scholarly journals HYPOGLYCEMIA

2011 ◽  
Vol 18 (01) ◽  
pp. 83-88
Author(s):  
GHAZANFAR ALI SANDHU ◽  
MOHAMMAD MOHSIN RANA ◽  
M. BADAR BASHIR ◽  
Saeed Akthar ◽  
Abedur Rehman

Hypoglycemic symptoms are a very common experience for diabetics ranging from an innocent increased appetite to dreadful unconsciousness. This study was designed to assess the patient’s awareness about the symptoms, experience of individual symptoms and their ability to recognize and to respond accordingly. Materials and Methods: All diabetic patients were assessed for the awareness of different symptoms of hypoglycemia, their experience of individual symptoms in last six months and ability of the patient and family members to recognize and to respond accordingly to these symptoms on a prescribed proforma with the help of trained staff. Results: We had 1260 new cases of DM during the study period with valid diagnosis and taking either sulphonylurea or Insulin who were enrolled in the study. 280 patients had no idea of the symptoms. 564 patients knew no more than three symptoms. Palpitation and sweating were the most commonly known 80% and experienced 65% symptoms. Hunger and epigastric discomfort were the next best known 73% and experienced 58% symptoms. Loss of consciousness was the next in the list in terms of knowledge 52% and experience 23%. Coldness of body 28%, severe weakness 24%, blurred vision 12%, abnormal behavior 12% and altered consciousness 6% were the next in the list of experience. Early morning headache, night terror and frequent awakening were the least known 3% and recognized1% symptoms. Abnormal behavior and altered consciousness were not known to any patient as a symptom. Of those who knew or experienced the symptoms, eating anything available was the most common response, only 35% responded by eating rapidly available food items like sugar, honey, candies, beverages, fruit juice or jams. 3% of patients even resorted to taking diet colas initially and only later took other food after waiting for some time. In the event of patient getting unconscious, 80% of the times attendants did not consider hypoglycemia initially at home at first such experience. Discussion: Patient must be properly educated about these symptoms before prescribing these agents and shall be repeatedly evaluated at each visit. Failing to recognize early and mild symptoms may lead to a terrifying experience.

2019 ◽  
Vol 37 (4) ◽  
pp. 205-208
Author(s):  
Gobinda Chandra Banik ◽  
Sakib Aman ◽  
Farhana Sultana ◽  
Syed Mohammad Arif

  Subacute sclerosing panencephalitis (SSPE) is chronic progressive encephalitis of childhood and young adoloscent due to persistent measles virus infection. This case illustrates a 14 year old girl presented with short history of intellectual decline, abnormal behavior, myoclonus and altered consciousness with suggestive neuroimaging mimicking metachromatic leucodystrophy. Subsequently she was diagnosed to be a case of Subacute sclerosing panencephalitis (SSPE) on the basis of Electroencephalography (EEG) and Cerebrospinal fluid(CSF) measles antibody titer. J Bangladesh Coll Phys Surg 2019; 37(4): 205-208


2016 ◽  
Vol 119 (suppl_1) ◽  
Author(s):  
Muhammad M Ahsan ◽  
Tara Thompson ◽  
Chandralekha Ashangari ◽  
Amer Suleman

Background: Postural Orthostatic Tachycardia Syndrome (POTS) is a form of dysautonomia that is estimated to impact between 1,000,000 and 3,000,000 Americans and millions more around the world. Patients chronically have symptoms that are worse with upright posture and that improve with recumbence. Symptoms often include orthostatic intolerance such as dizziness, fatigue, excessive sweating and many others. The aim of this study is to determine the variation of symptoms early morning after wake up and evening at 4 PM. Methods: The Autonomic nervous system questionnaire consisting of eight POTS symptoms palpitations, headaches, dizziness, shortness of breath(SOB), chest pain, weakness, blurred vision and heaviness of feet was handover to the patients at our clinic. 42 POTS patients participated in the study, participated patients had been asked to scale their symptoms early morning after wake up and evening at 4 PM. Symptoms were defined 0 as Never,1 as mild,2 as moderate,3 as severe ,4 as extreme and 5 impairing daily function and living. Results: Out of 42 POTS patients 90% are female (38/42, age 31.74±10.67) and 10% are males (4/42, age 30.75±13.20), symptoms were scaled early morning after wake up vs symptoms scaled evening at 4 pm results in mean±SD and Anova P value. Palpitations 1.69±1.32 vs 2.45±1.38 (P =0.01), Dizziness 2.40±1.38 vs 2.67±1.46 (P =0.40), Chest pain 0.93±1.02 vs 1.52±1.27 (P=0.02), SOB 1.36±1.32 vs 1.81±1.40 (P=0.13), Weakness 2.79±1.37 vs 3.12±1.38 (P=0.27), Blurred vision 1.38±1.29 vs 1.48±1.27 (P=0.73), Headaches 1.74±1.36 vs 2.52±1.38 (P =0.01), Heaviness of feet 0.95±1.19 vs 1.43±1.53 (P =0.11). Conclusion: Our study results demonstrated that the patients with POTS had significant variation in symptoms Palpitations, Chest pain, Headaches in evenings when compared to early morning after wake up.


2020 ◽  
Vol 1 (1-2) ◽  
pp. 68-85
Author(s):  
Stuart Gietel-Basten

Abstract Very few historical studies have been able to demonstrate the times of day when humans give birth in a ‘natural’ setting—i.e. outside of any hospital context or potential intervention. Two villages in the southwestern Russian Empire present rare examples of nineteenth-century baptism registers where time of birth were recorded. The evidence supports the thesis that ‘natural’ human births disproportionately occur between midnight and early morning. Evidence from the registers also show a seasonal effect, likely driven by the relationship between luminosity and melatonin production. The study, then, contributes to the ongoing debate regarding the medicalisation of childbearing, the deterioration of female autonomy in the sphere of childbearing, as well as other negative health outcomes. Historical evidence can demonstrate how far the circumstances of contemporary society differ from the ‘natural’ mode in something as fundamental as the time of the day when we give birth.


2020 ◽  
Vol 19 (2) ◽  
Author(s):  
Shalihin SE ◽  
Firzada I ◽  
Din MH

Introduction: Long waiting time is a common issue complained by diabetic patients that came for an early morning appointment in a health clinic. Therefore, an audit was conducted among diabetic patients in a primary care clinic with the aim to assess the patients’ waiting time and to formulate strategies for improvement. Methods: This audit was conducted for four weeks using a universal sampling method in November 2017. All diabetic patients who attended the clinic during this period were included except those who required longer period such as critically ill patients or those who came for repeat medication or procedures. The arrival and departure time for each station was captured using the modified waiting time slip, which is manually filled at every station. The waiting and consultation time for registration, screening, laboratory investigation, diabetic educator, doctor and pharmacy were recorded. The data were entered into the statistical software SPSS version 17 for analysis. Results: Results showed that all patients were registered within 11.0 minutes (SD=2.52min). Average total waiting time to see a diabetic educator and a doctor was 20.9 minutes (SD=15.53min) and 33.23 minutes (SD=27.85min), respectively. Average waiting time for other stations was less than 10 minutes. Average total time spend in the clinic for a diabetic patient was 107.58 minutes, which is comparable to a non-diabetic patient. The identified problems were due to the poor tracing and filing system. Conclusion: Improvement strategies recommended include enforcing early file tracing prior to appointment and providing a checklist for consultation by doctors and diabetic educators.


2019 ◽  
Vol 2 ◽  
pp. 732
Author(s):  
Alberth Supriyanto Manurung ◽  
Abdul Halim

Mathematics is the science of logic regarding shapes, structures, quantities, and concepts related to each other. Learning Mathematics in the form of a Mathematical Literacy Movement is not just about increasing curiosity but always developing according to the times, Mathematics subjects aim to instill and develop the process of counting on the teacher. Based on observations in SDN Duri Kepa 05 Early morning in the learning process the teacher still uses conventional teaching methods or teacher-centered as information givers, with the mathematics literacy movement expected to improve the good quality of each concept in the form of problem application. The purpose of this community service activity is to increase learning motivation by applying the Mathematical Literacy Movement in schools and to increase knowledge which changes at any time. The subject of this community service is all Mathematics Teachers in SDN Duri Kepa 05 Pagi. Method of approach to support the realization of Education and Training Understanding of mathematics literacy movements for mathematics teachers includes Theoretical approach (Workshop), Field application approaches, Evaluation approaches. In this activity, it is expected that partner participation is at least 10 Participants registered, and those who attend the workshop are expected to be 100%. In the field guide, it is expected to be 100% guided.


2017 ◽  
Vol 24 (01) ◽  
pp. 126-131
Author(s):  
Muhammad Zakria ◽  
Muhammad Sarfraz ◽  
Touseef Ahmad

Objectives: To determine the frequency of microalbuminuria in patientswith acute ischemic stroke. Study Design: Cross-sectional study. Setting: Medical floor,Independent University Hospital, Marzipura, Faisalabad. Study Duration: Two years, from 1stOctober 2013 to 30th September 2015. Materials and Methods: 95 patients of ischemic stroke,with or without diabetes mellitus and hypertension were tested for early morning urine albuminto creatinine ratio, after excluding patients with raised serum creatinine, urinary tract infection,congestive heart failure and menstruation. A urinary albumin to creatinine ratio of 30 to300 μg/mg was considered as MA. Results: Out of a total of 95 patients, MA was present in 46(48.4%)and absent in 49(51.6%) patients. Out of 33 diabetic patients, MA was present in 18(54.5%)patients while out of 62 non-diabetics 28(45.2%) had MA. Out of 55 hypertensive patients,MA was present in 27(49.1%) while out of 40 non-hypertensives 18(45.0%) had MA. Among14 patients having both diabetes mellitus and hypertension, 8(57.1%) were having MA. Outof 20 patients without both diabetes and hypertension, 8(40.0%) had MA. Conclusion: Giventhe high frequency of microalbuminuria in patients with ischemic stroke, microalbuminuria is auseful modifiable factor in addition to conventional risk factors in identifying those at increasedrisk of ischemic stroke.


Author(s):  
Sai Laxmi M. ◽  
Venkatesham A. ◽  
A. Rama Narsimha Reddy ◽  
Shankaraiah P. ◽  
Krishna D. R. ◽  
...  

Glibenclamide is a second generation sulfonylurea used in the treatment of type 2 diabetes. The study included 57 type 2 diabetic patients of either sex, aged above 21 years, an who were under treatment with glibenclamide. Blood samples were collected after 2 hours of drug intake and the next day, early morning before taking the drug. Serum glucose levels and glycosylated hemoglobin levels were estimated. The effect of glibenclamide treatment on long-term glycemic control was studied. There was no correlation between peak serum drug concentrations and post prandial glucose level as well as between trough serum drug and fasting glucose concentrations as could be observed from the coefficient of correlation (R2) values of 0.0319 and 0.0013, respectively. There is no correlation between peak serum drug concentration and HbA1c% as can be observed from the R2 value of 0.0101.The insignificant correlation between the parameters indicates that upon chronic therapy with glibenclamide desensitization and receptor down regulation occurs leading to loss of glycemic control. It was observed that the increased dose of glybenclamide also did not improve glycemic control.


2015 ◽  
Vol 47 (3) ◽  
pp. 238-244 ◽  
Author(s):  
Tetsuro Tsujimoto ◽  
Ritsuko Yamamoto-Honda ◽  
Hiroshi Kajio ◽  
Miyako Kishimoto ◽  
Hiroshi Noto ◽  
...  

2016 ◽  
Vol 37 (4) ◽  
pp. 2053 ◽  
Author(s):  
Viviane Da Silva Hampel ◽  
Marta Gomes da Rocha ◽  
Luciana Pötter ◽  
Sheila Cristina Bosco Stivanin ◽  
Marcos Bernardino Alves ◽  
...  

We evaluated the grazing behavior of heifers, at two phenological stages (vegetative and reproductive) of ryegrass (Lolium multiflorum Lam.), in four times of the day (early morning, morning, evening, and night), with heifers either exclusively grazing or with oat, or corn grain, supplementation. The experimental design was completely randomized, in sub-subdivided plot arrangement, in which the main plots were the feeding systems, the sub-plots were the phenological stages and the sub-sub-plots were the times of day. We assessed ingestion behavior along 24 hours through visual observation, on four evaluation dates, two during the vegetative stage and two during the reproductive stage, studying time spent on grazing, rumination, or other activities, as well as number and duration of, and interval between meals. Supplemented heifers remained less time at a feeding station, performed fewer bites daily and, during the reproductive stage of the ryegrass, spent more time in other activities. Grazing time of supplemented heifers was shorter in the morning and at night, and the duration of their meals was shorter at night. A change occurred in the pattern of time use when heifers received supplement, and when the structural and qualitative characteristics of the pasture changed during the vegetative and reproductive phenological stages of ryegrass.


2019 ◽  
Vol 17 (01) ◽  
pp. 61-65
Author(s):  
Sanjay Kumar Thakur ◽  
Sukesh Purush Dhakal ◽  
Shreeya Parajuli ◽  
Anil Kumar Sah ◽  
Suresh Prasad Nepal ◽  
...  

Background: Diabetic nephropathy is one of the dreaded complications of diabetes leading to chronic kidney disease and end stage renal failure globally. Microalbuminuria is the most sensitive marker of early recognition of the diabetic nephropathy. This study was carried out to find out the prevalence and potential risk factors of microalbuminuria which is the marker of diabetic nephropathy among diabetes patients in Nepal. Methods: A cross-sectional study was conducted on a random sample of 227 in T2DM patients in private diabetic clinics and Bir hospital in Kathmandu. Data were collected using standard questionnaire format to collect demography, anthropometry, and laboratory assessment of, HbA1c, post prandial, fasting glucose and micro albumin in urine. Micro albuminuria was measured using early morning urine specimen. Micro albuminuria was considered positive when urinary albumin to creatinine ratio was found to be 30–300 mg/g creatinine in preferably an early morning or a spot urine sample. The entire lab test will be done by applying the internationally accepted standards of tools and techniques.Those that were reported >30mg/mL of micro albumin were considered as positive. Results:  Out of total 217 diabetic patients, 56.2% (122/217) were male and 43.8% (95/217) were female. Among all age groups, maximum patients enrolled were between the age group 41 to 80 (95%).Of the total, 20% (44/217)) patientswereMA positive. A statistical significant association was seen between MA and BMI (p=0.029), duration of DM (p=<0.001, hypertension (p=<0.001, smoking (p=<0.001) and physical activity (p=<0.001). Conclusions: Diabetic patients in Nepal have prevalence of 20.3% microalbuminurea. Hypertension, obesity, sedentary lifestyles, duration more than 5 years of illness are found the most important risk factors for the development of microalbuminurea in diabetes.     Keywords:  Mellitus; microalbuminuria; type 2 diabetes


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