Risk Factors for Recurrences of Pulmonary TB among Patients in Denpasar: A Case-Control Study

Author(s):  
N.L.P. Karminiasih ◽  
I.W.G. Artawan Eka Putra ◽  
Dyah Pradnyaparamita Duarsa

Background and purpose: The incidence of recurrence in patients with pulmonary tuberculosis (TB) in Denpasar in 2014 was relatively high, around 3.5% of 1082 patients. This study aimed to determine the risk factors for recurrence of pulmonary TB patients in Denpasar.Methods: The study design was a case control with 46 patients with pulmonary TB recurrence aged over 15 years as cases, and 92 patients who had recovered as control. Respondents were selected using systematic random sampling from the TB register from 2013 to 2015 in public health centers in Denpasar. Data were collected by a search of documents, observations, measurements and interviews conducted using questionnaires. Bivariate analysis was conducted (chi square test) and multivariate using logistic regression.Results: Risk factors that associated with recurrence of pulmonary TB were co-morbidity of diabetes mellitus (AOR=9.6; 95%CI: 2.17-43.08), adherence (AOR=7.6; 95%CI: 2.85-20.17), exposure to cigarette smoke during treatment (AOR=3.6; 95%CI: 1.41-9.16), home ventilation <10% (AOR=3.4; 95%CI: 1.27-9.47), house contact with pulmonary TB patients (AOR=3.1; 95%CI: 1.31-7.46) and malnutrition (AOR=2.8; 95%CI: 1.02-7.72).Conclusion: Risk factors for recurrence of pulmonary TB among patients were co-morbidity of diabetes mellitus adherence, cigarette smoke exposure during the treatment period, home ventilation <10%, house contact with pulmonary TB patients and malnutrition.

2021 ◽  
Vol 7 (1) ◽  
pp. 49-58
Author(s):  
Riska Novita ◽  
Asnawi Abdullah ◽  
Hermasnyah Hermasnyah

Background: Pulmonary TB in children is still a serious public health problem in Aceh Province, this can be seen from the increase in cases in the last three years that are suspected to be related to immunization status, nutritional status, income, knowledge, the presence of TB sufferers, occupancy density and exposure to cigarette smoke. This study aims to determine the risk factors associated with pulmonary TB incidence in children in Banda Aceh. Method: This research is an analytic observational study using a case control design. The population in this study was children suffering from pulmonary TB in Banda Aceh as many as 30 respondents. Using a ratio of 1:2 comparison, the research sample of 90 respondents consisted of 30 cases and 60 controls.  Data collection was conducted from 15 October to 15 December, conducted in the respondent's home. Data analysis using conditional multiple logistic regression test. Results: Risk factors associated with pulmonary TB in childrenare: the employment of self-employed fathers (p=0.046; OR=2.7; 95% CI: 1.01-7.50), low income (p=0.046; OR=2.7; 95% CI: 1.01-7.50), the presence of TB patients in home (p=0.001; OR=31; 95% CI: 4.11-234), cigarette smoke exposure (p=0.004; OR=4; 95% CI: 1.54-10.3), no BCG immunization (p=0.023; OR=4.6; 95% CI: 1.23-17.2), malnutrition status with the occurrence of pulmonary TB in children in Banda Aceh (p=0.002; OR=5.9; 95% CI: 1.93-18.5). The results of the multivariate analysis concluded that the tendency of pulmonary TB in children in the city of Banda Aceh to occur in the presence of TB patients at home was almost 4 times more dominant than other variables. Recommendation: To Banda Aceh Health Office in order to increase the number of pulmonary TB screening in children, especially in children with parents who suffer from pulmonary TB.


2019 ◽  
Vol 18 (1) ◽  
pp. 1
Author(s):  
Nofi Yigibalom ◽  
Sulistiyani Sulistiyani ◽  
Nurjazuli Nurjazuli

Latar Belakang: Tuberkulosis (TB) paru masih merupakan masalah kesehatan yang  menyebabkan kematian pada jutaan orang setiap tahun. Kabupaten Jayawijaya pada 2016 yang diperiksa dahak sebanyak 301 kasus dengan BTA positifnya 64 kasus bila kondisi ini terus meningkat dan berlanjut setiap tahunnya, maka Kabupaten Jayawijaya akan kehilangan manusia yang produktif. Penelitian ini bertujuan menganalisis hubungan antara kebiasaan tinggal di rumah etnis dan membuang dahak  sembarang dengan kejadian TB paru di Kabupaten Jayawijaya.Metode: Jenis penelitian ini adalah penelitian stu dyobservasional analitik dengan pendekatan case control. Subjek penelitian adalah 100 responden, yang terdiri dari 50 kasus terdiagnosis TB paru BTA positif dan 50 kontrol yang terdiagnosis BTA negatif. Pengumpulan data: wawancara, observasi langsung dan pengukuran. Analisis statistik dilakukan  menggunakan uji Chi square dengan nilai p <0,05.Hasil: Hasil Analisis univariat pencahayaan alami dalam  menunjukkan rumah rata-rata kasus 23,95 lux  dan  kontrol 24,20 lux, kelembaban rumah rata-rata 52,38 %,  kontrol 51,59%,, suhu  rumah rata-rata  kasus 27,490C,kontrol 27,260C. Analisis bivariat menunjukkan ada hubungan kebiasaan tinggal dirumah etnis honai dengan OR = 2,667 dan kebiasaan membuang dahak sembarang dengan OR = 4,750.Simpulan: Kebiasaan membuang dahak sembarang, dan kebiasaan tinggal di rumah etnis merupakan faktor risiko kejadian TB paru. Maka perlu adanya sosialisasi terkait faktor risiko kejadian TB terhadap penderita dan  masyarakat umum, serta perlu adanya perbaikan lingkungan fisik rumah dan sanitasi rumah. ABSTRACTTitle: Risk Factors For Habitual Living in Ethnic House and  Sputum Spit the  Pulmonary  TB Jayawijaya District, PapuaBackground : Tuberculosis of the lung is still a health problem that causes death to millions of people every year. Jayawijaya in 2016 examined 301 sputum smear positive cases with 64 cases if this condition continues to increase and continues each year, then the Jayawijaya Regency will lose a productive human being. This study aims to analyze the relationship between ethnic home stay habits and throw sputum arbitrarily with the incidence of pulmonary TB in Jayawijaya District.Methods : This research is an observational analytic study with case control approach. The subjects were 100 respondents, consisting of 50 cases diagnosed with positive smear pulmonary tuberculosis and 50 controls diagnosed with smear negative. Data collection: interviews, direct observation and measurement. Statistical analysis was performed using Chi square test with p value < 0,05. Results: The results of the univariate analysis showed that natural lighting in the house the average cases of 23,95 lux and control 24,20 lux, the average humidity of the house was 52,38%, control 51,59% ,, the average house temperature was 27,490C, control 27,26 0C. Bivariate analysis showed that there was an association of habitual residence of ethnic homes honai with OR = 2,667 and spiraling habit of spitting with OR = 4,750Conclusion: The habit of sputtering any sputum, and the habit of living in ethnic homes is a risk factor for pulmonary TB incidence. So the need for socialization related risk factors for TB incidence of patients and the general public, and the need for improvement of the physical environment of home and sanitation.


1997 ◽  
Vol 119 (3) ◽  
pp. 307-311 ◽  
Author(s):  
K. R. NEAL ◽  
R. C. B. SLACK

The epidemiology of notified cases of campylobacter gastroenteritis in adults in Nottingham Health District was investigated using a case-control study with a postal questionnaire to ascertain data on risk factors. Over a 14-month period 531 cases (a 73% response rate of all laboratory confirmed cases) and 512 controls replied.Conditional logistic regression analysis was used to determine independent associations with infection. These included foreign travel (odds ratio (OR) 3·4; 95% confidence intervals (CI) 2·0–5·7), diabetes mellitus (OR 4·1, CI 1·1–17), medication with omeprazole (OR 3·5, CI 1·1–12) and H2 and H2 antagonists (OR 3·7, CI 1·3–15), contact with puppies (OR11·3, CI1·2–105), eating chicken (OR 1·4, CI 1·1–1·8) and drinking milk from bottles with tops damaged by a bird (OR 3·3, CI 1·0–11). Preparing main meals (OR 0·9, CI 0·8–1·0) and drinking delivered milk (OR 0·6, CI 0·4–0·9) were associated with a reduced risk of campylobacter infection.Foreign travel was reported in 25% of cases and another 15% had significant associations with other risk factors. The majority of cases, 60%, remained unexplained, indicating the need for further evolution of sporadic cases.


2020 ◽  
Vol 8 (3) ◽  
pp. 228
Author(s):  
Denisca Vanya Almeida ◽  
Fariani Syahrul

Background: Pneumonia is one of the leading causes of death for children and is caused by pneumococcus, staphylococcus, and streptococcus bacteria. Exclusive breastfeeding and exposure to cigarette smoke are risk factors for pneumonia in children less than two years old. Purpose: The aim of this research was to analyze the relationship between exclusive breastfeeding or exposure to cigarette smoke and pneumonia in children aged less than two years at Public Health Center (PHC) of Wates, Kediri District. Methods: This research employed analytic observational research using a case–control research design. The number of research samples used was 60, consisting of 30 case respondents and 30 control respondents. The samples were taken in the PHC of Wates, Kediri District’s working area in July 2019. The determination of the samples was carried out through simple random sampling. The data were analyzed using chi-square analysis. Results: The research variables related to pneumonia in children less than two years old at PHC of Wates, Kediri District were exclusive breastfeeding with Odds Ratio (OR) = 3.50 (95% Confidence Interval (CI) = 1.20–10.19), the age of the mothers of the two-year-old infants with OR = 0.19 (95% CI = 0.04–0.78), and the education of the mothers of children less than two years old with OR = 3.14 (95% CI = 1.07–9.27). Conclusion: Exclusive breastfeeding, maternal age, and mothers’ level of education are some of the risk factors for pneumonia. The suggestion from this research is to hold socialization in the form of pneumonia prevention, education on exclusive breastfeeding for mothers who have children under two years of age, and the dangers of smoking for children's health.


Author(s):  
Made Krisna Adi Jaya ◽  
Dewa Ayu Swastini ◽  
Baiq Leny Nopitasari ◽  
Putu Rika Veryanti

Background: Diabetic Peripheral Neuropathy (DPN) is a microvascular complication that commonly occurs in people with diabetes mellitus. Geriatrics with type 2 diabetes mellitus is one of the populations most vulnerable to this complication. An epidemiological study states that geriatrics has a 32% greater risk of developing this complication compared to other age groups. There have not been many studies conducted to evaluate the risk factors that influence this DPN complication, so it needs to be done an individual evaluation for the elderly population. Objective: This study aims to explore the risk factors that influence the incidence of DPN in elderly patients with type 2 diabetes mellitus. Methods: A case-control study design was carried out on 70 geriatrics with type 2 diabetes mellitus. The outcome determined was the incidence of DPN to track the cause of DPN exposure retrospectively. Influential risk factors are determined by the Odds Ratio (OR) with a 95% confidence interval (CI). All statistical analyzes were two-tailed, and p-values <0.05 were considered as statistically significant. Results: Seven factors influence the incidence of DPN in the elderly consisting of smoking history (OR=13.1), uncontrolled lipid profile (OR=5.1), non-neuroprotector users (OR=5.6), uncontrolled blood glucose (OR=42.7), history of heart disease (OR=9.0), uncontrolled blood pressure (OR=4.3), and BMI above normal (OR=5.1). Conclusion: Strong recommendation for medical personnel to focus attention on seven significant risk factors affected complications of DPN to reduce its progression or prevent upcoming complications.


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