scholarly journals Association of Non HDL-Cholesterol and other lipid parameters in patients with Acute Coronary Syndrome.

2021 ◽  
Vol 29 (01) ◽  
pp. 82-87
Author(s):  
Syeda Sabahat Haider ◽  
Muhammad Shahid ◽  
Khalid Razaq ◽  
Shama Iqbal ◽  
Muhammad Tariq Ghafoor ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Total Cholesterol ◽  
Statistical Significance ◽  
Sampling Technique ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Control Group ◽  
P Value ◽  
Cross Sectional ◽  
Coronary Syndrome

Objective: To determine the frequency of hypercholesterolemia in patients who are diagnosed with acute coronary syndrome and to also document the association of Non HDL-C with Acute coronary syndrome in these patients. Study Design: Observational Cross Sectional study. Setting: Department of Cardiology and Pathology of Sheikh Zayed Hospital, Rahim Yar Khan. Period: September 2019 to February 2020. Material & Methods: One hundred and thirty five patients with Acute coronary syndrome were included using non probability purposive sampling technique and equal number of patient who visited the outpatient department or admitted in indoor with complaints other than ACS were taken as control (n=135). Frequency and percentages were calculated and odd ratio was determined to see the association. Statistical significance was set at P-value<0.05. Results: Patient’s mean age was 55.5±12.4 years and there were 98(73%) male and 37(27%) female. Higher Non HDL-C (>130mg/dl) was found in 120(88.9%) cases and in 38(28.1%) controls with odd ratio 20.4211 at 95 %CI and p value <0.001.Hypercholesterolemiawas seen in 49(36.3%) of the cases while in 21(15.6%) of control group (without ACS) with odd ratio of 3.3 and p-value <0.001. Odds ratio was maximum for Non HDL cholesterol, followed by LDL cholesterol, HDL cholesterol and Total cholesterol. Conclusion: Non-HDL cholesterol showed a good association in patients with ACS than with primary target LDL-C or total cholesterol.

scholarly journals Gambaran Profil Lipid pada Pasien Sindrom Koroner Akut di Rumah Sakit Khusus Jantung Sumatera Barat Tahun 2011-2012

2014 ◽  
Vol 3 (2) ◽  
Author(s):  
Fitri Zahara ◽  
Masrul Syafri ◽  
Eti Yerizel
Keyword(s):  
Acute Coronary Syndrome ◽  
Lipid Profile ◽  
Total Cholesterol ◽  
Ldl Cholesterol ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Coronary Syndrome ◽  
High Level ◽  
Heart Hospital

AbstrakPenyakit kardiovaskuler merupakan penyebab kematian nomor satu secara global. Salah satu penyakit kardiovaskuler itu adalah Sindrom Koroner Akut (SKA) yang merupakan keadaan gawat darurat dari Penyakit Jantung Koroner (PJK). Salah satu faktor risiko SKA adalah perubahan dari kadar fraksi lipid yaitu kolesterol total, kolesterol LDL, kolesterol HDL, dan trigliserida yang dikaitkan dengan pembentukan plak aterosklerosis. Penelitian ini bertujuan untuk mengetahui gambaran profil lipid pada pasien SKA di rumah sakit khusus jantung Sumatera Barat tahun 2011-2012. Telah dilakukan penelitian deskriptif dengan bentuk cross sectional study dan pendekatan retrospective menggunakan data rekam medik mengenai hasil pemeriksaan profil lipid (kolesterol total, HDL, LDL, dan trigliserida) di rumah sakit khusus jantung Sumatera Barat untuk mengetahui gambaran profil lipid pada pasien SKA tahun 2011-2012. Hasil penelitian ini menemukan 98 kasus SKA. hasil ini menunjukkan bahwa pasien SKA dengan kadar kolesterol total tinggi adalah 44 orang (44,9%) dan normal sebanyak 54 orang (55,1%), pasien SKA dengan kadar kolesterol HDL rendah adalah 63 orang (64,3%) dan normal sebanyak 35 orang (35,6%), pasien SKA dengan kadar kolesterol LDL tinggi adalah 44 orang (44,9%) dan normal sebanyak 54 orang (55,1%), dan pasien SKA dengan kadar trigliserida tinggi adalah 21 orang (21,4%) dan normal sebanyak 77 orang (78,6%). Kejadian SKA terbanyak adalah STEMI sebanyak 51 kasus (52%), kemudian NSTEMI sebanyak 24 kasus (24,5%) dan yang paling sedikit adalah angina pektoris tak stabil sebanyak 23 kasus (23,5%) frekuensi umur terbanyak dari pasien SKA adalah 40-59 tahun, jenis kelamin terbanyak dari pasien SKA adalah laki-laki sekitar 74,5%. Penelitian menunjukkan jumlah bahwa pasien SKA yang memiliki kadar kolesterol total yang tinggi lebih sedikit daripada yang normal, kadar kolesterol HDL yang rendah lebih banyak daripada yang normal, kadar kolesterol LDL yang tinggi lebih sedikit daripada yang normal, kadar trigliserida yang tinggi lebih sedikit daripada yang normal, kasus SKA terbanyaKata kunci: Sindrom Koroner Akut, kolesterol total, kolesterol LDL, kolesterol HDL, trigliseridaAbstractCardiovascular diseases are the number one cause of death globally. One of the cardiovascular disease is Acute Coronary Syndrome (ACS) which is a state of emergency from Coronary Heart Disease (CHD). One of the risk factors for ACS is a change in the levels of lipid fractions such as total cholesterol, LDL Cholesterol, HDL Cholesterol and triglycerides which are associated with the formation of atherosclerotic plaque. This study aims to determine description of lipid profile in patients with acute coronary syndrome at the heart hospital of west sumatera 2011-2012. Descriptive research has been conducted with a a cross-sectional study and a retrospective approach using medical record about the result of lipid profile test (total cholesterol, HDL, LDL, and triglycerides) at the heart hospital of West Sumatera to describe the lipid profile in patients with ACS in 2011-2012. The results of this study found 98 cases of ACS. It showed that ACS patients with high total cholesterol levels are 44 people (44,9%) and normal are 54 people (55,1%), acute coronary syndrome patients with low levels of HDL cholesterol are 63 people (64,3%) and normal are 35 people (35,6%), acute coronary syndrome patients with high levels of LDL cholesterol are 44 people (44,9%) and normal are 54 people (55,1%), acute coronary syndrome patients with high levels of triglyceride are 21 people (21,4%) and normal are 77 people (78,6%), the highest incidence of SKA is STEMI with 51 cases (52%), then NSTEMI with 24 cases (24,5%) and the lowest incidence is unstable angina pectoris with 23 cases (23,5%), most age of the patients of ACS are 40-59 years old, the most gender of ACS are male about 74,5%. Research shows that the number of ACS patients who have a high level of total cholesterol are less than normal, low levels of HDL cholesterol are more than normal, high level of LDL cholesterol are less than normal, high level of triglyceride are less than normal, most incidens of ACS is STEMI then NSTEMI and the lowest is unstable angina pectoris, most age of ACS patients are 40-59 years, and most of gender are men.Keywords:acute myocardial infarction, total cholesterol, LDL cholesterol, HDL cholesterol, triglyceride

scholarly journals Early implanon discontinuation and associated factors among women ever used implanon in Mettu district, Oromia regional state, southwest Ethiopia, 2021

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Hana Tesfaye ◽  
Ebissa Negara ◽  
Kenbon Bayisa
Keyword(s):  
Side Effects ◽  
Associated Factors ◽  
Statistical Significance ◽  
Descriptive Analysis ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Relative Effect ◽  
Outcome Variable ◽  
P Value ◽  
Cross Sectional

Abstract Background Implanon is an effective form of long-acting reversible contraceptive used to prevent conception with a clinical failure rate of less than one per 100 users. However, in sub-Saharan countries the utilization of implanon was very low. Regardless of low utilization; its early discontinuation is very common in most developing countries including Ethiopia. Objectives To assess the prevalence of early implanon discontinuation and associated factors among women ever used implanon in Mettu district. Methods A community based cross-sectional study design was conducted from October 11 to December 4, 2020 G C. A total of 430 women were included in the study by systematic random sampling technique. Data were entered into epi data version 3.1 and analyzed by SPSS version 25.0. Descriptive analysis was computed to describe descriptive results. Logistics regression was computed to see the relative effect of factors on the outcome variable. Adjusted odds ratio was calculated with 95% confidence intervals to show strength of association and p-value < 0.05 was used to declare statistical significance. The finding of the study was presented using narrations, tables and chart. Result The total proportion of early implanon discontinuation among 430 mothers was 19.3%. Women who did not counseled about the presence of alternatives methods [AOR = 2.28: 95% CI (1.22–4.26)], women who experienced dizziness after insertion of implanon [AOR = 1.90: 95% CI (1.06–3.43)] and being having menstrual disturbance after insertion of implanon [AOR = 2.17: 95% CI (1.16–4.08)] were significantly associated with early implanon discontinuation. Women who were counseled about the advantage of implanon [AOR: 0.49: 95% CI (0.28–0.87)] were protective from early implanon discontinuation. Conclusion and recommendation Early implanon discontinuation among mothers was found to be high. Hence, effective counseling on advantages and side effects of implanon and proper management of the side effects should be made to increase implanon retention.

scholarly journals Anthropometric Parameters and Total Cholesterol to HDL Cholesterol Ratio in Long-Distance Cyclists (Indonesia North Coast and Tour de Borobudur 2017 Study)

2018 ◽  
Author(s):  
Mahalul Azam ◽  
Sri Ratna Rahayu ◽  
Arulita Ika Fibriana ◽  
Hardhono Susanto ◽  
Martha Irene Kartasurya ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Binary Logistic Regression ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
North Coast ◽  
P Value ◽  
Anthropometric Parameters ◽  
Long Distance ◽  
Cross Sectional ◽  
Cholesterol Ratio

Total-Cholesterol(TC) to HDL-Cholesterol(HDL-C) ratio in athletes is well-known better than sedentary people. However, there is lack of information about comparison of TC/HDL-C in different groups of cyclists based on cycling touring characteristics and anthropometry parameters. This study was to compare TC/HDL-C ratio among groups based on type of tour participated in cyclists population.Eighty-eight participants were recruited in this cross-sectional study. Mean differences of parameters between groups analyzed by One-Way Anova test and independent t-test, while multivariate analyses was done by binary logistic-regression. P value &lt;0.05 was considered to statistical significance.TC/HDL-C ratio in all groups were less than 4.5. There is no differences of TC-levels (NC240K: 216.6±55.04, TdB140K: 208.1±27.13, TdB100K: 203.1±31.95; p=0.427). But there is significantly different of HDL-C (NC240K: 68.9±19.09, TdB140K: 52.1±13.9, TdB100K: 53.6±12.45; p=0.0001) and TC/HDL-C ratio (NC240K: 3.3±1.12, TdB140K: 4.2±1.07, TdB100K: 4.0±1.06; p=0.007). Based on TC/HDL ratio (≥4 or &lt;4) groups, there were differences of weight, BMI, waist-circumference, hip-circumference and type of cycling-touring (p&lt;0.05). Finally BMI and type of cycling-touring were the most-influenced factor.Long-distance cyclists have a synergistic effect of lipid profile and anthropometry measurements, and the heavier cycling touring participated that represent cycling training habits tend to have lower TC/HDL ratio(&lt; 4).

scholarly journals Fragmented QRS Complex as a Predictor of Multivessel Disease in Acute Coronary Syndrome

2017 ◽  
pp. 130-6
Author(s):  
Idar Mappangara ◽  
Abdul Hakim Alkatiri ◽  
Stefan Hendyanto
Keyword(s):  
Acute Coronary Syndrome ◽  
Logistic Regression ◽  
Cross Sectional Study ◽  
Multivessel Disease ◽  
P Value ◽  
Qrs Complex ◽  
Cross Sectional ◽  
Coronary Syndrome ◽  
Fragmented Qrs ◽  
History Of

Background: The incidence of multivessel disease in acute coronary syndrome (ACS) is expected to be identified as early as possible in order to perform optimal management. The presence of multivessel disease can lead to ischemia or myocardial infarction. Fragmented QRS complex (fQRS) is a new electrocardiography (ECG) parameter that has been proven to be caused by ischemia or myocardial infarction.Methods: A cross-sectional study. Patients with ACS that admitted at Dr. Wahidin Sudirohusodo Makassar since December 2014 - March 2015 who are eligible were enrolled in this study.Presence of fQRS evaluated on first 12-lead ECG at hospital admission. Presence of multivessel disease based on coronary angiography. Data were analyzed by logistic regression. Data was significant if the p-value<0.05.Results: There are 63 subjects (56 men and 7 women) included in this study. Older age, history of ACS before, presence of dyslipidemia, and presence of fQRS were significantly more often in group with multivessel disease. After analyzed with logistic regression, the fQRS was the only significant predictor of multivessel disease with p value 0.003 and odds ratio 13.28.Conclusion: Presence of fQRS in the first 12-lead ECG when admitted to the hospital was an independent predictor of multivessel disease in patients with ACS.

scholarly journals ACUTE CORONARY SYNDROME;

2017 ◽  
Vol 24 (03) ◽  
pp. 409-413
Author(s):  
Naveed Aslam Lashari ◽  
Nadia Irum Lakho ◽  
Sarfaraz Ahmed Memon ◽  
Ayaz Ahmed ◽  
Muhammad Fahad Waseem
Keyword(s):  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Coronary Syndrome ◽  
Study Results ◽  
Artery Obstruction ◽  
Conventional Risk Factors ◽  
Typical Chest Pain

Introduction: ACS is defined as the cluster of symptoms arising due to the rapiddrop of blood flow to the heart because of coronary artery obstruction. It is stated that worldwidearound 17 million people die due to cardiovascular diseases of which half of the deaths arereported due to ACS. Chest pain is known to be the most leading factor associated with ACS.Objectives: To determine the frequency of acute coronary syndrome, its types and commoncontributing factors in patients presenting with typical chest pain in a secondary care hospital.Study Design: Cross sectional study. Setting: Medical Unit, PAF Hospital Mushaf Sargodha.Period: October 2013 to March 2014. Methodology: A total of 280 patients of either gender,aged 20 to 80 years presented with typical chest pain with or without conventional risk factorswere included in the study. Results: Majority (68.9%) was males and 31.1% were female. Acutecoronary syndrome was observed in 131(46.8%) patients. Out of these 131 patients, 55% hadNSTEMI, 28.2% had unstable angina and 16.8% had STEMI. A higher proportion of femaleswere found to have ACS as compared to males (75.9% vs 33.7%, P-value<0.0001). Out of131 patients, 40.5% were diabetic, 29.8% were hypertensive 16% were hyperlipidemic, while13.7% were smokers. Conventional risk factors except smoking were observed more in femalesas compared to males. Conclusion: Majority of patients with acute coronary syndrome werefemales and diabetic. NSTEMI was the most common type of ACS. Prevalence of conventionalrisk factors was found more in females with ACS.

scholarly journals Prevalence of depression and its association with parental neglect among adolescents at governmental high schools of Aksum town, Tigray, Ethiopia, 2019: A cross sectional study

2019 ◽  
Author(s):  
Enguday Tirfeneh ◽  
Mengesha Srah
Keyword(s):  
High Schools ◽  
Statistical Significance ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Mental Illnesses ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Parental Neglect ◽  
Prevalence Of Depression

Abstract Background depression is one of the most serious and prevalent mental illnesses that can result in serious disability and ending life by committing suicide and homicide. The risks of having depression are substantially higher in persons who have parental neglect when compared to the general population.Objective To detect prevalence of depression and its association with parental neglect among adolescents in governmental high schools at Aksum town, Tigray, Ethiopia 2019Method A facility based cross-sectional study was conducted from January 1-30/2019 at Aksum town high schools. Public health questionnaire was used in this study to detect Depression. Study participants were selected using simple random sampling technique. Data was collected with face to face interview. Data was analyzed using statistical package for social science version 22. Bivariate and multivariate logistic regressions were used to see the association between depression and parental neglect. Adjusted Odds ratio at a p-value <0.05 with 95% confidence interval was taken to declare statistical significance of variables.

scholarly journals Knowledge of prevention of COVID-19 among the general people in Bangladesh: A cross-sectional study in Rajshahi district

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243410
Author(s):  
Md. Masud Rana ◽  
Md. Reazul Karim ◽  
Md. Abdul Wadood ◽  
Md. Mahbubul Kabir ◽  
Md. Mahidul Alam ◽  
...  
Keyword(s):  
Family Income ◽  
Preventive Measures ◽  
Nuclear Family ◽  
Statistical Significance ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Government

Background Until now, no vaccine or effective drug is available for the control, prevention, and treatment of COVID-19. Preventive measures are the only ways to be protected from the disease and knowledge of the people about the preventive measures is a vital matter. Objectives The aim of the study was to assess the knowledge of the general people in Rajshahi district, Bangladesh regarding the COVID-19 preventive measures. Methodology This cross sectional study was conducted from March 10 to April 25, 2020. Data were collected with a semi-structured questionnaire from 436 adult respondents selected by using a mixed sampling technique. Frequency analysis, chi-square test, and logistic regression model were utilized in this study. SPSS (IBM, Version 22) was used for data analysis. 95% confidence interval and p-value = 0.05 were accepted for statistical significance. Results Only 21.6% of the respondents had good knowledge of the COVID-19 preventive measures. The highest 67.2% of them knew that washing hands with soap could prevent the disease, but contrarily, the highest 72.5% did not know that avoidance of touching mouth, nose, and eyes without washing hands was a preventive measure. Only 28.4% and 36.9% of the respondents knew that maintaining physical distancing and avoiding mass gatherings were measures of prevention of COVID-19 respectively. The younger age (≤25 years), low family income (≤15,000 Bangladeshi Taka (BDT), occupation others than business and service, and nuclear family had the lower odds of having no/less knowledge about the preventive measures. Conclusions The knowledge level of the general people regarding prevention of COVID-19 was alarmingly low in Bangladesh. The government of Bangladesh, health policy makers and donor agencies should consider the findings and take immediate steps for improving knowledge of the public about prevention of the disease.

scholarly journals Anthropometric-Parameters and Total-Cholesterol to HDL-Cholesterol Ratio are Better in Long-Distance Cyclists (Indonesia North Coast and Tour de Borobudur 2017 Study)

2018 ◽  
Vol 14 (2) ◽  
pp. 186-194
Author(s):  
Mahalul Azam ◽  
Sri Ratna Rahayu ◽  
Arulita Ika Fibriana ◽  
Hardhono Susanto ◽  
Martha Irene Kartasurya ◽  
...  
Keyword(s):  
Total Cholesterol ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Influential Factor ◽  
North Coast ◽  
P Value ◽  
Anthropometric Parameters ◽  
Long Distance ◽  
Cross Sectional ◽  
Cholesterol Ratio

Total-Cholesterol (TC) to HDL-Cholesterol (HDL-C) ratio in athletes is well-known to be better than sedentary people. However, information about comparison of TC/HDL-C in different groups of cyclists based on cycling touring characteristics and anthropometry parameters is lacking. This study aimed to compare TC/HDL-C ratio between groups based on the type of tour in cyclists population. Eighty-eight participants were recruited in this cross-sectional study. Mean differences of parameters between groups was analyzed by One-Way Anova and independent t-test, whereas multivariate analyses was conducted by binary logistic-regression. P value <0.05 was considered statistically significant. TC/HDL-C ratio in all groups were less than 4.5. There is no differences of TC-levels (NC240K: 216.6±55.04, TdB140K: 208.1±27.13, TdB100K: 203.1±31.95; p=0.427). But there is significantly different level of HDL-C (NC240K: 68.9±19.09, TdB140K: 52.1±13.9, TdB100K: 53.6±12.45; p=0.0001) and TC/HDL-C ratio (NC240K: 3.3±1.12, TdB140K: 4.2±1.07, TdB100K: 4.0±1.06; p=0.007). Between TC/HDL ratio groups (≥4 or <4), there were differences of weight, BMI, waist-circumference, hip-circumference and type of tour (p<0.05). Finally, BMI and type of tour were the most influential factor. Long-distance cyclists have a synergistic effect of lipid profile and anthropometry measurements, and heavier cycling tour participant, that represent cycling training habits, tend to have lower TC/HDL ratio(< 4).

scholarly journals Acute Coronary Syndrome and patient behavior factors in overcoming the event of chest pain in pre hospital phase

2020 ◽  
Author(s):  
Cipto Susilo ◽  
Mochammad Bagus Qomaruddin ◽  
Mellani Puji Fahrera
Keyword(s):  
Acute Coronary Syndrome ◽  
Chest Pain ◽  
Complex Disease ◽  
Sampling Technique ◽  
P Value ◽  
Behavioral Factors ◽  
Cross Sectional ◽  
Over The Counter ◽  
Coronary Syndrome ◽  
Design And Methods

Background: Acute coronary syndrome (ACS) is a complex disease induced by thrombosis, which causes unstable angina (UA), acute myocardial infarction (AMI) or sudden cardiac death. It is important to rapidly detect the presence of chest pain to conduct the pre-hospital phase. This study aims to analyze the behavioral factors of patients suffering from ACS in overcoming the incidence of chest pain in the prehospital phase. Design and Methods: The consecutive sampling technique and cross-sectional method were used to obtain data from a sample of 110 outpatient respondents at the Community- Integrated Health Center.Results: After the logistic regression test, a significant relationship was found between the occurrence of chest pain (Pvalue = 0.040), with compressive behavior factors, buying over the counter drugs (P-value = 0.001), massaging and rubbing with oil (P-value = 0.046). Conclusions: In conclusion, the significant behavioral factors associated with ACS sufferers in dealing with the occurrence of chest pain in the pre-hospital phase are due to the act of buying OTC drugs and the habit of massaging or rubbing with oil.

scholarly journals Underweight and Factors Associated Among Lactating Mothers In Dodata District, Arsi Zone, Oromia Regional State, Ethiopia,2021

2021 ◽  
Author(s):  
Hawa Kedir ◽  
Godana Arero
Keyword(s):  
Rural Areas ◽  
Statistical Significance ◽  
Sampling Technique ◽  
Simple Random Sampling ◽  
Cross Sectional Study ◽  
P Value ◽  
Cross Sectional ◽  
Lactating Mothers ◽  
Arsi Zone ◽  
Low Bmi

Abstract Background: An underweight individual is a somebody whose body weight is considered too low (BMI <18.5) to be healthy. The similar idea applies to lactating mothers. However, little is known about underweight status among lactating women in the study area. The objective of study to assess incidence of underweight and related issues among lactating mothers in Dodota district of Arsi Zone, Oromia, Ethiopia, from February 1-28, 2021.Method: The cross-sectional study design was done on 355 lactating mothers. The starata and simple random sampling technique were used. The structured questionnaire and anthropometric measurements were used. Data were entered and cleaned using Epi info version 7.1 and SPSS version 21 for analysis. Bivariate and multivariate analysis were done. Descriptive statistics wree performed. The crude and adjusted odds ratio along with 95%CI were used to measure the strength of association. The level of statistical significance was declared at a p-value < 0.05. Result: Study revealed (14.1) lactating mother were underweight. Rural areas, (AOR=2.5 [95% CI: (1.061, 6.302), the practice of food taboos (AOR= 2.3, [95% CI: (1.045, 5.084) and income level(AOR= 2.1[95% CI: (1.003, 4. 460) were found to be independent determinants of underweight among lactating mothers in the study area. Conclusions: The prevalence of underweight among lactating mothers was lower.

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