scholarly journals Therapeutic Potential of Saffron Crocus (Crocus sativus L.)

2016 ◽  
Vol 4 (12) ◽  
pp. 1240 ◽  
Author(s):  
Zeliha Selamoglu ◽  
Senay Ozgen
Keyword(s):  
Medicinal Plants ◽  
Scarlet Fever ◽  
Therapeutic Potential ◽  
Heart Diseases ◽  
Folk Medicine ◽  
Crocus Sativus ◽  
Folk Remedy ◽  
Herbal Plants ◽  
Crocus Sativus L

Herbal plants are using for folk medicine since immemorial times. Hippocrates who is the father of medicine, refer to 400 medicinal plants and advised ‘‘let food be your medicine and let medicine be your food’’. Most of plants are using today for medicine. It is still acceptable today that prevention is more important than treatment. Saffron was utilized in folk remedy against scarlet fever, smallpox, colds, asthma, eye and heart diseases, tumours, and cancer.

scholarly journals Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential

Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4226
Author(s):  
Nikolaos Pitsikas ◽  
Konstantinos Dimas
Keyword(s):  
Natural Products ◽  
Secondary Metabolites ◽  
Organic Compounds ◽  
Therapeutic Potential ◽  
Crocus Sativus ◽  
Natural Sources ◽  
Crocus Sativus L

Natural products or organic compounds isolated from natural sources as primary or secondary metabolites have inspired numerous drugs [...]

scholarly journals Pharmacological properties and therapeutic potential of saffron ( Crocus sativus L.) in osteosarcoma

2019 ◽  
Vol 72 (1) ◽  
pp. 56-67 ◽  
Author(s):  
Bilal Ege ◽  
Onder Yumrutas ◽  
Miray Ege ◽  
Mustafa Pehlivan ◽  
Ibrahim Bozgeyik
Keyword(s):  
Therapeutic Potential ◽  
Crocus Sativus ◽  
Pharmacological Properties ◽  
Crocus Sativus L

scholarly journals An Overview of Some Plant Based Products With Hepatoprotective Activity

2021 ◽  
Vol 30 (2) ◽  
pp. 1-15
Author(s):  
Sonali Dnyaneshwar Labhade ◽  
Swapnil Sharma ◽  
Sarvesh Paliwal ◽  
Shivani Desai
Keyword(s):  
Medicinal Plants ◽  
Therapeutic Potential ◽  
Folk Medicine ◽  
Herbal Medicines ◽  
Repeated Administration ◽  
Hepatoprotective Activity ◽  
Hepatoprotective Effect ◽  
Quality Trait ◽  
Liver Disorders ◽  
Current Review

In folk medicine there are various medicinal amalgamation possessing hepatoprotective activity. This activity is of significance because several toxins cause liver injury. Hence, many pharmaceutical companies are targeting herbal medicines for the treatment of liver abnormalities and towards evolving a safe and effective formulation with desired route of administration. In current review we have focused on the studies showing hepatoprotective effect using marine compounds and plant derived compounds. Liver disorder, a global health problem, usually include acute or chronic hepatitis, heptoses, and cirrhosis. It may be due to toxic chemicals and certain antibiotics. Uncontrolled consumption of alcohol also affects liver in an unhealthy way. To cure liver disorders several formulations of medicinal plants are being used. It is observed that hepatoprotective effect of plant is mostly due to flavonoids, alkaloids, terpenoids, steroids, and glycoside. A single drug cannot be useful for all the types of liver disorders. Several plant extracts for liver illness results from poisonous chemicals, viruses, extra alcohol consumption, and repeated administration of medication. By using standards of protection and efficacy, manufacture of plant products need to be ruled out. Current review provides an understanding of ethnopharmocology, toxicology of several medicinal plants manifesting hepatoprotective potential. Despite of varied database analysis new discoveries and their probabilities, evidences on viral hepatitis treatment or liver cirrhosis is inadequate.  Further information about phytotherapy, toxicology, quality control studies shall be endorsed. Further in depth studies are required to discover quality trait like SAR, MOA, safety and toxicity and therapeutic potential of phytoconstituents in clinical settings.

scholarly journals Traditional and Modern Uses of Saffron (Crocus Sativus)

Cosmetics ◽  
2019 ◽  
Vol 6 (4) ◽  
pp. 63 ◽  
Author(s):  
Mzabri ◽  
Addi ◽  
Berrichi
Keyword(s):  
Medicinal Plants ◽  
Folk Medicine ◽  
Global Market ◽  
Crocus Sativus ◽  
Pharmacological Activities ◽  
Aromatic And Medicinal Plants ◽  
The World ◽  
Main Components

The Aromatic and Medicinal Plants sector has undergone a remarkable evolution, especially during the last decade. The global market is moving more and more towards products of natural origin. Indeed, of the 4200-existing plant in Morocco, 800 are listed as aromatic and medicinal plants. Among these plants, saffron is a source of income for many areas of Morocco. Saffron, the dried stigma of the Crocus sativus flower, is considered among the main terroir products of Morocco. Saffron has accompanied all civilizations, whether for its culinary role, for its quality of dye or its ancestral virtues rooted in folk medicine. This review highlights the main components of saffron, and the pharmacological activities that result from it and make this product a serious therapeutic hope. Then, a classification of uses of saffron was carried out according to its uses, traditional, pharmaceutical, cosmetic and perfumery without forgetting its use a spice incorporated in many dishes around the world.

scholarly journals Medicinal Plants in the Treatment of Depression: Evidence from Preclinical Studies

Planta Medica ◽  
2021 ◽  
Author(s):  
Inés Moragrega ◽  
José Luis Ríos
Keyword(s):  
Medicinal Plants ◽  
Therapeutic Potential ◽  
Folk Medicine ◽  
Depression And Anxiety ◽  
Neuroprotective Effects ◽  
Treatment Of Depression ◽  
Natural Remedies ◽  
Relevant Group ◽  
Preclinical And Clinical Studies ◽  
Year 2000

AbstractMedicinal plants and their extracts are natural remedies with enormous potential for treating various diseases, including depression and anxiety. In the case of depression, hundreds of plants have traditionally been used in folk medicine for generations. Different plant extracts and natural products have been analyzed as potential antidepressant agents with validated models to test for antidepressant-like effects in animals, although other complementary studies have also been employed. Most of these studies focus on the possible mediators implicated in these potential effects, with dopamine, serotonin, and noradrenaline being the principal neurotransmitters implicated, both through interference with receptors and with their metabolism by monoamino oxidases, as well as through neuro-endocrine and neuroprotective effects. There are approximately 650 reports of antidepressant-like medicinal plants in PubMed; 155 of them have been compiled in this review, with a relevant group yielding positive results. Saffron and turmeric are the most relevant species studied in both preclinical and clinical studies; St. Johnʼs wort or kava have also been tested extensively. To the best of our knowledge, no review to date has provided a comprehensive understanding of the biomolecular mechanisms of action of these herbs or of whether their potential effects could have real benefits. The purpose of this narrative review is to provide an update regarding medicinal plants from the year 2000 to the present to examine the therapeutic potential of these antidepressant-like plants in order to contribute to the development of new therapeutic methods to alleviate the tremendous burden that depression causes worldwide.

scholarly journals Astragalus (Astragalus membranaceus Bunge): botanical, geographical, and historical aspects to pharmaceutical components and beneficial role

2021 ◽  
Author(s):  
Alessandra Durazzo ◽  
Amirhossein Nazhand ◽  
Massimo Lucarini ◽  
Amelia M. Silva ◽  
Selma B. Souto ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Therapeutic Potential ◽  
Folk Medicine ◽  
Astragalus Membranaceus ◽  
Special Focus ◽  
Comprehensive Overview ◽  
Historical Aspects ◽  
Therapeutic Properties

AbstractMedicinal plants always are part of folk medicine and are nowadays receiving worldwide attention for prophylaxis, management, and treatment of several diseases, as an alternative to chemical drugs. The current work provided a comprehensive overview and analysis of the Astragalus and health relationship in literature. The analysis of their therapeutic potential is thus instrumental to understand their bioactivity. Among these, the flowering medicinal plant Astragalus membranaceus has raised interest due to several beneficial health effects. This perspective review discussed the botanical, geographical, historical, and the therapeutic properties of A. membranaceus, with a special focus on its health improving effects and medicinal applications both in vitro and in vivo. Graphic abstract

scholarly journals O uso de plantas medicinais é efetivo para o controle de sintomas depressivos em adultos?: Uma revisão integrativa

2022 ◽  
Vol 11 (1) ◽  
pp. e35611124520
Author(s):  
Laiane Silva dos Santos ◽  
Lucivania Cordeiro Silva ◽  
Martone Moreira Conceição ◽  
Rosana Souza do Nascimento ◽  
Gisele Lopes de Oliveira ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Depressive Disorder ◽  
Adult Population ◽  
Crocus Sativus ◽  
Herbal Plants

Este estudo buscou contribuir para a identificação e síntese das evidências de ensaios controlados randomizados sobre os efeitos do uso das plantas medicinais no controle dos sintomas depressivos em adultos. Trata-se de uma revisão integrativa, com busca realizada em bases de dados, utilizando os seguintes termos: (medicinal plants OR herbal plants), (depressive disorder OR depression), and (adults OR adult population). Foram incluídos: ensaios controlados randomizados; publicados em artigos originais disponíveis na íntegra; em língua inglesa ou portuguesa, e realizados com adultos de 18 a 59 anos. Foram excluídos os artigos duplicados e que não atenderam aos critérios de inclusão. A busca resultou em um total de 354 estudos, sendo 9 estudos incluídos para análise. A Crocus sativus (açafrão) foi a planta medicinal mais utilizada, com administração por meio de cápsulas em um período entre 4 e 12 semanas. O uso das plantas medicinais mostrou efeitos positivos para redução da intensidade dos sintomas de depressão, melhora do desempenho da memória e do humor, e melhora na qualidade do sono. No entanto, este resultado deve ser interpretado com moderação, em razão do número de estudos e da qualidade metodológica.

scholarly journals Therapeutic Potential of Saffron (Crocus sativus L.) in Ischemia Stroke

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Shakiba Azami ◽  
Zahra Shahriari ◽  
Samira Asgharzade ◽  
Tahereh Farkhondeh ◽  
Mahmood Sadeghi ◽  
...  
Keyword(s):  
Therapeutic Potential ◽  
Crocus Sativus ◽  
Pharmacological Effects ◽  
Oxidative Stress Markers ◽  
Neuroprotective Effects ◽  
Beneficial Effects ◽  
Stress Markers ◽  
Ancient Times ◽  
And Oxidative Stress ◽  
Crocus Sativus L

Stroke is the second leading cause of death and a main cause of disability worldwide. The majority (approximately 80%) of strokes are ischemic. Saffron (Crocus sativus L.) has been considered for medicinal purposes since ancient times. Pharmacological effects of saffron are attributed to the presence of crocin, crocetin, picrocrocin, and safranal. In the present review, we summarized the reported neuroprotective effects of saffron and its active constituents against cerebral ischemia stroke. Saffron and its components exert its beneficial effects as an antioxidant, anti-inflammatory, and antiapoptotic agent though inhibition of biochemical, inflammatory, and oxidative stress markers. Taken together, this review indicates that saffron and its ingredients could be a potent candidate in the process of new drug production for the treatment of ischemia stroke.

scholarly journals Neuroscience and herbal plants: A review on the most important herbal plants effective on chronic pain

2019 ◽  
Vol 6 (4) ◽  
pp. 383-388
Author(s):  
Saber Abbaszadeh ◽  
Parisa Arvin ◽  
Mojtaba Khaksarian
Keyword(s):  
Chronic Pain ◽  
Medicinal Plants ◽  
Interpersonal Relationships ◽  
Tissue Injury ◽  
Solanum Melongena ◽  
Psychomotor Retardation ◽  
Crocus Sativus ◽  
Rosa Damascena ◽  
Hyoscyamus Niger ◽  
Herbal Plants

Chronic pain can be periodic, persistent, or even a combination of both. Unlike acute pain, chronic pain is not usually useful, reduces the quality of life and functional abilities and also weakens mental health, interpersonal relationships, and financial status, leading to changes in appetite, sleep disorders, psychomotor retardation, tiredness and depression. Human being has always faced various kinds of pain during life and sought to relieve his pain. Pain is a sign of a disease that acts as a warning mechanism and informs of a tissue injury. In this regard, the analgesic effects of many medicinal plants have also been studied. Therefore, in this review study, indigenous medicinal plants with anti-chronic pain effects were reported. Information to conduct this review was obtained using the keywords chronic pain, herbal drug, Iran, medicinal plants, extracts and essential oils to retrieve articles indexed in databases such as Scopus, SID, Magiran, Google Scholar and other Persian databases. The related articles were reviewed for plants serving as chronic pain killers. After reviewing the literature, it was found that Solanum melongena, Hyoscyamus niger, Phoenix dactylifera, Cinnamomum zeylanicum, Artemisia sieberi, Crocus sativus, Carum copticum, Euphorbia helioscopia, Hypericum perforatum, Cucurbita maxima, Passiflora caerulea, Rosa damascena, Tanacetum parthenium, Allium jesdianum and Pistacia atlantica among indigenous medicinal plants with analgesic effect.

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