scholarly journals An Overview of Some Plant Based Products With Hepatoprotective Activity

2021 ◽  
Vol 30 (2) ◽  
pp. 1-15
Author(s):  
Sonali Dnyaneshwar Labhade ◽  
Swapnil Sharma ◽  
Sarvesh Paliwal ◽  
Shivani Desai
Keyword(s):  
Medicinal Plants ◽  
Therapeutic Potential ◽  
Folk Medicine ◽  
Herbal Medicines ◽  
Repeated Administration ◽  
Hepatoprotective Activity ◽  
Hepatoprotective Effect ◽  
Quality Trait ◽  
Liver Disorders ◽  
Current Review

In folk medicine there are various medicinal amalgamation possessing hepatoprotective activity. This activity is of significance because several toxins cause liver injury. Hence, many pharmaceutical companies are targeting herbal medicines for the treatment of liver abnormalities and towards evolving a safe and effective formulation with desired route of administration. In current review we have focused on the studies showing hepatoprotective effect using marine compounds and plant derived compounds. Liver disorder, a global health problem, usually include acute or chronic hepatitis, heptoses, and cirrhosis. It may be due to toxic chemicals and certain antibiotics. Uncontrolled consumption of alcohol also affects liver in an unhealthy way. To cure liver disorders several formulations of medicinal plants are being used. It is observed that hepatoprotective effect of plant is mostly due to flavonoids, alkaloids, terpenoids, steroids, and glycoside. A single drug cannot be useful for all the types of liver disorders. Several plant extracts for liver illness results from poisonous chemicals, viruses, extra alcohol consumption, and repeated administration of medication. By using standards of protection and efficacy, manufacture of plant products need to be ruled out. Current review provides an understanding of ethnopharmocology, toxicology of several medicinal plants manifesting hepatoprotective potential. Despite of varied database analysis new discoveries and their probabilities, evidences on viral hepatitis treatment or liver cirrhosis is inadequate.  Further information about phytotherapy, toxicology, quality control studies shall be endorsed. Further in depth studies are required to discover quality trait like SAR, MOA, safety and toxicity and therapeutic potential of phytoconstituents in clinical settings.

scholarly journals The traditional medicine and phytoconstituents from natural products for liver disease: A review

2019 ◽  
Vol 9 (2) ◽  
pp. 484-488
Author(s):  
Tabasum Ali ◽  
Zahida Shah ◽  
Rabiah Bashir ◽  
G.N. Bader
Keyword(s):  
Natural Products ◽  
Liver Disease ◽  
Medicinal Plants ◽  
Traditional Medicine ◽  
Herbal Medicines ◽  
Hepatoprotective Activity ◽  
Liver Disorders ◽  
Herbal Preparations ◽  
Scientific Support ◽  
Pharmacologically Active

To combat a variety of liver ailments medicinal plants may serve as a vital source because of presence of pharmacologically active phytoconstituents. It is very interesting to note that there is no drug available in the modem system of medicine for treating hepatic disorders; only certain herbal preparations are available to treat this quite vulnerable disease. A large number of plants with hepatoprotective activity are present but only handful of herbs have such scientific support. Herbal medicines have been used to alleviate liver disorders for many centuries and have currently become a favorable therapy for pathological liver disease. Keywords: Liver disease, Herb, Hepatoprotective activity

scholarly journals Therapeutic Potential of Saffron Crocus (Crocus sativus L.)

2016 ◽  
Vol 4 (12) ◽  
pp. 1240 ◽  
Author(s):  
Zeliha Selamoglu ◽  
Senay Ozgen
Keyword(s):  
Medicinal Plants ◽  
Scarlet Fever ◽  
Therapeutic Potential ◽  
Heart Diseases ◽  
Folk Medicine ◽  
Crocus Sativus ◽  
Folk Remedy ◽  
Herbal Plants ◽  
Crocus Sativus L

Herbal plants are using for folk medicine since immemorial times. Hippocrates who is the father of medicine, refer to 400 medicinal plants and advised ‘‘let food be your medicine and let medicine be your food’’. Most of plants are using today for medicine. It is still acceptable today that prevention is more important than treatment. Saffron was utilized in folk remedy against scarlet fever, smallpox, colds, asthma, eye and heart diseases, tumours, and cancer.

scholarly journals Hepatoprotective Activity of Some Medicinal Plants in Sudan

2019 ◽  
Vol 2019 ◽  
pp. 1-16 ◽  
Author(s):  
Sumaia A. Ali ◽  
Noha H. Sharief ◽  
Yahya S. Mohamed
Keyword(s):  
Animal Models ◽  
Medicinal Plants ◽  
Rural Areas ◽  
Scientific Evidence ◽  
Hepatoprotective Activity ◽  
Active Principle ◽  
Published Data ◽  
Liver Disorders ◽  
Herbal Plants ◽  
Liver Markers

Background. Liver disorders are common in Sudan and elsewhere. These are traditionally treated by medicinal plants especially in rural areas where they are widely available. Methods. This review was based on scientific research in hepatoprotective plants performed in Sudan for the period between 2001 and 2016 AD. Data collection was done through scientific evidence of local and international published data, theses, and publications from some libraries in Sudanese universities. Internet was also used to collect published data in different international scientific journals. Results. In this study, 21 plants from different families were reviewed for the hepatoprotective activity in Sudan. These plants are widely used in traditional medicine for their availability and cheap prices. All of these plants have been scientifically investigated through experimental animal models which confirmed their hepatoprotective activities. This was evaluated by measuring several parameters including liver markers (AST, ALT, ALP, total protein, albumin, and bilirubin) and histopathological investigation. Nineteen (90.5%) of the herbal plants were found to possess significant hepatoprotective activity in animal models. Two (9.5%) of the plants were devoid of this activity. The action of these plants is largely attributed to their phytoconstituents such as flavonoids, antioxidant, and anti-inflammatory effects. Conclusion. Sudanese herbs may offer novel alternatives to treat liver disorders. Yet determination of the active principle responsible for hepatoprotection needs to be investigated. Further studies on these plants are necessary to establish the efficacy, safety, and exact mechanism of action as a moral alternative in the treatment of liver disorders.

scholarly journals Medicinal plants with hepatoprotective activity in Iranian folk medicine

2015 ◽  
Vol 5 (2) ◽  
pp. 146-157 ◽  
Author(s):  
Majid Asadi-Samani ◽  
Najme Kafash-Farkhad ◽  
Nafiseh Azimi ◽  
Ali Fasihi ◽  
Ebrahim Alinia-Ahandani ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Folk Medicine ◽  
Hepatoprotective Activity

scholarly journals Medicinal Plants in the Treatment of Depression: Evidence from Preclinical Studies

Planta Medica ◽  
2021 ◽  
Author(s):  
Inés Moragrega ◽  
José Luis Ríos
Keyword(s):  
Medicinal Plants ◽  
Therapeutic Potential ◽  
Folk Medicine ◽  
Depression And Anxiety ◽  
Neuroprotective Effects ◽  
Treatment Of Depression ◽  
Natural Remedies ◽  
Relevant Group ◽  
Preclinical And Clinical Studies ◽  
Year 2000

AbstractMedicinal plants and their extracts are natural remedies with enormous potential for treating various diseases, including depression and anxiety. In the case of depression, hundreds of plants have traditionally been used in folk medicine for generations. Different plant extracts and natural products have been analyzed as potential antidepressant agents with validated models to test for antidepressant-like effects in animals, although other complementary studies have also been employed. Most of these studies focus on the possible mediators implicated in these potential effects, with dopamine, serotonin, and noradrenaline being the principal neurotransmitters implicated, both through interference with receptors and with their metabolism by monoamino oxidases, as well as through neuro-endocrine and neuroprotective effects. There are approximately 650 reports of antidepressant-like medicinal plants in PubMed; 155 of them have been compiled in this review, with a relevant group yielding positive results. Saffron and turmeric are the most relevant species studied in both preclinical and clinical studies; St. Johnʼs wort or kava have also been tested extensively. To the best of our knowledge, no review to date has provided a comprehensive understanding of the biomolecular mechanisms of action of these herbs or of whether their potential effects could have real benefits. The purpose of this narrative review is to provide an update regarding medicinal plants from the year 2000 to the present to examine the therapeutic potential of these antidepressant-like plants in order to contribute to the development of new therapeutic methods to alleviate the tremendous burden that depression causes worldwide.

scholarly journals Future perspectives of Therapeutic Claims of an Ethnopharmacological Drug Ipomoea carnea Jacq. - A Critical Review

2021 ◽  
Vol 12 (2) ◽  
pp. 177-184
Author(s):  
Nilima Wadnerwar ◽  
Meena Deogade
Keyword(s):  
Therapeutic Potential ◽  
Folk Medicine ◽  
Herbal Medicines ◽  
Human Beings ◽  
Efficacy And Safety ◽  
Future Perspectives ◽  
Ipomoea Carnea ◽  
Therapeutic Uses ◽  
Pharmacological Studies ◽  
Toxic Potential

Ipomoea carnea Jacq is an ethnopharmacological drug used for various indications by healers. As the herbal medicines are becoming endangered, ethanopharmacological drug can be used efficiently as they are available abundantly. The aim of this article is to highlight the therapeutic uses of Ipomoea carnea and to stress the use of ethanopharmacological drug vividly in the treatment. Materials and Methods: The data was located from books including ethnopharmacological drugs, Indian flora, traditional medicine and articles in various journals out of which only the data related to Identification of the species, pharmacological researches, therapeutic and other uses of Ipomoea carnea Jacq was selected. The data was segregated, edited, consolidated and reviewed critically to explore the therapeutic potential of the drug. Result: Phytochemical, invivo and invitro pharmacological studies indicate the therapeutic potential of Ipomoea carnea but there is scarcity of clinical evidences to prove their efficacy and safety in human beings. Discussion and Conclusion: Ipomoea carnea has significant pharmacological and therapeutical value. Though it is used as folk medicine, no clinical study has been conducted to evaluate the efficacy or to evaluate the toxic potential of Ipomoea carnea leaves, seeds or any other part.

scholarly journals Astragalus (Astragalus membranaceus Bunge): botanical, geographical, and historical aspects to pharmaceutical components and beneficial role

2021 ◽  
Author(s):  
Alessandra Durazzo ◽  
Amirhossein Nazhand ◽  
Massimo Lucarini ◽  
Amelia M. Silva ◽  
Selma B. Souto ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Therapeutic Potential ◽  
Folk Medicine ◽  
Astragalus Membranaceus ◽  
Special Focus ◽  
Comprehensive Overview ◽  
Historical Aspects ◽  
Therapeutic Properties

AbstractMedicinal plants always are part of folk medicine and are nowadays receiving worldwide attention for prophylaxis, management, and treatment of several diseases, as an alternative to chemical drugs. The current work provided a comprehensive overview and analysis of the Astragalus and health relationship in literature. The analysis of their therapeutic potential is thus instrumental to understand their bioactivity. Among these, the flowering medicinal plant Astragalus membranaceus has raised interest due to several beneficial health effects. This perspective review discussed the botanical, geographical, historical, and the therapeutic properties of A. membranaceus, with a special focus on its health improving effects and medicinal applications both in vitro and in vivo. Graphic abstract

scholarly journals A Pharmacological Review: Leptadenia reticulata (Wight & Arn.); Jivanti: the Real Life Giving Plant

Folia Medica ◽  
2017 ◽  
Vol 59 (4) ◽  
pp. 405-412
Author(s):  
Jayesh M. Dhalani ◽  
Pankaj B. Nariya
Keyword(s):  
Therapeutic Potential ◽  
Folk Medicine ◽  
Real Life ◽  
Hepatoprotective Activity ◽  
Nano Particles ◽  
Present Review ◽  
Antidiabetic Activity ◽  
Pharmacological Studies ◽  
Tone Of Voice ◽  
Herbal Formulations

AbstractThe present review reveals a comprehensive description of various pharmacological studies carried out on Leptadenia reticulata, a source of several active compounds, i.e. Leptadenia reticulata plant belonging to family Asclepiadaceae, it is also known as ‘Jivanti’, used for the treatment of various ailments in human civilization as well as used in folk medicine as a remedy in various reported herbal formulations. The plant has been found to exhibit diverse pharmacological activities like antibacterial activity, anticancer activity, lactogenic eff ect, antioxidant activity, anti-implantation activity, anti-asthmatic activity, modulating eff ect, activity of silver nano particles, hepatoprotective activity, antifungal activity, antidiabetic activity and anti-infl ammatory activity. Traditionally, the plant promotes fi tness and vigor, the tone of voice, cures eye diseases, fever, and night blindness, cough, maintain pregnancy and gangrene. In this review, we give the recent scientifi c update on this plant with therapeutic potential and discuss the methods of carrying out studies. The present review draws the attention of researchers towards the potential therapeutic activity of Leptadenia reticulata for their active constitute.

scholarly journals A LITERARY REVIEW ON KALMEGH AND BHUMYAMLAKI AS HEPATOPROTECTIVE MEDICINAL PLANTS

2021 ◽  
Vol 9 (4) ◽  
pp. 810-817
Author(s):  
Nabaruna Bose ◽  
Gupta O.P.
Keyword(s):  
Medicinal Plants ◽  
Liver Diseases ◽  
Lifestyle Modification ◽  
Holistic Approach ◽  
Hepatoprotective Activity ◽  
The Body ◽  
New Drugs ◽  
Liver Disorders ◽  
Synthetic Drugs ◽  
Medicinal Properties

India is rich in flora of various kinds having several medicinal properties which are already known to us while some are yet to be discovered and used for the betterment of the human mankind. The practice of using indige- nous plants for the treatment of various health ailments has been an age-old practice. With the advancement in technology and lifestyle modification people are suffering from liver diseases and it is a worldwide problem now. Liver is a vital organ which plays a major role in the metabolism and excretion of xenobiotics from the body. The currently available synthetic drugs cause damage to the liver so it is imperative to find new drugs with least side effects. In Ayurveda, various medicinal plants are mentioned which are efficient in protecting liver from various harmful agents or toxins causing diseases. Kalmegha and Bhumyamlaki mentioned in various Ayurvedic texts has hepatoprotective activity. Ayurveda has a holistic approach. It believes in organic way of treatment by eliminating the toxins and balancing the Tridosha. The review has been done based on both Ayurvedic text and modern exper- imental studies. In this regard, their morphology, phytochemistry, Ayurvedic pharmacology, effects and trial stud- ies and dosages are focused on. The introduced medicinal plants can be used for production of new drugs via an- tioxidant related properties, hepatoprotective activities for the prevention and treatment of liver disorders. Keywords: Ayurveda, Kalmegha, Bhumyamlaki, Hepatoprotective.

scholarly journals REVIEW ON MEDICINAL PLANTS UNVEILING HEPATOPROTECTIVE ACTIVITY

2021 ◽  
Vol 12 (6) ◽  
pp. 75-86
Author(s):  
Swarnalatha G ◽  
Poojitha M
Keyword(s):  
Medicinal Plants ◽  
Human Body ◽  
Hepatoprotective Activity ◽  
The Other ◽  
Therapeutic Drugs ◽  
Current Review ◽  
Treat All ◽  
Main Center

Medicinal plants have remained as a godsend for the current scientific advancements in terms of providing dealing with diseases. The current review provides the data regarding the medicinal plants which have been reported for hepatoprotective activity and which are to be reported for treating many disorders of humankind. The review covers the recent and updated data of medicinal plants to treat all kinds of hepatic disorders which are studied by inducing different methods. As the main metabolic center of human body liver plays a major role in disintegrating the drugs and also considered as the main center which can be affected easily due to toxicity and with the other disorders that can be elicited due to excess use of therapeutic drugs or due to mis use of drugs.

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