scholarly journals IgM Anti PGL-1 Antibody Level in Patients with Leprosy: A Comparative Study between Ear Lobes Capillary and Median Cubital Vein Blood Samples

2018 ◽  
Vol 6 (8) ◽  
pp. 1346-1348
Author(s):  
Khairina Nasution ◽  
Kristina Nadeak ◽  
Syahril Rahmat Lubis
Keyword(s):  
Blood Sample ◽  
Filter Paper ◽  
Cross Sectional Study ◽  
Mean Value ◽  
Cross Sectional ◽  
Blood Samples ◽  
Significant Difference ◽  
Median Cubital Vein ◽  
The Mean ◽  
Antibody Levels

BACKGROUND: To establish the diagnosis of leprosy accurately, additional examination such as serologic examination with ELISA is required. There are considerations about taking a blood sample from the earlobe region.AIM: To determine the differences in IgM anti-PGL-1 antibody levels from earlobe capillary and median cubital vein blood sample in leprosy patients.METHODS: An observational analytic study using a cross-sectional study involving 30 patients with leprosy. ELISA examination of earlobe blood samples with filter paper, and the median cubital vein blood samples with filter paper and conventional methods were performed to determine IgM anti-PGL-1 antibody levels.RESULTS: The mean value of IgM anti PGL-1 antibody levels from earlobe blood samples with filter paper (1476.62 μ/ml) was relatively similar with median cubital vein blood samples with conventional method (1476.77 μ/ml), but the mean value of IgM anti PGL-1 antibody levels from median cubital vein blood samples with filter paper (1210.37 μ/ml) was lower from other methods. However, there was no statistically significant difference between them.CONCLUSION: There are no significant differences between the mean levels of IgM anti-PGL-1 antibody from earlobe and the median cubital vein blood samples.

scholarly journals Ovarian Reserve In Infertile Women with and without Endometriosis Measured with Anti Müllerian Hormone

2016 ◽  
Author(s):  
Naivah Harharah
Keyword(s):  
Ovarian Reserve ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Exclusion Criteria ◽  
Cross Sectional ◽  
Blood Samples ◽  
Infertile Women ◽  
Significant Difference ◽  
The Mean ◽  
The Difference

Objective: To compare serum Anti Müllerian Hormone (AMH) levels in infertile women with and without endometriosis, and to determine the mean levels of serum AMH in every stage of endometriosis. Method: We performed a cross-sectional study. Sixty-eight subjects who have undergone laparoscopy and fulfilled both inclusion and exclusion criteria are recruited consecutively. They are divided into two groups, namely group with endometriosis and without endometriosis. Blood samples are taken from each subject before laparoscopy, where serum AMH levels are then measured. The difference in mean levels of each group are tested with Mann-Whitney test. Result: The mean levels of serum AMH were significantly lower in the endometriosis group than those in the group without endometriosis (2.30 1.8 ng/ml vs 3.75 2.13 ng/ml; p=0.005). Using Kruskal-Wallis test, it was found that there was a statistically significant difference among endometriosis groups based on the severity of endometriosis. There was no significant difference in the mean serum AMH levels between the minimal-mild endometriosis group and without endometriosis group (p=0.34), but the mean levels of serum AMH were significantly lower in the moderate-severe endometriosis compare to the group without endometriosis (p

scholarly journals Levels of Thyroid Peroxidase Antibodies is Higher in Threatened Abortion

2016 ◽  
pp. 134-138
Author(s):  
I Nyoman A. Sanjaya ◽  
Syarif T Hidayat
Keyword(s):  
Serum Levels ◽  
Normal Pregnancy ◽  
Cross Sectional Study ◽  
Thyroid Peroxidase ◽  
Cross Sectional ◽  
Thyroid Peroxidase Antibody ◽  
Significant Difference ◽  
Threatened Abortion ◽  
The Mean ◽  
Antibody Levels

Objective: To assess the relationship between the incidence of threatened abortion with serum levels of TPO antibodies. Methods: This was cross-sectional study involving subjects 40 cases and 40 controls. The study was conducted September 2012 to November 2012. The difference in the levels of thyroid peroxidase antibody was tested by Mann-Whitney test. Result: In this study, hypothyroidism was found only in the abortion group, as many as 6 subjects (15%) and subclinical hypothyroidism was more prevalent in threatened abortion group, found in 2 people (5%), compared to normal pregnant group, found in only 1 person (2.5%). This study revealed a significant difference in the mean levels of TPO antibodies in the threatened abortion and normal pregnancy group. The mean levels of TPO antibodies in threatened abortion group was 91.76 ± 133.18 IU/ml with the lowest level of 14.41 IU/ml and the highest levels of 534.47 IU/ml while in the normal pregnancy group found an average 12.97 ± 3.91 IU/ml with the lowest value 2.02 IU/ml and the highest value of 20.78 IU/ml. In this study, subjects with TPO antibody levels ≥ 125 IU/ml, all of them experienced threatened abortion (n = 7) and found the risk of miscarriage by 2.212-fold compared with subjects with TPO levels < 125 IU/ml. Conclusion: There are differences in the levels of TPO antibodies in patients with threatened abortion and in normal pregnancies, with average levels of TPO antibodies in imminent abortion group is higher than normal pregnancy group. There is a relationship between TPO antibody levels ≥ 125 IU/ml with the incidence of threatened abortion, with the risk of threatened abortion increasing 2.212 times. [Indones J Obstet Gynecol 2013; 1-3: 134-8] Keywords: threatened abortion, thyroid peroxidase antibody (TPO)

scholarly journals Interleukin-37 as an anti-inflammatory cytokine: does its relation to disease activity suggest its potential role in rheumatoid arthritis therapy?

2021 ◽  
Vol 48 (1) ◽  
Author(s):  
Eman A. Baraka ◽  
Mona G. Balata ◽  
Shereen H. Ahmed ◽  
Afaf F. Khamis ◽  
Enas A. Elattar
Keyword(s):  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Cross Sectional Study ◽  
Healthy Controls ◽  
Tender Joint ◽  
Cross Sectional ◽  
Reactive Protein ◽  
Significant Difference ◽  
The Mean ◽  
Anti Inflammatory

Abstract Background This study aimed to measure the serum and synovial interleukin (IL)-37 levels in rheumatoid arthritis (RA) patients compared to patients with primary knee osteoarthritis (PKOA) and healthy controls and to detect its relation to RA disease activity. Results This cross-sectional study included 50 RA patients with a mean age of 40.24 ± 8.62 years, 50 patients with PKOA with a mean age of 56.69 ± 4.21, and 40 healthy controls with a mean age of 41.75 ± 7.38 years. The mean serum IL-37 level in the RA patients (382.6 ± 73.97 pg/ml) was statistically significantly (P < 0.001) the highest among the studied groups; however, it showed a non-significant difference between the PKOA patients (70.38 ± 27.49 pg/ml) and the healthy controls (69.97 ± 25.12 pg/ml) (P > 0.94). Both serum and synovial IL-37 levels were significantly positively correlated with disease activity scores (r = 0.92, P< 0.001 and r = 0.85, P < 0.001), tender joint counts (r = 0.83, P < 0.001 and r = 0.82, P < 0.001 ), swollen joint counts (r = 0.72, P < 0.001 and r = 0.60, P < 0.001), visual analog scale (r = 0.82, P < 0.001 and r = 0.82, P < 0.001), erythrocyte sedimentation rate (r = 0.75, P < 0.001 and r = 0.65, P < 0.001), and C-reactive protein (r = 0.93, P < 0.001 and r = 0.79, P < 0.001), respectively. Conclusion Serum and synovial IL-37 were significantly elevated in the RA patients, and they were closely correlated. Being less invasive, the serum IL-37 could be a marker of disease activity and could reflect the effective disease control by drugs. Having an anti-inflammatory effect could not suggest IL-37 as the key player to control inflammation alone, but its combination with other anti-proinflammatory cytokines could be investigated.

Comparative assessment of odontometric parameters for gender determination: A hospital based cross-sectional study

2021 ◽  
Vol 8 (3) ◽  
pp. 147-152
Author(s):  
Mosmi Lomi ◽  
Jonathan Daniel M
Keyword(s):  
Sexual Dimorphism ◽  
Cross Sectional Study ◽  
Mean Value ◽  
The Body ◽  
Central Incisor ◽  
Maxillary Canine ◽  
Cross Sectional ◽  
Mean Values ◽  
Gender Determination ◽  
Significant Difference

Determining gender is one of the most important procedure in forensics. Teeth are made of the most enduring mineralized tissues in the body, as such, they have an extraordinary resistance to putrefaction and the effects of external agents (physical, thermal, mechanical, chemical or biological) which makes them invaluable material for anthropological, genetic, odontologic and forensic examinations.i)To assess the degree of sexual dimorphism in maxillary canine using maxillary canine index, maxillary first molar and central incisor using mesiodistal (MD) and buccolingual/buccopalatal (BL) dimensions of the crown. ii) To determine the accuracy of maxillary canine index, first molar and central incisor dimensions (mesiodistal and buccolingual/buccopalatal) in determining sex.This study consisted of total 30 participants (males=15, females=15) of age group ranging from 20 to 35 yrs. Measurement of dimensions of selected teeth were performed on maxillary cast using digital Vernier caliper, resolution 0.01mm. Data thus obtained were analyzed statistically.The mean values of all the measurements in males were greater than females. There was statistical significant difference in mean value of bucco-lingual width of molar, mesiodistal width of canine (on left side, right side and average) and the inter-canine distance between males and females. The buccolingual width of molar showed the highest % of sexual dimorphism (5.33%) and the mesiodistal width of molar showed the least % of dimorphism (0.7%). Bucco-lingual width of molar posed the highest prediction accuracy for gender determination. We conclude that buccolingual width of maxillary first molar can be used to predict the gender when only teeth of maxillary arch are available for forensic examination.

scholarly journals Differences in phosphatemia and frequency of consumption of dietary sources of phosphorus in hemodialysis patients in southern and northern Brazil

2019 ◽  
Vol 41 (1) ◽  
pp. 83-88 ◽  
Author(s):  
Fabiana Baggio Nerbass ◽  
Edcléia Regina Canzi ◽  
Renata dos Anjos Araujo ◽  
Dyane Corrêa ◽  
Rafaela Gonzaga dos Santos ◽  
...  
Keyword(s):  
Total Sample ◽  
Inorganic Phosphorus ◽  
Cross Sectional Study ◽  
The State ◽  
Cross Sectional ◽  
Significant Difference ◽  
Phosphorus Sources ◽  
Northern Brazil ◽  
The Mean ◽  
Pork Sausages

Abstract Introduction: Hyperphosphatemia is associated with unfavorable outcomes, and the percentage of patients presenting with this condition in hemodialysis (HD) in kidney foundation units in the state of Santa Catarina (SC) is historically higher than that of patients in the state of Tocantins (TO). Objective: To assess the frequency of consumption of the main dietary sources of phosphorus and to compare them between the two states. Methodology: A cross-sectional study was carried out involving 123 patients, 66 of SC and 57 of TO: 52% were men, average age was 46.9 ± 15.7 years, and mean HD time 48 (57-71) months. A food frequency questionnaire (FFQ) with 33 items that are dietary sources of phosphorus was applied. A consumption score was calculated for sources of organic, inorganic, and total phosphorus, and the six-month average of phosphatemia was obtained. Results: The mean phosphatemia of SC patients was higher (6.2 ± 1.5 vs 4.7 ± 1.3 mg/dL, p <0001) than TO patients, as well as the prevalence of hyperphosphatemia (62% vs 28%; p <10001). In the total sample, the foods most frequently consumed were milk and beans. Comparing the frequency of consumption between the two states, a significant difference was found in 17 items. In TO, beef and beans were the foods most frequently consumed, and in SC, fourteen other items of the FFQ (pork, sausages, dairy products, etc.) were the most frequently consumed. Phosphatemia correlated with the frequency of consumption of inorganic phosphorus sources. Conclusion: the frequency of consumption of several items was different between the states, and this explains the differences in phosphatemia between the two regions.

A Study on Bolton Anterior Tooth Size Discrepancies among Different Malocclusion Groups

2013 ◽  
Vol 1 (2) ◽  
pp. 1-4
Author(s):  
AW Ali ◽  
MZ Hossain
Keyword(s):  
Cross Sectional Study ◽  
Normal Group ◽  
Anterior Tooth ◽  
Tooth Size ◽  
Class Iii ◽  
Cross Sectional ◽  
Normal Occlusion ◽  
Significant Difference ◽  
The Mean ◽  
Bangladeshi Population

Aim: To investigate the correlation between anterior tooth size discrepancies among Angle's Class l, ll, lll malocclusions and corresponding normal occlusion, as well as their prevalence in Bangladeshi population. This study would act as a reference for diagnosis, treatment planning and assessment of prognosis in some orthodontic cases. Methods: This cross sectional study was conducted in the Department of Orthodontics & Dentofacial Orthopedics, Dhaka Dental College & Hospital. A total number of 200 subjects were selected in Angle's Class l, ll, lll and corresponding normal group. Each group had 50 subjects with males and females. A chi-square test was performed to statistically compare the prevalence of anterior tooth size discrepancies among Angle's Class l, ll, lll malocclusions and corresponding normal occlusion and two genders. Analysis of variance was used to compare the mean Bolton anterior tooth size ratios as a function of angle classification and gender. Statistical differences were determined at the 95% confidence level (p< 0.05). Results: No significant difference was observed in the mean Bolton anterior ratio between normal group and class-I malocclusion group (p = 0.343). Significant differences were observed between Class-II malocclusion and normal group (p=0.001), and also between Class-III malocclusion and normal group (p = 0.001). Individuals with Angle Class lll and Class ll malocclusions showed significantly greater prevalence of tooth size discrepancy than Class l malocclusion and corresponding normal group. Conclusion: The great diversity and ethnic mix of Bangladeshi population should alert our orthodontist to use Bolton analysis as an important diagnostic tool and become aware of the moderate variations that may be present and treated. It may somehow guide planning of this type of study in future. DOI: http://dx.doi.org/10.3329/bjodfo.v1i2.15982 Ban J Orthod & Dentofac Orthop, April 2011; Vol-1, No.2, 1-4

scholarly journals Oral contraceptive among risk factors for women with ischemic stroke

2021 ◽  
Vol 12 (1) ◽  
pp. 548
Author(s):  
Carla S. PALUDO ◽  
Amanda SACHETTI ◽  
Maiara S. PAIXÃO
Keyword(s):  
Risk Factors ◽  
Ischemic Stroke ◽  
Oral Contraceptive ◽  
Oral Contraceptives ◽  
Contraceptive Use ◽  
Cross Sectional Study ◽  
Mean Value ◽  
Northern Region ◽  
Cross Sectional ◽  
The Mean

Objective: To evaluate the frequency of use of oral contraceptives and other risk factors among women with ischemic stroke seen at a hospital in the northern region of the state of Rio Grande do Sul. Methods: Prospective, cross-sectional study. The population was characterized by patients admitted with a diagnosis of ischemic stroke during a period from March to August 2019 and the sample by female patients found in the population. The data were collected through an individual interview using a questionnaire developed by the researchers and tabulated for further analysis. All analyzes were performed using the statistical program Bioestat 5.0, considering p = 0.05. Results: In the characterization of the sample, an average age of 68.2 years was observed. The occurrence of gender was 52.4% for women. The mean hospital stay was 12.2 ± 8.91 days. Outcome of hospital discharge was 89.1%. The mean value of body mass index was 25 ± 4.89 kg / m², with an average of 27.4 kg / m² in patients who used oral contraceptives and 25.23 kg / m² in patients who did not use oral contraceptives. The sample had a 34.5%incidence of oral contraceptive use. The average age of those who used oral contraceptives was 62.4 years and of the patients who did not use it was 70.3 years. Conclusion: The study showed a high use of oral contraceptives in the sample, with percentage values very close to other factors evaluated, thus showing itself as a probable risk factor for the development of ischemic stroke.

scholarly journals Usefulness of the Non-Contact Tonometry in Out-Patient Screening

2016 ◽  
Vol 15 (2) ◽  
Author(s):  
Satheesh Solomon T Selvin ◽  
Chris Elsa Samson Jacob ◽  
Thomas Kuriakose
Keyword(s):  
Central Corneal Thickness ◽  
Care Center ◽  
Corneal Thickness ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Applanation Tonometry ◽  
Cross Sectional ◽  
Significant Difference ◽  
Iop Measurement ◽  
The Mean

Purpose: Goldmann applanation tonometry (GAT) is considered the gold standard for Intraocular Pressure (IOP) measurement. It has the disadvantages of being a contact device, need for a slit-lamp, non-portability and need of a skilled examiner. Many hospitals are using a Non Contact Tonometry (NCT) as a screening device to save clinician time, however the usefulness is not proved in terms of reliability. This study was aimed to determine the usefulness of the Air-puff tonometer (TONOREF NIDEK II, NIDEK CO., LTD., JAPAN) over a GAT in a tertiary care center. Design: Cross-sectional Study Methods: This was a cross-sectional, non interventional observational study conducted on 224 eyes (right eye) from 224 patients. All patients underwent the IOP measurement with both methods and a central corneal thickness (CCT) measured. The data was analyzed using SPSS 20.0 software. Results: The mean age of the patients was 40.3±11.29 years. There was a statistically significant difference (p<0.001) between the mean NCT and GAT readings which persisted even after correction for central corneal thickness. The correlation between NCT and GAT using Pearson’s correlation coefficient was strong irrespective of the corrections for their corneal thickness (r = 0.751 and 0.718 for uncorrected and corrected values respectively). The correlation of the individual clinicians for the readings varied from moderate to strong. The ROC curve showed the best sensitivity and specificity to occur at around 13 to 14 mmHg. Conclusion: NCT seems to overestimate the IOP at low ranges as compared to the GAT and underestimate at higher ranges. The crossover of the values is seen between 12 to 13 mmHg.  The clinician should do an individualized analysis of his/her GAT measurements to the readings of the NCT machine at the clinic to obtain clinician specific nomogram. 

scholarly journals Facteurs Épidémiologiques et Pronostiques Associés Aux Étiologies Des Hémorragies Digestives Hautes au CHU Campus de Lomé

2021 ◽  
Vol 17 (34) ◽  
pp. 44
Author(s):  
Aklesso Bagny ◽  
Lidawu Roland-Moise Kogoe ◽  
Laconi Yeba Kaaga ◽  
Late Mawuli Lawson-Ananissoh ◽  
Debehoma Redah ◽  
...  
Keyword(s):  
Teaching Hospital ◽  
Cross Sectional Study ◽  
Mean Value ◽  
Peptic Ulcers ◽  
Gi Bleeding ◽  
Cross Sectional ◽  
Hémorragies Digestives ◽  
Upper Gi Bleeding ◽  
Upper Gi ◽  
The Mean

Objectif : Décrire les aspects épidémiologique, clinique et pronostique associés aux étiologies des hémorragies digestives hautes au CHU Campus de Lomé Patients et méthode: Etude transversale à collecte rétrospective, à visée descriptive et analytique menée du 1er Janvier 2014 au 31 Décembre 2019. Le seuil de significativité était retenu pour p<0,05. Résultats: Deux cent cinquante et un patients avaient été inclus. L’hémorragie était d’origine hypertensive portale chez 69 patients (27,71%) ; ulcéreuse gastro-duodénale chez 100 patients (39,84%). Chez 25 patients (9,96%), la fibroscopie oesogastroduodénale était normale. Une rupture de varices oesophagiennes était retrouvée chez 98,55% des patients présentant une hypertension portale. Les ulcères gastroduodénaux représentaient 54,94% des hémorragies digestives hautes d’origine non hypertensive portale. La valeur moyenne du score de Rockall était de 4(±1) chez les patients présentant une hémorragie d’origine hypertensive et de 3(±1) chez les patients avec hémorragie non hypertensive portale (p<0,001). La valeur moyenne du score de Glasgow-Blatchford était de 10(±3) chez les patients présentant une hémorragie d’origine hypertensive et 9(±3) chez les patients avec hémorragie digestive haute d’origine non hypertensive (p<0,001). La récidive hémorragique et le décès étaient survenus chez les patients présentant un saignement d’origine hypertensive portale dans respectivement 54,84% (p<0,001) et 71,42% (p<0,001). Conclusion: Les lésions inflammatoires aiguës et chroniques représentent la première étiologie des hémorragies digestives hautes dans le service d’Hépato-gastroentérologie du CHU Campus. Ces hémorragies sont associées à la prise de médicaments gastrotoxiques et à un moindre risque de récidive hémorragique et de décès. Objective: To describe epidemiological et prognostic outcomes associated with etiologies upper gastrointestinal bleeding in Campus Teaching Hospital of Lome Patients and method: Cross-sectional study with retrospective collection, descriptive and analytical aim carried out from January 1, 2014 to December 31, 2019. Results: Two hundred and one patients were included. The hemorrhage was of portal hypertensive origin in 69 patients (27.71%); peptic ulcer in 100 patients (39.84%). In 25 patients (9.96%), the oesogastroduodenal fibroscopy was normal. Ruptured esophageal varices were found in 98.55% of patients with portal hypertension. Peptic ulcers accounted for 54.94% of upper GI bleeding of non-portal hypertensive origin. The mean value of the Rockall score was 4(±1) in patients with hemorrhage of hypertensive origin and 3(±1) in patients with non-portal hypertensive hemorrhage (p<0.001). The mean Glasgow-Blatchford score was 10(±3) in patients with hemorrhage of hypertensive origin and 9(±3) in patients with upper GI hemorrhage of nonhypertensive origin (p<0.001). Hemorrhagic recurrence and death occurred in patients with bleeding of hypertensive origin in 54.84% (p<0.001) and 71.42% (p<0.001) respectively. Conclusion: Acute and chronic inflammatory lesions represent the first etiology of upper GI bleeding in the Gastroenterology Department of the Campus Teaching Hospital of Lome. These hemorrhages are associated with the use of gastrotoxic drugs and with a lower risk of recurrence of hemorrhage and death.

scholarly journals Prevalence and predictors of dyslipidemia on HAART and HAART naive HIV positive clients attending Debre Tabor Hospital, Debre Tabor, Ethiopia

2021 ◽  
Author(s):  
Anemut Tilahun Mulu ◽  
Getachew Yideg Yitbarek ◽  
Fitalew Tadele Admasu ◽  
Chalachew Yenew Denekew ◽  
Biruk Demissie Melese
Keyword(s):  
Venous Blood ◽  
Cross Sectional Study ◽  
Mean Value ◽  
Anthropometric Measurement ◽  
Hiv Positive ◽  
Cross Sectional ◽  
Immunodeficiency Virus ◽  
Debre Tabor ◽  
The Mean ◽  
Cd4 Cell

Abstract Background: HAART has been reported to be associated with a number of side effects in human immunodeficiency virus patients among which dyslipidemia is a common metabolic disorder. Methods: A facility based comparative cross-sectional study among 228 HIV positive persons was conducted from July to August 2020. Socio-demographic and clinical data were collected using structured questionnaires. Fasting venous blood sample was drawn for Lipid profiles and CD4 cell determination. Anthropometric measurement was done. Data was analyzed using SPSS version 22 for windows. Result: A total of 228 HIV patients were enrolled in the study. Prevalence of dyslipidemia in HAART naive and on HAART HIV positive persons was 61(53.5%) and 84 (73.7%), respectively. The prevalence of TC≥200 mg/dl was 50% and 30%; HLD-c<40 mg/dl was 43.8% and 36%; LDL-c≥130mg/dl was 48.3% and 28.1%; and TG≥150 mg/dl 59.6% and 39% among on HAART and HAART naïve, respectively. Age greater than 40 years (AOR = 3.27, 95% C.I: 1.47 - 7.25), blood pressure ≥ 140/90 (AOR = 16.13, 95% C.I: 5.81 - 44.75), being on HAART (AOR = 2.73, 95 % C.I: 1.35 - 5.53) and body mass index > 25kg/m2 (AOR = 1.92, 95 % C.I: 1.20 - 4.81) were identified as determinants of dyslipidemia. Conclusion: The mean value of lipid profile was significantly higher among HIV positive clients on HAART as compared to those HAART naïve HIV positive clients.

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