scholarly journals Prevalence of nodular goiter in patients with breast diseases

2020 ◽  
Vol 5 (2) ◽  
pp. 91-95
Author(s):  
Gurushantappa Yalagachin ◽  
◽  
Nishanth Lakshmikantha ◽  
Sanjay B. Mashal ◽  
◽  
...  
Keyword(s):  
Thyroid Disease ◽  
Nodular Goiter ◽  
Breast Disease ◽  
Thyroid Diseases ◽  
Breast Diseases ◽  
Benign Breast Diseases ◽  
Thyroid Screening ◽  
Diffuse Goiter ◽  
Malignant Breast ◽  
Thyroid Profile

Introduction. Various studies have reported conflicting results regarding the relationship between breast and thyroid diseases. The exact pathogenesis behind this association is not clear. The aim of this study was to determine the prevalence of thyroid disease in patients presenting with breast diseases and to examine whether thyroid screening is required in patients with breast diseases. Methodology. All patients attending the department of General Surgery in our institution with breast diseases during the period from December 2015 to September 2017 were enrolled for the study. A thorough clinical examination which included an examination of the neck was done. Thyroid profile and ultrasonography neck were performed in all patients and the pathology in all radiologically diagnosed cases of nodular goiter was confirmed by cytology. Results. We had 128 patients with breast diseases enrolled in the study of which 62 (48%) patients had malignant breast disease and 66 (52%) patients had benign breast disease. None of the patients in our study had a palpable thyroid nodule or a diffuse goiter. Of the 61 patients having malignant breast diseases, 26 (42.6%) patients had a radiologically detected thyroid disease and among the 64 patients with benign breast diseases, 10 (15.6%) had radiologically detected thyroid diseases. Conclusions. In our study the prevalence of nodular goiter was higher in patients with malignant breast diseases than patients with benign breast diseases. However, this prevalence or clinical relevance is not significant enough to warrant screening for thyroid disease in patients with breast diseases.

scholarly journals Spectrum of Breast Diseases in Females- a 10 years study

2018 ◽  
Vol 9 (1) ◽  
pp. 10-12
Author(s):  
Shakera Ahmed ◽  
Sami Ahmad ◽  
Nadim Ahmed ◽  
Nur Mohommad Sayed Bin Aziz
Keyword(s):  
Benign Breast Disease ◽  
Breast Disease ◽  
Breast Diseases ◽  
Historical Cohort ◽  
Female Patients ◽  
Benign Breast Diseases ◽  
Fibrocystic Change ◽  
Malignant Breast ◽  
The Common ◽  
Set Up

Objective: To determine the frequency of various breast diseases in female patients.Methodology: This is a prospective (historical)cohort study of female patients from 18 to 55 years of age visiting a female surgeon with breast problems. The study was conducted at Chittagong Metropoliton Hospital and CSCR Hospital in Chittagong over a period of 10 years starting from July 2007 to June 2017. All female patients visiting with breast problems were included in the study, excluding the patients of below 18 years and above 55 years. The findings were tabulated in excel sheet and analyzed for the frequency of each lesion.Results: A total of 3555 patients were included in the study. Benign breast disease (BBD) was much more common than the malignant breast disease which was 3.49% (124/3555) of all breast diseases. Fibroadenoma was the most common benign breast disease, seen in 32.26%(1147/3555) of patients followed by mastalgia, seen in 24.22%(861) patients. The next common breast disease is fibrocystic change in 18.80%(668/3555) patients.Conclusion: Breast diseases, both benign and malignant are the common problems of female. But benign breast diseases are much more common than the malignant diseases. Fibroadenoma is the commonest of all benign breast diseases in our set up. Mastalgia and fibrocystic changes are the next two common diseases.J Shaheed Suhrawardy Med Coll, June 2017, Vol.9(1); 10-12

scholarly journals Study of various benign breast diseases

2016 ◽  
Vol 4 (1) ◽  
pp. 339 ◽  
Author(s):  
S. Selvakumaran ◽  
Mimamaychet B. Sangma
Keyword(s):  
Benign Breast Disease ◽  
Breast Disease ◽  
Breast Diseases ◽  
Benign Lesions ◽  
Benign Breast Diseases ◽  
Wide Range ◽  
Breast Condition ◽  
Chronic Abscess ◽  
Malignant Breast ◽  
Self Examination

Background:Benign breast disorders can be defined as any non-malignant breast condition and encompasses a wide range of clinical and pathological disorders. BBD are very common and 1/3rd of women are suffering from this disorder in one time of their life. The aim of this study is to look at the patterns of benign breast diseases, the mode of presentation, management and to identify risk factors.Methods: This descriptive study was done in 168 patients presented to the surgery OPD department with benign breast disorders. All the patients with breast related disease were included in this study. Both male and female patients were included in this study. Patients with obvious or biopsy proven malignant diseases were excluded in this study.Results:The study comprised of 168 patients with BBD; the commonest being Fibroadenoma which formed 55.9% followed by fibroadenosis 20.8%. The other benign lesions observed were cystosarcoma phylloids, acute abscess, chronic abscess, tuberculous mastitis, antibioma, cysts, galactocele, gynaecomastia, traumatic fat necrosis, duct papilloma and mastalgia.Conclusions:Benign breast disease is a neglected entity despite the fact that it constitutes the majority of breast complaints. Benign breast disease can no longer be ignored. Much more work needs to be done to collect data about the incidence and prevalence of benign breast diseases. Breast self-examination and education to the females is required for early diagnosis and prompt treatment as majority of anxiety and worry of having breast cancer can be alleviated.

Impact of the serum thyroglobulin concentration on the diagnostics of benign and malignant thyroid diseases

2000 ◽  
Vol 39 (05) ◽  
pp. 133-138 ◽  
Author(s):  
W. Dembowski ◽  
H.-J. Schroth ◽  
K. Klinger ◽  
Th. Rink
Keyword(s):  
Hashimoto’S Thyroiditis ◽  
Thyroid Volume ◽  
Nodular Goiter ◽  
Thyroid Diseases ◽  
Hashimoto's Thyroiditis ◽  
Graves Disease ◽  
Normal Range ◽  
Serum Thyroglobulin ◽  
Diffuse Goiter ◽  
Hyperthyroid Patients

Summary Aim of this study is to evaluate new and controversially discussed indications for determining the thyroglobulin (Tg) level in different thyroid diseases to support routine diagnostics. Methods: The following groups were included: 250 healthy subjects without goiter, 50 persons with diffuse goiter, 161 patients with multinodular goiter devoid of functional disorder (108 of them underwent surgery, in 17 cases carcinomas were detected), 60 hyperthyroid patients with autonomously functioning nodular goiter, 150 patients with Hashimoto’s thyroiditis and 30 hyperthyroid patients with Graves’ disease. Results: The upper limit of the normal range of the Tg level was calculated as 30 ng Tg/ml. The evaluation of the collective with diffuse goiter showed that the figure of the Tg level can be expected in a similar magnitude as the thyroid volume in milliliters. Nodular tissue led to far higher Tg values then presumed when considering the respective thyroid volume, with a rather high variance. A formula for a rough prediction of the Tg levels in nodular goiters is described. In ten out of 17 cases with thyroid carcinoma, the Tg was lower than estimated with thyroid and nodular volumes, but two patients showed a Tg exceeding 1000 ng/ml. The collective with functional autonomy had a significantly higher average Tg level than a matched euthyroid group being under suppressive levothyroxine substitution. However, due to the high variance of the Tg values, the autonomy could not consistently be predicted with the Tg level in individual cases. The patients with Hashimoto’s thyroiditis showed slightly decreased Tg levels. In Graves’ disease, a significantly higher average Tg level was observed compared with a matched group with diffuse goiter, but 47% of all Tg values were still in the normal range (< 30 ng/ml). Conclusion: Elevated Tg levels indicate a high probability of thyroid diseases, such as malignancy, autonomy or Graves’ disease. However, as low Tg concentrations cannot exclude the respective disorder, a routine Tg determination seems not to be justified in benign thyroid diseases.

Benign Breast Disease

2017 ◽  
Author(s):  
Stephanie A Valente ◽  
Stephen R Grobmyer
Keyword(s):  
Benign Breast Disease ◽  
Nipple Discharge ◽  
Breast Disease ◽  
Breast Diseases ◽  
Breast Pain ◽  
Idiopathic Granulomatous Mastitis ◽  
Breast Cyst ◽  
Benign Breast Diseases ◽  
Palpable Breast ◽  
Management Recommendations

Benign breast disease constitutes any abnormality that upon further workup is found to be noncancerous and does not establish premalignant potential. Benign breast diseases can present in various ways, such as breast pain, a palpable breast lump, nipple discharge, or an imaging abnormality. Appropriate workup is essential to ensure that the new change is benign. This may entail additional imaging, biopsy, or surgery if necessary. Surgeons need to be able to recognize the presentation, appropriate workup, and treatment recommendations for the various benign breast diseases. This review addresses the broad range of benign breast lesions and their management recommendations.  This review contains 7 figures, 5 tables and 54 references Key words: benign breast disease, breast cyst, breast mass, breast pain, idiopathic granulomatous mastitis, nipple discharge, papilloma, periductal mastitis, sclerosing adenosis

scholarly journals Prevalence of thyroid diseases in patients with acromegaly: experience of a Brazilian center

2013 ◽  
Vol 57 (9) ◽  
pp. 685-690 ◽  
Author(s):  
Helena Bandeira de Melo Paiva Uchoa ◽  
Giovanna Aparecida Balarini Lima ◽  
Lívia Lugarinho Corrêa ◽  
Ana Paula Sieiro Vidal ◽  
Suzana Aquino Cavallieri ◽  
...  
Keyword(s):  
Thyroid Volume ◽  
Nodular Goiter ◽  
Needle Aspiration ◽  
Thyroid Diseases ◽  
Thyroid Disorders ◽  
Free T4 ◽  
Age Related ◽  
Igf I ◽  
Diffuse Goiter ◽  
Antibody Levels

OBJECTIVES: Acromegaly is frequently associated with thyroid diseases. In this study, we evaluated the frequency of thyroid disorders in a series of acromegalic patients. SUBJECTS AND METHODS: We evaluated 106 acromegalic patients using thyroid ultrasonography (US) and measurements of GH, IGF-I, free T4, TSH and anti-thyroperoxidase antibody levels. IGF-I was expressed in mass units and age-related standard deviation scores (SD-scores). Fine-needle aspiration biopsy (FNAB) was performed on thyroid nodules with a diameter greater than one centimeter or with suspicious characteristics. RESULTS: Thyroid disorders were found in 75 patients. Eleven patients had diffuse goiter, 42 patients had nodular goiter, and 22 patients had unspecific morphological abnormalities. Four patients (3.8%) had thyroid carcinoma. Considering the patients with diffuse or nodular goiter, thyroid volume was greater in patients with active acromegaly, and was positively correlated with GH, IGF-I, and IGF-I SD-score. CONCLUSIONS: Our study confirmed that benign thyroid diseases are frequent in acromegalic patients. The prevalence of thyroid cancer was higher than in the overall population. We suggest that thyroid US should be routinely performed in patients with acromegaly.

scholarly journals Clinicopathological study of benign breast diseases a study of 50 cases

2021 ◽  
Vol 8 (5) ◽  
pp. 1462
Author(s):  
Manish Chaudhary ◽  
Purvesh Bhat ◽  
Vedant Wankhede ◽  
Jigar Aagja ◽  
Dhaval Rathva ◽  
...  
Keyword(s):  
Breast Diseases ◽  
Age Group ◽  
Medical College ◽  
Benign Breast Diseases ◽  
Fibrocystic Change ◽  
Wide Range ◽  
Breast Condition ◽  
Malignant Breast ◽  
Male Patients ◽  
The Given

Background: Benign breast diseases are a neglected entity in developing countries despite the fact that they involved in the majority of breast complaints. Benign breast disorders can be defined as any non-malignant breast condition and involved wide range of clinical and pathological disorders. Breast diseases present as swellings. It is a symptom/sign for a different lesion varying from developmental abnormality, inflammatory lesions, epithelial and stromal proliferation to malignancy. Patients were studied on the basis of i.e., clinically, and histopathological ultrasound has done. Our purpose of study is to document various benign Brest diseases to study different mode of presentations of diseases and correlation of clinical and pathological diagnosisMethods: The given study was a prospective and observational study, undertaken in the department of general surgery, govt. medical college Surat, during the study period of March 2018 to September 2019.All the female and male patients with breast related disease were included in this study. Female patients with biopsy proven malignancy were excluded from the study.Results: The study comprised of 50 patients with benign breast diseases; the most common is Fibro adenoma which formed 68% then fibrocystic diseases 20%. With most common age group involved in our study is 21-30 years.Conclusions: Benign breast diseases are more common but ignored entity though it carries majority of complaints and occur mainly in young women less than 30 years of age and were mostly fibro adenoma and fibrocystic change.

scholarly journals Breast Evaluation Findings in Calabar, Nigeria

2014 ◽  
Vol 2 (4) ◽  
pp. 650-654
Author(s):  
Anthonia Ikpeme ◽  
Akintunde Akintomide ◽  
Grace Inah ◽  
Afiong Oku
Keyword(s):  
Breast Disease ◽  
Breast Diseases ◽  
Outer Quadrant ◽  
Tertiary Institutions ◽  
X Ray ◽  
The Past ◽  
Significant Difference ◽  
Malignant Breast ◽  
Developed World ◽  
Do So

BACKGROUND:  X-ray and sonomammography constitute a significant option in the early detection and management of breast diseases in the developed world. Unfortunately these modalities became available in Nigeria, only in the past few decades.AIM: The aim of this audit is therefore to document the imaging findings, in the past three years in a developing facility in Nigeria relating them with the demograghic features.METHODS: We prospectively studied the x-ray and sonomammography in all patients, presenting over a three year period, for breast evaluation with the hope of discerning the epidemiologic pattern of breast lesions in this environment.RESULTS: One hundred and forty-five females and four males. Median was 38 years (IQR=30-48). The commonest reason for evaluation was screening. Patients that were below 38 years showed no significant difference in frequency and type of lesion compared with patients over 38 years. The commonest breast pattern was fatty replaced. The upper outer quadrant was the commonest site.CONCLUSION: Patients presenting for breast evaluation in Calabar do so for screening mainly. Patients below 38 are nearly equally affected by malignant breast disease as their older counterparts. The commonest breast pattern was fatty replaced. Digital mammography should be available in all tertiary institutions.

scholarly journals Profile of benign breast disease in Kashmiri women: a prospective study

2017 ◽  
Vol 4 (6) ◽  
pp. 1973
Author(s):  
Mumtazdin Wani ◽  
Shabir Ahmad Mir ◽  
Mohammad Hanief Dar
Keyword(s):  
Prospective Study ◽  
Benign Lesion ◽  
Breast Disease ◽  
Breast Diseases ◽  
Symptom Duration ◽  
Duration Of Symptoms ◽  
Benign Breast Diseases ◽  
Predominant Symptom ◽  
Breast Lumps ◽  
The Right

Background: Though benign breast diseases are very common, not many studies have focussed on this entity. In Kashmir valley, no major study has been undertaken before, to look into the profile of the benign breast diseases in women.Methods: This prospective study was conducted in the Postgraduate Department of General Surgery of SMHS Hospital from October 2012 to September 2014. The patients with features of benign breast diseases were subjected to detailed history, clinical examination and investigations. Analysis was done using this data.Results: 80% of the benign breast lesions presented in the second and third decades of life. Mean age was 24.46 years. Most common benign breast lesion was fibroadenoma. Lump in the breast was the predominant symptom. Duration of symptoms mostly ranged from 1 to 6 months. There was a slight preponderance of lesions in the right breast. Most of lesions presented in upper outer quadrant.  81.39% of the patients had only a solitary lump.76.74% of lumps had a size of 2 to 5cm. Clinicopathological correlation in case of fibroadenoma, showed 60% sensitivity, 75% specificity, PPV=85.71% and NPV=42.85%. Cytohistological correlation in case of fibroadenoma, showed 85% sensitivity, 87.5% specificity, PPV=94.4% and NPV=70%. 38 cases (38%) were managed conservatively and 62 cases (62%) were managed surgically.Conclusions: Results grossly similar to other parts of the word were obtained. Fibroadenoma was the most common benign lesion encountered followed by fibroadenosis and breast abscess. Majority of breast lumps were painless. Conservative approach for fibroadenoma is acceptable option in the adolescents.

STUDY ON PATTERN AND PREVALENCE OF BENIGN BREAST DISEASE IN NORTH INDIA

2021 ◽  
pp. 63-64
Author(s):  
Anurag Khare ◽  
Raj Awasthi
Keyword(s):  
Benign Breast Disease ◽  
Tertiary Care ◽  
Breast Disease ◽  
North India ◽  
Breast Diseases ◽  
Western India ◽  
Breast Lesions ◽  
Care Hospital ◽  
Benign Breast Diseases ◽  
Benign Breast Lesions

Background: Benign breast diseases constitute a heterogeneous group of disorders including developmental abnormality, epithelial and stromal proliferation, inammatory lesions and neoplasm. Benign breast lesions deserve attention because of their high prevalence, their impact on women's life and due to cancerous potential of some histological types. Treatment of BBDS is preservation of breast tissue as far as possible in contrast to traumatizing mutilating surgeries in breast cancers. Objectives:To study pattern and presentation of benign breast lesions over a period of 1 year in a tertiary care hospital of Lucknow, Uttar Pradesh. Material and Methods: This study of 180 cases of histologically diagnosed benign breast lesions was carried out in the Department of Pathology, at tertiary care teaching hospital with attached peripheral hospitals in a metropolitan city of western India from August 2018 to July 2019. Results: Out of 180 benign lesions, 175 (97.2%) were found in females and 05 (2.8%) were found in males. Commonest benign breast lesion was broadenoma (86.1%), followed by brocystic disease (2.2%) and gynaecomastia (2.8%). Conclusion: Fibroadenoma is the most common benign breast disease. Most of the patients presented with painless lump in the breast in upper outer quadrant of the breast. Histopathology plays an important role in the diagnosis of benign breast diseases.

scholarly journals Age and Gender Distribution of Benign Breast Lesions of Women at Port City of Bangladesh

2018 ◽  
Vol 16 (1) ◽  
pp. 27-31
Author(s):  
Nazmun Nahar ◽  
Mohammed Iqbal ◽  
Kazi Md Shahidur Rahman ◽  
Sabrina Razzaque ◽  
Farida Yeasmin ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Nipple Discharge ◽  
Benign Neoplasm ◽  
Breast Disease ◽  
Pathological Examination ◽  
Breast Diseases ◽  
Cross Sectional ◽  
Medical College ◽  
Benign Breast Diseases ◽  
Triple Assessment

Background: Benign breast diseases are the most common cause of breast problems. The most common symptoms are breast pain, lumpiness or a lump and nipple discharge. Triple assessment that includes clinical examination, imaging like ultrasonography (USG) or mammography and a pathological examination – FNAC or core needle biopsy has a very high accuracy rate in diagnosing, discrete benign breast diseases and this can be used for reassurance.Objective: The purpose of the present study was to determine the frequency of different types of benign neoplasm of breast lump in different age and sex.Methodology: The present study was carried out at the Department of Pathology, Chittagong Medical College, Bangladesh one year period from May 2005 to June 2006. This study was cross sectional which included 48 cases of breast neoplasm. The specimens were received from indoor patient Department of Surgery, Chittagong Medical College, Bangladesh. Histopathological examination was done.Results: This study shows the mean age of the patients was 32.91 years with age range 11 to 70 years. Most of the patients were in 31 to 50 years (45.8%) age group and female predominance than male. Fibroadenoma accounted for 76.2%. Sclerosing adenosine the second most common benign breast disease in this study accounted for 9.5% of cases.Conclusion: This study showed that among the benign breast diseases in females there were preponderance of fibroadenoma followed by sclerosing adenosineJournal of Science Foundation 2018;16(1):27-31

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