scholarly journals Accuracy of FAST (Focused Abdominal Sonography in Trauma) scan in diagnosis of significant abdominal trauma using CT abdomen as gold standard.

2020 ◽  
Vol 27 (10) ◽  
pp. 2067-2071
Author(s):  
Hina Hanif ◽  
Tahira Bibi ◽  
Riffat Raja ◽  
Sara Malik
Keyword(s):  
Abdominal Trauma ◽  
Gold Standard ◽  
Research Work ◽  
Cross Sectional Study ◽  
High Rate ◽  
Free Fluid ◽  
Cross Sectional ◽  
Abdominal Sonography ◽  
Male Patients ◽  
Study Setting

Objectives: The aim of this research work is to find out the precision of FAST scan in detection of the significant abdominal trauma with the utilization of the CT abdomen considering it as a gold standard. Study Design: Cross Sectional study. Setting: Department of Radiology and Department of Emergency in Holy Family Hospital, Rawalpindi. Period: Six months from March, 2019 to September 2019. Material & Methods: Total 120 patients of both genders having age from 16 to 65 years who were presented in the Department of Trauma emergency. Both were the participants of this research work. We carried out CT of abdomen and FAST scan for every patient. We also calculated the sensitivity, PPV, NPV, specificity and overall accuracy rate of the FAST scan. Results: There were 80.80% (n: 97) male patients and 19.20% (n: 23) patients were females. We found 28.30% (n: 34) patients as positive in FAST scan and 22.50% (n: 27) patients as positive on CT of abdomen. FAST scan’s accuracy, NPV, PPV, sensitivity and specificity were present as 84.20%, 93%, 61.80%, 77.8% and 86% respectively. Conclusion: FAST scan permits the identification of the free fluid gathered in various regions of the abdomen cavity because of the BAT with high rate of sensitivity, PPV, NPV and specificity.

scholarly journals TO DETERMINE THE ADVANTAGE OF SNODGRASS REPAIR OF CONGENITAL HYPOSPADIAS AT DIFFERENT LEVEL OF PENILE SHAFT.

2019 ◽  
Vol 26 (07) ◽  
pp. 1027-1031
Author(s):  
Shafaatullah . ◽  
Sadaf Iqbal ◽  
Bilal Suria
Keyword(s):  
Hormonal Therapy ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Common Complication ◽  
Sectional Study ◽  
Penile Shaft ◽  
Cross Sectional ◽  
Good Cosmetic ◽  
Male Patients ◽  
Study Setting

Introduction: Hypospadias is a congenital defect with various presentations. It is diagnosed clinically. Hormonal therapy can be used but is not curative. The Snodgrass intervention is the better one to get result oriented outcomes. Objectives: To find out the advantages of Snodgrass repair in distal as well as proximal types of hypospadias. Study Design: Cross sectional study. Setting: Baqai university hospital Karachi. Period: January 2015 to December 2017. Material and Method: Total 40 male patients were included in this study. They were admitted through OPD. Age of patients was from 4 years to 22 years. Patients were prepared and Snodgrass repair was done to all patients. Results: In our study, of 40, 19 (47.5%) patients presented between age 04 to 10 years. Most common Subcoronal type was found in 16 (40%). Catheter blockage was in 4 (10%) patients that was a common complication in our study. Conclusion: To sum up, Snodgrass method is the good one with good cosmetic results and least complication rate. 

scholarly journals HYPONATREMIA;

2017 ◽  
Vol 24 (11) ◽  
pp. 1647-1651
Author(s):  
Riaz Ahmed Javid ◽  
Ayesha Ghafoor ◽  
Ifrah Ahmed
Keyword(s):  
Hepatic Encephalopathy ◽  
Cross Sectional Study ◽  
P Value ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Male And Female ◽  
Male Patients ◽  
The Difference ◽  
Study Setting

Objectives: To find out the frequency of hyponatremia in cases of hepaticencephalopathy. Study Design: Cross-sectional study. Setting: Department of Medicine DGKhan Hospital, DG Khan. Period: July 2016 to December 2016. Material and Methods: Total80 patients with hepatic encephalopathy either male or female were selected for this study.Hyponatremia was assessed in these selected patients. Results: Mean age of the patientswas 38.34 ± 11.140 years. Hyponatremia was found in 31 (39%) patients. Hyponatremia wasnoted in 13 (41.94%) patients of age group 18-36 years and 18 (36.73%) patients of age group37-55 years. Statistically insignificant association of hyponatremia with age was seen with pvalue 0.6467. Hyponatremia was found in 21 (40.38%) male patients and 10 (35.71%) femalepatients. But the difference of frequency of hyponatremia between male and female patients wasstatistically insignificant with p value 0.8109. Conclusion: Results of this study showed a higherpercentage of hyponatremia in patients with HE. Male were more victim of HE as compared tofemale but insignificant association of hyponatremia with gender is noted. Findings of presentstudy showed that there is insignificant association of hyponatremia with grade of HE, socioeconomicstatus, area of residence and age.

scholarly journals ASSESSMENT OF EFFECTS ON HEMATOLOGICAL PARAMETERS AFTER INTERFERON AND RIBAVIRIN THERAPY AMONG HEPATITIS C PATIENTS IN KARACHI.

2019 ◽  
Vol 26 (07) ◽  
pp. 1162-1166
Author(s):  
Zubia Zia ◽  
Naim ul Hasan Naqvi ◽  
Ayaz Mustafa ◽  
Muzammil Hussain ◽  
Aysha Zia ◽  
...  
Keyword(s):  
Hepatitis C ◽  
Hematological Parameters ◽  
Cross Sectional Study ◽  
Current Status ◽  
Hcv Rna ◽  
Cross Sectional ◽  
Period 2 ◽  
Effect Of Therapy ◽  
Male Patients ◽  
Study Setting

Objectives: This study aims to evaluate the hematological abnormalities treated with interferon and ribavirin therapy in hepatitis C patients of Pakistan. Study Design: Descriptive cross sectional study. Setting Gastroenterology and Hepatology Department of JPMC, Karachi, Pakistan. Period: 2 years. Materials and Methods: All the patients with positive HCV RNA test were enrolled in the study and their HB, WBC`s and platelets level were assessed. Standard treatment (interferon and ribavirin) against HCV were started. Then after 6 months of therapy, their levels of HB, WBC`s and platelets were again evaluated to examine the current status. Results: 88 Cases of HCV were enrolled in the study, of which 52(59%) were females patients and 36 (41%) were male patients. 33(37.5%) patients were those who had age below than 40 years while 55(62.5%) patients were those who had above 40 years age. In these 88 patients 49(55.68%) patients were those who respond toward the therapy and 39(44.31%) patients were those who did not respond toward the therapy. Only 2(2.27%) patients from Non-Responder groups was found with increase WBC’S count, while 17% patient of both groups in case of hemoglobin and 19.3% Patients of both group in case of platelets was found with decreased level after treatment. Conclusion: Interferon plus ribavirin therapy induces anemia due to decreasing hemoglobin level, as well as increases the WBC’S count in case of not responding the therapy and decrease platelet counts have been observed as side effect of therapy.

scholarly journals Frequency and analysis of acute kitchen burn injuries at Allied Hospital, Faisalabad, Pakistan.

2021 ◽  
Vol 28 (09) ◽  
pp. 1297-1301
Author(s):  
Qamar Mehboob ◽  
Waqar Arif ◽  
Sana Arif
Keyword(s):  
Research Work ◽  
Cross Sectional Study ◽  
Burn Injuries ◽  
Detailed Knowledge ◽  
Cross Sectional ◽  
Great Insight ◽  
Medical University ◽  
Study Setting ◽  
Surgery Center ◽  
Insight Into

Objective: To describe the frequency and outcomes of acute kitchen burn patients who were admitted to the burn center. Study Design: Cross Sectional study. Setting: Allied Burn & Reconstructive Surgery Center, Faisalabad Medical University. Period:  August 2019 to August 2020. Material & Methods: A total of 566 cases were registered. In 293 cases, accident took place in kitchen, 153 cases occurred in home settings, 51 cases occurred at workplace and other 27 cases were in industry. 42 cases were reported at other different places. Results: A total of 566 burn cases occurring at different places including kitchen, home settings, workplace, industry and others, were included in the study. In 293 cases (51.766%) accidents took place in kitchen. Other 153 cases (27.03%) occurred in home settings. 51 cases (0.9%) occurred at workplace, 27 cases (0.45%) were in industry and 42 other cases (19.845%) were in different places.  In 2019, total 172 cases were reported. Out of which 113 (65.7%) were males and 59 (34.3%) were females. In 2020, total 394 cases were reported. Out of which 237 (60.15%) were males and 157(39.85%) were females. All ages and both sexes were included. Our results showed that maximum accidents (51.766%) took place in kitchen. Males (61.84%) were affected more than females (38.16%). Regarding age, the group of children (˃10) was most to be effected (49%). Overall statistical analysis for patients was p ˂ 0.046, df =4, 95% CI. Conclusion: Combined with the previous knowledge, our research work provided great insight into the risk factors and detailed knowledge of burn injuries at different levels especially at home kitchen level.

scholarly journals Positive predictive value (PPV) of computed tomography in diagnosing wilms’ tumor using histopathology as gold standard.

2019 ◽  
Vol 26 (10) ◽  
pp. 1755-1759
Author(s):  
Mumtaz Rasool ◽  
Mudassar Saeed Pansota ◽  
Fariha Mumtaz ◽  
Muhammad Shahzad Saleem ◽  
Shafqat Ali Tabassum
Keyword(s):  
Positive Predictive Value ◽  
Ct Scan ◽  
Predictive Value ◽  
Gold Standard ◽  
Wilms Tumor ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Recurrent Tumour ◽  
Increased Risk ◽  
Study Setting

CT can also accurately identify vascular invasion that will impact surgical approach along with identification of the preoperative parameters associated with increased risk of intraoperative Wilms’ tumor spill. Objectives: To determine positive predictive value of CT scan in diagnosing wilm’s tumour, taking histopathology as gold standard. Study Design: Descriptive, cross sectional study. Setting: Department of Urology & Renal Transplantation Centre, Bahawal Vitoria Hospital, Bahawalpur. Period: From July 2017 to June 2018. Materials & Methods: A total of 81 patients with suspected wilm’s tumour on ultrasonography of age 1-12 years of either gender were included. Patients with recurrent tumour and undergoing pre-op chemotherapy were excluded. All the patients were then underwent CT scan and looked for presence or absence of wilm’s tumour. The results were compared with histopathology. Results: Mean age was 5.23 ± 3.28 years. Majority of the patients 56 (69.14%) were between 1 to 6 years of age. Out of these 81 patients, 61 (75.31%) were female and 20 (24.69%) were males with female to male ratio of 2.9:1. CT scan supported the diagnosis of wilm’s tumour in all 46 patients. Histopathology confirmed wilm’s tumour in 41 (true positive) cases where as 05 (False Positive) had no wilm’s tumour on histopathology. Positive predictive value of CT scan in diagnosing wilm’s tumour, taking histopathology as gold standard was 89.13%. Conclusion: This study concluded that positive predictive value of CT scan in diagnosing wilm’s tumour is quite high.

STUDY ON THRIVE SCORE IN THE PROGNOSIS OF ISCHEMIC STROKE

2017 ◽  
pp. 22-24
Author(s):  
Thi Thao Nhi Tran ◽  
Dinh Toan Nguyen
Keyword(s):  
Ischemic Stroke ◽  
Clinical Outcome ◽  
Regression Models ◽  
Cross Sectional Study ◽  
High Rate ◽  
Vascular Events ◽  
Cross Sectional ◽  
Key Words Ischemic Stroke ◽  
Outcome Mortality ◽  
Better Than

Background and Purpose: Stroke is the second cause of mortality and the leading cause of disability. Using the clinical scale to predict the outcome of the patient play an important role in clinical practice. The Totaled Health Risks in Vascular Events (THRIVE) score has shown broad utility, allowing prediction of clinical outcome and death. Methods: A cross-sectional study conducting on 102 patients with acute ischemic stroke using THRIVE score. The outcome of patient was assessed by mRankin in the day of 30 after stroke. Statistic analysis using SPSS 15.0. Results: There was 60.4% patient in the group with THRIVE score 0 – 2 points having a good outcome (mRS 0 - 2), patient group with THRIVE score 6 - 9 having a high rate of bad outcome and mortality. Having a positive correlation between THRIVE score on admission and mRankin score at the day 30 after stroke with r = 0.712. THRIVE score strongly predicts clinical outcome with ROC-AUC was 0.814 (95% CI 0.735 - 0.893, p<0.001), Se 69%, Sp 84% and the cut-off was 2. THRIVE score strongly predicts mortality with ROC-AUC was 0.856 (95% CI 0.756 - 0.956, p<0.01), Se 86%, Sp 77% and the cut-off was 3. Analysis of prognostic factors by multivariate regression models showed that THRIVE score was only independent prognostic factor for the outcome of post stroke patients. Conclusions: The THRIVE score is a simple-to-use tool to predict clinical outcome, mortality in patients with ischemic stroke. Despite its simplicity, the THRIVE score performs better than several other outcome prediction tools. Key words: Ischemic stroke, THRIVE, prognosis, outcome, mortality

scholarly journals Evaluation of SARS-CoV-2 antigen-based rapid diagnostic kits in Pakistan: formulation of COVID-19 national testing strategy

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Umar Saeed ◽  
Sara Rizwan Uppal ◽  
Zahra Zahid Piracha ◽  
Azhar Rasheed ◽  
Zubair Aftab ◽  
...  
Keyword(s):  
Gold Standard ◽  
Injection Drug Users ◽  
Drug Users ◽  
Diagnostic Testing ◽  
False Negative ◽  
Cross Sectional Study ◽  
Nasopharyngeal Swab ◽  
Rt Pcr ◽  
Cross Sectional ◽  
Negative Results

AbstractRapid diagnosis of SARS-CoV-2 during pandemic enables timely treatment and prevention of COVID-19. Evaluating the accuracy and reliability of rapid diagnostic testing kits is crucial for surveillance and diagnosis of SARS-CoV-2 infections in general population, injection drug users, multi-transfused populations, healthcare workers, prisoners, barbers and other high risk populations. The aim of this study was to evaluate performance and effectiveness of nasopharyngeal swab (NSP) and saliva based rapid antigen detection testing kits in comparison with USFDA approved triple target gold standard real-time polymerase chain reaction. A cross-sectional study was conducted on 33,000 COVID-19 suspected patients. From RT-PCR positive patients, nasopharyngeal swab (NSP) and saliva samples were obtained for evaluation of rapid COVID-19 testing kits (RDT). 100/33,000 (0.3%) of specimens were RT-PCR positive for SARS-CoV-2. Among RT-PCR positive, 62% were males, 34% were females, and 4% were children. The NSP-RDT (Lepu Medical China) analysis revealed 53% reactivity among males, 58% reactivity among females, and 25% reactivity among children. However saliva based RDT (Lepu Medical China) analysis showed 21% reactivity among males and 23% among females, and no reactivity in children. False negative results were significantly more pronounced in saliva based RDT as compared to NSP-RDT. The sensitivity of these NSP-RDT and saliva based RDT were 52% and 21% respectively. The RDTs evaluated in this study showed limited sensitivities in comparison to gold standard RT-PCR, indicating that there is a dire need in Pakistan for development of suitable testing to improve accurate COVID-19 diagnosis in line with national demands.

The influence of prescriber and patient gender on the prescription of benzodiazepines: results from the Florida Medicaid Dataset

CNS Spectrums ◽  
2021 ◽  
pp. 1-5
Author(s):  
Leanna M. W. Lui ◽  
Yena Lee ◽  
Orly Lipsitz ◽  
Nelson B. Rodrigues ◽  
Hartej Gill ◽  
...  
Keyword(s):  
The United States ◽  
Sociodemographic Factors ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Assistance Program ◽  
Patient Gender ◽  
Prescription Rates ◽  
Male Patients ◽  
Using Data ◽  
Main Effects

Abstract Background Benzodiazepine (BZD) prescription rates have increased over the past decade in the United States. Available literature indicates that sociodemographic factors may influence diagnostic patterns and/or prescription behaviour. Herein, the aim of this study is to determine whether the gender of the prescriber and/or patient influences BZD prescription. Methods Cross-sectional study using data from the Florida Medicaid Managed Medical Assistance Program from January 1, 2018 to December 31, 2018. Eligible recipients ages 18 to 64, inclusive, enrolled in the Florida Medicaid plan for at least 1 day, and were dually eligible. Recipients either had a serious mental illness (SMI), or non-SMI and anxiety. Results Total 125 463 cases were identified (i.e., received BZD or non-BZD prescription). Main effect of patient and prescriber gender was significant F(1, 125 459) = 0.105, P = 0 .745, partial η2 < 0.001. Relative risk (RR) of male prescribers prescribing a BZD compared to female prescribers was 1.540, 95% confidence intervals (CI) [1.513, 1.567], whereas the RR of male patients being prescribed a BZD compared to female patients was 1.16, 95% CI [1.14, 1.18]. Main effects of patient and prescriber gender were statistically significant F(1, 125 459) = 188.232, P < 0.001, partial η2 = 0.001 and F(1, 125 459) = 349.704, P < 0.001, partial η2 = 0.013, respectively. Conclusions Male prescribers are more likely to prescribe BZDs, and male patients are more likely to receive BZDs. Further studies are required to characterize factors that influence this gender-by-gender interaction.

scholarly journals Magnitude of Induced Abortion and Associated Factors among Female Students of Hawassa University, Southern Region, Ethiopia, 2019

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Addisu Tadesse Sahile ◽  
Mieraf Shiferaw Beyene
Keyword(s):  
Associated Factors ◽  
Contraceptive Use ◽  
Simple Random Sampling ◽  
Cross Sectional Study ◽  
Induced Abortion ◽  
Southern Region ◽  
Cross Sectional ◽  
Study Setting ◽  
Emergency Contraceptives ◽  
Hawassa University

Objectives. This study was aimed at assessing the magnitude of induced abortion and associated factors among students in Hawassa University, southern region, Ethiopia, 2019. Methods. An institutional-based cross-sectional study was conducted among a total of 422 students selected on the bases of a probability simple random sampling method. A pretested structured questionnaire was used to collect data. Analysis was made with SPSS 20. Descriptive summary and inferential statistics (binary logistic regression) were used with a 95% CI and P value of less than 5% as a level of significance. Findings were presented in tables, figure, and texts. Confidentiality of information was also secured. Results. The prevalence of induced abortion in the study setting was 68.7% (95% CI: 64.15%-73.2%). Participants who used emergency contraceptives had 12 times higher odds of undergoing abortion than those who did not use emergency contraceptives at AOR: 11.95, 95% CI: 5.615-25.326, P<001. Conclusions. A higher prevalence of induced abortion was observed in the study setting. Contraceptive use was the predictor of induced abortion identified. Concerned bodies were recommended to work on the identified determinant of induced abortion in the study setting.

A retrospective analysis of congenital anomalies in congenital hypothyroidism

2020 ◽  
Vol 33 (9) ◽  
pp. 1147-1153
Author(s):  
Fatima Ali Mazahir ◽  
Manal Mustafa Khadora
Keyword(s):  
United Arab Emirates ◽  
Congenital Hypothyroidism ◽  
Clinical Laboratory ◽  
Tertiary Care ◽  
Significant Proportion ◽  
Cross Sectional Study ◽  
High Rate ◽  
Lingual Thyroid ◽  
Cross Sectional

AbstractObjectivesWe evaluated the spectrum of diseases accompanying congenital hypothyroidism (CH) in the United Arab Emirates and compared them with internationally studied patterns.MethodsThe presented retrospective cross-sectional study took place in two government tertiary care centres. In total, 204 patients with a confirmed diagnosis of CH and a minimum period of follow-up of 1 year were included. Patients with Down syndrome, infants born at <35 weeks of gestation, and babies with TORCH (Toxoplasma gondii, Other viruses [HIV, measles, etc.], Rubella, Cytomegalovirus, and Herpes simplex) infections were subsequently excluded from the study.ResultsOf the subjects with CH, 39% had associated extrathyroidal anomalies (ETAs); among these, 25% had a single anomaly. A significant proportion of Arab males were affected by CH as compared to other ethnic groups. Dyshormonogenesis was the commonest aetiological cause (55%) of CH. Males with an ectopic lingual thyroid gland had significant ETAs as compared to females of the same cohort. The most common ETAs were congenital heart disease (16%), followed by urogenital tract anomalies (14%).ConclusionsDetection of a high rate and variability of ETAs associated with CH necessitates the formulation of a structured screening programme including appropriate clinical, laboratory, and imaging tools to detect ETAs at an earlier stage.

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