scholarly journals Clinical use of the III generation calcium antagonist Amlotopin the treatment of patients with cardiovascular disease

2013 ◽  
Vol 4 (4) ◽  
pp. 25-32
Author(s):  
V. S Zadionchenko ◽  
G. G Shehyan ◽  
A. A Yalymov

Despite the facts, revealing the mechanisms of pathogenesis and enhancing the effectiveness of the treatment of cardiovascular disease (CVD), the latter continues to be the leading cause of death and disability in the population. In this regard, the search for new treatments for CVD remains the most relevant in modern cardiology. In the treatment of CVD many classes of drugs are used, among which are calcium antagonists (AA). This class of drugs has been successfully used in the treatment of patients with arterial hypertension (AH) and coronary heart disease [1-3, 5].CA are a heterogeneous group of drugs that have the similar actionmechanism, but differ in a number of properties, including pharmacokinetics, tissue selectivity, effect on heart rate, etc. The main feature of all is the ability of CA to reversibly inhibit calcium current through the slow calcium channels. These funds are used in cardiology from the end of the 1960s and have since become so widely popular that in most developed countries they hold one of the first places on the prescription rate of drugs used for the treatment of cardiovascular disease. This is due, on the one hand, to the CA high clinical efficacy, and on the other to a relatively small number of contraindications to their purpose and the comparatively small number of side effects. [1, 2, 4, 5].

2009 ◽  
pp. 18-31
Author(s):  
G. Rapoport ◽  
A. Guerts

In the article the global crisis of 2008-2009 is considered as superposition of a few regional crises that occurred simultaneously but for different reasons. However, they have something in common: developed countries tend to maintain a strong level of social security without increasing the real production output. On the one hand, this policy has resulted in trade deficit and partial destruction of market mechanisms. On the other hand, it has clashed with the desire of several oil and gas exporting countries to receive an exclusive price for their energy resources.


Author(s):  
Valerii P. Trykov ◽  

The article examines the conceptual foundations and scientific, sociocultural and philosophical prerequisites of imagology, the field of interdisciplinary research in humanitaristics, the subject of which is the image of the “Other” (foreign country, people, culture, etc.). It is shown that the imagology appeared as a response to the crisis of comparatives of the mid-20th century, with a special role in the formation of its methodology played by the German comparatist scientist H. Dyserinck and his Aachen School. The article analyzes the influence on the formation of the imagology of post-structuralist and constructivist ideological-thematic complex (auto-reference of language, discursive history, construction of social reality, etc.), linguistic and cultural turn in the West in the 1960s. Shown is that, extrapolated to national issues, this set of ideas and approaches has led to a transition from the essentialist concept of the nation to the concept of a nation as an “imaginary community” or an intellectual construct. A fundamental difference in approaches to the study of an image of the “Other” in traditional comparativism and imagology, which arises from a different understanding of the nation, has been distinguished. It is concluded that the imagology studies the image of the “Other” primarily in its manipulative, socio-ideological function, i.e., as an important tool for the formation and transformation of national and cultural identity. The article identifies ideological, socio-political factors that prepared the birth of the imagology and ensured its development in western Humanities (fear of possible recurrences of extreme nationalism and fascism in post-war Europe, the EU project, which set the task of forming a pan-European identity). It is concluded that the imagology, on the one hand, has actualized an important field of scientific research — the study of the image of the “Other”, but, on the other hand, in the broader cultural and historical perspective, marked a departure not only from the traditions of comparativism and historical poetics, but also from the humanist tradition of the European culture, becoming part of a manipulative dominant strategy in the West. To the culture of “incorporation” into a “foreign word” in order to understand it, preserve it and to ensure a genuine dialogue of cultures, the imagology has contrasted the social engineering and the technology of active “designing” a new identity.


2019 ◽  
Vol 2 (1) ◽  
pp. 167-171
Author(s):  
Mohammad Sabiq ◽  
Akhmad Jayadi ◽  
Imam Nawawi ◽  
Mohammad Wasil

Materialism and sich are the driving spirit of the community in achieving economic and financial security that saves a holistic and socially just welfare. This can be seen from the lives of people in materialistic developed countries, where the level of social stress is higher, economic inequality widens, horizontal conflict is rife. This research uses Pierre Felix Bourdieu's social theory in seeing people trust the expenditure of material with other values, such as spiritual and cultural values ​​that are no less urgent as elements of social welfare development. This study found that materialism on the one hand has a positive effect, where people are encouraged to use material standards in measuring the level of welfare they expect. On the other hand, materialism closes the presence of values ​​such as spirituality, local wisdom and agriculture in completing more holistic welfare standards.


Author(s):  
Edward G. Goetz

This chapter describes the tension between integration and community development from the 1940s through the end of the 1960s. It describes the conflict within the African-American community between efforts to achieve integration on the one hand and building power and capacity within the community on the other. It describes the emergence and evolution of the fair housing movement in the U.S. Finally, the ways in which this conflict played out during the civil rights and Black Power eras is highlighted.


1973 ◽  
Vol 14 (2) ◽  
pp. 257-274 ◽  
Author(s):  
M. Tamarkin

From a close analysis of African activities and actions in the Kenyan town of Nakuru from the 19205 to the 1960s, it is argued that living in towns tended to consolidate the identities of tribal groups and to exacerbate their differences. Contrasts between the urban responses of the Kikuyu, on the one hand, and the Western Kenyan tribes, the Luo and the Abaluhya, on the other, are analysed, and are related to differences in the tribal structures and in the political, economic and social changes that were taking place in their rural areas. By the early 1960s, the stage was set for open political competition between tribal groups.


2004 ◽  
Vol 11 (3) ◽  
pp. 212-213 ◽  
Author(s):  
Stephen K Field

The recently published American Thoracic Society/European Respiratory Society statement distinguishes idiopathic pulmonary fibrosis (IPF), also known as usual interstitial pneumonia (UIP), from the other idiopathic interstitial pneumonias (IIPs) (1). Although the current classification of IIPs is different from the one developed by Liebow and Carrington (2) in the 1960s, the description of UIP has not changed, and it is still recognized as having distinctive clinical and pathological features that distinguish it from the other IIPs. IPF responds differently to systemic corticosteroid (steroid) therapy and has a different prognosis than the other IIPs, such as nonspecific interstitial pneumonitis, which previously were felt to be variants of the same condition (1,3,4). Despite therapy, most patients with IPF experience a progressive decline in pulmonary function, leading to respiratory failure and death, unless they undergo lung transplantation.


2015 ◽  
Vol 81 (3) ◽  
pp. 261-299 ◽  
Author(s):  
Michele Boldrin ◽  
Mariacristina De Nardi ◽  
Larry E. Jones

Abstract:The data show that an increase in government provided old-age pensions is strongly correlated with a reduction in fertility. What type of model is consistent with this finding? We explore this question using two models of fertility, the one by Barro and Becker (1989), and the one inspired by Caldwell and developed by Boldrin and Jones (2002). In the Barro and Becker model parents have children because they perceive their children’s lives as a continuation of their own. In the Boldrin and Jones’ framework parents procreate because the children care about their old parents’ utility, and thus provide them with old age transfers. The effect of increases in government provided pensions on fertility in the Barro and Becker model is very small, and inconsistent with the empirical findings. The effect on fertility in the Boldrin and Jones model is sizeable and accounts for between 55 and 65% of the observed Europe–US fertility differences both across countries and across time and over 80% of the observed variation seen in a broad cross section of countries. Another key factor affecting fertility the Boldrin and Jones model is the access to capital markets, which can account for the other half of the observed change in fertility in developed countries over the last 70 years.


Popular Music ◽  
2006 ◽  
Vol 26 (1) ◽  
pp. 65-81 ◽  
Author(s):  
ERIC W. ROTHENBUHLER

Robert Johnson (1911–1938) is the most venerated of all pre-war blues musicians; the veneration borders on hagiography. Recently published revisionist literature has constructed a sociologically realistic portrayal of a professional musician working among other musicians for a contemporary audience in a specific historical context. This has left unexplained, however, the veneration granted to his music by the audience for his records from the 1960s to today. This paper presents the case that these two bodies of fact can be connected and the one serve as an explanation for the other. As Robert Johnson learned his craft from records and radio, and polished his songs to be recorded, he effectively developed a ‘for-the-record’ aesthetic that made his music sound different to that of his Delta contemporaries and many others who used musical techniques honed in performance for an audience. Decades later, when a ‘for-the-record’ aesthetic was the taken-for-granted standard in popular musical culture, Robert Johnson's records sounded better than those of his contemporaries, and the audience from the 1960s to today has had a reason to think that he and his music were special.


2014 ◽  
Vol 23 (4) ◽  
pp. 589-614
Author(s):  
NIKOLAOS PAPADOGIANNIS

AbstractThis article examines the emotional standards and experiences connected with the entehno laiko music composed by Mikis Theodorakis that was immensely popular among left-wing Greek migrants, workers and students, living in West Germany in the 1960s and the early 1970s. Expanding on a body of literature that explores the transnational dimensions of protest movements in the 1960s and the 1970s, the article demonstrates that these transnational dimensions were not mutually exclusive with the fact that at least some of those protestors felt that they belonged to a particular nation. Drawing on the conceptual framework put forth by Barbara Rosenwein, it argues that the performance of these songs was conducive to the making of a (trans)national emotional community. On the one hand, for Greek left-wingers residing in West Germany and, after 1967, for Greek centrists too, the collective singing of music composed by Theodorakis initially served as a means of ‘overcoming fear’ and of forging committed militants who struggled for the social and political transformation of their country of origin. On the other, from the late 1960s onwards those migrants increasingly enacted this emotional community with local activists from West Germany as well.


1982 ◽  
Vol 16 (4) ◽  
pp. 265-278
Author(s):  
Bruce Boman

In a recent article appearing in this journal, a decision of the Administrative Appeals Tribunal granting a war pension for ischaemic heart disease arising out of the stresses of military service in World War II was severely criticised. The following is a literature review supporting the Tribunal's judgement by providing evidence for an association between both neurotic illness and stresses of varying severity on the one hand and cardiovascular disease on the other.


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