scholarly journals Injuries in the time of COVID-19

2020 ◽  
Vol 40 (11/12) ◽  
pp. 336-341 ◽  
Author(s):  
Glenn Keays ◽  
Debbie Freeman ◽  
Isabelle Gagnon
Keyword(s):  
Motor Vehicle ◽  
Pediatric Population ◽  
Pediatric Trauma ◽  
Age Groups ◽  
Trauma Centre ◽  
Ed Visits ◽  
Injury Reporting ◽  
Using Data ◽  
The Impact

Introduction Research has shown that during the 2003 SARS pandemic, emergency department (ED) visits among the pediatric population decreased. We set out to investigate if this was also true for injury-related ED visits during the COVID-19 pandemic. Methods Using data from the Canadian Hospitals Injury Reporting and Prevention Program (CHIRPP), we looked at 28 years of injury-related ED visits at the Montreal Children’s Hospital, a provincially designated Pediatric Trauma Centre. We compared data from a two-month period during the COVID-19 lockdown (16 March to 15 May) to the same period in previous years (1993–2019) to determine whether the 2020 decrease in ED visit numbers was unprecedented (i.e. a similar decrease had never occurred) for different age groups, nature of injuries, mechanisms and severity. Results The 2020 decrease was unprecedented across all age groups between 1993 and 2019. When compared with the 2015 to 2019 average, the decrease was smallest in children aged 2 to 5 years (a 35% decrease), and greatest in the group aged 12 to 17 years (83%). Motor vehicle collisions and sports-related injuries practically vanished during the COVID-19 lockdown. Surprisingly, more children aged 6 to 17 years presented with less urgent injuries during the COVID-19 lockdown than in previous years. Conclusion As was the case with SARS in 2003, COVID-19 acted as a deterrent for pediatric ED visits. The lockdown in particular had a profound impact on injury-related visits. The de-confinement period will be monitored to determine the impact in both the short and the long term.

scholarly journals P040: Epidemiology of gun related injuries among Canadian children and youth from 2005-2013: a CHIRPP study

CJEM ◽  
2017 ◽  
Vol 19 (S1) ◽  
pp. S91
Author(s):  
C.M. Cox ◽  
S. Stewart ◽  
K.F. Hurley
Keyword(s):  
Pediatric Population ◽  
Gun Control ◽  
Simple Linear Regression ◽  
Eye Injuries ◽  
Unintentional Injuries ◽  
Exact Test ◽  
Male Predominance ◽  
Self Harm ◽  
Ed Visits ◽  
Injury Reporting

Introduction: Gun related injuries were last reported by the Canadian Hospitals Injury Reporting and Prevention Program (CHIRPP) in 2005. Since that time, Canadian gun control is less stringent and non-powder guns are increasingly popular. We aim to describe trends in pediatric gun related injuries and deaths since 2005. Methods: This is a retrospective review of CHIRPP data. The dataset included pediatric (age 0-19 years) gun-related injuries and deaths reported by participating CHIRPP emergency departments (ED) from 2005-2013. Variables were tested using Fisher’s exact test and simple linear regression. Results: There were 421 records of gun-related injuries in the database. Three hundred and twenty-nine occurred from use of non-powder guns, 85 occurred from use of powder-guns, and in 7 cases the type of gun was not clear. The number of gun-related injuries per 100 000 ED visits remained stable from 2005-2013 with a male predominance (n=366, 87%). Most injuries resulted from non-powder guns and were unintentional. Injuries most often occurred in the context of recreation (n=181) and sport (n=51). One hundred fifty four eye injuries were reported, 98% of which were from a non-powder gun. Forty-six individuals required admission to hospital and 2 died in the ED. Nine of 10 intentional self-harm injuries were inflicted with a powder gun. Conclusion: This study describes the injuries and circumstances in which pediatric gun-related injury and death occur in Canada. Unintentional injuries caused by non-powder guns were most common. Though less fatal than powder guns, non-powder guns can still cause life-altering eye injuries. This evidence can inform injury prevention programs to target specific circumstances in which the pediatric population is most vulnerable.

scholarly journals Data-Driven Approach for Predicting and Explaining the Risk of Long-Term Unemployment

2020 ◽  
Vol 214 ◽  
pp. 01023
Author(s):  
Linan (Frank) Zhao
Keyword(s):  
Machine Learning ◽  
Age Groups ◽  
Learning Models ◽  
Public Authorities ◽  
Ensemble Machine Learning ◽  
European Public ◽  
Data Driven Approach ◽  
Using Data ◽  
Machine Learning Models

Long-term unemployment has significant societal impact and is of particular concerns for policymakers with regard to economic growth and public finances. This paper constructs advanced ensemble machine learning models to predict citizens’ risks of becoming long-term unemployed using data collected from European public authorities for employment service. The proposed model achieves 81.2% accuracy on identifying citizens with high risks of long-term unemployment. This paper also examines how to dissect black-box machine learning models by offering explanations at both a local and global level using SHAP, a state-of-the-art model-agnostic approach to explain factors that contribute to long-term unemployment. Lastly, this paper addresses an under-explored question when applying machine learning in the public domain, that is, the inherent bias in model predictions. The results show that popular models such as gradient boosted trees may produce unfair predictions against senior age groups and immigrants. Overall, this paper sheds light on the recent increasing shift for governments to adopt machine learning models to profile and prioritize employment resources to reduce the detrimental effects of long-term unemployment and improve public welfare.

scholarly journals Progress in Pediatric Kidney Transplantation

2014 ◽  
Vol 7 (1) ◽  
pp. 115-122
Author(s):  
Jodi M. Smith ◽  
Vikas R. Dharnidharka
Keyword(s):  
Kidney Transplantation ◽  
Graft Survival ◽  
Pediatric Population ◽  
Short Term ◽  
Allocation Policy ◽  
Pediatric Kidney Transplantation ◽  
Timely Access ◽  
The Impact ◽  
Made In

Significant progress has been made in pediatric kidney transplantation. Advances in immunosuppression have dramatically decreased rates of acute rejection leading to improved short term graft survival but similar improvements in long term graft survival remain elusive. Changes in allocation policy provide the pediatric population with timely access to transplant but there remains concern about the impact of less HLA matching and a decrease in living donors. This report presents data from North America on these successes and the ongoing challenges that face the pediatric transplant community.

Traumatic brain injury in pediatric patients: evidence for the effectiveness of decompressive surgery

2011 ◽  
Vol 31 (5) ◽  
pp. E5 ◽  
Author(s):  
Geoffrey Appelboom ◽  
Stephen D. Zoller ◽  
Matthew A. Piazza ◽  
Caroline Szpalski ◽  
Samuel S. Bruce ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Pediatric Patients ◽  
Pediatric Population ◽  
Adult Population ◽  
Pediatric Trauma ◽  
Anatomical Variations ◽  
Decompressive Surgery ◽  
Pediatric Populations ◽  
The Impact

Traumatic brain injury (TBI) is the current leading cause of death in children over 1 year of age. Adequate management and care of pediatric patients is critical to ensure the best functional outcome in this population. In their controversial trial, Cooper et al. concluded that decompressive craniectomy following TBI did not improve clinical outcome of the analyzed adult population. While the study did not target pediatric populations, the results do raise important and timely clinical questions regarding the effectiveness of decompressive surgery in pediatric patients. There is still a paucity of evidence regarding the effectiveness of this therapy in a pediatric population, and there is an especially noticeable knowledge gap surrounding age-stratified interventions in pediatric trauma. The purposes of this review are to first explore the anatomical variations between pediatric and adult populations in the setting of TBI. Second, the authors assess how these differences between adult and pediatric populations could translate into differences in the impact of decompressive surgery following TBI.

scholarly journals Soccer-related head injuries—analysis of sentinel surveillance data collected by the electronic Canadian Hospitals Injury Reporting and Prevention Program

2019 ◽  
Vol 25 (6) ◽  
pp. 378-384
Author(s):  
Sarah Zutrauen ◽  
Steven McFaull ◽  
Minh T Do
Keyword(s):  
Prevention Program ◽  
Brain Injuries ◽  
Head Injuries ◽  
Surveillance Data ◽  
Soccer Players ◽  
Closed Head Injuries ◽  
Risk Of Injury ◽  
Ed Visits ◽  
Injury Reporting ◽  
Using Data

Abstract Background Participating in sports is a great way to gain physical, psychological, and social benefits. However, it also carries the risk of injury. Soccer is one of the most popular sports worldwide, and in recent years, there have been concerns about potential vulnerabilities to head injuries. Objectives To investigate soccer-related head injuries (SRHIs), using data from the electronic Canadian Hospitals Injury Reporting and Prevention Program (eCHIRPP) surveillance system. Specifically, we aim to compare characteristics of SRHI cases to all head injury cases within the eCHIRPP database. Methods Descriptive analyses of emergency department (ED) injury surveillance data (2011 to 2017) for individuals aged 5 to 29 years from all participating eCHIRPP sites. Computation of proportionate injury ratios (PIR) comparing SRHIs to all head injuries reported to eCHIRPP, and 95% confidence intervals (CI). Results A total of 3,970 SRHIs were reported to eCHIRPP. Injuries were from contact with another player, the ball, ground, goal-post, and other causes. Of the injuries caused by contact with the ball, 9% were from purposely directing the ball with the head (heading). A higher proportion of concussions (PIR=1.32, 95% confidence interval [CI]: 1.27 to 1.37) and minor closed head injuries (PIR=1.20, 95% CI: 1.15 to 1.26) were observed in soccer players. Higher proportions of head injuries occurred in organized soccer and soccer played outdoors. However, admission to the ED for a SRHI was rare (PIR=0.40, 95% CI: 0.30 to 0.55). Conclusions Overall, elevated proportions of brain injuries were observed among soccer players, however, these injuries were unlikely to result in a hospital admission. Moreover, purposely heading the ball contributed to few ED visits.

Whole lung irradiation for completely responding pulmonary metastases in pediatric Ewing sarcoma

2020 ◽  
Vol 16 (15) ◽  
pp. 1043-1051
Author(s):  
Hagar Elghazawy ◽  
Azza Nasr ◽  
Iman Zaky ◽  
Manal Zamzam ◽  
Ahmed Elgammal ◽  
...  
Keyword(s):  
Pulmonary Metastases ◽  
Pediatric Population ◽  
Event Free Survival ◽  
Relapse Free Survival ◽  
Free Survival ◽  
Real Value ◽  
Lung Irradiation ◽  
Whole Lung Irradiation ◽  
The Impact

Aim: Scarce data assessing the real value of whole lung irradiation (WLI) in Ewing’s sarcoma (ES) with lung-only metastasis, with published conflicting results. We studied the impact of WLI in a homogenous pediatric population. Materials & methods: Retrospective study evaluating the survival outcomes of WLI in these patients. Results: Out of 163 metastatic ES; 41 patients were eligible for WLI. 30 patients (73.1%) received WLI (+ve) while 11 patients (26.8%) did not receive WLI (-ve). Five-year event-free survival was statistically significant in WLI (+ve). Five-year pulmonary relapse-free survival showed trend for improvement with WLI (+ve), while 5-year overall survival was not statistically significant between the two arms. Conclusion: WLI added significantly to the long term clinical outcome of metastatic ES patients, with no irreversible toxicity.

scholarly journals 1558. A Population Pharmacokinetic Model for Posaconazole Intravenous Solution and Oral Powder for Suspension Formulations in Pediatric Patients With Neutropenia

2019 ◽  
Vol 6 (Supplement_2) ◽  
pp. S569-S569
Author(s):  
Gregory A Winchell ◽  
Rik de Greef ◽  
Rebecca E Wrishko ◽  
Eric Mangin ◽  
Hetty Waskin ◽  
...  
Keyword(s):  
Goodness Of Fit ◽  
Geometric Mean ◽  
Age Groups ◽  
Invasive Fungal Disease ◽  
Population Pharmacokinetic ◽  
Once Daily ◽  
Intravenous Solution ◽  
Backward Procedure ◽  
Using Data ◽  
The Impact

Abstract Background Posaconazole is approved in adults for prophylaxis and treatment of invasive fungal disease. Two formulations that offer weight-based dosing—intravenous (IV) and oral powder for suspension (PFS)—are being evaluated in children. A population pharmacokinetic (popPK) approach was used to characterize and predict the PK exposure of posaconazole PFS and IV formulations in children to identify dosages associated with achieving a target PK of 1200 ng/mL as the mean Cavg and individual Cavg ≥500 ng/mL and <2500 ng/mL in ~90% of patients. Methods A popPK model was developed through nonlinear mixed-effects modeling using data obtained from a trial in children with neutropenia (ClinicalTrials.gov, NCT02452034; Merck protocol, MK-5592-097). Three dose cohorts (3.5, 4.5, and 6 mg/kg/day [≤300 mg/day]) were studied in two age groups (2–<7 years and 7–17 years). Posaconazole IV was administered twice on day 1 then once daily through at least day 10, followed by PFS once daily through day 28 at clinician discretion. A compartmental model, including both formulations, was fit to the data. Model selection was based on the Log-Likelihood Criterion, goodness-of-fit plots, and scientific plausibility. Significance of the covariates was assessed in a stepwise forward inclusion/backward procedure. An additional assessment characterized the impact of different food covariates on bioavailability. Results An open one-compartmental PK model with first-order absorption and estimated bioavailability, as well as allometrically scaled effects of body weight on clearance and volume, adequately described the PK of posaconazole IV and PFS formulations. Model predictions are shown in the Table. Effects of the different food covariates were not statistically significant. Simulations indicated that for the 6-mg/kg/d dose, model-predicted Cavg generally met PK targets. Model-predicted Cavg was ≥500 ng/mL in >90% of subjects in all cohorts. The 1200-ng/mL target geometric mean Cavg was achieved for all but the 2–<7 years cohort receiving the PFS formulation. Conclusion This popPK-based analysis demonstrated that the 6-mg/kg/d dose of IV or PFS posaconazole formulation (≤300 mg/days) is appropriate for children (2–17 years) and that PFS can be administered without regard to food. Disclosures All authors: No reported disclosures.

scholarly journals Epidemiology of Pediatric Trauma and Its Patterns in Western Iran: A Hospital Based Experience

2015 ◽  
Vol 8 (6) ◽  
pp. 139 ◽  
Author(s):  
Fereshteh Jalalvandi ◽  
Peyman Arasteh ◽  
Roya Safari Faramani ◽  
Masoumeh Esmaeilivand
Keyword(s):  
Head And Neck ◽  
Traffic Accidents ◽  
Road Traffic ◽  
Pediatric Population ◽  
Care Center ◽  
Pediatric Trauma ◽  
Age Groups ◽  
Road Traffic Accidents ◽  
Orthopedic Injury ◽  
The Hours

<p><strong>BACKGROUND &amp; OBJECTIVE:</strong><em> </em>Trauma is a major cause of mortality in children aged 1 to 14 years old and its patterns differs from country to country. In this study we investigated the epidemiology and distribution of non-intentional trauma in the pediatric population.</p><p><strong>MATERIALS &amp; METHODS: </strong>The archives of 304 children below 10 years old who presented to Taleghani trauma care center in Kermanshah, Iran from March to September 2008, were reviewed. Patients’ demographic and injury related information were registered. The participants were categorized into three age groups of 0-2, 3-6 and 7-10 years old and the data was compared among age groups and between both sexes.</p><p><strong>FINDINGS: </strong>The most common cause for trauma was falling from heights (65.5%) and road traffic accidents (16.4%). The most common anatomical sites of injury were the upper limbs followed by the head and neck (36.8% and 31.2%, respectively). Injuries mostly occurred in homes (67.4%). The injuries were mostly related to the orthopedics and the neurosurgery division (84.1% and 13.1%, respectively). Accident rates peaked during the hours of 18-24 (41.3%). Male and female patients did display any difference regarding the variables.</p><p>Children between the ages of 0-2 years old had the highest rate of injury to the head and neck area (40.3%) (p=0.024). Falls and road traffic accidents displayed increasing rates from the ages of 0-2 to 3-6 and decreasing rates to the ages of 7-10 years old (p=0.013). From the ages of 0-2 to 3-6 years old, street accidents increased and household traumas decreased. After that age household trauma rates increased and street accidents decreased (p=0.005). Children between the ages of 7-10 years old had the highest rate of orthopedic injury (p=0.029).</p><p><strong>CONCLUSION:</strong><em> </em>Special planning and health policies are needed to prevent road accidents especially in children between the ages of 3-6 years old. Since homes were the place where children between the ages of 0-2 were mostly injured, parents should be educated about the correct safety measures that they need to take regarding their children's environments. The orthopedics department needs to receive the most training and resources for the management of pediatric trauma.</p>

scholarly journals A Systematic Review of Recommendations of Long-Term Strategies for Researchers Using Data Science Techniques

Computers ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 35
Author(s):  
Gilberto Ayala-Bastidas ◽  
Hector G. Ceballos ◽  
Francisco J. Cantu-Ortiz
Keyword(s):  
Systematic Review ◽  
Data Science ◽  
Process Mining ◽  
Research Strategies ◽  
Scientific Content ◽  
Open Research ◽  
Using Data ◽  
Long Term Impact ◽  
The Impact

The impact of the strategies that researchers follow to publish or produce scientific content can have a long-term impact. Identifying which strategies are most influential in the future has been attracting increasing attention in the literature. In this study, we present a systematic review of recommendations of long-term strategies in research analytics and their implementation methodologies. The objective is to present an overview from 2002 to 2018 on the development of this topic, including trends, and addressed contexts. The central objective is to identify data-oriented approaches to learn long-term research strategies, especially in process mining. We followed a protocol for systematic reviews for the engineering area in a structured and respectful manner. The results show the need for studies that generate more specific recommendations based on data mining. This outcome leaves open research opportunities from two particular perspectives—applying methodologies involving process mining for the context of research analytics and the feasibility study on long-term strategies using data science techniques.

Terrorism and tourism in Israel

2016 ◽  
Vol 23 (6) ◽  
pp. 1343-1352 ◽  
Author(s):  
Marion Karl ◽  
Gordon Winder ◽  
Alexander Bauer
Keyword(s):  
Time Lag ◽  
Research Model ◽  
Long Term Effects ◽  
Short Term ◽  
Event Tourism ◽  
Using Data ◽  
Terrorist Event ◽  
The Impact ◽  
The Relationship

While the relation between terrorism and tourism has been an important topic for tourism research, the questions whether terrorism affects tourism immediately and how long after a terrorism event tourism recovers are, as yet, not clearly answered. The aim of this article is to better understand the magnitude and temporal scale of the impact of terrorism on tourism. To this end, a research model differentiating between short-term and long-term effects of terrorism on tourism is developed and analyzed for the destination Israel using data on tourists from Germany. The results show both short-term and long-term impacts with a time lag between the terrorist event and the beginning of tourism decline of 1 or up to 6 months. An economic influence on the development of tourist arrivals was not detected, but seasonality plays an important role in the relationship between terrorism and tourism.

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