scholarly journals Frequency of BCG vaccination in children with tuberculous meningitis at Liaquat University Hospital Hyderabad.

2019 ◽  
Vol 26 (10) ◽  
pp. 1665-1671
Author(s):  
Shamaeel ◽  
Farzana Shiakh ◽  
Ghulam Shabbir Laghari ◽  
Yasmeen Memon
Keyword(s):  
Tuberculous Meningitis ◽  
Protective Efficacy ◽  
University Hospital ◽  
Axillary Temperature ◽  
Cross Sectional ◽  
Bcg Vaccination ◽  
History Of ◽  
Continued Use ◽  
Study Setting ◽  
Csf Findings

Objectives: To determine the frequency of BCG vaccination in children with tuberculous meningitis of age 01 to 12 years at Liaquat University Hospital Hyderabad. Study Design: Cross sectional descriptive study. Setting: Department of Pediatrics, Liaquat University Hospital, Jamshoro / Hyderabad. Period: Six months from 20-08-2016 to 20-02-2017. Material and Methods: A total of 189 children with history of fever (axillary temperature >37.2°C) for ≥14 days duration with presentation, CT scan and CSF findings consistent with tuberculous meningitis were selected in this study. The data was collected on pre-structured proforma (attached). Results: There were 86(45.5%) male and 103(54.5%) female. Frequency of BCG vaccination in children with tuberculosis meningitis was found in 130(68.78%) cases. Conclusion: Our results show effectiveness of BCG vaccine in preventing TBM. Regardless of the protective efficacy of BCG in preventing pulmonary tuberculosis, in areas in which tuberculosis affects a significant percentage of the population, continued use of BCG may be warranted to prevent tuberculous meningitis.

scholarly journals METHOTREXATE;

2017 ◽  
Vol 24 (04) ◽  
pp. 607-611
Author(s):  
Muhammad Yasir Qureshi ◽  
Zaheer Hussain Memon ◽  
Ishrat Bibi
Keyword(s):  
Plaque Psoriasis ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Cross Sectional ◽  
Dermatology Department ◽  
Pasi Score ◽  
History Of ◽  
Duration Of Disease ◽  
Study Setting

Objectives: To determine the efficacy of methotrexate as a treatment option forplaque psoriasis. Study Design: Cross sectional study. Setting: Dermatology Department, ofLiaquat University hospital Hyderabad. Period: 6 month duration from January 2016 to June2016. Material & Methods: All the cases more than 20 years of the age having severe-tomoderatechronic plaque psoriasis were selected in the study. All the patients were underwentcomplete medical history and clinical examination. All the patients with history of severecomorbidities were not included. All the patients were underwent oral methotrexate treatment.All the information as: disease duration, involved site and plaque size was recorded. Efficacywas assessed according to PASI score on starting and after 12 weeks. Results: Patients’ meanage was 40.73 years. Male were found in the majority 75.50%, while 24.50 % were female. Inthis study mean duration of disease was 7.38 + 3.46 months and mean duration of plaque sizewas 6.63+ 2.07. Commonest site involved in psoriasis was scalp+elbow seen in 27(55.1%).Psoriasis show significant good outcome after treatment of methotrexate, 9 patients did notcompeted their treatment in remaining 40 cases starting PASI score was 11.97+1.40 and after12 weeks treatment significantly decreased as 6.48+2.45 and mean of clearance time was8.10+2.02 weeks. Conclusion: Methotrexate showed significant satisfactory results in thetherapy required for plaque psoriasis as well as enhanced quality of life.

Malaria among migrants in a university hospital in Colombia during 2018: A case series

2020 ◽  
pp. 004947552098130
Author(s):  
Fabián R Carreño-Almánzar ◽  
Adán Coronado-Galán ◽  
Sonia A Cala-Gómez ◽  
Agustín Vega-Vera
Keyword(s):  
Latin American ◽  
Previous History ◽  
Case Series ◽  
Cross Sectional Study ◽  
Imported Malaria ◽  
University Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
History Of ◽  
Clinical Profiles

Imported malaria has increased in Colombia since 2015 and has been attributed to migrants coming from Venezuela. We present a series of malaria cases, nested in a retrospective cross-sectional study between 2017 and 2018, aimed at calculating the prevalence of medical diseases among immigrants in a University Hospital in Colombia. Among 154 immigrants admitted for medical causes between 2017 and 2018, 8 were diagnosed with malaria, all due to Plasmodium vivax. Of these, seven had uncomplicated malaria, five had a previous history of malaria, one was critically ill, but none died. We highlight that, similar to other case series of imported malaria, Latin American migrants were young, with similar clinical profiles, having a low proportion of severe cases, and P. vivax was the most frequent cause.

scholarly journals Vulnerabilities of children admitted to a pediatric inpatient care unit

2014 ◽  
Vol 32 (4) ◽  
pp. 367-373 ◽  
Author(s):  
Larissa Natacha de Oliveira ◽  
Márcia Koja Breigeiron ◽  
Sofia Hallmann ◽  
Maria Carolina Witkowski
Keyword(s):  
Illicit Drugs ◽  
Total Sample ◽  
University Hospital ◽  
Cross Sectional ◽  
Health History ◽  
History Of ◽  
Pediatric Inpatient ◽  
Inpatient Units ◽  
Child Caregiver ◽  
Networks Of Support

OBJECTIVE: To identify the vulnerabilities of children admitted to a pediatric inpatient unit of a university hospital.METHODS: Cross-sectional, descriptive study from April to September 2013 with36 children aged 30 days to 12 years old, admitted to medical-surgical pediatric inpatient units of a university hospital and their caregivers. Data concerning sociocultural, socioeconomic and clinical context of children and their families were collected by interview with the child caregiver and from patients, records, and analyzed by descriptive statistics.RESULTS: Of the total sample, 97.1% (n=132) of children had at least one type of vulnerability, the majority related to the caregiver's level of education, followed by caregiver's financial situation, health history of the child, caregiver's family situation, use of alcohol, tobacco, and illicit drugs by the caregiver, family's living conditions, caregiver's schooling, and bonding between the caregiver and the child. Only 2.9% (n=4) of the children did not show any criteria to be classified in a category of vulnerability.CONCLUSIONS: Most children were classified has having a social vulnerability. It is imperative to create networks of support between the hospital and the primary healthcare service to promote healthcare practices directed to the needs of the child and family.

scholarly journals Recurrent Miscarriage and Consanguinity among Omani Women– A Cross Sectional Study

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Fatma Al Hoqani ◽  
Wadha Al Ghafri ◽  
Saneya El tayeb ◽  
Yahya Al Farsi ◽  
Vaidyanathan Gowri
Keyword(s):  
Recurrent Miscarriage ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Control Group ◽  
P Value ◽  
Cross Sectional ◽  
Recurrent Miscarriages ◽  
Sultan Qaboos University ◽  
Chi Squared ◽  
History Of

Objective: to determine the prevalence of explained and unexplained recurrent miscarriages (RM) and to find out if there is a significant relationship between recurrent miscarriages and consanguinity. Methods: A cross sectional in which the cases group included all women with RM attending the outpatient clinic at Sultan Qaboos University Hospital from July 2006 to April 2012 and the controls group included women with no history of RM after matching them with cases for age (case to control ratio was 1:1). The main outcome measures were the prevalence of consanguinity in women with or without recurrent miscarriages. Results: During study period a total of 290 women with RM were seen. Of which, 150 (51.7%) women had unexplained RM. Control group with no history of RM were 300 women. Consanguinity rate among cases (49.5%) %) was less than the controls (52.7 %%). Both first cousin and second cousin marriages were more common in the controls than the cases and it was not statistically significant (p value 0.476, chi squared test). Conclusion: In this study we found that more than half of RM cases were unexplained and there was no significant association between RM and consanguinity.

scholarly journals OVARIAN MALIGNANCY

2018 ◽  
Vol 25 (02) ◽  
pp. 237-241
Author(s):  
Shabana Rafiq ◽  
Razia Bibi ◽  
Samina Ashraf
Keyword(s):  
Cross Sectional Study ◽  
Reproductive Age ◽  
Ovarian Malignancy ◽  
Ovarian Mass ◽  
Sectional Study ◽  
Women Of Reproductive Age ◽  
Cross Sectional ◽  
Increased Risk ◽  
History Of ◽  
Study Setting

Objectives: To determine the frequency of ovarian malignancy in women ofreproductive age presenting with ovarian mass and to determine frequency of factors leadingto ovarian malignancy. Study Design: Cross sectional study. Setting: Department of Obstetrics& Gynaecology, Lady Wallington Hospital, Lahore. Period with Dates: From 05.11.11 to26.06.12. Results: The result of our study reveals majority of the patients between 21-30 yearsi.e. 45.88%(n=39), common age was 24.21+3.76 years, 43.53%(n=37) were nulliparous (inmajority), while frequency of ovarian malignancy in women of reproductive age presenting withovarian mass was recorded in 14.11%(n=12) while frequency of factors leading to ovarianmalignancy was 91.67%(n=11) patients were nulliparous while family history of ovarianmalignancy was in 8.33%(n=1) patients. Conclusions: The frequency of ovarian malignancy ishigher among reproductive age females with increased risk of nulliparity.

scholarly journals Hepatitis C in pregnancy: an observational study highlighting its association with maternal parameters

2019 ◽  
Vol 8 (1) ◽  
pp. 344
Author(s):  
Bushra . ◽  
Ambreen Ghori ◽  
Azra Ahmed ◽  
Najma Dalwani ◽  
Mushtaque Ali Shah ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Previous History ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Prior History ◽  
Singleton Pregnancy ◽  
Cross Sectional ◽  
History Of

Background: Pregnancy is a very crucial time in a woman’s life. In this period of time, not only multiple physiological alterations effect the usual health status but also makes women more vulnerable to contract infection and face negative sequalae. Hepatitis C, a blood borne viral infection serve the similar fate when encountered by pregnant ladies. This study is based on exploring the prevalence of the Hepatitis C virus seropositivity among pregnant population. Moreover, we also evaluated the major risk factors leading to the infection in these mothers. Besides this, infected mothers were studied for their pregnancy outcomes.Methods: In this study 114 pregnant females were observed for this cross-sectional study. It was conducted in Gynecology Unit- 1, Liaquat University Hospital Hyderabad, for the period of January 2017 to July 2017. Chi square test was applied for statistical analysis on SPSS version 16. The criteria for enrollment in the study was set to be a pregnant lady belonging to age group 20-35 years; having singleton pregnancy; was a booked case at the hospital with compliant to antenatal follow ups; admitted to the labor room for delivery. All the non-pregnant ladies, whom had co morbid conditions such as hypertension or diabetes or had infected with hepatitis B or D were excluded from the study. Furthermore, pregnant ladies with multiple gestion or those who were either diagnosed of hepatitis C prior to conceive or had a previous history of hepatitis C were also excluded.Results: Present study revealed that out of 114, 10(8.8%) pregnant ladies were found seropositive for Hepatitis C virus. Prior history for transfusion of blood was the Foremost risk factor discovered, with 60.5% women reported this. History of surgery was the 2nd commonest factor and 43.9% had this in their medical records. On the other hand, only 8.8% women gave the history for previous evacuation. While observing pregnancy outcomes, we found 48.2% neonates had low birth weight, 41.2% were born preterm and 21.1% had low APGAR score.Conclusions: In a nutshell hepatitis c is prevalent in the pregnant population of this region and showing its effects in the form of compromised pregnancies. History of blood transfusion and previous surgery were found to be chief risk factors in the study.

scholarly journals HEPATITIS “C”

2016 ◽  
Vol 23 (09) ◽  
Author(s):  
Muhammad Iqbal ◽  
Adnan Ahmed ◽  
Muhammad Rafique Hingoro
Keyword(s):  
Hepatitis C ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Grade 3 ◽  
Chronic Hcv ◽  
Study Setting

Objectives: To determine incidence of steatosis in non-responder casesof chronic HCV. Study Design: Cross-sectional study. Setting: Tertiary Care Sanatorium inMedicine Department of LIAQUAT University Hospital Hyderabad/Jamshoro. Period: 26-9-2011to 25 August 2012. Material & Methods: Total 144 non-responders cases of Hepatitis C wereintegrated. Both gender, age 18 to 50 yrs, chronic HCV non-responder cases as well as cases fitfor hepatic biopsy were integrated in study. Grading of Inflammation was carried out as indicatedby histopathological measures. Results: Mean age was 48.5 + 5.2years. Uppermost prevalenceof chronic HCV disease was 65(45.13%) at 41 to 50 years age interval whereas 42(29.1%) caseswere noticed in 31 to 40 yrs age group and 25(17.3%) cases were observed in 20 to 30 yearsof young age group. In this study hepatic steatosis occurrence was observed in 103 (71.5%)cases and these were categories as: grade 1, grade 2, grade 3, as (<33%) 45/103(43.68%), (33to 66%) 35/103(33.98%), (>66%) 23/103(22.33%) respectively. Conclusion: Hepatic steatosisis a important risk factor the cases of HCV to decreased response to antiviral therapy and forprogression toward fibrosis as observed in cases related to metabolic steatosis.

scholarly journals Estimation of cerebrospinal fluid cortisol level in tuberculous meningitis

2015 ◽  
Vol 06 (04) ◽  
pp. 541-544 ◽  
Author(s):  
Rohan R. Mahale ◽  
Anish Mehta ◽  
Sudhir Uchil
Keyword(s):  
Cerebrospinal Fluid ◽  
Cortisol Level ◽  
Tuberculous Meningitis ◽  
Morbidity And Mortality ◽  
Cns Involvement ◽  
Tubercular Meningitis ◽  
Cross Sectional ◽  
Delay In Diagnosis ◽  
Appropriate Treatment ◽  
Csf Findings

ABSTRACT Background: Central nervous system (CNS) involvement in tuberculosis is around 5–10%. Of the various manifestations of CNS tuberculosis, meningitis is the most common (70–80%). Delay in diagnosis and treatment results in significant morbidity and mortality. Objective: To study the cerebrospinal fluid (CSF) cortisol levels in tubercular meningitis and compare the levels with controls. Methods: Cross-sectional, prospective, observational, hospital-based study done in 20 patients of tubercular meningitis, 20 patients of aseptic meningitis (AM) and 25 control subjects without any preexisting neurological disorders who have undergone lumbar puncture for spinal anesthesia. Results: Cortisol was detected in all 40 CSF samples of patients (100%). Mean CSF cortisol level was 8.82, 3.47 and 1.05 in tubercular meningitis, AM and controls, respectively. Mean CSF cortisol level in tubercular meningitis was significantly higher as compared to AM and controls (P < 0.0001). Conclusion: Cortisol level estimation in CSF is one of the rapid, relatively inexpensive diagnostic markers in early identification of tubercular meningitis along with CSF findings of elevated proteins, hypoglycorrhachia and lymphocytic pleocytosis. This aids in earlier institution of appropriate treatment and thereby decreasing morbidity and mortality. This is the first study on the estimation of CSF cortisol level in tuberculous meningitis.

scholarly journals Prevalence and reasons of use of different psychoactive substances among prisoners at Malir Prison, Karachi.

2020 ◽  
Vol 27 (07) ◽  
pp. 1488-1492
Author(s):  
Muhammad Ilyas Jat ◽  
Muhammad Tarique Arain ◽  
Saima Qureshi ◽  
Kheenpal Das ◽  
Anum Haider
Keyword(s):  
Substance Use ◽  
Peer Pressure ◽  
Cross Sectional Study ◽  
Psychoactive Substance ◽  
Psychoactive Substances ◽  
Ethical Considerations ◽  
Cross Sectional ◽  
History Of ◽  
Male Prisoners ◽  
Study Setting

The use psychoactive substances are on the rise in general population and even seen more among those who are involved in criminal activities. There are many reasons for such irrational use of psychoactive substances. Objectives: To determine the prevalence and reasons of use of different psychoactive substances among prisoners at Malir prison, Karachi. Study Design: Descriptive Cross-Sectional study. Setting: Malir prison, Karachi. Period: 22nd April 2019 to 26th May 2019. Material & Methods: This study was conducted at district Malir prison, Karachi. All the cases who were imprisoned due to any reason and had history of psychoactive substance use were enrolled. Thorough history and examination was carried out. Ethical considerations were taken as per international guidelines. Results: Among all 490 male prisoners who used to take different type of psychoactive substance, majority were of age ranges of 21 to 35 years and 55% were married while 44% were single and 1% were divorced or separated. Out of 490 cases 453 (92%) were using different substances thorough routes other than injections while 37 (8%) were injection users. Majority of prisoners 252 (52%) were using Heroin while 86 (17%) were using Crystals, 74 (15%) Cannabis, 37 (8%) Synthetic substances, 24 (5%) Ice, 6 (1%) Opioid and 11 (2%) were using some other type of substance. The most common reason of substance use was peer pressure followed by fun and frustration. Conclusion: Substance use prevalence is high in prison. Existing services for the management of drug dependence are not meeting the global standard of evidence based comprehensive drug treatment and rehabilitation.

scholarly journals ASSOCIATION OF SEROPOSITIVITY FOR CMV IGM AND IGG WITH ADVERSE PREGNANCY OUTCOME

2021 ◽  
Vol 71 (3) ◽  
pp. 831-35
Author(s):  
Ambreen Amna ◽  
Farkhunda Nadeem ◽  
Amin Fahim ◽  
Altaf Hussian Jatoi ◽  
Kanwal Abbas ◽  
...  
Keyword(s):  
Pregnancy Outcome ◽  
Adverse Pregnancy Outcome ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
University Hospital ◽  
Igg Antibodies ◽  
Cross Sectional ◽  
History Of ◽  
Adverse Pregnancy ◽  
Reproductive Age Group

Objective: To find out the prevalence of antibodies against cytomegalovirus and their association with adverse pregnancy outcome in women, at Isra University Hospital Hyderabad. Study Design: Cross-sectional study. Place and Duration of Study: Department of Gynaecology & Obstetrics, Isra University Hospital (IUH) Hyderabad, from Jan to Jun 2018. Methodology: Cytomegalovirus IgM and IgG antibodies in 305 women of reproductive age group were measured using the Enzyme Linked Fluorescent Assaysystem kit. Results: The combined positivity of anti cytomegalovirus IgG and IgM antibodies was 93 (30.40%). About 37 (37.37%) and 28 (34.14%) women were found to be seropositive for cytomegalovirus antibodies who had history of spontaneous miscarriage and recurrent miscarriages respectively. Conclusion: Higher association of seropositivity for cytomegalovirus IgM and IgG with bad obstetrical history and low economy was found.

Sign in / Sign up

Export Citation Format

Share Document