scholarly journals Evaluation of Nasal Decongestants by Literature Review

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Stasa Petkovic ◽  
Ivana Maletic ◽  
Sonja Djuric ◽  
Ninoslava Dragutinovic ◽  
Olivera Milovanovic
Keyword(s):  
Blood Vessels ◽  
Viral Infections ◽  
Good Effect ◽  
Self Medication ◽  
Time Intervals ◽  
Over The Counter ◽  
Nasal Sprays ◽  
Nasal Decongestants ◽  
Safety Precaution ◽  
Seasonal Allergies

Abstract Over-the-counter drugs are medicines that are available to consumers without a prescription. The most common оver - the-counter preparations in self - medication are nasal decongestants that can be used systemically or locally in the form of drops or nasal sprays. The most common indications for nasal decongest-ants are viral infections and allergic conditions in order to alleviate the symptoms so it is necessary to inform the users about the type of drug, the active substance it contains and the correct dosage regimen. Given their availability and the prevailing safety precaution, these preparations can lead to numerous prolonged conditions and complications. The mechanism of action of nasal decongestants is based on the reduction of blood vessels’ swelling in the nose, which helps the opening of the airway. As a result, most nasal decongestants cause vasoconstriction (narrowing of blood vessels). There are nasal decongestants that block histamine and have a good effect on people who suffer from seasonal allergies. Availability (free sale) and prolonged use of the decongestant lead to a decrease in the sensitivity of the alpha receptor, which leads to the need to increase the dose at shorter time intervals to achieve the same effect. As a consequence, patients use excessive, uncontrolled doses of nasal decongestants, which is a public problem and warns of the necessity of identification and the taking of measures to prevent their uncontrolled procurement and use.

scholarly journals Future Pharmacists’ Opinions on the Facilitation of Self-Care with Over-the-Counter Products and Whether This Should Remain a Core Role

Pharmacy ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 132
Author(s):  
Lezley-Anne Hanna ◽  
Alana Murphy ◽  
Maurice Hall ◽  
Rebecca Craig
Keyword(s):  
Emergency Contraception ◽  
Self Care ◽  
Pharmacy Students ◽  
Single Institution ◽  
Self Medication ◽  
Over The Counter ◽  
Otc Medicines ◽  
Practice Methods ◽  
Identifiable Data

Background: The aim was to investigate pharmacy students’ views on the role of the pharmacist in facilitating self-care with over-the-counter (OTC) medicines, particularly in light of new roles, and establish personal practice. Methods: Final year pharmacy students at Queen’s University Belfast were invited to participate. Data were collected via a pre-piloted questionnaire, distributed at a compulsory class (only non-identifiable data were requested). Descriptive statistics were performed, and non-parametric tests were employed for inferential statistical analysis (responses by gender). Results: The response rate was 87.6% (78/89); 34.6% (27/78) males and 65.4% (51/78) females. Over a third [34.6% (27/78)] reported using OTC medicines about once a month. All appreciated the importance of an evidence-based approach to optimize patient care. Most [(96.2% (75/78)] deemed OTC consultations should remain a fundamental responsibility of pharmacists and 69.2% (54/78) thought OTC consultations have the potential to be as complex as independent pharmacist prescribing. Females felt more confident recommending OTC emergency contraception than males (p = 0.002 for levonorgestrel and p = 0.011 for ulipristal acetate). Many [61.5% (48/78)] considered more medicines should not be deregulated from prescription-only status. Conclusions: Data from this single institution suggests that enabling self-medication is an important part of practice but there were confidence issues around deregulations.

scholarly journals Public perception of community pharmacists in South Africa: a preliminary study

2006 ◽  
Vol 11 (3) ◽  
Author(s):  
Suzanne Bornman ◽  
Ilse Truter ◽  
Daniel JL Venter
Keyword(s):  
South Africa ◽  
Full Text ◽  
Public Perception ◽  
Community Pharmacists ◽  
Community Pharmacies ◽  
Self Medication ◽  
Over The Counter ◽  
Preliminary Study

This survey forms part of a study undertaken to identify and quantify the community pharmacist’s involvement in the use of non-prescription/over-the-counter (OTC) medicine/self-medication in community pharmacies throughout South Africa. Opsomming Hierdie opname vorm deel van ‘n studie wat onderneem word om die gemeenskapsapteker se betrokkenheid in die gebruik van nie-voorskrif/oor-die-toonbank medikasie/ selfmedikasie in gemeenskapsapteke in Suid Afrika te identifiseer en te kwantifiseer. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

scholarly journals RESEARCH ON SELF MEDICATION: A HYPE OR A HOPE? A LITERATURE REVIEW.

2016 ◽  
Vol 9 (6) ◽  
pp. 28
Author(s):  
Mythri Halappa
Keyword(s):  
Public Health ◽  
Prescription Drugs ◽  
Health Care Professionals ◽  
Recent Trend ◽  
Public Health Practice ◽  
World Health ◽  
Public Health Importance ◽  
Self Medication ◽  
Over The Counter ◽  
Health Organization

AbstractMedications are one of the most important tools in public health practice. Since the 1980s, self‑medication is of prime public health importance as World Health Organization, in order to reduce the burden on health care professionals changed some prescription drugs to be sold over the counter. Each drug has its own advantages & disadvantages. Hence, always they have to be taken with caution. Considering this a recent trend has increased in surveying the prevalence of self medication. Hence, this review critically evaluated the studies to put a light on basic concept of self medication.Key words: Self medication, Drug abuse, Self care, Substance abuse, Antibiotic usage. 

scholarly journals Milk-Alkali Syndrome: An Unusual Cause of Acute Renal Failure

2003 ◽  
Vol 2 (2) ◽  
pp. 64-65
Author(s):  
Azhar Ahmad ◽  
◽  
Rodney Dathan ◽  
Keyword(s):  
Renal Failure ◽  
Calcium Carbonate ◽  
Metabolic Alkalosis ◽  
Case Reports ◽  
Symptomatic Treatment ◽  
Self Medication ◽  
H2 Receptor Antagonists ◽  
Over The Counter ◽  
Ulcer Disease

Milk–alkali syndrome is described as a triad of hypercalcaemia, metabolic alkalosis and renal impairment, resulting from the ingestion of calcium and absorbable alkali1. It was more common in the early part of the century when antacids were used for the symptomatic treatment of peptic ulcer disease. The use of antacids has since been overtaken by H2- receptor antagonists and proton pump inhibitors. More recently, there have been various case reports of milk-alkali syndrome due to the increasing use of calcium carbonate as part of the management of osteoporosis and chronic renal failure, and also the increasing availability of calcium carbonate ‘over the counter’. We describe a case of milk-alkali syndrome due to self-medication with calcium carbonate.

scholarly journals Behavior of Medical Students toward Over-the-Counter Drugs in Comparison to Students from Other Faculties, Riyadh, Saudi Arabia

2021 ◽  
pp. 129-135
Author(s):  
Amar Fathi Mohamed Khalifa ◽  
Yasser Nabil AlKhudairy ◽  
Adel Ahmed Algahtani ◽  
Bandar Mohammed Abduljabbar ◽  
Fahad Majed Aldawsari ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Medical Students ◽  
Cross Sectional Study ◽  
P Value ◽  
Online Questionnaire ◽  
Self Medication ◽  
Cross Sectional ◽  
Over The Counter ◽  
Otc Drugs ◽  
Professional Guidance

Background: Over-the-counter-drugs (OTC) are drugs that can be obtained by patients without a prescription from a physician. In Saudi Arabia, it has been reported that more than half of university students practiced self-medication and used OTC drugs. Methods: An institutional-based cross-sectional study, among medical and non-medical students in Riyadh. The sample size was 421, by systemic random sampling. A pre-coded pre-tested online questionnaire was used. Data was analyzed using SPSS V 23. P-value ≤ 0.05 was considered significant. Results: There was no significant relationship between what the participants were majoring in and the usage of OTC drugs (p value= 0.373). Gender also had no relation with the use of OTC (p value= 0.168). Panadol appeared as the most commonly used OTC drug 62.9% for the relief of the most commonly mentioned factor which is headache 50.12%.  Conclusion: Medical education didn’t have much of an effect on the use of OTC drugs. Moreover, professional guidance or advice was not considered most of the time for taking OTC, but the majority of respondents portrayed good behavior towards usage of OTC.

scholarly journals Evaluate use of over the counter drugs among medical students in a tertiary care teaching hospital

2019 ◽  
Vol 8 (5) ◽  
pp. 973
Author(s):  
Megha Sood ◽  
Jagminder Kaur Bajaj ◽  
Nipunjot Grewal
Keyword(s):  
Medical Students ◽  
Drug Use ◽  
Tertiary Care ◽  
Easy Access ◽  
Self Medication ◽  
Cross Sectional ◽  
Over The Counter ◽  
Care Teaching ◽  
Otc Drugs ◽  
Abdominal Symptoms

Background: In our country there is easy availability of drugs over the counter leading to their unintentional misuse and abuse. Over the counter availability of drugs does offer the benefit of easy access to medicines and allows individuals to become in charge of their own health. It is important to understand that medical education can impact the OTC drug use amongst medical students. In order to observe the pattern of OTC drug use among the first and second professional MBBS students we planned this study. The aim of the study was to evaluate use of over the counter (OTC) drugs among medical students in a tertiary care teaching hospital.Methods: Our study was a cross sectional study conducted on first and second professional MBBS students. Authors administered a self structured, prevalidated questionnaire to the students. The data obtained was tabulated, analyzed and the results calculated in percentages.Results: The use of OTC drugs is common amongst undergraduate students.  All (100%) the students who participated in the study had used OTC drugs at some point in their life. The common conditions prompting use of OTC drugs include head ache, body aches (74%), fever (72%), respiratory conditions such as: cold (60%), cough (28.5%), abdominal symptoms such as: abdominal pain (14%), gastritis (7.5%), diarrhea (6%), vomiting (5%) and allergies (10%). Very few students reported adverse drug reactions with these drugs.Conclusions: From our study we have concluded that OTC drugs are commonly used amongst medical students. So, periodic training and talks on self medication are necessary for them. Student knowledge in this aspect will help them in future counseling of their patients.

TINGKAT PENGETAHUAN PENGGUNAAN OBAT BEBAS DAN OBAT BEBAS TERBATAS UNTUK SWAMEDIKASI PADA MASYARAKAT RW 8 MOROBANGUN JOGOTIRTO BERBAH SLEMAN YOGYAKARTA

2018 ◽  
Vol 3 (2) ◽  
pp. 139
Author(s):  
Ana Hidayati ◽  
Haafizah Dania ◽  
Murtyk Dyahajeng Puspitasari
Keyword(s):  
Self Medication ◽  
Over The Counter ◽  
The People ◽  
Subject Characteristic ◽  
The World ◽  
Level Of Knowledge ◽  
The Subject

Currently, there are developed illnesses that encourage humans to do their own alternative medication. In 2002, an estimated shows that 92% of people in the world choose the alternative medication namely self medication, by using over the counter medicine including free and limited, however the level of knowledge in using this medication is still poor, then it is possible to make a mistake. Therefore, this research aims to find out the level of knowledge in using over the counter medicine including free and limited for self medication of society in RW 08, Morobangun, Jogotirto, Berbah, Sleman, Yogyakarta. This study belongs to descriptive observational to find out the subject characteristic, the level of knowledge and the description of the kind of medicine used by society of RW 08 Morobangun. The sample used in this study is the people who lived in Rw 08 Morobangun, Jogotirto, Berbah, Sleman, Yogyakarta. The data was taken from the interview with the patient by using the questionnaire. The sample collecting technique was nonrandom sampling and the method was accidental sampling with the number of the respondents were 175. The result showed that 175 respondents in RW 08 Morobangun, Jogotirto, Berbah, Sleman, Yogyakarta used self medication of over the counter medicine including free and limited only for their ailment. The level of knowledge in using over the counter medicine including free and limited for self medication of society in RW 08 Morobangun, Jogotirto, Berbah, Sleman, Yogyakarta showed that 42.9% reached the good category and 57,1% reached the sufficient category of 175 respondents. The conclusion of this study is the level of knowledge in using over the counter medicine including free and limited for self medication of society in RW 08 showed that most of the respondents achieved the sufficient category with 100 respondents (57,1%).

Differential Alterations in Host Peripheral Polymorphonuclear Leukocyte Chemiluminescence During the Course of Bacterial and Viral Infections

1980 ◽  
Vol 30 (3) ◽  
pp. 824-831
Author(s):  
James P. McCarthy ◽  
Robert S. Bodroghy ◽  
Peter B. Jahrling ◽  
Philip Z. Sobocinski
Keyword(s):  
Bacterial Infection ◽  
Oxidative Metabolism ◽  
Guinea Pigs ◽  
Viral Infections ◽  
Photon Emission ◽  
Time Intervals ◽  
Pichinde Virus ◽  
Resistance To Infection ◽  
Diagnostic And Prognostic Value

Previous studies have shown that stimulation of the oxidative metabolism in polymorphonuclear leukocytes (PMN) by in vitro phagocytosis of various microorganisms results in photon emission, termed chemiluminescence (CL). Studies were conducted to determine whether bacterial and viral infections induce enhanced basal endogenous host peripheral PMN CL in the absence of in vitro phagocytic stimulation. Nonimmune rats and guinea pigs as well as immune rats were inoculated with various doses (10 5 to 10 7 ) of live vaccine strain Francisella tularensis (per 100 g of body weight). In addition, nonimmune guinea pigs were inoculated with 40,000 plaque-forming units of Pichinde virus. Luminol-assisted endogenous PMN CL was measured at various time intervals after inoculation of microorganisms. Enhanced endogenous PMN CL was detected as early as the appearance of fever (12 h) in nonimmune animals infected with F. tularensis . Addition of sodium azide, N -ethylmaleimide, superoxide dismutase, or catalase to the CL reaction mixture containing PMN from infected animals significantly decreased the CL response. Immune rats challenged with F. tularensis exhibited resistance to infection and a decreased PMN CL compared with nonimmune rats 24 and 48 h after inoculation. However, the CL response from immune rats was significantly elevated, compared with control values. In contrast to the results obtained with the model bacterial infection, PMN isolated from guinea pigs inoculated with Pichinde virus failed to exhibit enhanced CL, compared with controls, despite significant viremia and fever. Results suggest that enhanced endogenous CL during bacterial infection occurs through mechanisms involving increased PMN oxidative metabolism and the subsequent generation of microbicidal forms of oxygen. Further, measurement of endogenous PMN CL may have diagnostic and prognostic value in infectious diseases.

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