scholarly journals Improving Vaccine Safety by Using an Algorithmic Model as a Replacement for a Physical Thermal Buffer

2018 ◽  
Vol 9 (1) ◽  
pp. 10
Author(s):  
Michael Richard Rusnack
Keyword(s):  
Air Temperature ◽  
Vaccine Safety ◽  
Storage Conditions ◽  
False Alarms ◽  
Mathematical Algorithm ◽  
Temperature Probe ◽  
Actual Experience ◽  
Buffer Medium ◽  
Conventional Practice ◽  
Algorithmic Model

Conventional practice in vaccine storage is to insert a temperature probe into a bottle of glycol, or another equivalent thermal buffer medium, to simulate the temperature experience of the stored vaccine, rather than just the air temperature.  Such a thermal buffer is intended to reduce false alarms so that the drug manager will know with higher confidence that a temperature alert is an event requiring action. While necessary and appropriate to correctly monitor the storage conditions, it is a practice that is messy, inconvenient, and costly, and can result in reports that diverge from the actual experience of the stored inventory.  This paper explores the use of a mathematical algorithm to reproduce the behavior of a physical thermal buffer medium. The paper describes the algorithm and reports the degree to which it accurately simulates the experience of a 20-ml glycol container. The algorithm is shown to be highly predictive of the temperatures measured inside a container containing glycol.

scholarly journals Naturally triggered persistent deep slab avalanches in western Canada Part I: avalanche characteristics and weather trends from weather stations

2016 ◽  
Vol 62 (232) ◽  
pp. 243-255 ◽  
Author(s):  
MICHAEL CONLAN ◽  
BRUCE JAMIESON
Keyword(s):  
Air Temperature ◽  
Classification Tree ◽  
Decision Aids ◽  
Companion Paper ◽  
Wind Loading ◽  
False Alarms ◽  
Western Canada ◽  
Weather Model ◽  
Weather Stations ◽  
Median Maximum

ABSTRACTA database of difficult-to-forecast natural persistent deep slab avalanches was analyzed to determine thresholds for parameters that contribute to their release in western Canada. The database included avalanche observations and weather station data. The avalanches were grouped based on their primary cause-of-release, either precipitation loading, wind loading, solar warming or air temperature warming using a multivariate classification tree, which first split using a solar warming parameter. The precipitation group had a median 24 h snowfall of 15 cm and 3 d snowfall of 38 cm at weather stations, mostly at or below treeline. These amounts were likely closer between 20–30 and 50–80 cm at alpine start zones. The wind loading group experienced the most wind-transported snow potential. The solar warming group had predicted solar warming of 5.2°C, 10 cm into the snowpack, on the days of release. The air temperature warming group experienced the highest median maximum air temperature (5°C) on the days of release. These thresholds may be useful to forecast the likelihood of similar avalanches with experienced-based forecasting or with decision aids, although many false alarms are possible. A companion paper, Part II, relates weather model data to avalanche occurrences.

scholarly journals Stickiness and agglomeration of blackberry and raspberry spray dried juices using agave fructans and maltodextrin as carrier agents

2020 ◽  
Vol 38 (No. 4) ◽  
pp. 229-236
Author(s):  
Vania S. Farías-Cervantes ◽  
Yolanda Salinas-Moreno ◽  
Alejandra Chávez-Rodríguez ◽  
Guadalupe Luna-Solano ◽  
Hiram Medrano-Roldan ◽  
...  
Keyword(s):  
Spray Drying ◽  
Air Temperature ◽  
Storage Conditions ◽  
Spray Dryer ◽  
Stability Diagrams ◽  
Particle Stability ◽  
The Stability ◽  
Spray Dried

The present study shows the effect of agave fructans as a carrier agent compared with maltodextrin to evaluate the particle stability of blackberry and raspberry juices. A pilot spray dryer was used with feed flow of 20 mL h–1 and atomization rate of 28 000 rpm. The inlet air temperature of 180 °C and outlet air temperature of 80 °C were used as parameter constants. Only the parameters of the carrier agent concentration of 5, 7.5 to 10% (w/v) were changed. The concentration of 10% agave fructans was high enough to recover the higher yields of 89% only for blackberry, for raspberry the concentration of 7.5% agave fructans was sufficient to recover the yield of 67%. The stability diagrams show the conditions of the particles that should not be exceeded when leaving spray drying, as well as the storage conditions that must be followed to avoid agglomeration.

scholarly journals ARMAZENAMENTO DOS PRODUTOS PARA SAÚDE EM CENTROS DE ESTERILIZAÇÃO DE HOSPITAIS

2018 ◽  
Vol 8 (4) ◽  
Author(s):  
Ivone Coutinho Mussel ◽  
Adriana Oliveira De Paula ◽  
Adriana Cristina De Oliveira
Keyword(s):  
Relative Humidity ◽  
Data Collection ◽  
Medical Device ◽  
Air Temperature ◽  
Storage Conditions ◽  
Descriptive Statistics ◽  
Expiry Date ◽  
Health Products ◽  
Belo Horizonte ◽  
Structured Questionnaire

Objetivo: descrever condições de armazenamento dos produtos estéreis em Centros de Material Esterilizado de hospitais de grande porte. Metodologia: conduziu-se um estudo de abordagem quantitativa, realizada em dez hospitais de Belo Horizonte, entre maio e setembro de 2013. Para a coleta de dados utilizou-se um questionário estruturado e as análises por meio da estatística descritiva. Resultados: o acondicionamento do produto para saúde é feito em armários fechados (60%), com revestimento lavável (100%), com controle de umidade relativa do ar e temperatura. O controle da data de validade dos produtos foi referido em todos os centros de material e esterilização e o transporte em carros exclusivos em 80%; 30% não possuíam área física exclusiva para produtos estéreis, armazenando-os junto a materiais não estéreis. Conclusão: Observou-se a necessidade uma maior atenção ao armazenamento do produto para saúde e ao cumprimento da legislação vigente.Descritores: Armazenamento de Substâncias, Produtos e Materiais, Esterilização, Enfermagem, Segurança do Paciente.STORAGE OF HEALTH PRODUCTS IN HOSPITAL STERILIZATION CENTERSObjective: describe storage conditions for sterile products Sterilized Material Centers of large hospitals. Methodology: We conducted a study of quantitative approach, between May and September 2013 in ten hospitals. For data collection was used a structured questionnaire and analyzes using descriptive statistics. Results: the packaging of the medical device is given in closed cabinets (60%), with washable lining (100%), with control of relative humidity and air temperature. The control of the expiry date of the products mentioned in all material and sterilization centers and transport in exclusive cars by 80%; 30% did not have exclusive physical area for sterile products, storing them together with non-sterile materials. Conclusion: There is a need for greater attention to the storage of the product for health and compliance with current legislation.Descriptors: Storage of Substances, Products and Materials, Sterilization, Nursing, Patient Safety.EL ALMACENAMIENTO DE PRODUCTOS SANITARIOS EN LOS CENTROS HOSPITALARIOS DE ESTERILIZACIÓNObjetivo: describir las condiciones de almacenamiento de los productos estériles esterilizadas los centros de material de grandes hospitales. Métodos: Se realizó un estudio de enfoque cuantitativo, entre mayo y septiembre de 2013 en diez hospitales. Para la recolección de datos se utilizó un cuestionario estructurado y los análisis por medio de la estadística descriptiva. Resultados: el envase del dispositivo médico se da en armarios cerrados (60%), con revestimiento lavable (100%), con control de la humedad relativa y la temperatura del aire. El control de la fecha de caducidad de los productos mencionados en todos los centros de material y esterilización y el transporte en automóviles exclusivos en un 80%; 30% no tenía espacio físico exclusivo para productos estériles, y los almacena junto con los materiales no estériles. Conclusión: Existe una necesidad de una mayor atención a la conservación del producto para la salud y el cumplimiento de la legislación vigente.Descriptores: Sustancia de almacenamiento, Productos y materiales, Esterilización, Enfermería, Seguridad del Paciente.

scholarly journals Errors That Occur from Using an Inappropriate Thermal Buffer When Monitoring the Storage Conditions of Temperature Sensitive Products: Size and Material DO Matter

2018 ◽  
Vol 9 (2) ◽  
pp. 16
Author(s):  
Michael Richard Rusnack
Keyword(s):  
Thermal Properties ◽  
Air Temperature ◽  
Cold Storage ◽  
Storage Conditions ◽  
Complex Problem ◽  
Cold Chain ◽  
Original Research ◽  
Temperature Sensitive ◽  
Storage Unit ◽  
Chain Conditions

Common practice in the monitoring of cold chain conditions for temperature sensitive products is to employ a physical thermal buffer into which the temperature probe is inserted. This buffer may be a bottle of glycol or other liquid, a container of glass beads, aluminum block or nearly any other media the user feels appropriate. The purpose of the buffer is to simulate the experience of the stored product rather than the air temperature. Obviously, this mission will not be accomplished to the extent that the physical buffer is not matched to the thermal properties of the stored product and its container. Cold chain managers are faced with a complex problem if they attempt to take this issue into account. Furthermore, a match is not possible with a single physical buffer when the cold storage unit contains different products or size containers. This paper quantifies the results of this mismatch from various factors and suggests possible solutions to this dilemma.   Type: Original Research

Picture Recognition Errors in the Differential Diagnosis of Alzheimer’s Disease

2019 ◽  
Vol 30 (3) ◽  
pp. 157-168
Author(s):  
Helmut Hildebrandt ◽  
Jana Schill ◽  
Jana Bördgen ◽  
Andreas Kastrup ◽  
Paul Eling
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Differential Diagnosis ◽  
Clinical Diagnosis ◽  
Response Bias ◽  
Recognition Task ◽  
Discriminatory Power ◽  
False Alarms ◽  
Picture Recognition ◽  
Recognition Errors

Abstract. This article explores the possibility of differentiating between patients suffering from Alzheimer’s disease (AD) and patients with other kinds of dementia by focusing on false alarms (FAs) on a picture recognition task (PRT). In Study 1, we compared AD and non-AD patients on the PRT and found that FAs discriminate well between these groups. Study 2 served to improve the discriminatory power of the FA score on the picture recognition task by adding associated pairs. Here, too, the FA score differentiated well between AD and non-AD patients, though the discriminatory power did not improve. The findings suggest that AD patients show a liberal response bias. Taken together, these studies suggest that FAs in picture recognition are of major importance for the clinical diagnosis of AD.

How do automation false alarms and misses affect operator compliance and reliance?

2006 ◽  
Author(s):  
Stephen R. Dixon ◽  
Christopher D. Wickens ◽  
Jason S. McCarley
Keyword(s):  
False Alarms

A Brief Meditation Reduces False Alarms to Non-Living Lures

2013 ◽  
Author(s):  
Angelica Szani ◽  
Katherine Bowers ◽  
Lucienne Pereira-Pasarin ◽  
Marianne E. Lloyd
Keyword(s):  
False Alarms

Evaluation of Microbial Load from Canned Soya Milk Drinks in Malaysia

2016 ◽  
Vol 2 (1) ◽  
pp. 22-25
Author(s):  
Nur Amalina binti Mustafa ◽  
Muhammad Ashraf bin Redzuan ◽  
Muhamad Hazim bin Zuraimi ◽  
Muhamad Shuhaimi bin Shuib ◽  
Shahnaz Majeed ◽  
...  
Keyword(s):  
Culture Media ◽  
Storage Condition ◽  
Storage Conditions ◽  
Nutrient Agar ◽  
Microbial Load ◽  
Blood Agar ◽  
Human Consumption ◽  
Processing Unit ◽  
Soya Milk ◽  
Two Samples

Objective: Owing to the habit of consuming ready food among the citizens of Malaysia a study was conducted to evaluate 20 samples of canned soya milk for the presence of possible microbial content. The samples were collected randomly from shopping malls, restaurants and kiosk in Ipoh Malaysia. Methods: All samples collected across Ipoh, were subjected to test for presence bacteria in nutrient agar, blood agar and macConkey media. The possible microbial load was swapped from surface and soya milk content with a sterile cotton and streaked on nutrient agar, blood agar and macConkey culture media. The streaked petri plates were incubated for 48 hours at 37oC. Results: The study revealed negative microbial growth in all except two samples from the surface and soya milk content collected from a restaurant in nutrient agar and blood agar medium. The presence of microbes was conformed as gram positive staphylococcus sp. through gram staining. The positive growth may be imputed to poor storage condition at the restaurant. Conclusion: It can be computed from the study that the majority of the samples were free from bacterial growth, suggesting strong in house quality control mechanism at the processing unit and exquisite storage conditions in malls and kiosk suggesting that soya milk available in malls and kiosk are fit for human consumption.

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