scholarly journals Correlation of clinical profile toward oral manifestations of HIV/AIDS patients

2021 ◽  
Vol 33 (1) ◽  
pp. 56
Author(s):  
Maharani Laillyza Apriasari ◽  
Nur Aprilyani ◽  
Amy Nindia Carabelly ◽  
Juliyatin Putri Utami
Keyword(s):  
Periodontal Disease ◽  
Clinical Profile ◽  
Oral Manifestations ◽  
Human Immune System ◽  
Aids Patients ◽  
Cross Sectional ◽  
Cd4 Cell Count ◽  
Oral Manifestation ◽  
Oral Thrush ◽  
Hiv Aids

Introduction: Human Immunodeficiency Virus (HIV) exhibits the capability to weaken human immune system. The infected subject will later be more susceptible to suffer from opportunistic diseases when the CD4 cell count is lesser than 200 cell/µL. Oral Thrush, periodontal disease and xerostomia are common oral manifestations in AIDS patient which initially indicate the presence of HIV infection. No research has been conducted to discuss the association between oral manifestation HIV/AIDS toward socio-demographic and clinical profile of the HIV/AIDS patients. Therefore, this study was aimed to analyse the association between oral manifestation HIV/AIDS toward socio-demographic and clinical profile of the HIV/AIDS patients. Methods: This was an analysis study with cross sectional design performed in 2019. The data of clinical profil of HIV AIDS patient and oral manifestation were obtained from secondary data of medical record.The 55 samples were taken with total sampling technique.  Results: Chi-square test showed there was a significant correlation between number of  CD4 with candidiasis, oral thrush and periodontal disease. There was a significant correlation between duration of ARV therapy and candidiasis, oral thrush (p<0.05). Conclusion: There is a correlation between the number of CD4 cells and the duration of ARV treatment on candidiasis,oral thrush, periodontal disease and xerostomia.

scholarly journals Prevalence and factors related with the presence of oral manifestations in HIV/AIDS patients who attended health institutions in Cali, Colombia.

1969 ◽  
Vol 39 (4) ◽  
pp. 346-355
Author(s):  
Elisa María Pinzón ◽  
Sonia Marlene Bravo ◽  
Fabián Méndez ◽  
Gail Mildred Clavijo ◽  
Miguel Evelio León
Keyword(s):  
Self Report ◽  
Oral Manifestations ◽  
Aids Patients ◽  
Cross Sectional ◽  
Oral Manifestation ◽  
Oral Ulcers ◽  
Removable Dental Prosthesis ◽  
Health Institutions ◽  
Aids Diagnosis ◽  
Hiv Aids

Aim: To determine the prevalence and factors related with the presence of oral manifestations in HIV/AIDS patients who attended health institutions in Cali-Colombia. Materials and methods: A cross-sectional descriptive study was made in 319 patients who attended four health institutions in the city of Cali. The inclusion criteria were: being HIV positive patients, being over 18 years old, attending medical checkups and accepting participation. Pregnant women and inmates were excluded. Results: The general prevalence of oral manifestations was 77.1% (CI 95%: 72.4-81.7). The most frequent oral manifestation was xerostomia with 41.1% (CI 95%: 35.5-46.6), followed by the manifestations from mycotic origin [(35.7% (CI 95% 30.4-41)] bacterial [34.2% (CI 95%: 28.9-39.4)] virals [16.6 (CI 95% 12.5-20.7)], oral ulcers [7.5 (CI 95%: 4.6-10.4)] and neoplastics [3.8 (CI95% 1.6-5.8)]. The population studied did not show non-Hodgkin’s lymphoma. In the multivariate analysis, the presence of oral injuries was associated with time of HIV/AIDS diagnosis during the previous 12 months, detectable viral load, and presence of removable dental prosthesis and self-report of dry mouth. Conclusions: The prevalence of oral manifestations registered in this population is high compared with those reported world-wide. Considering the association found, our results suggest that oral injuries are initial clinic characteristics of the disease and may be useful to predict treatment failure and progression from HIV infection to AIDS.

scholarly journals Profile of HIV/AIDS Patients Coinfected with Tuberculosis in Bumi Wonorejo Health Centre and Santo Rafael Clinic Nabire, Papua

2021 ◽  
Vol 31 (4) ◽  
pp. 10
Author(s):  
Tri Nury Kridaningsih ◽  
Mirna Widiyanti ◽  
Setyo Adiningsih ◽  
Hotma Martogi Lorensi Hutapea ◽  
Eva Fitriana ◽  
...  
Keyword(s):  
Clinical Symptoms ◽  
Health Centre ◽  
Descriptive Study ◽  
Cd4 Count ◽  
Aids Patients ◽  
Cross Sectional ◽  
Oral Thrush ◽  
Cross Sectional Design ◽  
Almost All ◽  
Hiv Aids

<p class="Englishversionofabstract">HIV-TB co-infection still becomes a health problem in Indonesia, including in Nabire district, Papua province, which has the highest number of cases. HIV and TB infections are closely related and affect the epidemiology of one another. This study aims to determine the profile description of HIV-TB co-infected patients in Nabire. This research is a descriptive study with a cross-sectional design on 90 people with HIV/AIDS selected consecutively. Data were analyzed univariately and presented in the form of a frequency distribution table. The results showed that of 55 HIV/AIDS co-infected TB patients, almost all (90.9%) were Papuan ethnic, 70.9% were female and aged 30 to 49 years (50.9%) with a mean of 31.309.36 years. The majority of HIV-TB co-infected patients were married (63.6%), holding secondary education (58.2%), working (67.3%), engaging in sexual activity after 17 years of age, only having one sexual partner, and did not use drugs or obtain blood transfusions. The clinical profile of HIV-TB patients showed that 67.3% of the patients were with baseline CD4 count ≤350 cells/mm3, 64.8% had CD4 count at the time of study &gt;350 cells/mm3, and viral load values fewer than 5000 copies/ml (87.3%). The therapy most widely received for patients with HIV-TB coinfection was the combination of ARV 3TC+EFV+TDF (76.4%). The most common clinical symptoms of HIV/AIDS patients were weight loss (56.4%), cough (40%), recurrent oral thrush (36.4%), chickenpox (32.7%), and tuberculosis lymph nodes (18.2%).</p>

scholarly journals Oral manifestations of anemia in HIV/AIDS patients without ARV treatment

2017 ◽  
Vol 29 (1) ◽  
Author(s):  
Wahyu Hidayat ◽  
Tenny Setiani Dewi ◽  
Rudi Wisaksana
Keyword(s):  
Hiv Infection ◽  
Oral Manifestations ◽  
Blood Disorders ◽  
Aids Patients ◽  
Anemia Of Chronic Disease ◽  
Oral Manifestation ◽  
Aphthous Ulcers ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Hiv Aids

AbstractIntroduction: Acquired immunodeficiency syndrome (AIDS) is  a set of symptoms caused by decreases of the immune system that was infected by human immunodeficiency virus (HIV). Blood disorders often found in patient with HIV and associated with HIV infection. Mostly found disorders is anemia of chronic disease. The prevalence of anemia in HIV/AIDS patients reaches 70%. Oral manifestations of anemia are atrophy of the papillae on tongue, glossodynia, pallor, angular cheilitis, glossitis, aphthous ulcers/erosive lesions, candidiasis, and geographic tongue. There are many publications that uses anemia as indicator to determine the prognosis of HIV infection, thus the description of oral manifestation of anemia in the non-ARV HIV/AIDS patients is a necessity. The purpose of this study was to describe the oral manifestation of anemia in the non-ARV HIV/AIDS patients. Methods: The methods used were purposive random sampling. Samples were new HIV/AIDS patients who have not got antiretroviral (ARV) treatment. The study included 40 patients in Teratai Clinic Hasan Sadikin Hospital Bandung. Results: Oral manifestations of anemia were found amongst non-ARV HIV/AIDS patients, which were candidiasis in  37 patients, glossodynia in 28 patients, glossitis in 10 patients, and angular cheilitis in 1 patient. Conclusion: From the study found that oral manifestations of anemia that found in non-ARV HIV/AIDS patients were candidiasis, glossodynia, glossitis and angular cheilitis. HIV/AIDS patients with anemia needed to treat more intensive for better prognosis and quality of life.Keywords: Anemia, HIV/AIDS, Candidiasis, Glossitis, Glossodynia

scholarly journals Pulmonary tuberculosis and immunological profile of HIV/AIDS patients in Far West Nepal

2014 ◽  
Vol 3 (1) ◽  
pp. 8-13
Author(s):  
Madan Singh Bohara
Keyword(s):  
Pulmonary Tuberculosis ◽  
Clinical Manifestations ◽  
Public Health Problem ◽  
Hiv Positive ◽  
Major Public Health Problem ◽  
Aids Patients ◽  
Cross Sectional ◽  
Cd4 Cell Count ◽  
Study Participants ◽  
Hiv Aids

Background: Tuberculosis is itself a major public health problem in Nepal and the emergence HIV further complicated the issue. Tuberculosis is the most common cause of death among HIV/AIDS patients worldwide. Tuberculosis and HIV co-infection is associated with special diagnostic and ther apeutic challenges and constitutes an immense burden on healthcare system of heavily infected countries like Nepal. Objective: The objective of the study was to determine the prevalence of pulmonary tuberculosis and their immunologic profi les among HIV positive patients. Methods: A hospital based cross-sectional study was conducted from Januray 2012 to July 2012 among adult HIV-positive patients attending ART centers at Seti Zonal Hospital and Mahakali Zonal Hospital. Clinical and laboratory investigations including Acid Fast staining and culture were used to identify tuberculosis cases. Blood samples were collected to determine CD4+ lymphocyte count. A structured questionnaire was used to collect socio-demographic characteristics of study participants. The data was entered and analysed using SPSS version 16 software. Results: A total of 103 HIV positive participants were enrolled. Five (4.9%) of the study participants (three females and two males) were found to have pulmonary tuberculosis. Majority [4(80%)] of TB-HIV co-infection was found in 21-40 years age group. Similarly four (80%) of them were illiterate. Among five TB cases only two cases were detected by direct microscopy. In general it was observed that various clinical manifestations such as cough, chest pain, weight loss, loss of appetite etc. are more common in TB co-infected HIV patients in comparison to non-co-infected counterparts. Similarly, higher percentage of TB cases were seen in patients with low CD4+ count (<500/mm3). Conclusions: We found high prevalence of tuberculosis-HIV co-infection. More such cases were seen among those with low CD4+ cell count. Early detection of co-infection is very necessary to facilitate early ART initiation, thereby strengthening their immune status.DOI: http://dx.doi.org/10.3126/jkmc.v3i1.10917Journal of Kathmandu Medical CollegeVol. 3, No. 1, Issue 7, Jan.-Mar., 2014, page: 8-13

scholarly journals PENGARUH PENDEKATAN MELALUI KONSELING INTERPERSONAL TERHADAP RESPON SOSIAL, EMOSIONAL DAN SPIRITUAL PADA PASIEN HIV/AIDS

2020 ◽  
Vol 8 (1) ◽  
pp. 62
Author(s):  
Indah Jayani ◽  
Fatma Sayekti Ruffaida
Keyword(s):  
Opportunistic Infections ◽  
Sampling Technique ◽  
Wilcoxon Test ◽  
P Value ◽  
Social Emotional ◽  
Aids Patients ◽  
Cross Sectional ◽  
Before And After ◽  
The Right ◽  
Hiv Aids

Approach to PLWHA by providing interpersonal counseling is the right thing to do to overcome psychological problems including social, emotional and spiritual aspects of PLWHA. This study aims to look at the effect of interpersonal counseling on social, emotional and spiritual responses in HIV/ AIDS patients. This research is a type of non-experimental research with a cross-sectional approach. The sample is post-test people and tested positive for HIV in the Kediri region, which is 32 with purpossive sampling technique. Data on social, emotional and spiritual responses were obtained based on the results of data recapitulation from the instrument in the form of a questionnaire. The results of the study with the non-parametric Wilcoxon test showed there were differences between social responses of HIV/AIDS patients before and after given interpersonal counseling with p value = 0,000, there were differences between the emotional responses of HIV/AIDS patients before being given interpersonal counseling and after being given counseling with p value = 0,000, and there is a difference between spiritual responses in HIV/AIDS patients before being given interpersonal counseling and after being given interpersonal counseling with p value = 0,000. It can be concluded that interpersonal counseling influences social, emotional and spiritual responses of HIV/AIDS patients. It is recommended that the mentoring of HIV/AIDS patients through interpersonal counseling can continue so as to enhance physiological responses that will have an impact on disease prognosis, prevention of opportunistic infections and reduce mortality rates for HIV patients/ AIDS.

scholarly journals Opportunistic Infections and Associated Factors among HIV/AIDS Patients taking Ante-Retroviral Therapy at Selected Hospitals in Sidama Zone, Southern Ethiopia: A facility-based cross-sectional study

2019 ◽  
Author(s):  
Demelash Wachamo ◽  
Fisseha Bonja
Keyword(s):  
Associated Factors ◽  
Opportunistic Infections ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
High Morbidity ◽  
Major Public Health Problem ◽  
Sectional Study ◽  
Aids Patients ◽  
Cross Sectional ◽  
Hiv Aids

Abstract Background Opportunistic infections are late complications of HIV infection is the depletion of the immune system. It is a major public health problem and high morbidity AIDS patients die of AIDS-related infections in developing countries like Ethiopia. Identification of opportunistic infections (OIs) is important to develop a specific intervention. Therefore, this study aimed to assess the burden and associated factors of opportunistic infections.Method A facility-based cross-sectional study was conducted on 420 randomly selected HIV/AIDS patients taking anti-retroviral therapy. Data was collected from selected hospitals in Sidama Zone based on population proportion to size. Data was collected by a pre-tested questionnaire and a pre-tested checklist from the medical records of patients. Data entry and analyzed for descriptive and logistic regression models by SPSS v.23. The result declared as statistically significant at p < 0.05.Result The magnitude of opportunistic infections was 39.6%. Major identified OIs was oral candidacies 23.2%, recurrent bacterial pneumonia 21.5%, Herpes zoster 6.3%, and Pulmonary Tuberculosis 6.0%.The magnitude of opportunistic associated with; older age [AOR=2.69, 95% CI: 1.33-5.43], No formal education [AOR=3.12, 95% CI: 1.06-9.25], Low monthly income [AOR=2.27, 95%CI:1.35-3.83], initial CD4 count less than 200 cells/mm3 [AOR=1.91, 95% CI:1.05-3.46), WHO clinical stage II [AOR=2.43, 95% CI:1.34-4.42] and stage III and IV [AOR=4.27, 95% CI: 2.12-8.59], had no extra medicine additional to ART (prophylaxis) had [AOR= 5.91, 95% CI: 3.31-10.56], who interrupt ART medicines [AOR=2.03, 95% CI: 1.09- 3.80] and Khat chewing [AOR=5.48, 95% CI: 2.32-12.96] when compared to their counterparts.Conclusions The overall magnitude of opportunistic infections was high when compared with other studies. Health officials and clinicians need to give attention on the strengthening of the provision if ART with prophylaxis on early-stage and adhrerence, implementation of the TB/HIV collaboration activity, and early initiation of ART to reduce opportunistic infections.

scholarly journals Determinants of Survival Among HIV/AIDS Patients With The Second-Line Antiretroviral Therapy In Henan Province of China 

2021 ◽  
Author(s):  
Yantao Jin ◽  
Miao Zhang ◽  
Yan-min Ma ◽  
Hui-jun Guo ◽  
Peng-yu Li ◽  
...  
Keyword(s):  
Cohort Study ◽  
Antiretroviral Therapy ◽  
Retrospective Cohort Study ◽  
Highly Active Antiretroviral Therapy ◽  
Retrospective Cohort ◽  
Cox Regression ◽  
Second Line ◽  
Aids Patients ◽  
Cd4 Cell Count ◽  
Hiv Aids

Abstract Background: To estimate the survival and effectors of mortality among HIV/AIDS patients switch to second-line highly active antiretroviral therapy (ART) in rural China.Methods: A three years’ retrospective cohort study was conducted and HIV/AIDS patients switched to the second-line ART between January 2009 to December 2014 enrollment. The data collected from medical records and analysis using Kaplan-Meier statistics and COX regression models.Findings: A total of 2883 HIV/AIDS participants followed up for 8445 person-years, 183 (6.5%) died, 14(0.5%) lost follow-up and the mortality rate 2.17/100 person-years. After adjusting other confounding factors by multivariable COX regression, age older than 50 years (HR,3.37; 95%CI, 1.92-5.92), Traditional Chinese medicine therapy (HR,0.48; 95%CI, 0.33-0.71), CD4 cell count littler than 200 cells/μl (HR,2.97; 95%CI, 1.90-4.64), AST or ALT higher than 50 u/L (HR,1.55; 95%CI, 1.15-2.11) were each independently associated with mortality among HIV/AIDS patients switch to second-line ART.Conclusions: Our retrospective cohort study indicates that mortality among HIV/AIDS patients switch to second-line ART lower than most other studies. However, the limitations of a retrospective cohort could have biased the study, so prospective studies should be carried out to confirm our primary results. The result of our study suggest that Chinese therapy was potential treatment for HIV/AIDS patients.

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