scholarly journals Smoking Habit and Correlation with Hand Eczema in Healthcare Workers in the Time of COVID-19

2021 ◽  
Vol 6 (2) ◽  
pp. 100-102
Author(s):  
Anca E. Chiriac ◽  
Doina Azoicai ◽  
Uwe Wollina ◽  
Anca Chiriac ◽  
Cristian Podoleanu ◽  
...  
Keyword(s):  
Risk Factor ◽  
Healthcare Workers ◽  
Random Distribution ◽  
Smoking Habit ◽  
Hand Eczema ◽  
Additional Risk Factor ◽  
Additional Risk ◽  
The Past ◽  
Occupational Hand Eczema ◽  
The Moment

Abstract Background: Hand eczema, in time of COVID-19, is one of the most frequently diagnosed skin disorders in nurses. In this study, we sought to investigate whether smoking could be an additional risk factor for hand eczema in nurses during the COVID-19 pandemic. Method: Using a questionnaire about smoking details and hand eczema, we conducted a study among nurses involved in the frontline management of COVID-19 patients. A total of 1,000 questionnaires were sent out. The questionnaires were anonymous and based on self-reported answers, with no clinical examination or medical data evaluation. All nurses enrolled in the study were women, working in shifts for the last three months since the start of the COVID-19 pandemic. Results: Two-hundred forty-seven questionnaires were accepted for the study, after eliminating non-responders and nurses without hand eczema. The majority of nurses denied smoking (87.85%) in the past and at the moment of the study. Statistics related to years of smoking and occurrence of hand eczema showed no increase in the number of cases in correlation with the number of years of smoking. Similarly, a random distribution of cases of hand eczema was observed when compared to the number of cigarettes per day. Conclusion: Our data does not support the hypothesis that smoking is an independent risk factor for the development of occupational hand eczema during the COVID-19 pandemic.

scholarly journals L’importanza del vaccino anti Covid-19 nei pazienti affetti da malattia del rene policistico autosomico dominante dell’adulto (ADPKD)

2021 ◽  
Vol 33 ◽  
pp. 84-87
Author(s):  
Maria Teresa Sciarrone Alibrandi ◽  
Giancarlo Joli ◽  
Rodolfo F. Rivera ◽  
Elena Brioni ◽  
Romina Bucci ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Risk Factor ◽  
Kidney Disease ◽  
Kidney Injury ◽  
Point Of View ◽  
Additional Risk Factor ◽  
Additional Risk ◽  
The Moment ◽  
Clear Relation ◽  
Related Mortality

The SARS-CoV-2 (Covid-19) infection affected about 106 million people worldwide and the total amount of casualties now sits at a staggering 2 millions. Chronic Kidney Disease (CKD) emerged as the first risk factor in worst patients, not considering old age. Kidney disease and acute kidney injury have been correlated with a higher chance of death. This combination of CKD and higher Covid-19 related mortality requires immediate response from a prevention point of view at first and then from a therapeutic one. There is not a clear relation between Covid-19 and ADPKD. What can be inferred is the following: Covid uses the ACE2 receptors on cell membranes to “lock on” its target. It is well-established in fact that the RAAS is more active in ADPKD patients and it may represent an additional risk factor for these patients. At the moment three Covid-19 vaccines have been approved, and two of them have been already administered, such as Pfizer BioNTech and Moderna, sharing the same mechanism. AstraZeneca released a third option. All of them are completely safe and reliable, each one with its own feature. Therefore, considering how delicate ADPKD patients are, vaccination is strongly recommended.

scholarly journals Hypothesis: Is frequent, commercial jet travel by the general public a risk factor for developing cutaneous melanoma?

F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 620
Author(s):  
Harvey Arbesman
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Cutaneous Melanoma ◽  
General Public ◽  
Additional Risk Factor ◽  
Additional Risk ◽  
The Past ◽  
Airline Crew ◽  
Time Period ◽  
Increased Risk

Melanoma incidence has been increasing worldwide over the past 50 years and various risk factors have been identified. Interestingly, multiple studies have shown a multifold increased risk of developing melanoma in jet pilots and airline crew. There has also been a dramatic increase in the availability and frequency of jet travel by the general population during this time period.. Therefore, it is hypothesized that frequent commercial jet travel may represent an additional risk factor for the development of cutaneous melanoma in susceptible individuals of the general public.

HLA-DP variation as additional risk factor in IDDM

Diabetes ◽  
1990 ◽  
Vol 39 (7) ◽  
pp. 855-857 ◽  
Author(s):  
S. Easteal ◽  
M. R. Kohonen-Corish ◽  
P. Zimmet ◽  
S. W. Serjeantson
Keyword(s):  
Risk Factor ◽  
Additional Risk Factor ◽  
Additional Risk

Prevalence and prognostic impact of left ventricular systolic dysfunction after acute myocardial infarction

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
T.J Jernberg ◽  
E.O Omerovic ◽  
E.H Hamilton ◽  
K.L Lindmark ◽  
L.D Desta ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Myocardial Infarction ◽  
Atrial Fibrillation ◽  
Risk Factor ◽  
Reperfusion Therapy ◽  
Left Ventricular ◽  
Funding Source ◽  
Additional Risk Factor ◽  
Additional Risk

Abstract Background Left ventricular dysfunction after an acute myocardial infarction (MI) is associated with poor outcome. The PARADISE-MI trial is examining whether an angiotensin receptor-neprilysin inhibitor reduces the risk of cardiovascular death or worsening heart failure (HF) in this population. The aim of this study was to examine the prevalence and prognosis of different subsets of post-MI patients in a real-world setting. Additionally, the prognostic importance of some common risk factors used as risk enrichment criteria in the PARADISE-MI trial were specifically examined. Methods In a nationwide myocardial infarction registry (SWEDEHEART), including 87 177 patients with type 1 MI between 2011–2018, 3 subsets of patients were identified in the overall MI cohort (where patients with previous HF were excluded); population 1 (n=27 568 (32%)) with signs of acute HF or an ejection fraction (EF) <50%, population 2 (n=13 038 (15%)) with signs of acute HF or an EF <40%, and population 3 (PARADISE-MI like) (n=11 175 (13%)) with signs of acute HF or an EF <40% and at least one risk factor (Age ≥70, eGFR <60, diabetes mellitus, prior MI, atrial fibrillation, EF <30%, Killip III-IV and STEMI without reperfusion therapy). Results When all MIs, population 1 (HF or EF <50%), 2 (HF or EF <40%) and 3 (HF or EF <40% + additional risk factor (PARADISE-MI like)) were compared, the median (IQR) age increased from 70 (61–79) to 77 (70–84). Also, the proportion of diabetes (22% to 33%), STEMI (38% to 50%), atrial fibrillation (10% to 24%) and Killip-class >2 (1% to 7%) increased. After 3 years of follow-up, the cumulative probability of death or readmission because of heart failure in the overall MI population and in population 1 to 3 was 17.4%, 26.9%, 37.6% and 41.8%, respectively. In population 2, all risk factors were independently associated with death or readmission because of HF (Age ≥70 (HR (95% CI): 1.80 (1.66–1.95)), eGFR <60 (1.62 (1.52–1.74)), diabetes mellitus (1.35 (1.26–1.44)), prior MI (1.16 (1.07–1.25)), atrial fibrillation (1.35 (1.26–1.45)), EF <30% (1.69 (1.58–1.81)), Killip III-IV (1.34 (1.19–1.51)) and STEMI without reperfusion therapy (1.34 (1.21–1.48))) in a multivariable Cox regression analysis. The risk increased with increasing number of risk factors (Figure 1). Conclusion Depending on definition, post MI HF is present in 13–32% of all MI patients and is associated with a high risk of subsequent death or readmission because of HF. The risk increases significantly with every additional risk factor. There is a need to optimize management and improve outcomes for this high risk population. Figure 1 Funding Acknowledgement Type of funding source: Private company. Main funding source(s): Novartis

scholarly journals Socio-economic impact in the late diagnosis of retinopathy of prematurity

2016 ◽  
Vol 11 (1) ◽  
pp. 45-48
Author(s):  
Daniela POPESCU ◽  
◽  
Dumitru MATEI ◽  
◽  
◽  
...  
Keyword(s):  
Risk Factor ◽  
Human Resources ◽  
Retinopathy Of Prematurity ◽  
Social Impact ◽  
Treatment Programs ◽  
Additional Risk Factor ◽  
Fundus Examination ◽  
Additional Risk ◽  
Simple Process ◽  
Socio Economic Impact

Retinopathy of prematurity (ROP) represents a determinate cause of blindness in children that could be avoided. Blindness due to ROP and the stage of it when its being diagnosed is mostly determined by: socioeconomic degree of country development; availability of the screening in neonatal care; gestational age and hospital screenings; treatment programs available at any given time in the country; screening and treatment costs (material and human resources). ROP is the number one cause of blindness in Romania at the time being. Early discovery decreases exponentially the chances of blindness onset. Low birth weight (LBW), fewer than 1,500 g, represents an additional risk factor together with the degree of prematurity. Mandatory screening both during hospitalization as well as in the first 4-6 weeks after birth may avoid a major social problem. It is a simple process – eye exam with fundus examination – and it depends entirely on the availability, consistency and seriouseness of the parents. Thus a major social impact with disastrous consequences could be avoided.

Hematogenous thrombophilia as an additional risk factor for cerebral circulation disorders

2021 ◽  
Author(s):  
И.В. Куртов ◽  
С.П. Кривова ◽  
Р.К. Хайретдинов ◽  
И.Л. Давыдкин
Keyword(s):  
Risk Factor ◽  
Factor Viii ◽  
Blood Coagulation ◽  
Genetic Polymorphisms ◽  
Additional Risk Factor ◽  
Factor Viii Level ◽  
Aged Patients ◽  
Additional Risk ◽  
Viii Level ◽  
The Impact

Введение. Гематогенная тромбофилия служит дополнительным фактором риска нарушений мозгового кровообращения (НМК). Цель исследования: изучить влияние повышенного уровня фактора VIII и нарушений в системе фибринолиза на НМК у пациентов с сочетанной патологией системы свертывания крови. Материалы и методы. Обследовано 20 пациентов с перенесенными ишемическими инсультами в возрасте от 36 до 56 лет. Определяли показатели плазменного, тромбоцитарного звеньев гемостаза, системы фибринолиза, а также генетические полиморфизмы системы гемостаза. Результаты. У всех пациентов выявлены различные сочетания генетических полиморфизмов, связанных с изменениями антикоагулянтного звена гемостаза, а также дефекты системы фибринолиза и коагуляционного звена гемостаза, что является дополнительным фактором риска НМК. Заключение. У пациентов молодого и среднего возраста, перенесших острое НМК по ишемическому типу, необходимо исследование системы свертывания крови, включающее определение содержания фактора VIII в крови, показателей системы фибринолиза и уровня гомоцистеина. Background. Hematogenous thrombophilia is an additional risk factor for cerebral circulatory disorders (ССD). Objectives: to study the impact of increased factor VIII level and disturbances of fibrinolysis system on ССD in patients with combined pathology of blood coagulation. Patients/Methods. We examined 20 patients with ischemic strokes aged from 36 to 56 years. The parameters of plasma hemostasis, platelet function, fibrinolysis system, as well as the genetic polymorphisms of hemostasis system were determined. Results. All patients had different combinations of genetic polymorphisms associated with anticoagulant hemostasis changes, as well as defects in fibrinolysis system and coagulation hemostasis that is an additional risk factor for ischemic stroke. Conclusions. In young and middle-aged patients with history of acute ischemic ССD, it is necessary to study blood coagulation, including the determination of blood factor VIII level, fibrinolysis system parameters and homocysteine content.

scholarly journals Immunoglobulin free light chains and solitary plasmacytoma of bone

Blood ◽  
2006 ◽  
Vol 108 (6) ◽  
pp. 1979-1983 ◽  
Author(s):  
David Dingli ◽  
Robert A. Kyle ◽  
S. Vincent Rajkumar ◽  
Grzegorz S. Nowakowski ◽  
Dirk R. Larson ◽  
...  
Keyword(s):  
Risk Factor ◽  
Protein Level ◽  
M Protein ◽  
Solitary Plasmacytoma ◽  
Additional Risk Factor ◽  
Time To Progression ◽  
Additional Risk ◽  
Risk Stratification Model ◽  
Risk Of Progression ◽  
Solitary Bone Plasmacytoma

AbstractAn abnormal serum immunoglobulin free light chain (FLC) ratio at diagnosis may identify risk of progression to myeloma in patients with solitary bone plasmacytoma (SBP). In the cohort of 116 patients, 43 have progressed to myeloma, with a median time to progression of 1.8 years. The FLC ratio was determined in all 116 patients on serum collected at time of diagnosis and was abnormal in 54 patients (47%). An abnormal FLC ratio was associated with a higher risk of progression to myeloma (P = .039). The risk of progression at 5 years was 44% in patients with an abnormal serum FLC ratio at diagnosis compared with 26% in those with a normal FLC ratio. One to 2 years following diagnosis, a persistent serum M protein level of 5 g/L (0.5 g/dL) or higher was an additional risk factor for progression. A risk stratification model was constructed using the 2 variables of FLC ratio and M protein level: patients with a normal FLC ratio at baseline and M protein level less than 5 g/L (0.5 g/dL) at 1 to 2 years following diagnosis (low risk, n = 31); with either risk factor abnormal (intermediate risk, n = 26); and with both an abnormal FLC ratio and M protein level of 5 g/L (0.5 g/dL) or higher (high risk, n = 18). The corresponding progression rates at 5 years were significantly different in the low, intermediate, and high groups: 13%, 26%, and 62%, respectively (P < .001).

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