subdivision in inputing data on the receipt and transfer of goods and control of stock inventory so that the Sub Head of Subdivision can do it periodically to make it more effective, efficient and accurate. The method of data collection is done by observing, interviewing and studying literature from various previous studies, while the system analysis method uses the Waterfall method which aims to solve a problem and uses design methods with visual modeling that is object oriented with UML while programming using PHP and MySQL as a database.

scholarly journals Stability and ocular biodistribution of topically administered PLGA nanoparticles

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sean Swetledge ◽  
Renee Carter ◽  
Rhett Stout ◽  
Carlos E. Astete ◽  
Jangwook P. Jung ◽  
...  
Keyword(s):  
Uv Light ◽  
Light Exposure ◽  
Polymeric Nanoparticles ◽  
Plga Nanoparticles ◽  
Eye Disease ◽  
Control Group ◽  
Eye Tissues ◽  
Nanoparticle Morphology ◽  
The Stability

AbstractPolymeric nanoparticles have been investigated as potential delivery systems for therapeutic compounds to address many ailments including eye disease. The stability and spatiotemporal distribution of polymeric nanoparticles in the eye are important regarding the practical applicability and efficacy of the delivery system in treating eye disease. We selected poly(lactic-co-glycolic acid) (PLGA) nanoparticles loaded with lutein, a carotenoid antioxidant associated with eye health, as our model ophthalmic nanodelivery system and evaluated its stability when suspended in various conditions involving temperature and light exposure. We also assessed the ocular biodistribution of the fluorescently labeled nanoparticle vehicle when administered topically. Lutein-loaded nanoparticles were stable in suspension when stored at 4 °C with only 26% lutein release and no significant lutein decay or changes in nanoparticle morphology. When stored at 25 °C and 37 °C, these NPs showed signs of bulk degradation, had significant lutein decay compared to 4 °C, and released over 40% lutein after 5 weeks in suspension. Lutein-loaded nanoparticles were also more resistant to photodegradation compared to free lutein when exposed to ultraviolet (UV) light, decaying approximately 5 times slower. When applied topically in vivo, Cy5-labled nanoparticles showed high uptake in exterior eye tissues including the cornea, episcleral tissue, and sclera. The choroid was the only inner eye tissue that was significantly higher than the control group. Decreased fluorescence in all exterior eye tissues and the choroid at 1 h compared to 30 min indicated rapid elimination of nanoparticles from the eye.

scholarly journals Subway Gearbox Fault Diagnosis Algorithm Based on Adaptive Spline Impact Suppression

Entropy ◽  
2021 ◽  
Vol 23 (6) ◽  
pp. 660
Author(s):  
Zhongshuo Hu ◽  
Jianwei Yang ◽  
Dechen Yao ◽  
Jinhai Wang ◽  
Yongliang Bai
Keyword(s):  
Fault Diagnosis ◽  
Spline Interpolation ◽  
Reference Value ◽  
High Amplitude ◽  
Engineering Practice ◽  
Negative Effects ◽  
Short Term ◽  
Time Domain Signal ◽  
Gearbox Vibration ◽  
Long Time

In the signal processing of real subway vehicles, impacts between wheelsets and rail joint gaps have significant negative effects on the spectrum. This introduces great difficulties for the fault diagnosis of gearboxes. To solve this problem, this paper proposes an adaptive time-domain signal segmentation method that envelopes the original signal using a cubic spline interpolation. The peak values of the rail joint gap impacts are extracted to realize the adaptive segmentation of gearbox fault signals when the vehicle was moving at a uniform speed. A long-time and unsteady signal affected by wheel–rail impacts is segmented into multiple short-term, steady-state signals, which can suppress the high amplitude of the shock response signal. Finally, on this basis, multiple short-term sample signals are analyzed by time- and frequency-domain analyses and compared with the nonfaulty results. The results showed that the method can efficiently suppress the high-amplitude components of subway gearbox vibration signals and effectively extract the characteristics of weak faults due to uniform wear of the gearbox in the time and frequency domains. This provides reference value for the gearbox fault diagnosis in engineering practice.

An Analysis of the Structure of Trade Between Australia and China: An Australian Perspective

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Andrew Marks
Keyword(s):  
Adverse Effects ◽  
Employment Growth ◽  
Strategic Trade Policy ◽  
Negative Effects ◽  
Trade Surplus ◽  
Strategic Trade ◽  
Primary Products ◽  
The World ◽  
Balance Of Trade ◽  
Structure Of Trade

AbstractThe structure of exports from Australia to China reveals the dominance of primary products with the structure of imports from this country reflecting the over-reliance on manufacturing goods. This has restrained and led to fluctuations in the balance of trade surplus in Australia thereby leading to lower than otherwise and more volatile output and employment growth. The pattern of trade between Australia and China is representative of trade between Australia and the rest of the world thereby magnifying these adverse effects. Strategic trade policy has the potential to alleviate these negative effects on output and employment growth in Australia.

scholarly journals Achalasia Cardia: A Mimicker of Pulmonary Tuberculosis in a High-Burden Setting

2020 ◽  
Author(s):  
Pratibha Sharma ◽  
Ranganath T. Ganga
Keyword(s):  
South Africa ◽  
Adverse Effects ◽  
Respiratory Symptoms ◽  
Antitubercular Drugs ◽  
Achalasia Cardia ◽  
High Burden ◽  
Antitubercular Treatment ◽  
Common Diagnosis ◽  
National Tuberculosis ◽  
Long Time

AbstractBRICS (Brazil, Russia, India, China, and South Africa) countries account for more than two-thirds of the global tuberculosis burden. Tuberculosis is a common diagnosis in patients presenting with chronic respiratory symptoms in these high-burden countries, which results in other diseases being missed easily. The national tuberculosis elimination program encourages to start antitubercular treatment on a clinical basis even without any confirmatory evidence. This has resulted in missing many nontuberculosis cases and unnecessarily exposing to adverse effects of antitubercular drugs. Here we report one such instance where achalasia cardia was missed for a long time.

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