scholarly journals CENTRAL CORNEAL THICKNESS

2018 ◽  
Vol 25 (02) ◽  
pp. 252-260
Author(s):  
Muhammad Ijaz Ahmad ◽  
Manzoor Ahmad Qureshi ◽  
Muhammad Shakeel Ahmad ◽  
Yousef Homood Aldebasi
Keyword(s):  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Mean Value ◽  
T Test ◽  
Kingdom Of Saudi Arabia ◽  
Cross Sectional ◽  
Ultrasound Pachymetry ◽  
Significant Difference ◽  
The Mean ◽  
Ultrasonic Pachymetry

Objectives: To compare central corneal thickness in myopic and keratoconuseyes by ultrasound pachymetry and pentacam HR. Study Design: Cross sectional study.Setting: Qassim University, Optometry Clinics, Kingdom of Saudi Arabia. Period: October2016 to April 2017. Methodology: One hundred myopic and keratoconus participants. CentralCorneal Thickness (CCT) were measured with two techniques by ultrasonic pachymetry andpentacam HR in two groups. Group one consisted of 80 myopic participants and group two of 20Keratoconuspatients.Pentacamreadings were recorded first. CCT were compared and analyzedstatistically using unpaired t-test and histogram. Results: One hundred participants (100) wereincluded in which 80 participants were myopic and 20 with keratoconus. Both eyes (200) of allthe participants were examined. Age of the myopics ranged from 18-30 years (Mean=23.03).The mean value with ultrasound pachymetery was 555μm (SD±32.021) and with pentacam566μm (SD±37.367). We observed a tendency of overestimation of CCT measurements withpentacam. Statistically a significant difference of reading between two devices (P<0.001) wasfound. In keratoconus participants, the mean age was 23.7 years (21- 26). The mean CCT takenwith Pentacam HR and US Pachymetry was 476μm (SD± 16.980) and 465μm (SD± 35.868)respectively. The t-test showed no statistical difference between thepentacam HR andultrasound pachymetry (p>0.214). Conclusion: Measurements of central corneal thicknessdone with Ultrasound Pachymeter and Pentacam HR are closely related to each other andare interchangeable when used in normal refractive error cases. While in Keratonus patientsultrasound pachymetry is preferred because of its reliability.

scholarly journals Usefulness of the Non-Contact Tonometry in Out-Patient Screening

2016 ◽  
Vol 15 (2) ◽  
Author(s):  
Satheesh Solomon T Selvin ◽  
Chris Elsa Samson Jacob ◽  
Thomas Kuriakose
Keyword(s):  
Central Corneal Thickness ◽  
Care Center ◽  
Corneal Thickness ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Applanation Tonometry ◽  
Cross Sectional ◽  
Significant Difference ◽  
Iop Measurement ◽  
The Mean

Purpose: Goldmann applanation tonometry (GAT) is considered the gold standard for Intraocular Pressure (IOP) measurement. It has the disadvantages of being a contact device, need for a slit-lamp, non-portability and need of a skilled examiner. Many hospitals are using a Non Contact Tonometry (NCT) as a screening device to save clinician time, however the usefulness is not proved in terms of reliability. This study was aimed to determine the usefulness of the Air-puff tonometer (TONOREF NIDEK II, NIDEK CO., LTD., JAPAN) over a GAT in a tertiary care center. Design: Cross-sectional Study Methods: This was a cross-sectional, non interventional observational study conducted on 224 eyes (right eye) from 224 patients. All patients underwent the IOP measurement with both methods and a central corneal thickness (CCT) measured. The data was analyzed using SPSS 20.0 software. Results: The mean age of the patients was 40.3±11.29 years. There was a statistically significant difference (p<0.001) between the mean NCT and GAT readings which persisted even after correction for central corneal thickness. The correlation between NCT and GAT using Pearson’s correlation coefficient was strong irrespective of the corrections for their corneal thickness (r = 0.751 and 0.718 for uncorrected and corrected values respectively). The correlation of the individual clinicians for the readings varied from moderate to strong. The ROC curve showed the best sensitivity and specificity to occur at around 13 to 14 mmHg. Conclusion: NCT seems to overestimate the IOP at low ranges as compared to the GAT and underestimate at higher ranges. The crossover of the values is seen between 12 to 13 mmHg.  The clinician should do an individualized analysis of his/her GAT measurements to the readings of the NCT machine at the clinic to obtain clinician specific nomogram. 

scholarly journals The pattern of central corneal thickness in patients attending a Tertiary Hospital in Dar-Es-Salaam

2021 ◽  
Vol 9 (2) ◽  
pp. 127-133
Author(s):  
Annamary Stanislaus ◽  
Ntsilane Susan Mosenene ◽  
Celina Mhina ◽  
John Stanslaus Kisimbi ◽  
Frederick Robert Burgess ◽  
...  
Keyword(s):  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Dar Es Salaam ◽  
Applanation Tonometry ◽  
P Value ◽  
Muhimbili National Hospital ◽  
National Hospital ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Mean

Background: Central Corneal Thickness (CCT) is an indicator of corneal health status as well as being an essential tool in assessment and management of corneal diseases. It is an important factor in the diagnosis and management of glaucoma as it affects the measurement of intraocular pressure. However, the pattern of central corneal thickness in our population is not known. Our study aimed to describe the CCT measurements and their variation with age and sex among patients attending the eye clinic at Muhimbili National Hospital (MNH), in Dar es Salaam, Tanzania. Methodology: A hospital-based descriptive, cross-sectional study used convenient sampling to recruit adult patients aged 18 years and above, presenting to the MNH between August 2016 and January 2017.Visual acuity assessment, Goldman applanation tonometry and CCT assessment using an ultrasound pachymeter were performed. Patients with previous intraocular surgery were excluded. Results: A total of 398 patients (208 males and 190 females) were recruited. The mean CCT was 526.64±38.30 µm; being 523.99±38.20 µm for males and 529.7±38.3 µm for females. 226 (56.85%) had CCT of less than 520 µm.There was no statistically significant difference in CCT between gender. The proportion of patients with thinner CCT increased with increasing age from 25.8% in those < 30 years to 75% in those aged 71years and above. The mean CCT decreased with increasing age with P-value<0.001. Conclusion: The average CCT in patients attending Muhimbili National Hospital is 526.64 µm (SD 38.30) which is generally thin, inversely proportion to age and similar that of other Africans and African-Americans. This finding has implications for the management of glaucoma in this population.

scholarly journals Sirius Scheimpflug–Placido versus ultrasound pachymetry for central corneal thickness: meta-analysis

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Yili Jin ◽  
Colm McAlinden ◽  
Yong Sun ◽  
Daizong Wen ◽  
Yiran Wang ◽  
...  
Keyword(s):  
Central Corneal Thickness ◽  
Meta Analysis ◽  
Corneal Thickness ◽  
Mean Difference ◽  
Cochrane Library ◽  
Ultrasound Pachymetry ◽  
Significant Difference ◽  
The Mean ◽  
The Difference ◽  
Clinically Significant

Abstract Background To compare the difference in central corneal thickness (CCT) measurements in normal eyes between a rotating Scheimpflug camera combined with a Placido-disk corneal topographer (Sirius, CSO, Italy) and ultrasound pachymetry (USP). Methods A systematic literature search was conducted for relevant studies published on PubMed, Medline, EMBASE, and the Cochrane Library and ClinicalTrials.gov from inception to August 1st, 2019. Primary outcome measures were CCT measurements between Sirius and USP. A random effects model was used to pool CCT measurements. Results A total of twelve studies involving 862 eyes were included in this meta-analysis. The meta-analysis found CCT measurements between Sirius and USP to be statistically significantly different (P < 0.0001). The mean difference between Sirius and USP was −11.26 μm with a 95% confidence interval (CI) (−16.92 μm, −5.60 μm). The heterogeneity was I2 = 60% (P = 0.004). Conclusion CCT measurements with the Sirius Scheimpflug-Placido topographer were statistically significantly lower than USP. However, it may be argued that the mean difference of 11.26 μm is not a clinically significant difference.

scholarly journals Difference in Central Corneal Thickness between Applanation Ultrasound and Oculus Wave � 152 Light Occulyzer II

2019 ◽  
Vol 35 (3) ◽  
Author(s):  
Munira Shakir, Ronak Afza Memon Sahira Wasim Shakir Zafar
Keyword(s):  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Clinical Settings ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Ultrasound Pachymetry ◽  
Department Of Ophthalmology ◽  
The Mean ◽  
Thickness Measurements ◽  
Applanation Ultrasound

Purpose: To determine the mean difference of central corneal thickness measurements by using ultrasound Pachymetry and oculus Wave light Occulyzer II. Study Design: Cross-sectional comparative study using non-probability consecutive sampling. Place and Duration of Study: This study was conducted at Department of Ophthalmology, Liaquat National Hospital Karachi from November 2018 to June 2019. Material & Methods: After approval from ethical committee, patients were included in our study on the basis of inclusion & exclusion criteria. Central corneal thickness measurements were taken by using ultrasound Pachymetry & oculus Wave light Occulyzer II. All the data was collected by single researcher. The results were plotted, compared & analyzed. Paired t-test was used for the comparison of quantitative variables. Results: There were 130 patients included in the study out of which 73 (56.2%) were males and 57 (43.8%) were females. Mean age of these patients was 33.9 � 8.9 years. The mean � SD thinnest oculus Wave light Occulyzer II measurement was 538.61 � 23.46 ?m and ranged between 476.0 and 619.0 ?m whereas the mean thinnest ultrasound Pachymetry measurement was 535.1 � 21.816 ?m and ranged between 482 and 601 ?m. There was highly significant correlation of central corneal thickness between both the instruments. (r = 0.96, p < 0.001). Conclusion: There is a high correlation of central corneal thickness between the readings obtained from ultrasound and optical pachymetry machines therefore oculus Wave light Occulyzer II can be used as an alternative technique to ultrasound pachymetry while assessing CCT in clinical settings. Key Words: Central corneal thickness, Ultrasound Pachymetry, Optical Pachymetry.

scholarly journals Evaluation of the relation between myopia and central corneal thickness in patients admitted to vali-e-asr hospital in birjand, iran

2021 ◽  
pp. 138-143
Keyword(s):  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Epidemiologic Study ◽  
T Test ◽  
P Value ◽  
Study Results ◽  
Significant Difference ◽  
The Mean ◽  
And Gender ◽  
The Right

Introduction: Considering the increasing prevalence of myopia and the subsequent complications, and due to the dearth of studies on the correlation between myopia and gender with corneal thickness in Iran, this study aimed to determine this relationship in patients admitted to the ophthalmic clinic of Vali-e-Asr Hospital, Birjand, Iran. Methods: This descriptive-analytic epidemiologic study was conducted on 100 patients admitted to Vali-e-Asr ophthalmic clinic in Birjand, Iran, for one year since January 2017. According to the degree of myopia, the patients were divided into three groups of low (0-3 D), moderate (3-6 D), and high myopia (6≤D). Corneal thickness was measured using Orbscan and Pentacam. The data were analyzed in SPSS software (Version 19) through ANOVA and T-test to determine the possible relationship between myopia and central corneal thickness. A p-value equal to and less than (P≤0.05) was considered statistically significant. Results: Overall, 100 patients (49 males and 51 females) were enrolled in this study. Moderate myopia had the highest frequency in both eyes. The results of the T-test revealed that no significant difference was observed in the mean corneal thickness measured by Pentacam between the two genders (P=0.18 in the right eye and P=0.32 in the left eye). Based on the ANOVA findings, the mean corneal thickness measured by Pentacam was not significantly different among the myopia categories (P=0.05 in the right eye and P=0.51 in the left eye) Conclusions: The study results revealed that there was no significant relationship between myopia and gender with corneal thickness.

scholarly journals Corneal Biomechanical Parameters and Central Corneal Thickness in Glaucoma Patients, Glaucoma Suspects, and a Healthy Population

2021 ◽  
Vol 10 (12) ◽  
pp. 2637
Author(s):  
Mª. Ángeles del Buey-Sayas ◽  
Elena Lanchares-Sancho ◽  
Pilar Campins-Falcó ◽  
María Dolores Pinazo-Durán ◽  
Cristina Peris-Martínez
Keyword(s):  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Mean Difference ◽  
The Other ◽  
Control Group ◽  
Healthy Population ◽  
Diagnostic Categories ◽  
Significant Difference ◽  
Biomechanical Parameters ◽  
The Mean

Purpose: To evaluate and compare corneal hysteresis (CH), corneal resistance factor (CRF), and central corneal thickness (CCT), measurements were taken between a healthy population (controls), patients diagnosed with glaucoma (DG), and glaucoma suspect patients due to ocular hypertension (OHT), family history of glaucoma (FHG), or glaucoma-like optic discs (GLD). Additionally, Goldmann-correlated intraocular pressure (IOPg) and corneal-compensated IOP (IOPcc) were compared between the different groups of patients. Methods: In this prospective analytical-observational study, a total of 1065 patients (one eye of each) were recruited to undergo Ocular Response Analyzer (ORA) testing, ultrasound pachymetry, and clinical examination. Corneal biomechanical parameters (CH, CRF), CCT, IOPg, and IOPcc were measured in the control group (n = 574) and the other groups: DG (n = 147), FHG (n = 78), GLD (n = 90), and OHT (n = 176). We performed a variance analysis (ANOVA) for all the dependent variables according to the different diagnostic categories with multiple comparisons to identify the differences between the diagnostic categories, deeming p < 0.05 as statistically significant. Results: The mean CH in the DG group (9.69 mmHg) was significantly lower compared to controls (10.75 mmHg; mean difference 1.05, p < 0.001), FHG (10.70 mmHg; mean difference 1.00, p < 0.05), GLD (10.63 mmHg; mean difference 0.93, p < 0.05) and OHT (10.54 mmHg; mean difference 0.84, p < 0.05). No glaucoma suspects (FHG, GLD, OHT groups) presented significant differences between themselves and the control group (p = 1.00). No statistically significant differences were found in the mean CRF between DG (11.18 mmHg) and the control group (10.75 mmHg; mean difference 0.42, p = 0.40). The FHG and OHT groups showed significantly higher mean CRF values (12.32 and 12.41 mmHg, respectively) than the DG group (11.18 mmHg), with mean differences of 1.13 (p < 0.05) and 1.22 (p < 0.001), respectively. No statistically significant differences were found in CCT in the analysis between DG (562 μ) and the other groups (control = 556 μ, FHG = 576 μ, GLD = 569 μ, OHT = 570 μ). The means of IOPg and IOPcc values were higher in the DG patient and suspect groups than in the control group, with statistically significant differences in all groups (p < 0.001). Conclusion: This study presents corneal biomechanical values (CH, CRF), CCT, IOPg, and IOPcc for diagnosed glaucoma patients, three suspected glaucoma groups, and a healthy population, using the ORA. Mean CH values were markedly lower in the DG group (diagnosed with glaucoma damage) compared to the other groups. No significant difference was found in CCT between the DG and control groups. Unexpectedly, CRF showed higher values in all groups than in the control group, but the difference was only statistically significant in the suspect groups (FHG, GLD, and OHT), not in the DG group.

scholarly journals Model Pengembangan Pembelajaran PJBL Berbasis Proyek untuk Meningkatkan Kreatifitas Siswa

2021 ◽  
Vol 3 (2) ◽  
pp. 140-147
Author(s):  
Nana Misrochah
Keyword(s):  
Data Analysis ◽  
Mean Value ◽  
T Test ◽  
Acid Base ◽  
Paired Sample ◽  
Cooking Oil ◽  
Achievement Rate ◽  
Significant Difference ◽  
Acid Base Titration ◽  
The Mean

Through this research, it is hoped that acid-base titration learning will be more meaningful and can contribute to student creativity. PjBL model is an integrated learning that is carried out cooperatively through projects that develop student skills, so that student creativity will increase. The project given in this research is making of soap from the wrinkled oil. In the process can be attributed to the application of acid-base titration material by calculation of acid numbers and saponification numbers on the cooking oil before being processed into soap. The results of data analysis shows data significance> 0.05 which means that the data is normally distributed for pretest and posttest. The data of paired sample t-test shows that the significance obtained is 0,000 <0.05 which means that there is a significant difference between the mean value of the integrated creativity test with the acid-base titration concept before treatment is given after treatment is given. Creativity improvement were calculated using the N-Gain value resulting in an average achievement rate of 0.50 and belonging to the moderate category. Posttest results indicate that the implementation of project-based LKP is effective in improving student creativity with classically average is 81.5%.

scholarly journals IgM Anti PGL-1 Antibody Level in Patients with Leprosy: A Comparative Study between Ear Lobes Capillary and Median Cubital Vein Blood Samples

2018 ◽  
Vol 6 (8) ◽  
pp. 1346-1348
Author(s):  
Khairina Nasution ◽  
Kristina Nadeak ◽  
Syahril Rahmat Lubis
Keyword(s):  
Blood Sample ◽  
Filter Paper ◽  
Cross Sectional Study ◽  
Mean Value ◽  
Cross Sectional ◽  
Blood Samples ◽  
Significant Difference ◽  
Median Cubital Vein ◽  
The Mean ◽  
Antibody Levels

BACKGROUND: To establish the diagnosis of leprosy accurately, additional examination such as serologic examination with ELISA is required. There are considerations about taking a blood sample from the earlobe region.AIM: To determine the differences in IgM anti-PGL-1 antibody levels from earlobe capillary and median cubital vein blood sample in leprosy patients.METHODS: An observational analytic study using a cross-sectional study involving 30 patients with leprosy. ELISA examination of earlobe blood samples with filter paper, and the median cubital vein blood samples with filter paper and conventional methods were performed to determine IgM anti-PGL-1 antibody levels.RESULTS: The mean value of IgM anti PGL-1 antibody levels from earlobe blood samples with filter paper (1476.62 μ/ml) was relatively similar with median cubital vein blood samples with conventional method (1476.77 μ/ml), but the mean value of IgM anti PGL-1 antibody levels from median cubital vein blood samples with filter paper (1210.37 μ/ml) was lower from other methods. However, there was no statistically significant difference between them.CONCLUSION: There are no significant differences between the mean levels of IgM anti-PGL-1 antibody from earlobe and the median cubital vein blood samples.

scholarly journals Reference values of the central corneal thickness with different refractive errors for the adult Egyptian population

2020 ◽  
Author(s):  
Amr A. Gab-Alla
Keyword(s):  
Reference Values ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Cross Sectional Study ◽  
Refractive Errors ◽  
Spherical Equivalent ◽  
Sectional Study ◽  
Cross Sectional ◽  
Egyptian Population ◽  
The Mean

Abstract Background: To generate reference values of the central corneal thickness (CCT) with different refractive errors for the adult Egyptian population. Methods: A retrospective, observational, and cross-sectional study of 2200 eyes in 1166 subjects scheduled for LASIK, who came to private refractive eye center, Ismailia, Egypt. The study period was from January 2018 to January 2020. The subjects were divided into a broad range of myopia with spherical equivalent (SE) <-0.5D and hyperopia SE> +0.5D. Then, the myopic eyes divided into low (SE>-3.0D), moderate (SE-3.0D to >-6.0D), and high (SE<-6.0D). Similarly, the hyperopic eyes were divided into low (SE<+3.0 D) and moderate (SE+3.0D to <+6.0D) and high >+6.0D. The refractive error was measured by an auto-refractometer (Topcon, Tokyo Optical Co., Ltd., Japan), and CCT was measured using Sirius (CSO, Florence, Italy). Results: The data of 1100 myopic eyes in 556 subjects (30.5% males and 69.5% females) and 1100 hyperopic eyes in 610 subjects (33.6% males and 66.4% females). The mean+SD of CCT for the total myopic subjects was 531.98+32.92μm, range (406 to 636μm). The mean+SD of SE was -4.1±2.5D, range (-0.5 to -12.0D). The mean+SD of CCT for the total hyperopic subjects was 529±38.8μm, range (448 to 619 μm). The mean+SD of SE was +3.65+1.97D, range (+0.5 to +8.5D).Conclusion: In this study, the mean of CCT of the Egyptian population was 531.9 μm for myopic and 529μm for hyperopic subjects respectively. The myopic and hyperopic subjects show a reduction in CCT with age. Females have a thinner cornea than males, 23.6% of the myopic eyes, and 16.5% of the hyperopic eyes have CCT less than 500μm.

scholarly journals Comparison of Central Corneal Thickness Measurements between Angiovue Optical Coherence Tomography, Ultrasound Pachymetry and Ocular Biometry

2020 ◽  
pp. 1-9
Author(s):  
E. Pateras ◽  
A. I. Kouroupaki
Keyword(s):  
Optical Coherence Tomography ◽  
Central Corneal Thickness ◽  
Corneal Thickness ◽  
Repeated Measurements ◽  
Optical Coherence ◽  
Swept Source ◽  
Ocular Biometry ◽  
Significant Linear Correlation ◽  
Ultrasound Pachymetry ◽  
The Mean

Purpose: To compare central corneal thickness (CCT) measurements and their reproducibility when taken by Ultrasound Pachymetry, Ocular Biometry and Angiovue Optical Coherence Tomography (OCT). Methods: Twenty-five healthy volunteers were recruited creating a sample size of 50 eyes. All subjects had pachymetric measurements by Ultrasound pachymetry (PachPen Handheld Pachymeter, Keeler Instruments Inc), Ocular biometry (IOL Master 700 Swept Source Biometry, Zeiss) and Angiovue Optical Coherence Tomography (Optovue Avanti RTVue XR Angiovue). The measurements of central corneal thickness for the three devices were taken by the same examiner twice for more accuracy. Results: The average measurements of central corneal thickness by Ultrasound pachymetry (PachPen Handheld Pachymeter, Keeler Instruments Inc), Ocular biometry (IOL Master 700 Swept Source Biometry, Zeiss) and Angiovue Optical Coherence Tomography (Optovue Avanti RTVue XR Angiovue) were 547.26 μm, 551.36 μm, and 536.42 μm, respectively. The mean standard deviation (SD) of repeated measurements by Ocular biometry was 48.87 μm, which was greater than the mean SD of 44.24 μm and 40.35 μm (P < 0.001) by ultrasound pachymetry and Angiovue optical coherence tomography, respectively. There were statistically significant differences in the measurement results among the 3 methods (Ultrasound pachymetry vs. Ocular biometry P = 0.019; Ultrasound pachymetry vs. Angiovue Optical Coherence Tomography; P < 0.001; Ocular biometry vs. Angiovue Optical Coherence Tomography P < 0.001). There was a significant linear correlation between the Ultrasound pachymetry and Ocular biometry (r = 0.945, P<0.001), Ultrasound pachymetry and Angiovue Optical Coherence Tomography (r = 0.895, P<0.001), and Ocular biometry and Angiovue Optical Coherence Tomography (r = 0.902, P<0.001). Conclusion: Central corneal thickness readings were comparable between PachPen Handheld Pachymeter, IOL Master 700 Biometry and Angiovue Optical Coherence Tomography; Angiovue optical coherence tomography gave significantly smaller values. The measurements of the 3 methods showed significant linear correlations with one another. All methods provided acceptable repeatability of measurements.

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