Livestock manure odor abatement with plant-derived oils and nitrogen conservation with urease inhibitors: A review1

The objective of the present investigation was to evaluate the physical characteristics of the vermicompost and the quality of the purine of the red Californian (Eisenia foetida) using different substrates of feed for these worms. For this purpose, nine treatments were studied: 75% African palm rachis + 25% cattle manure, 50% African palm rachis + 50% cattle manure, 25% African palm rachis + 75% livestock manure, 50% manure of cattle, 50% of manure of cattle, 25% of manure of cattle, 50% of manure of cattle, 50% of manure of cattle, 50% of rach of coconut + 50% of manure of Livestock, 25% coccus rachis + 75% livestock manure. The substrate made up of 50% of rachis of coconut and 50% of livestock manure can be used in nurseries or nurseries for being the one that registered a value of pH 7.3 plus the closest to the neutral compared to the others, besides this (75% of oil palm rachis and 25% of cattle manure) showed a higher content of humic and fulvic acids (0.87 and 0.45 p / p, respectively), compounds that are important for agriculture by stimulating plant growth, in addition to this reflection 0.06% sulfur content, 4.0 ppm boron, 7.0 ppm copper, 47.5 ppm iron, 6.0 ppm manganese, with a presence of microorganisms of the species Trichoderma, Penicillium, Cladosporium sp. in amounts of 1.91x105 UFC / ml, however in this substrate was obtained between 13.3 and 43.5% less liquid slurry in Comparison with other treatments.

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A Study on Reduction Characteristics of Ammonia Gas Generated by Rotary-type Livestock Manure Composting Process

Journal of the Korean Society for Environmental Technology ◽

10.26511/jkset.20.6.5 ◽

2019 ◽

Vol 20 (6) ◽

pp. 418-424

Author(s):

Ji-Hun Jang ◽

Yong-Ho Ok ◽

Go-Su Yang

Keyword(s):

Livestock Manure ◽

Ammonia Gas ◽

Composting Process ◽

Reduction Characteristics ◽

Rotary Type

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Increasing nitrogen conservation by adding urease inhibitor NBPT to chicken compost manure

CHINESE JOURNAL OF ECO-AGRICULTURE ◽

10.3724/sp.j.1011.2010.00643 ◽

2010 ◽

Vol 18 (3) ◽

pp. 643-648

Author(s):

Fa-Bao ZHANG ◽

Wen-Jie GU ◽

Pei-Zhi XU ◽

Kai-Zhi XIE ◽

Shuan-Hu TANG ◽

...

Keyword(s):

Urease Inhibitor ◽

Nitrogen Conservation ◽

Compost Manure

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Sumber Energi Terbarukan dan Pupuk Organik dari Limbah Kotoran Sapi

Dimas Jurnal Pemikiran Agama untuk Pemberdayaan ◽

10.21580/dms.2016.161.898 ◽

2016 ◽

Vol 16 (1) ◽

pp. 191

Author(s):

Mulyatun Mulyatun

Keyword(s):

Community Service ◽

Organic Fertilizer ◽

Appropriate Technology ◽

Cow Manure ◽

Livestock Manure ◽

Knowledge And Skills ◽

Service Programs ◽

The People ◽

Community Service Programs ◽

The Impact

In order to meet households energy needs, one of the groundbreaking efforts that needs to be done is to implement appropriate technology training in utilization of cow manure waste by recycling it into biogas and organic fertilizer. Animal husbandry in Bambankerep Sub-District of Ngaliyan, Semarang City, are sufficiently developed, however, the use of livestock manure has not been optimal, whereas livestock manure can be used as raw material to produce renewable energy in the form of biogas and organic fertilizer. Furthermore, Limited knowledge and skills of the people in Bambankerep sub-district in the utilization of cow manure waste by recycling it into biogas and organic fertilizer have become the main problem. Steps performed in Community service programs are as follow (1) Socialization of recycling livestock waste into a blessing; (2) training, (3) Monitoring and outreaching. The impact generated from this community service programs, among others are: (1) raising public awareness in the utilization of cow manure waste for biogas alternative energy, (2) increasing knowledge and skills of people in processing cow manure into energy and fertilizer, (3) growing number of business groups in cow manure organic fertilizer processing that are expected can improve the welfare of the people in Bambankerep sub-district, Mijen, Semarang City. Dalam rangka pemenuhan keperluan energi rumah tangga, salah satu upaya terobosan yang perlu dilakukan adalah melaksanakan pelatihan teknologi tepat guna pemanfaatan limbah kotoran sapi menjadi biogas dan pupuk organik. Usaha peternakan di Kelurahan Bambankerep, Ngaliyan Semarang cukup berkembang, tapi pemanfaatan kotoran ternak selama ini belum optimal, padahal kotoran ternak dapat dijadikan sebagai bahan baku untuk menghasilkan energi terbarukan dalam bentuk biogas dan pupuk organik. Keterbatasannya pengetahuan dan keterampilan yang dimiliki masyarakat di Kelurahan Bambankerep mengolah limbah kotoran sapai menjadi biogas dan pupuk organik menjadi permasalahn utama. Tahapan program pengabdian masyarakat yang dilakukan adalah: (1) Sosialisai pemanfaatan limbah kotoran hewan menjadi berkah; (2) pelatihan; (3) Monitoring dan Pendampingan. Dampak yang dihasilkan dari program pengabdian masyarakat ini antara lain: (1) meningkatkan kesadaran masyarakat untuk memanfaatkan limbah kotoran sapi untuk energi alternatif biogas, (2) meningkatnya pengetahuan dan ketrampilan masyarakat bidang pengolahan kotoran sapi menjadi energi dan pupuk, (3) tumbuhnya kelompok usaha pengolahan pupuk organik dari kotoran sapi sehingga diharapkan dapat meningkatkan kesejahteraan masyarakat Kelurahan Bambankerep Ngaliyan Semarang.

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Reactivity of Barbituric, Thiobarbituric Acids and Their Related Analogues: Synthesis of Substituted and Heterocycles-based Pyrimidines

Current Organic Chemistry ◽

10.2174/1385272824999200608134859 ◽

2020 ◽

Vol 24 (14) ◽

pp. 1610-1642 ◽

Cited By ~ 1

Author(s):

Ahmed El-Mekabaty ◽

Hassan A. Etman ◽

Ahmed Mosbah ◽

Ahmed A. Fadda

Keyword(s):

Xanthine Oxidase ◽

Multicomponent Reactions ◽

Biological Activities ◽

Present Review ◽

Urease Inhibitors ◽

Effective Catalyst ◽

Inhibitory Activities ◽

Catalyst Reusability ◽

High Yields ◽

Nano Catalysts

Barbituric, thiobarbituric acids and their related analogs are reactive synthons for the synthesis of drugs and biologically, and pharmaceutically active pyrimidines. The present review aimed to summarize the recent advances in the synthesis of different alkylsubstituted, fused cycles, spiro-, and binary heterocycles incorporated pyrimidine skeleton based on barbituric derivatives. In this sequence, the eco-friendly techniques under catalytic conditions were used for the diverse types of multicomponent reactions under different conditions for the synthesis of various types of heterocycles. Nano-catalysts are efficient for the synthesis of these compounds in high yields and effective catalyst reusability. The compounds are potent antibacterial, cytotoxic, xanthine oxidase inhibitory activities, and attend as urease inhibitors. The projected mechanisms for the synthesis of pyranopyrimidines, benzochromenopyrimidines, chromeno-pyranopyrimidines, spiroxyindoles, oxospiro-tricyclic furopyrimidines, pyrimidine-based monoand bicyclic pyridines were discussed. The potent and diverse biological activities for instance, antioxidant, antibacterial, cytotoxic, and xanthine oxidase inhibitory activities, as well as urease inhibitors, are specified.

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Discovery and Study of the Binding Epitopes of Novel Urease Inhibitors by STD-NMR Spectroscopy and Biochemical Analyses

Letters in Drug Design & Discovery ◽

10.2174/1570180811310060007 ◽

2013 ◽

Vol 10 (6) ◽

pp. 515-521 ◽

Cited By ~ 1

Author(s):

Atia-tul- Wahab ◽

Ajmal Khan ◽

Bishnu P. Marasini ◽

M. Arif Lodhi ◽

Atta-ur- Rahman ◽

...

Keyword(s):

Nmr Spectroscopy ◽

Urease Inhibitors ◽

Std Nmr ◽

Biochemical Analyses

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Synthesis and Structure−Activity Relationship Studies of N-monosubstituted Aroylthioureas as Urease Inhibitors

Medicinal Chemistry ◽

10.2174/1573406416999200818152440 ◽

2020 ◽

Vol 16 ◽

Author(s):

Wei-Wei Ni ◽

Hai-Lian Fang ◽

Ya-Xi Ye ◽

Wei-Yi Li ◽

Li Liu ◽

...

Keyword(s):

Regression Analysis ◽

Mammalian Cells ◽

Intact Cell ◽

Linear Regression Analysis ◽

Positive Control ◽

Acetohydroxamic Acid ◽

Urease Inhibitors ◽

Ic50 Value ◽

Ic50 Values ◽

Low Cytotoxicity

Background: Thiourea is a classical urease inhibitor usually as a positive control, and many N,N`-disubstituted thioureas have been determined as urease inhibitors. However, due to steric hindrance, N,N`-disubstituted thiourea motif could not bind urease as thiourea. On the contrary, N-monosubstituted thioureas with a tiny thiourea motif could theoretically bind into the active pocket as thiourea. Objective: A series of N-monosubstituted aroylthioureas were designed and synthesized for evaluation as urease inhibitors. Methods: Urease inhibition was determined by the indophenol method and IC50 values were calculated using computerized linear regression analysis of quantal log dose-probit functions. The kinetic parameters were estimated viasurface plasmon resonance (SPR) and by nonlinear regression analysis based on the mixed type inhibition model derived from Michaelis-Menten kinetics. Results: Compounds b2, b11and b19 reversibly inhibited urease with a mixed mechanism, and showed excellent potency against both cell-free urease and urease in intact cell, with IC50 values being 90-to 450-fold and 5-to 50-fold lower than the positive control acetohydroxamic acid, respectively. The most potent compound b11 showed IC50 value of 0.060 ±0.004μM against cell-free urease, which bound to urea binding site with a very low KDvalue (0.420±0.003nM) and a very long residence time (6.7 min). Compound b11was also demonstrated having very low cytotoxicity to mammalian cells. Conclusion: These results revealed that N-monosubstituted aroylthioureas clearly bind the active site of urease as expected, and represent a new class of urease inhibitors for the development of potential therapeutics against infections caused by ure-ase-containing pathogens.

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