scholarly journals Laterality and site-specific distribution patterns of Lentigo Maligna and Lentigo Maligna Melanoma

2021 ◽  
Vol 5 (5) ◽  
pp. 530-532
Author(s):  
Gabrielle Brody ◽  
Katerina Yale ◽  
Alora Nguyen ◽  
Margit Juhasz ◽  
Linda Doan ◽  
...  

Background: Melanoma has been described to have preferential left-sided laterality on the human body. The distribution and invasion patterns of lentigo maligna (LM) and lentigo maligna melanoma (LMM) have not been well described. Methods: This was a cross-sectional, retrospective study at a single, academic center. LM and LMM cases from 2008-2018 in the dermatopathology registry were analyzed. Results: A total of 392 cases were included (241 LM and 151 LMM). There was no laterality preference overall. The only exception were neoplasms located on the head/neck, which showed a left-sided laterality. LM and LMM had the highest incidence on the head/neck, followed by upper extremities, trunk, then lower extremities. Men had a higher incidence on the head/neck and trunk, while women had a higher incidence on the extremities. Interestingly, the upper extremities and the right side of the female body had a higher propensity for invasive lesions. Conclusion: While melanomas demonstrate preferential left-sided laterality, LM and LMM only share this pattern in respect to the head/neck region. Our results complement previous study findings which characterize LM and LMM as a head/neck and upper extremity pathology. Finally, our study suggests that certain body sites and laterality have an increased propensity for invasion.

2017 ◽  
Vol 22 (1) ◽  
pp. 51-57 ◽  
Author(s):  
Marisa Grace Ponzo ◽  
Richard Ian Crawford ◽  
Irèn Kossintseva

Amelanotic lentigo maligna melanoma represents <2% of melanomas. Diagnosis is delayed owing to the lack of lesion pigmentation and advanced disease at presentation. Excision with appropriate margins is the treatment standard, but the starting point for such margins is often unclear. We describe 2 patients with amelanotic melanoma treated by Mohs micrographic surgery (MMS) that would not have been cleared by wide local excision alone and provide an extensive review of the literature. Both patients presented with histologic diagnoses of malignant melanoma, one with a barely perceptible biopsy site scar on the left infraorbital cheek/lower eyelid (Breslow 1.8 mm) and the second with an amelanotic tumour on the right helix (Breslow 10 mm). Due to location, aggressive histology, amelanotic appearance, and no apparent surrounding skin surface changes, MMS was elected to maximise margin control. For patient 1, invasive and in situ tumour was found at the American Joint Committee on Cancer–recommended margin of 1.5 cm, and the final defect measured 8.5 × 4.8 cm. Patient 2 had a significant invasive and amelanotic lentigo maligna component, resulting in a 9.0 × 6.5-cm defect. MMS allows for immediate histologic feedback on tumour margins of a clinically invisible tumour and thus offers the most definitive treatment.


2018 ◽  
Vol 5 (6) ◽  
pp. 2292
Author(s):  
Parvez Mujawar ◽  
Dhiraj B. Nikumbh ◽  
Nandkumar V. Dravid ◽  
Ravi Prabhat

Background: Epidermoid inclusion cysts are common benign lesions of the pilosebaceous origin that encountered anywhere in the body. Most common sites are hairy and non hairy areas mainly scalp, back, neck and trunk. Objective of present study was to highlight and document the cytohistomorphological features of epidermoid inclusion cysts (EIC) at unusual locations of the body in our tertiary care center.Methods: The present study is retrospective, cross sectional study done on cytohistopathological specimen over a period of 30 months from June 2016 to December 2017. A total of 82 cases of EIC were included in the study. All the sites were included in the study that is usual as well as unusual. Sebaceous and dermoid cysts were excluded from the study. Unusual sites of EIC were collected, tabulated and compared with existing literature.Results: The most common affected site of EIC in our study was head, neck and face (42.7%) followed by extremities and axilla (29%), back (11%) and chest/abdomen (8.6%). Peak incidence of EIC was found in 31 to 40 years (34.1%) with male preponderance (1.5:1). The unusual sites encountered were oral cavity and tonsil in head neck region, sole in the extremities, breasts and testis.Conclusions: The study highlights the importance of FNAC in early diagnosis and histopathology for confirmation and treatment purposes in epidermoid inclusion cysts. It provides prompt response to avoid cosmetic and functional disabilities in unusual locations of common lesions like EIC because the differentials may from inflammatory to malignant ones.


2014 ◽  
Vol 34 (2) ◽  
pp. 141-143
Author(s):  
Ali Kanik ◽  
Kayi Eliacik ◽  
Tolga Ince ◽  
Umit Bayol ◽  
Mehmet Helvacı

Nodular fasciitis is a benign, reactive proliferation of fibroblasts in the subcutaneous tissues. It usually affects the trunk and upper extremities, and rarely the head and neck region of young adults. It is rare among children and the histologic findings may incorrectly suggest malignant lesions. We describe a two-year-old girl that referred to our clinic with complaints of fever and swelling on the right side of neck and diagnosed as lymphadenitis clinically. Cervical lymphadenitis due to nodular fasciitis is a rarity. We emphasize that nodular fasciitis needs to be included in the differential diagnoses of neck lymphadenitis during childhood. DOI: http://dx.doi.org/10.3126/jnps.v34i2.9548J Nepal Paediatr Soc 2014;34(2):141-143 


2020 ◽  
Vol 23 (01) ◽  
pp. 2050002
Author(s):  
Ghorbanali Mohammadi

Musculoskeletal symptoms are the most frequent occupational health problems and accounts for a large number of losses in working days and disability for workers in modern industrialization. The aim of this paper was to investigate the relationship between the self-reported prevalence of musculoskeletal symptoms in the head/neck, upper back and lower back and certain individual, work- related physical, psychological and general health factors. A cross-sectional study was conducted using a descriptive questionnaire which was distributed to 350 oil refinery workers in Iran and collected between April to December 2016. A total of 282 workers returned completed questionnaire, yielding a response rate of 81%. For the head/neck region, working at the long periods in uncomfortable posture (adjusted [Formula: see text], 95% [Formula: see text]–2.58) and doing repetitive activity (adjusted [Formula: see text], 95% [Formula: see text]–2.67) increased the risk experiencing head/neck symptoms. For the upper back region, lifting and transferring during work increased the risk of experiencing upper back symptoms (adjusted [Formula: see text], 95% [Formula: see text]–2.79). For the lower back region, working for more than 8[Formula: see text]h a week shows the strongly significant association for the risk of lower back symptoms. Lower back pain was associated with symptoms of anxiety and dysfunction in social functioning. Some physical and psychological factors were associated with the prevalence of musculoskeletal symptoms in the spine among oil refinery workers. These data emphasize the need to develop and implement preventive measures that reduce the prevalence of musculoskeletal symptoms among workers.


2017 ◽  
Vol 6 (3) ◽  
pp. 186-194
Author(s):  
Deby Zulkarnain Rahadian Syah ◽  
Muhamat Nofiyanto

Background: Nurses in charge of the Emergency Room are required to have more ability than nurses serving patients in other units. Emergency Room is an initial service in a hospital. One's leadership style will greatly affect the effectiveness of a leader. The selection of the right leadership style can lead to the achievement of individual or organizational goals. Objective: To know the various leadership style used by the head of room in improving the performance of nurses of Emergency Room RSUD in in Special Region of Yogyakarta. Method: This research includes quantitative research type, using cross sectional approach. The population of this study was the head of the treatment room. Secondary data of nurse's performance is taken from nursing care which is written in medical record file of Emergency Room of RSUD in Special Region of Yogyakarta. Results: The performance of nurses at Emergency Room RSUD A in the good category was 100%. The performance of nurses at Emergency Room RSUD B in the enough category was 45%. The performance of nurses at Emergency Room C in good category was 80%. The performance of nurses at Emergency Room RSUD D in good category was 55%. The performance of nurses at RSUD E in the good category was 95%. The result of cross tabulation between leadership style and nurse performance of RSUD in the whole DIY with good performance is leader who use democratic leadership style equal to 35%. Conclusion: Most of the nurse's good performance in Emergency Room is followed by democratic leadership style of head of space.  Keyword: leadership style, head of space, performance of nurses


2020 ◽  
Author(s):  
Kristin Natal Riang Gea

AbstrakKeselamatan pasien merupakan dasar dari pelayanan kesehatan yang baik. Pengetahuan tenaga kesehatan dalam sasaran keselamatan pasien terdiri dari ketepatan identifikasi pasien, peningkatan komunikasi yang efektif, peningkatan keamanan obat yang perlu diwaspadai, kepastian tepat lokasi, prosedur, dan tepat pasien operasi, pengurangan risiko infeksi, pengurangan risiko pasien jatuh. Tujuan penelitian untuk mengetahui hubungan antara pengetahuan dengan penerapan keselamatan pasien pada petugas kesehatan di Puskesmas Kedaung Wetan Kota Tangerang. Metode Penelitian menggunakan deskriptif korelasi menggunakan pendekatan cross sectional. Populasi sebanyak 50 responden. Teknik pengambilan sampel menggunakan total sampling. Instrumen yang digunakan berupa lembar kuesioner. Teknik analisa diatas menggunakan analisa Univariat dan Bivariat. Hasil Penelitian ada Hubungan Pengetahuan dengan Penerapan Keselamatan Pasien pada Petugas Kesehatan, dengan hasil, p value sebesar 0,013 &lt; 0,05 maka dapat disimpulkan bahwa ada Hubungan Pengetahuan dengan Penerapa Keselamatan Pasien pada Petugas Kesehatan. Kesimpulan penelitian ada Hubungan Pengetahuan dengan Penerapan Keselamatan Pasien.. AbstrackPatient safety is the basis of good health services. Knowledge of health personnel in patient safety targets consists of accurate patient identification, increased effective communication, increased safety of the drug that needs to be watched, certainty in the right location, procedure, and precise patient surgery, reduction in risk of infection, reduction in risk of falling patients. The purpose of this study was to determine the relationship between knowledge and the application of patient safety to health workers in the Kedaung Wetan Health Center, Tangerang City. The research method uses descriptive correlation using cross sectional approach. The population is 50 respondents. The sampling technique uses total sampling. The instrument used was a questionnaire sheet. The analysis technique above uses Univariate and Bivariate analysis. The results of the study there is a Relationship of Knowledge with the Implementation of Patient Safety in Health Officers, with the result, p value of 0.013 &lt;0.05, it can be concluded that there is a Relationship between Knowledge and Patient Safety Implementation in Health Officers. The conclusion of the study is the Relationship between Knowledge and the Implementation of Patient Safety.Keywords Knowledge, Patient safety, Health workers


2014 ◽  
Vol 12 (2) ◽  
pp. 24-30
Author(s):  
Simone Christensen Hald ◽  
Ditte Aagaard Sondergaard

Background In 2002, the Nepalese abortion law went from being highly restrictive to fully liberal. This study aimed to explore a local community’s perception of the situation for unmarried Nepalese women wanting to practice their legal right to abortion.Methods The study comprised a cross-sectional survey and in-depth interviews with men and women above the age of 16 years living in the Makwanpur District, Nepal. The final data included 55 questionnaires and 16 interviews. The questionnaire data was univariate analysed, while a condensation of meaning analysis was carried out on the interviews.Results The overall awareness of abortion being legal was high, although the extent of knowledge of the specific legal grounds varied. Unmarried women were believed to have access to abortion services, although they risked stigmatisation due to their marital status. The community attitude towards these women having abortions was very negative, hence it differed from the legal acceptance of all women having the right to abortion. This was explained by societal norms on premarital sexual activity. Generally, the participants felt that changing attitudes would be difficult but possible over time.Conclusion A considerable gap exists between the legal acceptance of abortion and community attitudes when it comes to unmarried women as this group encounters barriers when wanting to practice their right. Therefore, these barriers need to be addressed to allow unmarried Nepalese women access to safe abortion services without the risk of being stigmatised.One possible alternative is educational initiatives such as disseminating information vigorously through mass media to create awareness.DOI: http://dx.doi.org/10.3126/hprospect.v12i2.9869 Health Prospect Vol.12(2) 2013: 24-30


2014 ◽  
pp. 73-77
Author(s):  
Van Chuong Nguyen ◽  
Thi Kim Anh Nguyen

Background: A Research glomerular filtration rate (GFR) of 61 patients with type 2 diabetes mellitus with renal scanning 99mTc-DTPA glomerular filtration rate at the hospital 175. Objective: (1) To study characteristics of imaging of renal function. (2) Understanding the relationship between GFR with blood sugar, HbA1c, blood pressure and albuminuria in patients with type 2 diabetes. Methods: Descriptive, prospective, cross-sectional study. Clinical examination, Clinical tests and 99mTc-DTPA GFR gamma - camera renography for patients. Result: GFR of the study group was 75,4 ± 22,3 ml/phut/1,73m2, the left kidney was 35,0 ± 13,0 is lower than the right kidney and 39,8 ± 11,9; p <0,01. There is no correlation between GFR with blood glucose and HbA1c, the risk of reduced GFR in hypertensive group associated is OR = 6,5 with p<0,01; albuminuria (+) is OR = 4,2 with p <0,01; and disease duration > 10 years is OR = 3,5 with p <0.01. Conclusion: GFR of the left kidneys is lower than the right kidney; correlation decreased GFR associated with hypertension, albuminuria and disease duration. Keywords: GFR, diabetes, albuminuria


Sign in / Sign up

Export Citation Format

Share Document