scholarly journals Renal Vascular Lesions in Patients with Diabetes Mellitus

2013 ◽  
Vol 20 (1) ◽  
pp. 21-27
Author(s):  
Mirela-Simona Nicodim ◽  
Mariana Aşchie ◽  
Doina Catrinoiu ◽  
Laurenţiu-Tony Hangan

Abstract Background and Aims. Patients with diabetes mellitus, especially type 2 diabetes, have often a multifactorial renal impairment. The aim of this study was to correlate renal vascular lesions occurring in patients with diabetes mellitus with clinical and laboratory parameters. Material and method. We performed a retrospective study on a sample of 127 patients with diabetes mellitus, who died in hospital. Data from necropsies were correlated with the clinical and laboratory data collected from the medical records of these patients. Results. Renal vascular lesions were frequently found in patients from the study group. The most common were nephroangiosclerosis lesions, which correlated with age, diabetes duration, systolic blood pressure and mean fasting glucose. Conclusions. Most patients in the study group had multiple cardiovascular risk factors (advanced age, dyslipidemia, hypertension) that explain the high prevalence of renal vascular lesions.

Author(s):  
Himanshu Patel ◽  
Dhiren Shah

Background: To determine the prevalence of HU in Indian subjects attending the HU screening camps and in subjects with type 2 Diabetes Mellitus (T2DM), Hypertension (HTN), and T2DM+HTN.Methods: This was a retrospective, non-interventional study where medical records of subjects attending HU screening camps across 592 locations in India, between June 2017 to May 2018, were analyzed.Results: A total of 197097 subjects (T2DM: 19.69%; HTN: 14.08%; T2DM+HTN: 21.60%) attended the screening camps. Mean age of the study participants was 48.43±13.38 years (Male: 53.80%). A total of 48606(24.66%) subjects had HU. In the overall population, a higher proportion of subjects with T2DM + HTN (7.36%) had HU in comparison to subjects with T2DM (5.63%) and HTN (4.25%) alone. Similar results were reported when the data was evaluated only in HU subjects (T2DM+HTN: 29.85%; T2DM: 22.82%; HTN: 17.22%). Proportion of HU subjects increased with age, with the maximum prevalence evident in subjects aged >50 years (12.94%), followed by 30-50 years (10.65%) and <30 years (1.07%). Gender-wise, a slightly higher proportion of males (14.13%) were found to be hyperuricemic than females (10.53%). Higher proportion of subjects with disease (T2DM and/or HTN) duration of 2-5 years were found to be hyperuricemic in comparison with subjects with disease duration of >5 years or <2 years. Similar results were reported when the data was evaluated in the overall HU subjects and by indication.Conclusions: Authors observed a high prevalence of HU among subjects attending HU camps and those with associated comorbidities. The prevalence of HU was higher in males and has an increasing trend with age. Furthermore, the prevalence of HU was observed to be higher in subjects with 2-5 years of duration of T2DM and/or HTN.


2017 ◽  
Vol 14 (2) ◽  
pp. 22
Author(s):  
Meiby Lorena Rojas-Castañeda ◽  
Rosa Del Carmen Coral-Ibarra ◽  
Luz Dalila Vargas-Cruz

Objetivo: Analizar el perfil sociodemográfico, condiciones de salud y atención a personas con diabetes, a partir de la revisión de historias clínicas. Materiales y Métodos: estudio descriptivo transversal. La población fue de 821 historias clínicas de pacientes con diabetes mellitus. En total la muestra fue de 230 historias clínicas por método aleatorio simple. Se utilizó el instrumento Impacto en la Condición de Salud y Calidad de Vida de las Atenciones de Salud en Pacientes Diabéticos Tipo 2 de Macul, que evalúa el perfil sociodemográfico, las condiciones de salud y el tipo de atención otorgada. Resultados: 39 % de los pacientes presentó el valor de la última hemoglobina glicosilada mayor de 12 %, el 41,3 % no presentó ningún riesgo de pie diabético, 46,9 % tuvo diagnóstico de obesidad y el 23,9 % presentó sobrepeso. El porcentaje de cumplimiento de citas al mes por parte del médico y la enfermera fue del 100 %, a diferencia del control por parte de la nutricionista que debe realizase cada 6 meses, sólo se registró un cumplimiento del 71,7 %. No se encontró relación estadísticamente significativa entre asistencia al programa con adherencia al tratamiento, o con compensación de la enfermedad. Conclusiones: los pacientes con diabetes a pesar de estar en un programa de atención integral, no tienen un óptimo control glicémico, lo cual sugiere la revisión del cumplimiento del régimen terapéutico por parte de los profesionales de la salud para prevenir complicaciones que se puedan presentar a corto, mediano o largo plazo.PALABRAS CLAVE: atención a la salud, complicaciones crónicas, diabetes mellitus tipo 2, enfermedad crónica.SOCIO-DEMOGRAPHIC PROFILE, HEALTH CONDITIONS AND ATTENTION TO PEOPLE WITH DIABETES.ABSTRACT Objective: To analyze the socio-demographic profile, health conditions and attention to people with diabetes from a review of medical records. Materials and Methods: cross-sectional descriptive study. The population was of 821 medical records of patients with diabetes mellitus. In total the sample was of 230 medical records through a simple aleatory method. The Impact instrument was used in the Health Condition and Life Quality of the Health Care in Diabetic Patients Type 2 from Macul, that evaluates the socio-demographic profile, the health conditions and the type of attention given. Results: 39% of the patients presented the value of the last glycosylated hemoglobin greater than 12%, 41,3% did not present any risks of diabetic foot, 46,9% had an obesity diagnose and 23,9% presented overweight. The doctor and the nurse percentage of compliance of appointments per month was 100%, as opposed to the control by the nutritionist that must be performed every 6 months, only a of 71,1% of compliance was registered. A statistically significant relationship was not found between compliance to the program and treatment adherence, or with compensation for the disease. Conclusions: patients with diabetes despite of being in a program of comprehensive care, do not have an optimal glycemic control, which suggests a review of the compliance of the therapeutic regime by the health professionals to prevent complications that may occur in a short, medium, or long term.KEYWORDS: health care, chronic complications, diabetes mellitus type 2, chronic disease. PERFIL SÓCIO DEMOGRÁFICO, CONDIÇÕES DE SAÚDE E CUIDADOS PARA AS PESSOAS COM DIABETESRESUMO Objetivo: Analisar o perfil sócio demográfico, condições de saúde e cuidados para as pessoas com diabetes a partir da revisão de histórias clínicas. Materiais e Métodos: estudo descritivo transversal. A população foi de 821 historias clínicas de pacientes com diabetes mellitus. Em total a amostra foi de 230 historias clínicas por método aleatório simples. Utilizou-se o instrumento Impacto na Condição de Saúde e Qualidade de Vida das Assistências Médicas em Pacientes Diabéticos Tipo 2 de Macul, que avalia o perfil sócio demográfico, as condições de saúde e o tipo de atendimento recebido. Resultados: 39% dos pacientes apresentaram o valor da última hemoglobina glicada (Hb A1c) maior de 12%, o 41,3% não apresentou nenhum risco de pé diabético, 46,9% tiveram diagnóstico de obesidade e o 23,9% apresentaram excesso de peso. A porcentagem de cumprimento de consultas ao mês por parte do médico e a enfermeira foi do 100%, a diferença do controle por parte da nutricionista que deve realizar-se a cada 6 meses, apenas registrou-se um cumprimento do 71,7%. Não se encontrou relação estatisticamente significativa entre assistência ao programa com aderência ao tratamento, ou com compensação da doença. Conclusões: os pacientes com diabetes a pesar de estar num programa de atendimento integral, não tem um óptimo controle glicémico, o qual sugere a revisão do cumprimento do regime terapêutico por parte dos professionais da saúde para prevenir complicações que se possam apresentar a curto, médio ou longo prazo. Palavras-chave: assistência médica, complicações crónicas, diabetes mellitus tipo 2, doença crónica.


2002 ◽  
Vol 49 (6) ◽  
pp. 11-16
Author(s):  
Ye. V. Surkova ◽  
M. Yu. Drobizhev ◽  
O. G. Melnikova ◽  
T. A. Zakharchuk ◽  
I. I. Dedov

The fact that there is a high prevalence of depressions among patients with diabetes mellitus (DM) is well known. However, the relationships between the nosological entities of depressions and the clinical characteristics of DM are little studied. The study was undertaken to search for such relationships. A hundred and fifty outpatients with DM (out of them 38 males, Type 2 DM was diagnosed in 102 patients) the median age was 54.0 years (25 and 75 percentiles: 43.0-61.5), the median duration of diabetes was 7.2years (2.0-15.0); the median level of HbAlc was 8.6% (7.49.7%). Depression was revealed in 50 (33%) patients. Their comparison with patients without depression indicated that there was no association with the main clinical characteristics of MD (the type and duration of the disease, the prevalence of acute and chronic complications, insulin therapy). At the same time, a comparison of three groups of patients with the major clinical forms (nosogenic, cyclothymic, and dysthymic) of diagnosed depression by using x2 revealed the following associations: between DM-1 and cyclothymic depression and between DM-2 and nosogenic and dysthymic depression (р = 0.01). Cyclothymic and dysthymic depression showed no associations with clinical characteristics of DM. The prevalence of nosogenic depression was significantly higher in patients with a history of second-three grade diabetic retinopathy (p = 0.02), arterial hypertension (p = 0.001), proteinuria (p = 0.02), myocardial infarction (p = 0.04), and foot ulcerative defects (p = 0.04). The results show that nosogenic depression are mental responses to the severe course of DM, namely to the severity of micro- and macrovascular complications. The associations between the types of DM and the clinical types of depression -cyclothymia and dysthymia - await further study. Overall general predisposition may be discussed as a possible explanation.


2017 ◽  
Vol 98 (3) ◽  
pp. 334-337
Author(s):  
V V Kir’yanova ◽  
N V Vorokhobina ◽  
Z Kh Makhramov

Aim. To evaluate the effectiveness of bioresonance therapy use in complex treatment of patients with diabetes mellitus type 2. Methods. The treatment scheme including bioresonance therapy is offered for patients with diabetes mellitus type 2. All 413 patients were assigned to 3 comparable groups: the study group included 198 patients, control group - 72 patients, placebo group - 143 patients. Duration of diabetes in the study group was 5.47±0.37 years, in control group - 4.03±0.46 years, in placebo group - 4.97±0.39 years. All patients were treated according to the traditional scheme of treatment of type 2 diabetes. The study group in addition to pharmacotherapy received bioresonance therapy. Control group received only drug treatment and placebo group received drug therapy and bioresonance simulation procedures. All patients were checked for glycated hemoglobin, fasting plasma glucose, blood glucose 2 hours after a meal, urine glucose, and body mass index on admission and 3 months after treatment. Results. Results of glycated hemoglobin, fasting plasma glucose, blood glucose 2 hours after a meal, urine glucose, and body mass index revealed that initially studied parameters in all three groups were high. After the bioresonance therapy in complex treatment of patients with diabetes type 2 in the study group all studied parameters were statistically significantly lower compared to control and placebo groups. Conclusion. The obtained results indicate the effectiveness of bioresonance therapy use in complex treatment of patients with diabetes mellitus type 2.


Author(s):  
Larisa Dmitrievna Popovich ◽  
Svetlana Valentinovna Svetlichnaya ◽  
Aleksandr Alekseevich Moiseev

Diabetes – a disease in which the effect of the treatment substantially depends on the patient. Known a study showed that the use of glucometers with the technology of three-color display of test results facilitates self-monitoring of blood sugar and leads to a decrease in glycated hemoglobin (HbAlc). Purpose of the study: to modeling the impact of using of a glucometer with a color-coded display on the clinical outcomes of diabetes mellitus and calculating, the potential economic benefits of reducing the hospitalization rate of patients with diabetes. Material and methods. Based on data from two studies (O. Schnell et al. and M. Baxter et al.) simulation of the reduction in the number of complications with the use of a glucometer with a color indication. In a study by O. Schnell et al. a decrease of HbA1c by 0.69 percent is shown when using the considered type of glucometers, which was the basis of the model. Results. In the model, the use of a glucometer with a color-coded display for type 1 diabetes led to a decrease in the total number of complications by 9.2 thousand over 5 years per a cohort of 40 thousand patients with different initial levels of HbA1c. In a cohort of 40 thousand patients with type 2 diabetes, the simulated number of prevented complications was 1.7 thousand over 5 years. When extrapolating these data to all patients with diabetes included in the federal register of diabetes mellitus (FRD), the number of prevented complications was 55.4 thousand cases for type 1 diabetes and 67.1 thousand cases for type 2 diabetes. The possible economic effect from the use of the device by all patients with a diagnosis of diabetes, which are included in the FRD, estimated at 1.5 billion rubles for a cohort of patients with type 1 diabetes and 5.3 billion rubles for patients with type 2 diabetes. Conclusion. Improving the effectiveness of self-monitoring, which is the result of the use of glucometers with color indicators, can potentially significantly reduce the incidence of complications in diabetes and thereby provide significant economic benefits to society.


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