scholarly journals ANGKA BANDING APO B/APO A-I PADA GEJALA KORONER AKUT

Author(s):  
Sienny Linawaty ◽  
JB. Suparyatmo ◽  
Tahono Tahono

Coronary Artery Disease has a high prevalence and is frequently occurred and associated with the high mortality and morbidity. Dyslipidemia is one of the risk factors of Coronary Heart Disease (CHD). ApoB contained in very low-density lipoproteins (VLDL), intermediate-density lipoproteins (IDL), LDL and small dense LDL (sd-LDL), with one molecule of apoB in each particle. Apo A-I is the major apolipoprotein in HDL particles. The ratio of apoB/apoA-I is a balance between apoB-containing particles and potentially atherogenic apoA-I that is antiaterogenik. This study is carried to know the determination whether there are differences between apoB/ apoA-I ratio in patients dyslipidemia with ACS and non ACS. The research used a cross-sectional study design with patients dyslipidemia subjects suffering Acute Coronary Syndrome (ACS) and non ACS who enter to the Laboratory of Pathology Clinic at Dr. Moewardi Hospital between July and November 2011. To determine the pattern of data distribution, the researchers used Kolmogorov Smirnov test. For the analysis of differences in mean apoB/apoA-I ratio in the two population groups is used the T test, using a computer program, with the significance level p<0.05, 95% confidence interval. From 74 samples examined the mean age is 56.42 year old. This patients consisted of 33 males (44.6%) and 41 women (55.4%). All subjects are grouped into two groups, dyslipidemia ACS and non dyslipidemia ACS. The results showed apoB/apoA-I ratio significantly different in patients with dyslipidemia with ACS and non ACS. The mean apoB/apoA-I ratio of women and men subjects in both groups, including groups at high risk of myocardial myokard and higher than the cut-off ratio of apoB/ apoA-I (men 0.9 and women 0.8). It can be concluded that the apoB/apoA-I ratio of women and men subjects in both groups, included the high risk category for infarct myokard although lipid abnormalities are still not demonstrated to the risk of infarct myokard.

Author(s):  
Basavaraj S. Mannapur ◽  
Bhagyalaxmi S. Sidenur ◽  
Ashok S. Dorle

Background: Diabetes is considered as a global emergency where a person dies from diabetes every 6 seconds and diabetes is seen on 1 in 11 adults. Identification of individuals who are at risk is very much necessary to prevent diabetes in India. IDRS could also help to detect people at risk of having prediabetes. The objective of the study were to estimate the prevalence of diabetes mellitus in the age group of >20 years in urban field practice area of S.N. Medical college, Bagalkot and to identify high risk subjects using Indian diabetes risk score (IDRS).Methods: A cross sectional study was done in urban field practice area of S.N. Medical College among adults >20 years of age with sample size of 207. Systematic random sampling was used to select the subjects. Data was collected using standardised questionnaire which included socio-demographic profile, standard glucometer was used to measure random blood glucose for all participants. IDRS was used to ascertain the risk of developing diabetes. Data was analysed using Pearson’s Chi square test and Fischer exact.Results: The overall prevalence of diabetes was 14.1%. Among 206 subjects, 4.8% were in low risk category. 39.6% and 55.1% were in moderate and high risk category respectively. Total of 11 subjects were newly diagnosed in our study. Among them 10 subjects were in the high risk category and 1 was in the low risk category. Sensitivity of IDRS was 90%, specificity 50%, positive predictive value 43.8% and negative predictive value 96.74%..Conclusions: This study estimates the usefulness of simplified Indian diabetes risk score for identifying high risk diabetic subjects in the community. It can be used routinely in commu­nity-based screening to find out high risk people for diabetes so that proper intervention can be done to reduce the burden of the disease. 


2021 ◽  
Vol 21 (suppl 2) ◽  
pp. 413-419
Author(s):  
Leopoldo Nelson Fernandes Barbosa ◽  
Monica Cristina Batista de Melo ◽  
Maria do Carmo Vieira da Cunha ◽  
Eliane Nóbrega Albuquerque ◽  
Juliana Monteiro Costa ◽  
...  

Abstract Objectives: to analyze the frequency of anxiety, stress and depression in Brazilians during the COVID-19 pandemic period. Methods: cross-sectional study conducted with Brazilians during the COVID-19 pandemic. Data collection was performed via an online electronic form containing self-reported sociodemographic and mental health variables using the Depression, Anxiety and Stress Scale (DASS-21) using the snow-ball sampling technique. For the whole study, a significance level of 0.05 was considered, except for the application of the stepwise method, which considered a level of 0.2. Results: 1,775 people responded the survey, mostly women (78.07%), white (58.13%), single (45.78%), currently working (63.74%). 32.03% received psychotherapy or some type of emotional support before the pandemic, 19.03% had some psychiatric diagnosis and 8.49% started some support after the beginning of the pandemic. The mean scores investigated by the DASS-21 scale were 5.53869 for depression, 4.467334 for anxiety and 8.221202 for stress. Conclusions: during the COVID-19 pandemic, sociodemographic and mental health characteristics were mapped and in Brazilians and the symptoms of anxiety, depression and stress were identified mainly in women, single people, who did not currently work and already had some previous mental health symptom.


Author(s):  
Mahnaz Hatami ◽  
Habib Khanzadeh ◽  
Mohammad Hossein Lotfi kamran

Introduction: According to the need to know about patient satisfaction in Shahid Sadoughi Dentistry School of Yazd, this study was conducted to evaluate the satisfaction of patients referred to the Department of Restorative, Endodontics, Periodontology, Prosthodontics and Comprehensive Therapy in 2018. Methods: In this descriptive cross-sectional study, the satisfaction rate of 267 patients referred to the School of Dentistry in 5 sections (Periodontics, Endodontics, Restorative, Prosthodontics, and Comprehensive Therapy) at the end of treatment was evaluated using a Dental Satisfaction Questionnaire (DSQ). The questionnaire contained 19 questions in 3 areas: pain, access, and quality of treatment. Data were analyzed by SPSS software version 17 and also t-test and ANOVA. The significance level in this study was considered 0.05. Results: The mean age of patients in this study was 31. 9 ± 11.4 that 63.7% of them were female. According to the results, the mean total score of satisfaction in the studied patients was 68.8 ± 9.2 from 100, and the mean score in area of pain, access, and quality of treatment was 63.9, 65.9 and 71.7, respectively. There was no significant relationship between patients' satisfaction and age, sex, place of residence and different departments of the faculty (P≥0.05), there was only a significant increase in the field of pain satisfaction with increasing age (P = 0.014). Conclusion: The average satisfaction score of patients referring to Shahid Sadoughi Dentistry School of Yazd in the five sections was 68.8 and was desirable. Considering the degree of satisfaction, more effort is needed to increase the satisfaction of patients.


2020 ◽  
Vol 3 (1) ◽  
pp. 17-22
Author(s):  
Nur Wulan Nugrahani ◽  
Arie Udijono ◽  
Lintang Dian Saraswati ◽  
Arie Wuryanto

High-risk behavior placed inmates to be one of certain population to be vulnerable to sexually-transmitted infections (STI) due to the discontinuity of sexual needs in imprisonment. The purpose of this study is to describe the history of STIs-risked sexual behavior of inmates before and during imprisonment. This research was an observational study with a cross sectional study design. The samples were 100 male inmates in Semarang Class I Penitentiary. Univariate data analyzed and presented in frequency distribution. Characteristics of respondents in this study include the majority of respondents aged less than 40 years (70%), completed high school (42%), and married (48%). Sexual orientation before and during imprisonment were all heterosexual (100%). Historical description of STIs-risked sexual behavior with a high risk category were 53%, while during imprisonment were 71%. Based on sexual behavior in prison, 54% doing masturbation involving genital stimulation and pornography, 13% touching intimate parts in the visiting room, 5% had intercourse with the opposite sex in prisons. This findings implied that the sexual needs of inmates in prison are real and need to be channeled in a healthy manner.


2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Rodrigo Dias Nunes ◽  
Amanda De Vasconcelos Mapelli ◽  
Nazaré Otília Nazário ◽  
Eliane Traebert ◽  
Mayara Seemann ◽  
...  

Objetivo: O estudo objetiva conhecer os fatores associados à realização da episiotomia no parto vaginal. Metodologia: Estudo transversal envolvendo 330 partos, de janeiro/2012 a dezembro/2013. Estudou-se a associação das variáveis independentes com a realização da episiotomia por meio de cálculo de razões de prevalência e seus respectivos intervalos de confiança, com nível de significância p < 0,05. Resultados: Na amostra estudada, 224 (67,9%) pacientes não realizaram episiotomia e 106 (32,1%) realizaram o procedimento. A idade média foi de 22,9 (± 5,9) anos e a episiotomia foi mais realizada naquelas com idade inferior a 20 anos [RP 1,61 (IC 95% 1,15; 2,25)] (p = 0,005). As mulheres com mais de 8 anos completos de estudo foram significativamente mais submetidas à episiotomia que as demais [RP 2,34 (IC 95% 1,70; 3,22)] (p < 0,001). Conclusão: A realização da episiotomia nesta população ocorreu com maior prevalência nas parturientes mais jovens e com maior escolaridade.Descritores: Episiotomia; Fatores associados; Parto vaginalEVALUATION OF THE DETERMINANT FACTORS TO EPISIOTOMY IN VAGINAL DELIVERYObjective: This study aims to evaluate the factors associated with its performance in vaginal delivery. Methodology: This is a cross-sectional study carried out with 330 births, from January / 2012 to December / 2013. The association of the independente variables with episiotomy was calculated by prevalence ratios and their respective confidence intervals, with significance level p < 0.05. Results: In the studied sample, 224 (67.9%) patients did not undergo episiotomy and 106 (32.1%) had the procedure. The mean age was 22.9 ± 5.9 years and the episiotomy was more frequently performed in those younger than 20 years old [PR 1.61 (95% CI 1.15; 2.25)] (p = 0.005). Women with more than 8 years of education were significantly more likely to undergo episiotomy than the others [PR 2.34 (95% CI 1.70; 3.22)] (p < 0.001). Conclusion: The episiotomy, in this population, occured more likely in younger and more educated parturients.Descriptors: Episiotomy; Associated factors; Vaginal birthEVALUACIÓN DE LOS FACTORES DETERMINANTES A LA REALIZACIÓN DE LA EPISIOTOMÍA EN EL PARTO VAGINALObjetivo: El estudio tiene como objetivo conocer los factores asociados a la realización de la episiotomía en el parto vaginal. Metodología: Estudio transversal que involucra 330 partos, de enero/2012 a diciembre/2013, para la asociación de las variables independientes con la episiotomía por razones de prevalencia y sus respectivos intervalos de confianza, con p <0,05. Resultados: En la muestra, 224 (67,9%) pacientes no realizaron episiotomía y 106 (32,1%) realizaron el procedimiento. La edad media fue de 22,9 (± 5,9) años y la episiotomía fue más realizada en aquellas con edad inferior a 20 años [RP 1,61 (IC 95% 1,15, 2,25)] (p = 0,005) ). Las mujeres con más de 8 años completos de estudio fueron significativamente más sometidas a la episiotomía que las demás [RP 2,34 (IC 95% 1,70; 3,22)] (p <0,001). Conclusión: La realización de la episiotomía ocurrió con mayor prevalencia en las parturientas más jóvenes y con mayor escolaridad.Descriptores: Episiotomía; Factores asociados; Parto vaginal


Author(s):  
Romuald Randriamahavonjy ◽  
Rosa L. Tsifiregna ◽  
Zafitsara Z. Andrianirina ◽  
Hery R. Andrianampanalinarivo

Background: Pre-eclampsia is a human-pregnancy-specific disease defined as the occurrence of hypertension and significant proteinuria in a previously healthy woman on or after the 20th week of gestation. It is one of the leading causes of maternal and perinatal morbidity and mortality worldwide. The aim of this study is to determine the prevalence of pre-eclampsia and to evaluate its maternal and fetal outcomes in a rural area.Methods: This is a cross-sectional study carried out at the Bejofo Mahitsy hospital. It is a District Hospital Referral Center, which is located on the outskirts of the capital, 32 km from Antananarivo, Madagascar. This work was carried out during 24 months, from January 2014 to December 2016. We have included all hospitalized pregnant patients with SBP ≥140 or DBP ≥90mmHg, significant proteinuria> 300mg/24H with or without edema.Results: During this period, we recorded 97 cases of pre-eclampsia, frequency of 1.68%. The mean age of the parturient was 28 years old and 46.39% of the patients were primiparous. At the admission to the hospital, 37 (38,14%) did not show any particular signs. Concerning the severe high blood pressure, 47 pregnant patients (48,46%) had SBP greater than 160 mm Hg and 26 womens (26,80%) had DBP greater than 110 mm Hg. Caesarean section was the method of delivery widely adopted in 74.22 %. Maternal morbidity was represented by eclampsia in 21.65%, Retroplacentary Hematoma in 3% and HELLP syndrome in 4.12%. Fetal morbidity was important with 35% of premature newborns, 25.77% was small for gestational age and 12.37% was with neonatal asphyxia. Intra uterine fetal mortality was found in 11.34% and the perinatal mortality rate was 8.73%.Conclusions: There is a high frequency of pre-eclampsia in our setting and the consequences of pre-eclampsia for neonatal mortality and morbidity outcome are alarmingly high pre-eclampsia. Prevention necessarily involves quality prenatal follow-up such as screening, early and appropriate care of hypertension during pregnancy.


2020 ◽  
Vol 5 (1) ◽  
pp. e12-e12
Author(s):  
Maryam Derakhshan ◽  
Azar Baradaran ◽  
Faranak Kamrad ◽  
Amir Hossein Pezeshki ◽  
Amirreza Rafiei javazm

Introduction: The most common type of endocrine malignancy is thyroid cancer (TC). TC is the 7th, 14th, and 11th most common cancer in women, men, and both sexes, respectively. Objectives: The aim of this research was to establish the frequency of benign and malignant tumors in thyroid surgery specimens performed in Al-Zahra hospital in Isfahan from 2011 to 2017. Patients and Methods: This is a retrospective descriptive cross-sectional study. 1345 patients who underwent thyroid surgery were enrolled using census sampling. Data were analyzed using SPSS software (IBM statistics for windows, version 16) using descriptive statistics, mean, standard deviation, frequency, chi-square, and ANOVA. A significance level of less than 0.05 was analyzed. Results: Of 1345 participants, 237 (17.6%) were males, and 1108 (82.4%) were females. The mean age of benign patients was 46.48, malignant 39.31, and healthy patients for 37.50 years. Since the level of significance is less than 0.05, there is a significant relationship between the mean age of patients and the frequency of thyroid surgery specimens. The most prevalent benign and malignant thyroid tumors were goiter (76.8%) and papillary carcinoma (92.6%), respectively. Conclusion: The results showed that there was a significant relationship between age, gender, and benign and malignant type. Also, the most prevalent benign and malignant thyroid tumors were goiter and papillary, respectively.


Author(s):  
Willy Pangestu ◽  
Maria Loho ◽  
Freddy Wagey

Objective: To determine the correlation between C‐telopeptide with osteoporosis risk by using Osteoporosis Self Assessment Tools for Asian (OSTA) in postmenopausal women. Method: An analytic cross‐sectional study of 31 postmenopausal women in Prof. Dr. RD Kandou Hospital, Manado. Samples were collected through consecutive sampling. Data was analyzed using Pearson test with significance level of p>0.05. Result: Our sample consisted of 31 postmenopausal women. Mean OSTA score is ‐1.02K2.54. Sixteen women (51.61%) were deemed to have low risk, 8 women (25.81%) deemed to have moderate risk and 7 women (22.58%) deemed high risk based on the OSTA score. The mean C‐telopeptide plasma level of our sample is 0.52K0.25 􀁏g/l. We found plasma C‐telopeptide level and OSTA score were normally distributed. Correlation analysis using Pearson test identified a significant negative correlation between plasma C‐telopeptide level and OSTA score (r=‐0.768; p=0.001). Conclusion: There is a significant negative correlation between plasma C‐telopeptide level with risk of osteoporosis based on OSTA score in postmenopausal women. Keywords: OSTA score, plasma C‐telopeptide, postmenopausal women


2021 ◽  
Author(s):  
Oliver Okoth Achila ◽  
Nahom Fessahye ◽  
Samuel Tekle Mengstu ◽  
Naemi Tesfamariam Habtemikael ◽  
Wintana Yebio Werke ◽  
...  

Abstract Background: The objective of this study was to estimate the prevalence of dyslipidemias and associated factors in adults (≥35 to ≤ 85 years) living in Asmara, Eritrea. Methods: A total of 384 (144 (%) males and 242 (%) females, mean age ± SD, 68.06±6.16 years) respondents were randomly selected after stratified multistage sampling. The WHO NCD STEPS instrument version 3.1 questionnaire was used to collect data. Measurements/or analysis including anthropometric, lipid panel, fasting plasma glucose (FPG), and blood pressure (BP) were also undertaken. Results: The frequency of dyslipidemia in this population was disproportionately high (87.4%) with the worst affected subgroup in the 51-60 age band. The level of awareness was also low. In terms of individual lipid markers, the proportion were as follows: HDL-C (40 mg/dL men and 50 mg/dL females) (55.2%); TC ≥ 200 mg/d (49.7%); LDL≥130 mg/dL (44.8%); TG≥150 mg/dL (38.1%). The mean ± SD, for HDL-C, TC, LDL-C, non-HDL-C, and TG were 45.28±9.60; 205.24±45.77; 130.77±36.15; 160.22±42.09 and 144.5±61.26 mg/dl, respectively. Regarding NCEP ATP III risk criteria, 17.6%, 19.4%, 16.3%, 19.7%, and 54.7% were in high or very high-risk categories for TC, Non-HDL-C, TG, LDL-C, and HDL-C, respectively. Among all respondents, 59.6% had mixed dyslipidemias with TC+TG+LDL-C dominating. In addition, 27.3%, 28.04%, 23.0%, and 8.6% had abnormalities in 1, 2, 3 and 4 lipid abnormalities, respectively. In terms of Framingham CVD Risk scores, 12.7%, 2.8% were in the high risk and very high-risk strata. Further, the high burden of dyslipidemia coexisted with an equally high burden of abdominal obesity (71.8%), BMI≥25 kg/m2 (44.6%), dysglycemia (24.7%), hypertension (24.4%), and physical inactivity. Dyslipidemia was associated with employment status (ref: unemployed vs. employed, aOR 0.48, 95% CI 0.24–0.97, p=0.015) and self-employed (aOR 0.41, 95% CI 0.17–1.00, p=0.018); marital status (ref: not married vs married (aOR 2.35, 95% CI 1.19–4.66, p=0.009); increasing DBP (aOR 1.04 mmHg (1.00-1.09)=0.001) and increasing FPG (aOR 1.02 per 1 mg/dL, 95% CI 1.00–1.05, p=0.001). Conclusion: High frequency of poor lipid health may be a prominent contributor to the high burden of CVDs – related mortality and morbidity in Asmara, Eritrea. Consequently, efforts directed at early detection, and evidence-based interventions are warranted.


2021 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Mehdi Mirzaei-Alavijeh ◽  
Cyrus Jalili ◽  
Habibolah Khazaie ◽  
Saba Shahsavari ◽  
Negar Karimi ◽  
...  

Background: Motivation is defined as the development of an individual’s desire to succeed and participate in the activities in which success depends on personal effort and ability. Objectives: The present study aimed to evaluate the status of achievement motivation in university students. Methods: This cross-sectional study was conducted on 182 medical, dentistry, and pharmacology students at Kermanshah University of Medical Sciences (KUMS), Iran in 2018. The participants were selected via simple random sampling with a probability appropriate to the selected sample size. Data were collected using a self-report questionnaire. Data analysis was performed in SPSS version 16 using chi-square and t-test at the significance level of 95%. Results: The mean age of the participants was 21.14 ± 1.68 years (age range: 19 - 25 years). The mean score of achievement motivation was 77.64 ± 7.35, which indicated that the participants obtained 66.93% of the maximum score. In addition, 89.5% and 10.5% of the students had moderate and favorable achievement motivation, respectively. Achievement motivation was significantly correlated with age (P = 0.031), male gender (P = 0.022), and maternal education level (P = 0.018). Conclusions: According to the results, the achievement motivation of the majority of the KUMS students was moderate. Therefore, proper planning is required to improve the achievement motivation of these students.


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