A retrospective analysis of congenital anomalies in congenital hypothyroidism

2020 ◽  
Vol 33 (9) ◽  
pp. 1147-1153
Author(s):  
Fatima Ali Mazahir ◽  
Manal Mustafa Khadora
Keyword(s):  
United Arab Emirates ◽  
Congenital Hypothyroidism ◽  
Clinical Laboratory ◽  
Tertiary Care ◽  
Significant Proportion ◽  
Cross Sectional Study ◽  
High Rate ◽  
Lingual Thyroid ◽  
Cross Sectional

AbstractObjectivesWe evaluated the spectrum of diseases accompanying congenital hypothyroidism (CH) in the United Arab Emirates and compared them with internationally studied patterns.MethodsThe presented retrospective cross-sectional study took place in two government tertiary care centres. In total, 204 patients with a confirmed diagnosis of CH and a minimum period of follow-up of 1 year were included. Patients with Down syndrome, infants born at <35 weeks of gestation, and babies with TORCH (Toxoplasma gondii, Other viruses [HIV, measles, etc.], Rubella, Cytomegalovirus, and Herpes simplex) infections were subsequently excluded from the study.ResultsOf the subjects with CH, 39% had associated extrathyroidal anomalies (ETAs); among these, 25% had a single anomaly. A significant proportion of Arab males were affected by CH as compared to other ethnic groups. Dyshormonogenesis was the commonest aetiological cause (55%) of CH. Males with an ectopic lingual thyroid gland had significant ETAs as compared to females of the same cohort. The most common ETAs were congenital heart disease (16%), followed by urogenital tract anomalies (14%).ConclusionsDetection of a high rate and variability of ETAs associated with CH necessitates the formulation of a structured screening programme including appropriate clinical, laboratory, and imaging tools to detect ETAs at an earlier stage.

Prevalence and Predictive Factors of Transient and Permanent Congenital Hypothyroidism in Fars Province, Iran

2021 ◽  
Author(s):  
Ashkan Habib ◽  
Alireza Shojazadeh ◽  
Mohadeseh Molayemat ◽  
Asadollah Habib ◽  
Marjan Jeddi ◽  
...  
Keyword(s):  
Incidence Rate ◽  
Congenital Hypothyroidism ◽  
Predictive Factors ◽  
Cross Sectional Study ◽  
Thyroid Stimulating Hormone ◽  
Fars Province ◽  
Venous Sampling ◽  
Cross Sectional ◽  
Outpatient Visits

Abstract Introduction: There is no data on the number as well as the prevalence of congenital hypothyroidism (CH) in the Fars province. Hence, we designed this study to analyze the latest data and the possible predictive factors on transient and permanent CH in this province.Method: This cross sectional study is based on the Fars province screening data from 2013 till 2016. A total of 294,214 newborns were screened with 938 confirmed cases of CH, which were included in this study. After recall and completion of the missing data, follow-up data for 642 CH cases with thyroid stimulating hormone (TSH) concentrations and levothyroxine doses for ten outpatient visits and final transient vs. permanent CH diagnosis were included.Results: The incidence rate was 1:313.66, and out of the 642 CH cases, 66.04% had permanent CH, while 33.96% had transient CH. TSH level trend during the outpatient visits were not statistically different between the two groups (P=0.312). A cutoff point of >2.25 levothyroxine µg/kg (sensitivity: 76.11%, specificity: 58.52%) at the third year and a TSH concentration of >43.35 mIU/L at the venous sampling (initial TSH) (sensitivity: 31.66%, specificity: 90.32%) were the predictive factors for permanent CH.Conclusion: Fars province has one of the highest incidence rate of CH in Iran. Levothyroxine dose at the 3rd year and the 1st venous TSH sample are the predictive factors for permanent CH in the Iranian population; however, TSH concentrations during follow ups are unreliable predictors.

scholarly journals Health Status of School Going Children: A Cross sectional study in urban area of Jhalawar District, Rajasthan

Healthline ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 15-21
Author(s):  
Manish Jain ◽  
Mayank Jain ◽  
Vinod Kumar ◽  
Kapil Garg ◽  
Asif A Qureshi ◽  
...  
Keyword(s):  
Health Status ◽  
Dental Caries ◽  
Urban Area ◽  
Tertiary Care ◽  
Significant Proportion ◽  
Cross Sectional Study ◽  
Refractive Errors ◽  
Sectional Study ◽  
Government Schools ◽  
Cross Sectional

Introduction: The school going age is a formative period, both physically as well as mentally. Poor health status in school aged children is among the causes of poor class performance and high absenteeism. Objectives: to assess the health and nutritional status of the school going children in urban area and to determine the association of health problems with age and gender. Method: A cross sectional study was carried out in government schools of urban field practice area of tertiary care institute, Jhalawar, Rajasthan. Study was carried out among 2193 students in four government schools. A pretested, semi structured questionnaire was used for collection of data on socio-demographic characters and their health profile. A detailed clinical examination was done from head to toe for every child. Weight and height were measured. Data was entered into the Microsoft Excel 10. Chi square test of significance was used for statistical analysis. Results: Most common health problem was dental caries (15.0%) followed by refractive errors (13.1%) and pallor (12.6%). Proportions of pallor and refractive error were significantly increased with increase in age of study participants. 16.8% of the students were found to be having thinness. Moderate stunting was present in 7.3% students. Conclusion: Dental caries, refractive errors and pallor were the common morbidities. A significant proportion of school children were undernourished.

CROSS SECTIONAL STUDY OF CAUSES AND DETERMINANTS OF STILLBIRTHS AT TERTIARY CARE TEACHING HOSPITAL

2021 ◽  
pp. 41-43
Author(s):  
Chavan L. G ◽  
Bangal V. B. ◽  
Poorna M. N.
Keyword(s):  
Very Low Birth Weight ◽  
Tertiary Care ◽  
Birth Asphyxia ◽  
Cross Sectional Study ◽  
High Rate ◽  
Child Health Services ◽  
Sectional Study ◽  
Cross Sectional ◽  
Risk Pregnancy ◽  
Common Causes

Introduction- Stillbirth rates are unacceptably high in developing countries. It reects the suboptimum quality of maternal and child health services. Material And Methods- Prospective observational cross sectional study, carried out for one year duration at tertiary care referral hospital in central India. Results-There were 9165 deliveries and 9318 babies born in the hospital.There were 318 stillbirths of which 245(77%) were antepartum stillbirths and 73(23%) were intra-partum stillbirths. The stillbirth rate in the present study was 34/1000 births. Ante-partum haemorrhage (36%) and pregnancy induced hypertension (21%) were most common causes of ante-partum stillbirths where as extreme prematurity with very low birth weight (41%), birth asphyxia, meconium aspiration (21%) and intra-partum haemorrhage (15%) were common causes of intra-partum stillbirths. Conclusion- There is high rate of stillbirths in the present study. Health education, improvement of maternal nutrition, regular antenatal check-ups, high risk pregnancy identication and timely referral and institutional deliveries will help in preventing large number of stillbirths.

scholarly journals The profile of patients’ complaints in a tertiary care hospital in South India

2018 ◽  
Vol 5 (8) ◽  
pp. 3567
Author(s):  
Mohammed Jezeel Nalakath ◽  
P. M. Thasneem ◽  
K. V. Deepak ◽  
N. A. Uvais
Keyword(s):  
Medical Staff ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
High Standard ◽  
Cross Sectional Study ◽  
High Rate ◽  
Care Hospital ◽  
Cross Sectional ◽  
Study Results ◽  
Research Population

Background: Complaints from patients and their carers are important indicators of problems in a healthcare system and provide valuable insights into safety-related problems within healthcare organisations. The objectives of the present study are to identify the frequency distribution of the people complained about, the units complained about and the total number of complaints.Methods: We employed a descriptive, cross-sectional study to conduct this research. The research population included cases registered at the complaints unit of a tertiary care hospitals in selected months of May 2017 to August 2017. The data were collected through observation of available documents. Excel software program was used for data analysis.Results: The administration received 692 complaints between the study period. The highest rate of complaints was filed against admission process (30.06%) and the lowest rate of complaints are filed against staff (2.51%). Our study results showed a significantly less complaints against nursing staff and no complaints against medical staff, indicates that the nursing and medical staff of the hospital might be observing medical ethics and professional commitment to a high standard and communicating well with the patients. High rate of complaints against admission unit, house keeping unit and high billing amount indicates the unrealistic expectations prevailing in the minds of clients from the health care provider.Conclusions: The current study generated the profile of patient’s complaints in a tertiary care hospital running in a charitable model. Such data can be utilised to identify common problems and to plan strategies. 

scholarly journals Maternity handover in Kerala: a cross sectional study

2018 ◽  
Vol 5 (9) ◽  
pp. 3760 ◽  
Author(s):  
Aadil Sheikh ◽  
Jessica Dunphy ◽  
Claire Humphries ◽  
Christina MacArthur ◽  
Semira Manaseki-Holland
Keyword(s):  
Healthcare Provider ◽  
Tertiary Care ◽  
Obstetric Care ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Community Health Services ◽  
High Rate ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Impact

Background: The objective of the study was to explore the referral system from the community to hospital obstetric care in Kerala, India.Methods: Cross-sectional study. A total of 206 obstetric inpatients in 3 hospitals in Kerala, India completed an orally-administered questionnaire regarding referral and attitudes towards healthcare information.Results: Among 206 respondents, 19 (9%) had been referred from another healthcare provider.  In multivariate analysis, referral was independently associated with being in a tertiary hospital (p<0.001). At total of 17 referred women received a document containing hand-written notes from their previous healthcare provider. Just 3 of the documents available to view were formal referral documents; others were test results and/or hospital notes. A total of 170 (86%) of the 206 women thought that receiving documents such as referral letters was important; mostly because it helped them understand their condition and explain it to others (91%).Conclusions: A high rate of self-referral (91%) was reported by obstetric inpatients. It appears that some women who are referred do not receive a formal referral document. Participants thought that receiving referral documents was important. A strong health system requires transfer of information between primary and secondary/tertiary care services, which India is seeking to develop. Further research is needed into why women are not accessing community health services and the impact of the content of referral documents on patient care. 

scholarly journals A Clinico-Etiological Study of Erythroderma in Adults in a Tertiary Care Centre

2021 ◽  
Vol 10 (37) ◽  
pp. 3213-3219
Author(s):  
Jagaragallu Amrutha ◽  
Narasimha Rao Netha Gurram ◽  
Padmaja Pinjala ◽  
Bhumesh Kumar Katakam ◽  
Rajeev Singh Thakur
Keyword(s):  
Clinical Laboratory ◽  
Age Of Onset ◽  
Common Factor ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Tertiary Care Centre ◽  
Cross Sectional ◽  
Female Ratio ◽  
Mortality And Morbidity ◽  
Etiological Study

BACKGROUND Erythroderma is a clinical entity that may cause severe systemic manifestations. The difficulty with erythroderma lies in finding the underlying aetiology. It is imperative to demonstrate precise aetiology whenever possible so that distinct therapy may be initiated. At times, despite finding the aetiology, relapses constitute a great menace. The purpose of our study was to assess the clinical profile and aetiology of erythroderma. Besides, the study also illustrated factors leading to relapses; such studies are rare in literature. METHODS This hospital-based, cross-sectional study included 88 patients of erythroderma of either sex and age more than 18 years; their clinical, laboratory, histopathological findings, treatment and outcome were studied. RESULTS The mean age of onset was 47.3 ± 12.35 years with the male to female ratio being 2.38:1. The most common cause of erythroderma was pre-existing dermatoses (67 %) followed by drugs (10.2 %), infections (3.4 %), malignancies (4.54 %), and idiopathic (14.7 %). Psoriasis was the predominant aetiology (45.4 %) among the pre-existing dermatoses with a maximum number of relapses (P = 0.02). Psoriasis was significantly associated with pruritus (P = 0.001), subungual hyperkeratosis (P = 0.0001), palmoplantar keratoderma (P = 0.001). Clinicohistological association was found in 64.6 % of cases. Mortality was seen in 6.8 % of cases. CONCLUSIONS As in previous studies, pre-existing dermatoses were the most common causes in our study; albeit, a special emphasis on factors leading to relapses was given to prevent further episodes. The most common factor of relapse was uncontrolled comorbid disorders (diabetes and hypertension) followed by medication nonadherence. Hence, our study suggests a need for more effective comorbidity management and creating awareness regarding judicial use of drugs which can go far in preventing mortality and morbidity. KEY WORDS Erythroderma, Adults, Aetiology, Relapses, Comorbidities.

scholarly journals KNOWLEDGE AND PERCEPTIONS OF VITAMIN D DEFICIENCY AMONG THE UNITED ARAB EMIRATES POPULATION

2019 ◽  
pp. 183-186 ◽  
Author(s):  
OSAMA MOHAMED IBRAHIM ◽  
NOOR KIFAH AL-TAMEEMI ◽  
DALIA DAWOUD
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Blood Level ◽  
United Arab Emirates ◽  
Cross Sectional Study ◽  
Vitamin D Insufficiency ◽  
Abu Dhabi ◽  
Sectional Study ◽  
Cross Sectional

Objectives: The purpose of this study is to assess the Vitamin D deficiency awareness and perceptions between the United Arab Emirates (UAE) population. Methods: A cross-sectional study was done among the population of two emirates at the UAE: Abu Dhabi and Sharjah. Results: Overall, 434 participants completed the survey. Majority of people were aware of phenomenon of Vitamin D deficiency, but only 21.4% of them knew that sunlight is considered the main source of Vitamin D. Moreover, less than half of participants check their Vitamin D blood level regularly and around 55% of them follow-up with their physicians after completing the treatment. High proportion of participant females spend <1 h outdoors (60%) and use sunscreen daily (55%) that cause higher prevalence of Vitamin D deficiency among females than males (83% vs. 42%). Conclusion: This research gives some insights regarding the UAE population’s awareness and perceptions of Vitamin D insufficiency. Decreased awareness of sunlight exposure as a major source of Vitamin D, in addition to lifestyle, contributed to Vitamin D deficiency problem among the UAE population, in general, and in females, in particular.

scholarly journals Chronic headache among general practice out patients in a tertiary care hospital, Eastern Nepal

2017 ◽  
Vol 13 (2) ◽  
pp. 22-29
Author(s):  
Rabin Bhandari ◽  
R Bhandari ◽  
DR Shakya ◽  
R Maskey ◽  
M Paudel ◽  
...  
Keyword(s):  
General Practice ◽  
Chronic Headache ◽  
Tertiary Care ◽  
Significant Proportion ◽  
Cross Sectional Study ◽  
Tension Type Headache ◽  
Ethical Review ◽  
Care Hospital ◽  
Research Committee ◽  
Cross Sectional

Background: The term chronic headache is commonly taken as headache lasting for more than three months. It is common in general practice with minimal research on the topic in Nepal. Objective: To sort out the common diagnoses of chronic headache and to study the clinical features and demographic profile of patients presenting with chronic headache.Method: A descriptive cross sectional study was conducted (2012 August to 2013 August) at General Practice outpatients in BP Koirala Institute of Health Sciences, a medical university in eastern Nepal. Approval and ethical clearance was taken from Research Committee and Institutional Ethical Review Board. Descriptive statistical analysis was done.Result: 168 patients constituting 1% of outpatient visits presented due to chronic headache. Mean age was 29.57 years (SD 10.53) and female to male ratio was 3.67. Mean number of days of headache was 19.46 days (SD 4.62). Numerical pain score was reported at 7.1/10 (SD 1.85). The mean duration of presentation was 22 months (SD 11). 40% reported impaired activity of more than one week. Headache was classified as chronic migraine in 20.2%, chronic tension type headache in 16.7%, and chronic daily persistent headache in 11.9%. The diagnosis did not fit into any diagnostic criteria in 51.2% cases. Conclusion: Chronic headache is common in females and young age group. Patients present late despite significant pain scores. Significant proportion is still unclassified.Health Renaissance 2015;13(2): 22-29

scholarly journals Parental experiences and preferences as participants in pediatric research conducted in the emergency department

CJEM ◽  
2017 ◽  
Vol 20 (3) ◽  
pp. 409-419 ◽  
Author(s):  
Antonia S. Stang ◽  
Stephen B. Freedman ◽  
Angelo Mikrogianakis ◽  
Graham C. Thompson ◽  
Janie Williamson ◽  
...  
Keyword(s):  
Emergency Department ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Pediatric Research ◽  
Waiting Room ◽  
Cross Sectional ◽  
Web Based ◽  
Parental Experiences ◽  
Separate Area

ABSTRACTObjectiveTo determine parental experiences and preferences regarding the conduct of pediatric research in an emergency department (ED) setting.MethodsWe conducted a cross-sectional study of parents of children ages 0 – 14 years who visited the ED of a tertiary care children’s hospital. Parents completed a Web-based survey designed to assess perceptions regarding: 1) background/training of research personnel, 2) location and timing of research discussions, and 3) factors influencing their consent/refusal decision.ResultsParents totalling 339 were approached, and 227 (67%) surveys were completed. Overall, 87% (197/227; 95% confidence interval [CI] 83, 92) reported they would be comfortable being approached by a university student to discuss research. This proportion did not change when stratified by the child’s gender, illness severity, or season of visit. Whereas only 37% (84/227; 95% CI 31, 43) of respondents would be comfortable being approached in the waiting room, 68% (154/227; 95% CI 62, 75) would be comfortable if approached in a separate area of the main waiting room. The majority reported comfort with follow-up via email (83%; 188/227; 95% CI 78, 88) or telephone (80%; 182/227; 95% CI 75, 85); only 51% (116/227; 95% CI 44, 57) would be comfortable with a scheduled follow-up visit in the hospital. Participants identified potential complications or side effects as the most common reason for declining consent (69%; 157/227; 95% CI 63, 75).ConclusionsThe majority of parents are comfortable being approached by trained university students, preferably in a separate area of an ED waiting room, and email and telephone follow-ups are preferred over a scheduled re-visit.

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