scholarly journals A review of the phytochemical compounds and pharmacological activities of Eurycoma longifolia

2021 ◽  
Vol 12 (2) ◽  
pp. 1462-1470
Author(s):  
Insanu M ◽  
Pratiwi S N E ◽  
Fidrianny I
Keyword(s):  
Bitter Taste ◽  
Scientific Work ◽  
Digital Object Identifier ◽  
Health Food ◽  
High Demand ◽  
Pharmacological Activities ◽  
Eurycoma Longifolia ◽  
Tall Tree ◽  
Food Market ◽  
Phytochemical Compounds

Eurycoma longifolia belongs to Simaroubaceae family. It is a tall tree and has different local name from many countries and this review consisted of their traditional usage, phytochemical compounds and pharmacological activity. A systematic review was conducted to study the scientific work of E. longifolia which published in the last 10 years and minimum 20 articles that published in the last 2 years, published in Pubmed, Scopus etc. also has a digital object identifier (DOI). E. longifolia was a popular traditional medicine. The leaves wasused as supplement for giving birth, its bark as anthelmintic and its roots as antimalaria, laxative, antidiabetic etc.Due to high demand of this plant there are various formula of E. longifolia available in health food market. Many studies have been performed to determine the active constituents and pharmacology activities of E. longifolia.  Alkaloid, quassinoid, polyphenols, flavonoid, polysaccharide, triterpenoid were found in E. longifolia.  Quassinoids is a major phytochemical compound in E. longifolia which has various types like eurycumanone, eurycomanol, eurycomadilactone and eurylactone. Quassinoids has bitter taste and often found in Simaroubaceae family.Pharmacological activities of E. longifolia such as anti-inflammatory, analgesic, antioxidant, antimicrobial, antidiabetic, anti-osteoporotic activities. The literature review results showed that E. longifolia can be considered as medicinal plant for human. In the future, further studies on mechanism of pharmacology activity of E. longifolia are warranted.

scholarly journals Overview of Phytochemical Compounds and Pharmacological Activities of Ananas Comosus L. Merr

2020 ◽  
Vol 11 (3) ◽  
pp. 4760-4766
Author(s):  
Hartati R ◽  
Suarantika F ◽  
Fidrianny I
Keyword(s):  
Traditional Medicine ◽  
Biological Activities ◽  
Scientific Work ◽  
Ananas Comosus ◽  
Pharmacological Activities ◽  
Phytochemical Compounds ◽  
Anti Inflammatory ◽  
Vitro Analysis

Ananas comosus L. Merr, known as pineapple, belongs to the Bromeliaceae family. This plant has been used as traditional medicine and continues until now in conventional herbal medicine. The pineapple was distributed in some countries such as China, India, Indonesia, Malaysia, Thailand and originated from South America. This article delved the scientific work about Ananas comosus focussing their usage as traditional medicine, chemical compounds and biological activities. All of the pieces of information were obtained from the scientific literature such as Science Direct, Google Scholar, Scopus and PubMed. Based on the literature survey,different parts of pineapple (Ananas comosus) are used in traditional medicine, used asan anti-inflammatory agent,anti-oedema, digestive disorder, antimicrobial, vermicide, and purgative. Phytochemical compounds from A. comosus have been provided, including ascorbic acid, quercetin, flavones-3-ol, flavones, and ferulic acid. The crude extracts of A. comosus have many pharmacological activities such as anti-fungal, anti-inflammatory, antioxidant, antibacterial. This discovery becomes possible due to scientific isolation and in vivo or in vitro analysis of A.comosus.

scholarly journals A review of the phytochemical compounds and pharmacological activities from selected Ficus plants

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 921-928
Author(s):  
Insanu M ◽  
Santoso F R C ◽  
Fidrianny I
Keyword(s):  
Scientific Work ◽  
Review Of The Literature ◽  
Steroid Saponin ◽  
Pharmacological Activities ◽  
Wide Range ◽  
Ficus Virens ◽  
Pure Compounds ◽  
Phytochemical Compounds ◽  
Ficus Hirta ◽  
Ficus Lyrata

The Ficus genus belongs to the Moraceae family were used for medicinal purposes. Distributed in America, Asia, Africa, and Australia, there were sixteen species accepted in Indonesia. They were Ficus callosa, Ficus melinocarpa, Ficus elastica, Ficus drupaceae, Ficus geocarpa, Ficus Superba, Ficus heteropoda, Ficus fistulosa, Ficus hirta, Ficus ampelas, Ficus adenosperma, Ficus ardisioides, Ficus consociate, Ficus ribes, Ficus lyrata, Ficus virens Aiton. This article reviewed the scientific work of the Ficus genus. Their traditional usage, phytochemical compounds, and pharmacological activity were summarized. This study aims at providing a collection of publications on selected species of Ficus genus. A critical review of the literature data revealed secondary metabolite like triterpenoid, steroid, saponin, flavonoid, phenolic compound and alkaloid were found in some species of Ficus. Some pure compounds such as quercetin,  quercetin 3-O-α-L-arabinopyranoside, epilupeol acetate, oleanolic acid, friedelin, elastiquinone,  pinocembrin-7-O-β-D-glucoside, and ficusoside B were isolated. A wide range of pharmacological activities was observed. Antimicrobial, antioxidant, antiviral, antiparasitic, cytotoxic, and antimalarial were found in previous researches. Ficus genus was potential to be developed as a medicinal plant.

scholarly journals Pyrostegia Genus: An Update Review of Phytochemical Compounds and Pharmacological Activities

2020 ◽  
Vol 11 (3) ◽  
pp. 10664-10678
Keyword(s):  
Scientific Literature ◽  
Chemical Constituents ◽  
Sickness Behavior ◽  
Scientific Work ◽  
Phenylethanoid Glycosides ◽  
Pharmacological Activities ◽  
Traditional Medicines ◽  
Traditional Uses ◽  
Phytochemical Compounds ◽  
Genotoxicity Tests

The Pyrostegia genus of the Bignoniaceae family. This genus is consists of four species and indigenous to South America. The plants of this genus are being applied in traditional uses in Brazil. This review of the scientific work about Pyrostegia genus was highlighting and updating their traditional uses, phytochemical compounds, pharmacological activities, genotoxicity tests, and toxicity studies. The information was systematical with the scientific literature database, including Elsevier, Google Scholar, PubMed, Science Direct, and Scopus, and Springer. The literature survey showed various traditional uses of Pyrostegia genus, such as drugs to therapy diarrhea, coughing, vitiligo, jaundice, and respiratory system-related diseases, i.e., colds, coughs, and bronchitis. Phytochemical compounds from the Pyrostegia genus have shown the presence of flavonoids, phenolic compounds, phenylpropanoids, phenylethanoid glycosides, triterpenes, and sterols. The extract of Pyrostegia genus has a variety of pharmacology actions, i.e., antioxidant, antimicrobial, antifungal, anti-inflammatory, wound healing activities, antinociceptive, analgesic, vasorelaxant activities, antitumor, cytotoxic, hepatoprotective, antitussive, anthelmintic, hyperpigmented, treatment of sickness behavior, estrogenic, antihypertensive, and immunomodulatory. Pyrostegia genus is considerably used in traditional medicines and has various pharmacological activities. However, most species of Pyrostegia genus must be further researched concerning its chemical constituents and pharmacological activities.

scholarly journals Open Innovation and Business Model of Health Food Industry in Asia

2021 ◽  
Vol 7 (3) ◽  
pp. 174
Author(s):  
Nathapornpan Piyaareekul Uttama
Keyword(s):  
Food Consumption ◽  
Digital Technology ◽  
Open Innovation ◽  
Fixed Effects ◽  
Market Development ◽  
Health And Wellness ◽  
Health Food ◽  
Health Trends ◽  
Panel Quantile Regression ◽  
Food Market

Health trends and digital technologies are of great significance for the health and wellness food market and its development in the future. This study examines whether health trends, digital technology, and market concentration influence health and wellness food consumption in the Asian market. Our analysis uses a panel dataset covering 14 Asian economies from the period 2006–2020 and a panel quantile regression technique with non-additive fixed effects. The results reveal that health trends and digital technology have positive and significant impacts on health and wellness food consumption, whereas the concentration of distribution channels has a negative and significant impact. These results also offer insights into each type of health and wellness food consumption, thereby contributing to the health and wellness food market development. Finally, this study suggests the health and wellness food business development through a consumer-driven open innovation strategy.

scholarly journals ETHNOBOTANICAL, PHYTOCHEMICAL, AND PHARMACOLOGICAL PROPERTIES OF NEPENTHES SPECIES: A REVIEW

2017 ◽  
Vol 10 (11) ◽  
pp. 16 ◽  
Author(s):  
Shuaibu Babaji Sanusi ◽  
Mohd Fadzelly Abu Bakar ◽  
Maryati Mohamed ◽  
Siti Fatimah Sabran ◽  
Muhammad Murtala Mainasara
Keyword(s):  
Folk Medicine ◽  
Therapeutic Agents ◽  
Bioactive Components ◽  
Pharmacological Activities ◽  
Crude Extracts ◽  
Gastrointestinal Discomfort ◽  
Wide Range ◽  
Long Time ◽  
Phytochemical Compounds ◽  
Ethnobotanical Uses

The genus Nepenthes (Nepenthaceae) has been utilized in folk medicine for a long time in India and Southeast Asia countries. They are used in the treatment of leprosy, cholera, night blindness, gastrointestinal discomfort, dysentery, stomachache, and bed-wetting among others. This review highlights the ethnobotanical uses, phytochemicals, and pharmacological activities of both crude extracts and pure bioactive compounds of Nepenthes spp. The phytochemical compounds isolated from Nepenthes species include flavonoids, terpenoids, tannins, alkaloids, and steroids among other phytochemicals. A wide range of pharmacological activities was exhibited by the crude extracts and pure bioactive components such as antibacterial, antifungal, antimalarial antioxidant, antidiabetic, antiosteoporotic, anti-inflammatory, cytotoxicity, and hypolipidemic activities. This review revealed that many active compounds are present in Nepenthes spp. However, many pharmacological screenings such as anticancer, antiviral, wound healing, antihelminthic, antidiarrheal properties, among others have not been carried out yet. Therefore, more biological investigations and phytochemical screenings are required to fully explore the genus Nepenthes which may lead to development of new therapeutic agents.  

scholarly journals Capsule Formulation of Ethanolic Extract of Pasak Bumi (Eurycoma Longifolia Jack.,) and its Effect on Human Health Vital Signs

2017 ◽  
Vol 22 (2) ◽  
pp. 91
Author(s):  
Laela Hayu Nurani ◽  
Eka Kumalasari ◽  
Abdul Rohman ◽  
Sitarina Widyarini
Keyword(s):  
Bitter Taste ◽  
Vital Signs ◽  
Ethanolic Extract ◽  
Ethanol Extract ◽  
Inclusion Criteria ◽  
Capsule Formulation ◽  
Healthy Human ◽  
Eurycoma Longifolia ◽  
Healthy Humans ◽  
Eurycoma Longifolia Jack

Pasak bumi (Eurycoma longifolia) has the potential to be developed as antihypertensive, antipyretic, aphrodisiacs and health supplements. The use of E. longifolia as a traditional medicine needs to be pursued in the form of more effective and appropriate formulation. The capsule preparations are easy to make and cancover the bitter taste of E. longifolia. Clinical trials in this study use design pre-post treatment in healthy humans. Subjects used were male - healthy men and healthy women who met inclusion criteria and were subjected with formulated capsule for 14 days. The study resulted capsule formula comprising of the ethanolic extract of E. longifolia 300 mg, vivapur 101 300 mg, 58 mg maydis starch, aerosil 3%, talc 2%, and Mg stearate 1%. The results showed that the capsule of E. longifolia did not affect the value of heart rate, respiration rate, body temperature and weight (P > 0.05), based on paired t-test, but they causes a decrease in blood pressure of healthy human. The ethanol extract of E. longifolia caused vasodilation of blood vessels that can be used in antihypertensive therapy.

scholarly journals Review Based Upon Ayurvedic and Traditional Uses of Cinnamomum tamala (Tejpatta)

2021 ◽  
Vol 68 (2) ◽  
Author(s):  
Shifali Thakur ◽  
Gitika Chaudhary
Keyword(s):  
Chemical Constituents ◽  
Bioactive Constituents ◽  
Pharmacological Activities ◽  
The Past ◽  
Cinnamomum Tamala ◽  
Medicinal Use ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents ◽  
Herbal Plant ◽  
Flavoring Agent

Cinnamomum tamala is an evergreen plant native to Sri Lanka and India. This herbal plant is commonly called Indian cassia, Tejpatta and Indian bay leaf. There are many bioactive constituents isolated from plant Cinnamomum tamala. Leaves of the plant possess aromatic fragrance and are also utilized as a flavoring agent. It is used in food curry, pickles and other spices. Besides food application, the leaves have also been used for curing a number of ailments. All parts of the plant possess many major bioactive chemical constituents like cinnamaldehyde, trans-cinnamaldehyde, 3,4,5,7- tetrahydroxyflavone, 3,3,4,5,6- pentahydroflavone (non-glycoside compounds), kaempferol, eugenol, etc. These phytochemical compounds have many pharmacological activities such as anticancer, antidiabetic, antimicrobial, hepatoprotective, antidiarrheal and immunomodulatory. In the past time, it is also considered for medicinal use. Their medicinal use was also mentioned in the literature of ayurveda, yunani and other traditional systems of medicine. Due to aromatic fragrance, it is also utilized in the perfume industry. The major aim of this review is to give a brief knowledge about the plant Cinnamomum tamala based on their phytochemical constituents, ayurvedic view, folk view and pharmacological application.

scholarly journals Soil Quality in the Poganis, Ramnei and Doclin Hills Measures of improvment

2019 ◽  
Vol 70 (7) ◽  
pp. 2463-2470
Author(s):  
Lucian Nita ◽  
Dorin Tarau ◽  
Simona Nita ◽  
Alina Heghes ◽  
Radu Bertici ◽  
...  
Keyword(s):  
Agricultural Land ◽  
Soil Formation ◽  
Terrestrial Ecosystems ◽  
Scientific Work ◽  
Basic Information ◽  
High Demand ◽  
Soil Resources ◽  
Genetic Types ◽  
Improvement Measures ◽  
Formation And Evolution

The purpose of current research is part of the current scientific work and practice regarding the accumulation of knowledge on the structure and characteristics of the edaphic envelope and its quality in order to establish measures for its improvement. The researched issue covers an area of 113940 ha (of which 77039 ha, 67.61% are agricultural land), located in the Poganis, Ramnei and Doclin hills, namely Barzavei Plain. The paper provides basic information and methodological elements regarding the classification and evaluation of soil resources, thus integrating itself in the broader field of complex studies of natural resources and their valorisation thus assuring the environmental protection. This research takes place at a time when there is a high demand of education in soil-related issues from its perspective as a basis for the existence of human communities, component and support of terrestrial ecosystems. From this perspective, the physico-geographic conditions of soil formation and evolution are briefly, but succinctly presented, mentioning the way in which the particularities of the area within the space taken into consideration, of only 113940 ha as a stretch, determine a great diversity of ecological conditions. They are generated by the variability of the factors (cosmic-atmospheric and telluric-edaphic), for which the main processes of formation and evolution have achieved a different development and intensity, the result of which are different genetic types of soils (related or totally different) in constant evolution and demanding specific improvement measures.

scholarly journals A Network Pharmacology-Based Study on Pharmacological Activities and Mechanisms of Essential Oil in Leaves of C. Grandis ‘Tomentosa’

2021 ◽  
Author(s):  
Jieshu You ◽  
Sheng-cai He ◽  
Liang Chen ◽  
Zhen-hui Guo ◽  
Fei Gao ◽  
...  
Keyword(s):  
Essential Oil ◽  
Function Analysis ◽  
Network Pharmacology ◽  
Chemical Components ◽  
Pathway Enrichment Analysis ◽  
Health Food ◽  
Disease Network ◽  
Pharmacological Activities ◽  
Integrated Network ◽  
Target Disease

Abstract Background and Objective: Citrus grandis ‘Tomentosa’, as the fruit epicarp of C. grandis ‘Tomentosa’ or C. grandis (L.) Osbeck, is widely used in health food and medicine. Actually, based on our survey results, there are also rich essential oils with bioativities in leaves, but the chemical compounds in this part and relevant pharmacological activities have never been studied systematically yet. Therefore, this study was to preliminarily decipher the pharmacological activities and mechanisms of the essential oil in leaves of C. grandis ‘Tomentosa’ by an integrated network pharmacology approach. Methods: Essential oil compositions from leaves of C. grandis ‘Tomentosa’ were identified using GC-MS/MS. And then the targets of these oil compositions were predicted and screened from TCMSP, SwissTargetPrediction, STITCH and SEA databases. STRING database was used to construct the protein-protein interaction networks, and the eligible protein targets were input into WebGestalt 2019 to carry out GO enrichment and KEGG pathway enrichment analysis. Based on the potential targets, disease enrichment information was obtained by TTD databases. Cytoscape software was used to construct the component-target-disease network diagrams. Results: Finally, 61 essential oil chemical components were identified by GC-MS/MS, which correspond to 679 potential targets. Biological function analysis showed that there were 12, 19, and 12 GO entries related to biological processes, cell components and molecular functions, respectively. 43 KEGG pathways were identified, of which the most significant categories were terpenoid backbone biosynthesis, TNF signaling pathway and leishmaniasis. The component-target-disease network diagram revealed that the essential oil compositions in leaves of C. grandis ‘Tomentosa’ could treat tumors, immune diseases, neurodegenerative diseases and respiratory diseases, which were highly related to CHRM1, PTGS2, CASP3, MAP2K1 and CDC25B.Conclusion: This study may provide a new insight into C. grandis ‘Tomentosa’ or C. grandis (L.) Osbeck and may provide useful information for future utilization and development.

scholarly journals The Relationship between Glucosinolates and the Sensory Characteristics of Steamed-Pureed Turnip (Brassica Rapa subsp. Rapa L.)

Foods ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 1719
Author(s):  
Nurfarhana Diana Mohd Nor ◽  
Stella Lignou ◽  
Luke Bell ◽  
Carmel Houston-Price ◽  
Kate Harvey ◽  
...  
Keyword(s):  
Bitter Taste ◽  
Dry Weight ◽  
Sweet Taste ◽  
Liquid Chromatography Mass Spectrometry ◽  
Sensory Panel ◽  
Brassica Vegetables ◽  
Different Seasons ◽  
Phytochemical Compounds ◽  
Positive Correlations ◽  
The Relationship

Glucosinolates (GSLs) are phytochemical compounds that can be found in Brassica vegetables. Seven separate batches of steamed-pureed turnip were assessed for GSL content using liquid chromatography mass spectrometry (LC-MS) and for sensory attributes by sensory profiling (carried out by a trained sensory panel). Twelve individual GSLs, which included 7 aliphatic, 4 indole and 1 arylaliphatic GSL, were identified across all batches. There were significant differences in individual GSL content between batches, with gluconasturtiin as the most abundant GSL. The total GSL content ranged from 16.07 to 44.74 μmol g−1 dry weight (DW). Sensory profiling concluded there were positive correlations between GSLs and bitter taste and negative correlations between GSLs (except glucobrassicanapin) and sweet taste. The batches, which had been purchased across different seasons, all led to cooked turnip that contained substantial levels of GSLs which were subsequently all rated as bitter.

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