The organization of effective multi-user operation of hybrid computing systems

Author(s):  
С.И. Смагин ◽  
А.А. Сорокин ◽  
С.И. Мальковский ◽  
С.П. Королёв ◽  
О.А. Лукьянова ◽  
...  

Исследуются вопросы организации многопользовательской работы гибридных вычислительных систем. На примере кластера Центра коллективного пользования Центр данных ДВО РАН, построенного на архитектуре OpenPOWER, рассмотрены особенности функционирования систем подобного класса и предложены решения для организации их работы. С использованием механизма виртуальных узлов проведена адаптация системы диспетчеризации заданий PBS Professional, позволяющая организовать эффективное распределение аппаратных ресурсов кластера между пользовательскими задачами. Реализованное программное окружение кластера с системой комплексного планирования заданий рассчитано на работу с широким перечнем компьютерных приложений, включая программы, построенные с использованием различных технологий параллельного программирования. Для эффективного исполнения в данной среде решений на основе машинного обучения, глубокого обучения и искусственного интеллекта применены технологии виртуализации. С использованием возможностей среды контейнеризации Singularity сформирован специализированный стек программного обеспечения и реализован особый режим его работы в формате единой вычислительной цифровой платформы. Purpose. Improving the technology of machine learning, deep learning and artificial intelligence plays an important role in acquiring new knowledge, technological modernization and the digital economy development.An important factor of the development in these areas is the availability of an appropriate highperformance computing infrastructure capable of providing the processing of large amounts of data. The creation of coprocessorbased hybrid computing systems, as well as new parallel programming technologies and application development tools allows partial solving this problem. However, many issues of organizing the effective multiuser operation of this class of systems require a separate study. The current paper addresses research in this area. Methodology. Using the OpenPOWER architecturebased cluster in the Shared Services Center The Data Center of the Far Eastern Branch of the Russian Academy of Sciences, the features of the functioning of hybrid computing systems are considered and solutions are proposed for organizing their work in a multiuser mode. Based on the virtual nodes concept, an adaptation of the PBS Professional job scheduling system was carried out, which provides an efficient allocation of cluster hardware resources among user tasks. Application virtualization technology was used for effective execution of machine learning and deep learning problems. Findings. The implemented cluster software environment with the integrated task scheduling system is designed to work with a wide range of computer applications, including programs built using parallel programming technologies. The virtualization technologies were used in this environment for effective execution of the software, based on machine learning, deep learning and artificial intelligence. Having the capabilities of the container Singularity, a specialized software stack and its operation mode was implemented for execution machine learning, deep learning and artificial intelligence tasks on a unified computing digital platform. Originality. The features of hybrid computing platforms functioning are considered, and the approach for their effective multiuser work mode is proposed. An effective resource manage model is developed, based on the virtualization technology usage.

Author(s):  
Oleksandr Dudin ◽  
◽  
Ozar Mintser ◽  
Oksana Sulaieva ◽  
◽  
...  

Introduction. Over the past few decades, thanks to advances in algorithm development, the introduction of available computing power, and the management of large data sets, machine learning methods have become active in various fields of life. Among them, deep learning possesses a special place, which is used in many spheres of health care and is an integral part and prerequisite for the development of digital pathology. Objectives. The purpose of the review was to gather the data on existing image analysis technologies and machine learning tools developed for the whole-slide digital images in pathology. Methods: Analysis of the literature on machine learning methods used in pathology, staps of automated image analysis, types of neural networks, their application and capabilities in digital pathology was performed. Results. To date, a wide range of deep learning strategies have been developed, which are actively used in digital pathology, and demonstrated excellent diagnostic accuracy. In addition to diagnostic solutions, the integration of artificial intelligence into the practice of pathomorphological laboratory provides new tools for assessing the prognosis and prediction of sensitivity to different treatments. Conclusions: The synergy of artificial intelligence and digital pathology is a key tool to improve the accuracy of diagnostics, prognostication and personalized medicine facilitation


2021 ◽  
Author(s):  
Lap Yan Wong ◽  
Chun Kit Yip ◽  
Dao Shen Tan ◽  
Wai Lim Ling

Artificial intelligence (AI) techniques have been commonly used to track, predict early warning, forecast trends, and model and measure public health responses. Statistics have traditionally been used to track public health crises. AI-enabled methods, such as machine learning and deep learning–based models, have exploded in popularity recently, complementing statistical approaches. A wide range of medical fields have used various well-developed deep learning algorithms. Surveillance of public health emergencies is one region that has gained greatly from AI advancements in recent years. One of the examples of effectively reacting to public health emergencies is the need for developing AI evidence-based approaches to public health strategies for the scientific community’s response to the COVID-19 pandemic.


2018 ◽  
Vol 15 (1) ◽  
pp. 6-28 ◽  
Author(s):  
Javier Pérez-Sianes ◽  
Horacio Pérez-Sánchez ◽  
Fernando Díaz

Background: Automated compound testing is currently the de facto standard method for drug screening, but it has not brought the great increase in the number of new drugs that was expected. Computer- aided compounds search, known as Virtual Screening, has shown the benefits to this field as a complement or even alternative to the robotic drug discovery. There are different methods and approaches to address this problem and most of them are often included in one of the main screening strategies. Machine learning, however, has established itself as a virtual screening methodology in its own right and it may grow in popularity with the new trends on artificial intelligence. Objective: This paper will attempt to provide a comprehensive and structured review that collects the most important proposals made so far in this area of research. Particular attention is given to some recent developments carried out in the machine learning field: the deep learning approach, which is pointed out as a future key player in the virtual screening landscape.


2020 ◽  
Vol 114 ◽  
pp. 242-245
Author(s):  
Jootaek Lee

The term, Artificial Intelligence (AI), has changed since it was first coined by John MacCarthy in 1956. AI, believed to have been created with Kurt Gödel's unprovable computational statements in 1931, is now called deep learning or machine learning. AI is defined as a computer machine with the ability to make predictions about the future and solve complex tasks, using algorithms. The AI algorithms are enhanced and become effective with big data capturing the present and the past while still necessarily reflecting human biases into models and equations. AI is also capable of making choices like humans, mirroring human reasoning. AI can help robots to efficiently repeat the same labor intensive procedures in factories and can analyze historic and present data efficiently through deep learning, natural language processing, and anomaly detection. Thus, AI covers a spectrum of augmented intelligence relating to prediction, autonomous intelligence relating to decision making, automated intelligence for labor robots, and assisted intelligence for data analysis.


2021 ◽  
Vol 54 (6) ◽  
pp. 1-35
Author(s):  
Ninareh Mehrabi ◽  
Fred Morstatter ◽  
Nripsuta Saxena ◽  
Kristina Lerman ◽  
Aram Galstyan

With the widespread use of artificial intelligence (AI) systems and applications in our everyday lives, accounting for fairness has gained significant importance in designing and engineering of such systems. AI systems can be used in many sensitive environments to make important and life-changing decisions; thus, it is crucial to ensure that these decisions do not reflect discriminatory behavior toward certain groups or populations. More recently some work has been developed in traditional machine learning and deep learning that address such challenges in different subdomains. With the commercialization of these systems, researchers are becoming more aware of the biases that these applications can contain and are attempting to address them. In this survey, we investigated different real-world applications that have shown biases in various ways, and we listed different sources of biases that can affect AI applications. We then created a taxonomy for fairness definitions that machine learning researchers have defined to avoid the existing bias in AI systems. In addition to that, we examined different domains and subdomains in AI showing what researchers have observed with regard to unfair outcomes in the state-of-the-art methods and ways they have tried to address them. There are still many future directions and solutions that can be taken to mitigate the problem of bias in AI systems. We are hoping that this survey will motivate researchers to tackle these issues in the near future by observing existing work in their respective fields.


2021 ◽  
Vol 10 (2) ◽  
pp. 205846012199029
Author(s):  
Rani Ahmad

Background The scope and productivity of artificial intelligence applications in health science and medicine, particularly in medical imaging, are rapidly progressing, with relatively recent developments in big data and deep learning and increasingly powerful computer algorithms. Accordingly, there are a number of opportunities and challenges for the radiological community. Purpose To provide review on the challenges and barriers experienced in diagnostic radiology on the basis of the key clinical applications of machine learning techniques. Material and Methods Studies published in 2010–2019 were selected that report on the efficacy of machine learning models. A single contingency table was selected for each study to report the highest accuracy of radiology professionals and machine learning algorithms, and a meta-analysis of studies was conducted based on contingency tables. Results The specificity for all the deep learning models ranged from 39% to 100%, whereas sensitivity ranged from 85% to 100%. The pooled sensitivity and specificity were 89% and 85% for the deep learning algorithms for detecting abnormalities compared to 75% and 91% for radiology experts, respectively. The pooled specificity and sensitivity for comparison between radiology professionals and deep learning algorithms were 91% and 81% for deep learning models and 85% and 73% for radiology professionals (p < 0.000), respectively. The pooled sensitivity detection was 82% for health-care professionals and 83% for deep learning algorithms (p < 0.005). Conclusion Radiomic information extracted through machine learning programs form images that may not be discernible through visual examination, thus may improve the prognostic and diagnostic value of data sets.


2021 ◽  
Vol 23 (Supplement_6) ◽  
pp. vi139-vi139
Author(s):  
Jan Lost ◽  
Tej Verma ◽  
Niklas Tillmanns ◽  
W R Brim ◽  
Harry Subramanian ◽  
...  

Abstract PURPOSE Identifying molecular subtypes in gliomas has prognostic and therapeutic value, traditionally after invasive neurosurgical tumor resection or biopsy. Recent advances using artificial intelligence (AI) show promise in using pre-therapy imaging for predicting molecular subtype. We performed a systematic review of recent literature on AI methods used to predict molecular subtypes of gliomas. METHODS Literature review conforming to PRSIMA guidelines was performed for publications prior to February 2021 using 4 databases: Ovid Embase, Ovid MEDLINE, Cochrane trials (CENTRAL), and Web of Science core-collection. Keywords included: artificial intelligence, machine learning, deep learning, radiomics, magnetic resonance imaging, glioma, and glioblastoma. Non-machine learning and non-human studies were excluded. Screening was performed using Covidence software. Bias analysis was done using TRIPOD guidelines. RESULTS 11,727 abstracts were retrieved. After applying initial screening exclusion criteria, 1,135 full text reviews were performed, with 82 papers remaining for data extraction. 57% used retrospective single center hospital data, 31.6% used TCIA and BRATS, and 11.4% analyzed multicenter hospital data. An average of 146 patients (range 34-462 patients) were included. Algorithms predicting IDH status comprised 51.8% of studies, MGMT 18.1%, and 1p19q 6.0%. Machine learning methods were used in 71.4%, deep learning in 27.4%, and 1.2% directly compared both methods. The most common algorithm for machine learning were support vector machine (43.3%), and for deep learning convolutional neural network (68.4%). Mean prediction accuracy was 76.6%. CONCLUSION Machine learning is the predominant method for image-based prediction of glioma molecular subtypes. Major limitations include limited datasets (60.2% with under 150 patients) and thus limited generalizability of findings. We recommend using larger annotated datasets for AI network training and testing in order to create more robust AI algorithms, which will provide better prediction accuracy to real world clinical datasets and provide tools that can be translated to clinical practice.


Cancers ◽  
2021 ◽  
Vol 13 (19) ◽  
pp. 4740
Author(s):  
Fabiano Bini ◽  
Andrada Pica ◽  
Laura Azzimonti ◽  
Alessandro Giusti ◽  
Lorenzo Ruinelli ◽  
...  

Artificial intelligence (AI) uses mathematical algorithms to perform tasks that require human cognitive abilities. AI-based methodologies, e.g., machine learning and deep learning, as well as the recently developed research field of radiomics have noticeable potential to transform medical diagnostics. AI-based techniques applied to medical imaging allow to detect biological abnormalities, to diagnostic neoplasms or to predict the response to treatment. Nonetheless, the diagnostic accuracy of these methods is still a matter of debate. In this article, we first illustrate the key concepts and workflow characteristics of machine learning, deep learning and radiomics. We outline considerations regarding data input requirements, differences among these methodologies and their limitations. Subsequently, a concise overview is presented regarding the application of AI methods to the evaluation of thyroid images. We developed a critical discussion concerning limits and open challenges that should be addressed before the translation of AI techniques to the broad clinical use. Clarification of the pitfalls of AI-based techniques results crucial in order to ensure the optimal application for each patient.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Lara Lloret Iglesias ◽  
Pablo Sanz Bellón ◽  
Amaia Pérez del Barrio ◽  
Pablo Menéndez Fernández-Miranda ◽  
David Rodríguez González ◽  
...  

AbstractDeep learning is nowadays at the forefront of artificial intelligence. More precisely, the use of convolutional neural networks has drastically improved the learning capabilities of computer vision applications, being able to directly consider raw data without any prior feature extraction. Advanced methods in the machine learning field, such as adaptive momentum algorithms or dropout regularization, have dramatically improved the convolutional neural networks predicting ability, outperforming that of conventional fully connected neural networks. This work summarizes, in an intended didactic way, the main aspects of these cutting-edge techniques from a medical imaging perspective.


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