scholarly journals Possible effects of Ayurvedic herbs on management of COVID-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1219-1221
Author(s):  
Ajayratna Anandrao Meshram ◽  
Srihari S ◽  
Shweta Parwe
Keyword(s):  
Sore Throat ◽  
Virus Disease ◽  
Nasal Congestion ◽  
Scientific Evidence ◽  
Scientific Basis ◽  
Therapeutic Effects ◽  
Standard Formulation ◽  
Major Drawback ◽  
Runny Nose ◽  
Traditional Remedies

Corona virus disease COVID-19 is caused by coronavirus that can spread between animals and humans. The most common symptoms are fever, tiredness, and dry cough. Some individuals also develop aches and pains, nasal congestion, runny nose, sore throat, or diarrhoea. It was reported that traditional remedies may alleviate the symptoms of COVID-19. However, a major drawback is a lack of adequate scientific basis. Tulsi has multi-modal therapeutic effects, we hypothesize that Tulsi may be effective in the prevention and management of COVID-19. Though the existing literature supports the management of symptoms of COVID-19 using Tulsi, a lack of standard formulation limits its use. This is the need of time to start with translational research to provide scientific evidence for the efficacy and to establish the standard formulation of Tulsi in the management of COVID-19. Taking these things in to consideration efforts have been made to treat the patients of COVID-19 with Shaman Therapy Herbal Formulations. On the basis of findings and observations obtained after completion of current project it can be concluded that covid19 are progressive degenerative conditions in which Tridosha at its own Ashaya gets provoked and as it belongs to Madhyam Rogamarga treatment becomes challenging. This attempt possibly finds solutions which can prevent. Ayurveda the features like cough, running of nose & sore throat are caused due to Dushti (vitiation) of Pranavaha Srotas & also having Annavaha Strotas Dushti & Rasavaha Strotas Dushti. Ayurveda is the world’s oldest medical system that can manage any disease without side effects.

Ayurveda’s Holistic Lifestyle Approach for the Management of Coronavirus disease (COVID-19): Possible Role of Tulsi

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 16-18
Author(s):  
Sai Sailesh Kumar Goothy ◽  
Srilatha Goothy ◽  
Anita Choudhary ◽  
Potey G G ◽  
Hirok Chakraborty ◽  
...  
Keyword(s):  
Nasal Congestion ◽  
Scientific Evidence ◽  
Scientific Basis ◽  
Treatment Modalities ◽  
Therapeutic Effects ◽  
Standard Formulation ◽  
Major Drawback ◽  
Runny Nose ◽  
Corona Virus ◽  
Traditional Remedies

Coronavirus disease COVID-19 is caused by the recently discovered corona virus that can spread between animals and humans. The outbreak of the corona virus was begun in Wuhan, China, in December 2019. The most common symptoms are fever, tiredness, and dry cough. Some individuals also develop aches and pains, nasal congestion, runny nose, sore throat, or diarrhea. It was reported that traditional remedies may alleviate the symptoms of COVID-19. Ayurveda is the world's oldest medical system that can manage any disease without side effects. Ayurveda is equipped with varieties of treatment modalities to handle with any type of deadly diseases. However, a major drawback is a lack of adequate scientific basis. Tulsi has multi-modal therapeutic effects, we hypothesize that tulsi may be effective in the prevention and management of COVID-19. Though the existing literature supports the management of symptoms of COVID-19 using tulsi, a lack of standard formulation limits its use. This is the need of time to start with translational research to provide scientific evidence for the efficacy and to establish the standard formulation of tulsi in the management of COVID-19.

scholarly journals ROLE OF AYURVEDA AND YOGA FOR COVID-19

2020 ◽  
Vol 8 (8) ◽  
pp. 4211-4215
Author(s):  
Priyanka V ◽  
Yogesh Jakhar ◽  
Anupam Pathak
Keyword(s):  
Immune System ◽  
Virus Disease ◽  
Nasal Congestion ◽  
Antiviral Treatment ◽  
Medical Science ◽  
Scientific Basis ◽  
World Health ◽  
Treatment Modalities ◽  
Major Drawback ◽  
Corona Virus

The outbreak of Corona virus disease (COVID-19) has been recently declared as Public Health Emergency of International Concern (PHEIC) by World Health Organization and the virus has now spread beyond the boundaries of countries and continents. At present, no specific antiviral treatment or vaccine is available or recommended to counter the COVID-19, and the potential therapy is still symptomatic. The outbreak of the Corona virus was begun in Wuhan, China in December 2019. The most common symptoms are fever, tiredness and dry cough. Some individuals also develop aches and pains, nasal congestion, runny nose, sore throat, or diarrhea. It was reported that traditional remedies may alleviate the symptoms of COVID19. Ayurveda is the world’s oldest medical system that can manage any disease without side effects. Ayurveda is equipped with varieties of treatment modalities to handle with any type of deadly diseases. However, a major drawback is a lack of adequate scientific basis. In recent time, a branch of modern medical science has developed and is known as Psycho- Neuro -Immunology. It deals with the phenomenon of how our thoughts and emotions can affect our immune system. Stress, fear and negative emotions are known to weaken our immune system while Yoga (including meditation), mindfulness, positive emotions, and relaxa-tion strengthen it. Yoga plays an important role to strengthen our immune system.

scholarly journals The natural history of community-acquired common colds symptoms assessed over 4-years

2015 ◽  
Vol 53 (1) ◽  
pp. 81-88
Author(s):  
Theodore J. Witek ◽  
David L. Ramsey ◽  
Andrew N. Carr ◽  
Donald K. Riker
Keyword(s):  
Sore Throat ◽  
Common Cold ◽  
Nasal Congestion ◽  
Runny Nose ◽  
Symptom Evaluation ◽  
Symptom Frequency ◽  
Bothersome Symptom ◽  
History Of ◽  
The Common ◽  
Pain Symptoms

Background: The common cold is the most frequently experienced infection among humans, but limited data exist to characterize the onset, duration, severity and intersection of symptoms in community-acquired colds. A more complete understanding of the symptom frequency and burden in naturally occurring colds is needed. Methodology: We characterized common cold symptoms from 226 cold episodes experienced by 104 male or female subjects. Subjects were enrolled in the work environment in an attempt to start symptom evaluation (frequency and severity) at the earliest sign of their cold. We also assessed the symptom that had the greatest impact on the subject by asking them to identify their single most bothersome symptom. Results: Symptom reporting started within 24 hours of cold onset for most subjects. Sore throat was a harbinger of the illness but was accompanied by multiple symptoms, including nasal congestion, runny nose and headache. Cough was not usually the most frequent symptom, but was present throughout the cold, becoming most bothersome later in the cold. Nasal congestion, pain (eg, sore throat, headache, muscle pains) or feverishness and secretory symptoms (eg, runny nose, sneezing), and even cough, were simultaneously experienced with high incidence over the first 4 days of illness. The single most bothersome symptom was sore throat on day 1, followed by nasal congestion on days 2-5 and cough on days 6 and 7. Conclusion: There is substantial overlap in the appearance of common cold symptoms over the first several days of the common cold. Nasal congestion, secretory and pain symptoms frequently occur together, with cough being somewhat less prominent, but quite bothersome when present. These data establish the typical symptomatology of a common cold and provide a foundation for the rational treatment of cold symptoms typically experienced by cold sufferers.

scholarly journals Preparing for COVID-19: The lessons from SARS 2003 in Canada

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
David White
Keyword(s):  
Infectious Disease ◽  
Older People ◽  
Sore Throat ◽  
Nasal Congestion ◽  
Medical Attention ◽  
Special Treatment ◽  
Medical Problems ◽  
Runny Nose ◽  
Difficulty Breathing ◽  
Seriously Ill

What is Covid-19? Definition: COVID-19 is the infectious disease caused by the most recently discovered coronavirus. It was first recognized in Wuhan, China, in December 2019. Symptoms: The most common symptoms are fever, tiredness, and dry cough. Some people may have aches and pains, nasal congestion, runny nose, sore throat or diarrhea. Course: Symptoms usually begin gradually. Some people become infected but don’t develop any symptoms. Most people (about 80%) recover from the disease without needing special treatment. Around 1 out of every 6 people becomes seriously ill and develops difficulty breathing. At risk: Older people, and those with underlying medical problems. People with fever, cough and difficulty breathing should seek medical attention.

scholarly journals Boi-ogi-to (TJ-20), a Kampo Formula, Suppresses the Inflammatory Bone Destruction and the Expression of Cytokines in the Synovia of Ankle Joints of Adjuvant Arthritic Rats

2017 ◽  
Vol 2017 ◽  
pp. 1-10 ◽  
Author(s):  
Xinwen Zhang ◽  
Zhou Wu ◽  
Yicong Liu ◽  
Junjun Ni ◽  
Chunfu Deng ◽  
...  
Keyword(s):  
Scientific Evidence ◽  
Bone Destruction ◽  
Scientific Basis ◽  
Helper T Cells ◽  
Therapeutic Effects ◽  
Main Function ◽  
Dependent Manner ◽  
Ankle Joints ◽  
Anti Inflammatory ◽  
Inflammatory Effect

TJ-20 is a formula consisting of 6 herbs that has been used in the clinical treatment of rheumatoid arthritis (RA) in China and Japan for centuries. However, scientific evidence of the effects of TJ-20 has not been established. In the present study, we focused on the therapeutic effects and investigated the main function of TJ-20 on adjuvant arthritis (AA), an animal model of RA, which was induced with complete Freund’s adjuvant (CFA). TJ-20 was administered orally at 600 mg/kg once a day from 0, 7, and 10 days to 8 weeks after the CFA treatment. TJ-20 significantly ameliorated inflammatory progression and bone destruction in AA in a time-dependent manner. Furthermore, TJ-20 significantly reduced the increased changes in a number of macrophages and helper T cells. Moreover, TJ-20 suppressed the expression of TNF-αwhereas it augmented the expression of IL-10 and attenuated Th1 cells responses in the synovia of the ankle joint. Therefore, TJ-20 regulated the expression of proinflammatory and anti-inflammatory cytokines in macrophages and Th1/Th2 balance in the synovia of ankle joints in AA rats. These results suggest the positive anti-inflammatory effect of TJ-20 and provide a scientific basis for the clinical use of TJ-20 for RA.

COVID-19: The Unprecedented Malady-A Holistic Review

Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Viney Chawla ◽  
Pooja A Chawla
Keyword(s):  
Virus Disease ◽  
Drug Repurposing ◽  
Signs And Symptoms ◽  
Effective Vaccine ◽  
Runny Nose ◽  
Difficult Time ◽  
Holistic Review ◽  
The World ◽  
Spanish Flu ◽  
Corona Viruses

Background: Corona virus disease (COVID-19) is spreading rapidly at an unprecedented scale across continents and has emerged as the single biggest risk the world has faced in modern times. Some scientists are comparing it to Spanish flu that created havoc around a century ago. The fear of death by COVID-19 looms large at the world today. The disease has reached devastating proportions since its first reports in December 2019. Doctors are having a difficult time dealing with this challenge and the microbiologists are having sleepless nights to bring about an effective vaccine for this disease. Methods: A number of research and review articles have been exhaustively reviewed. The collected data was meticulously analysed and documented. Conclusion: This paper reviews the different types of corona viruses, the structure of SARS-CoV-2 responsible for COVID19, its transmission, virulence. Further, the article discusses the diagnosis, signs and symptoms like fever, breathlessness, cough, potential loss of taste or smell, sneezing, runny nose, fatigue, headache, sore throat and different treatment approaches including drug repurposing being tried by doctors around the globe that may come handy in the management of disease symptoms. The article describes the use of remdesivir, ribavarin, lopinavir, favipiravir, hydoxychloroquine, chloroquine, tocilizumab among others in treating COVID-19.

Scientific basis of the System for Analysis of Validity in Evaluation: The SAVE Metaprotocol.

2021 ◽  
Vol 2 (2) ◽  
pp. 3679-3684
Author(s):  
Antonio Domínguez-Muñoz
Keyword(s):  
Disability Pension ◽  
Scientific Evidence ◽  
Daily Practice ◽  
Scientific Basis ◽  
Third Party ◽  
Significant Advance ◽  
Fraud Triangle ◽  
Clinical Context ◽  
Academic Knowledge ◽  
Flexible Application

There are multiple situations, often related to the administrative or judicial field, in which it is necessary to use a healthy skepticism, to question the validity of an assertion, appealing to the evidence that can prove or disprove it. (Shermer, 2008). From a child custody issue to facing a harsh criminal conviction, to applying for a disability pension or obtaining an indemnity in an insurance context; in all of them, there is the opportunity to use deception for one's own benefit, harming a third party, through fraud. As we know, opportunity, together with prior motivation or incentive and subsequent justification, constitute the classic fraud triangle proposed by Cressey (1961).             This questioning of the validity of the case understood as its accuracy or correspondence with what it pretends to be and independently of its various types, is only possible from a method of analysis based on scientific evidence that benefits from using a system ordered by rules for the investigation - which we know as a protocol (Amezcua, 2000) - as well as a multiple approaches (Campbell and Fiske, 1959) that is proportionate to a conception of the detection and demonstration of deception from the approach of complexity (Cardozo, 2011). If, in addition, such a system was sufficiently flexible to be useful in the daily practice of the various fields in which it may be necessary to use it, it could represent a significant advance in this area.             These, together with those of Behavior Analysis in Ethology, Criminology, and Psychology, are the initial theoretical bases on which the System of Analysis of Validity in Evaluation (SAVE) is designed, establishing four phases in two domains of multiple and orderly but flexible application, to scientifically question the validity of a case and provide it with consistency and even legal value when appropriate. Although SAVE was born in a clinical context (Domínguez-Muñoz et al., 2014) its main area of knowledge is the study of lying and deception, an area in which there is a large bibliography, somewhat dispersed among various disciplines, which must be incorporated as a source of academic knowledge for its use in the applied field (Domínguez-Muñoz et al., 2017).    

Comparative study between oral acetaminophen and lidocaine spray on endotracheal tube-related sore throat in adult intensive care

2021 ◽  
Keyword(s):  
Intensive Care ◽  
Pain Management ◽  
Endotracheal Tube ◽  
Sore Throat ◽  
Common Source ◽  
Therapeutic Effects ◽  
Throat Pain ◽  
High Satisfaction ◽  
Before And After ◽  
Lidocaine Spray

ackground/Purpose: Endotracheal tube (ETT)-related sore throat is a common source of stress in intensive care. Quantitative studies on therapy for ETT-related sore throat remain limited. The current study evaluated the therapeutic effects of oral acetaminophen (ACT) and lidocaine (LIDO) spray on pain relief for ETT-related sore throat in intensive care. Methods: Patients who could communicate with caregivers non-verbally and who had acquired ETT-related sore throat at a medical intensive care unit (ICU) were enrolled. The medications were dispensed at the request of the patients. The intensity of ETT-related throat pain was recorded for quantitative comparison before and after patients received 500 mg of ACT orally or one dose of 10% LIDO spray locally. Before leaving the ICU, the patients were interviewed by a research nurse to assess the effect of these interventions on satisfaction with pain management for ETT-related sore throat. Results: We enrolled 89 patients during the study period, and the intensity of ETT-related throat pain significantly decreased after treatment (6.97 in 5 min before vs. 3.60 in 120 min after oral ACT, P < 0.001; 8.56 in 5 min before vs. 4.12 in 120 min after LIDO application, P < 0.001). The degree of pain reduction over time differed between the ACT and LIDO groups. Patients in the LIDO group made more requests for additional therapy compared with patients in the ACT group (1 LIDO spray per request for an average of 4.7 requests vs. 1 ACT dose per request for an average of 1.3 requests, P < 0.001). Patients in both the ACT and LIDO groups reported high satisfaction with pain management for ETT-related sore throat (87.3 of 100 vs. 86.5 of 100, respectively, P = 0.805). Conclusion: ACT and LIDO treatment can effectively attenuate ETT-related sore throat. Patients were highly satisfied with pain management for ETT-related sore throat after both oral ACT and local LIDO application.

scholarly journals Limosilactobacillus reuteri ATCC PTA 5289 and DSM 17938 as adjuvants to improve evolution of pharyngitis/tonsillitis in children: randomised controlled trial

2021 ◽  
Vol 12 (2) ◽  
pp. 137-145
Author(s):  
A. Maya-Barrios ◽  
K. Lira-Hernandez ◽  
I. Jiménez-Escobar ◽  
L. Hernández ◽  
A. Ortiz-Hernandez ◽  
...  
Keyword(s):  
Randomised Controlled Trial ◽  
Respiratory Infections ◽  
Nasal Congestion ◽  
Controlled Trial ◽  
Immunoglobulin A ◽  
Published Data ◽  
Necrosis Factor Alpha ◽  
Runny Nose ◽  
Probiotic Product ◽  
Randomised Controlled

Pharyngitis and tonsillitis are the most common acute respiratory infections (ARIs) in children aged ≤5 years. The analysis of published data showed that some probiotics could decrease the frequency and number of days with ARIs. This study evaluated the safety and efficacy of Limosilactobacillus reuteri ATCC PTA 5289 and DSM 17938 to reduce the duration and severity of ARI symptoms. This randomised controlled trial included children aged from 6 months to 5 years, with pharyngitis or tonsillitis, who were randomised to receive a probiotic product containing L. reuteri ATCC PTA 5289 and L. reuteri DSM 17938 or placebo, as drops, ingested orally for 10 days as adjuvants to the use of non-steroidal anti-inflammatory drugs. The main outcomes were the duration and severity of ARI symptoms. The secondary outcomes were changes in salivary immunoglobulin A and inflammatory biomarkers. There was no fever on day 2 and subsequent days in the L. reuteri group (37.3 ±0.5 °C vs 38.6±0.3 °C, P<0.05). Beginning on day 3, the severity of sore throat (5±0.9 vs 8±1.2, P<0.05) was lower in the L. reuteri group. Significant differences in the days with runny nose, nasal congestion, days of non-programmed visits to the medical office or emergency department, levels in tumoral necrosis factor-alpha (TNF-alpha) and related costs of treatment were observed in the L. reuteri group. The frequency of adverse events was similar between the groups. Therefore, L. reuteri ATCC PTA 5289 combined with L. reuteri DSM 17938 is a safe and effective adjunct to reduce the symptoms of pharyngitis or tonsillitis in children.

scholarly journals Symptomatic manifestations of the disease caused by coronavirus (COVID-19) in adults: systematic review

2021 ◽  
Vol 42 (spe) ◽  
Author(s):  
Antonio Rosa de Sousa Neto ◽  
Ana Raquel Batista de Carvalho ◽  
Erika Morganna Neves de Oliveira ◽  
Rosilane de Lima Brito Magalhães ◽  
Maria Eliete Batista Moura ◽  
...  
Keyword(s):  
Systematic Review ◽  
Abdominal Pain ◽  
Chest Pain ◽  
Web Of Science ◽  
Scientific Literature ◽  
Nasal Congestion ◽  
Research Question ◽  
Clinical Manifestations ◽  
Runny Nose ◽  
Cough Headache

ABSTRACT Objective To identify symptoms of COVID-19 in adults in the scientific literature. Method Systematic review of studies published from December 1, 2019 to April 21, 2020 from the Scopus, Web of Science and PubMed databases, in order to answer the following research question: “What are the symptoms caused by COVID-19 in adults?” using the keywords “Symptoms”, “Clinical Manifestations”, “Coronavirus”, “COVID-19”. Results Of the total 105 references, 13 references that addressed the symptoms of COVID-19 were selected. Fever and normal or dry cough were symptoms present in all studies. Conclusion The symptoms identified in adult patients were fever, normal or dry cough, headache, pharyngalgia, dyspnea, diarrhea, myalgia, vomiting, sputum or expectoration, anxiety or chest pain, fatigue, nausea, anorexia, abdominal pain, rhinorrhea, runny nose or nasal congestion, dizziness, chills, systemic pain, mental confusion, hemoptysis, asthma, taste disorder, smell disorder, belching and tachycardia.

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