scholarly journals Two worst pandemics- Spanish Flu and COVID-19: A review

2021 ◽  
Vol 4 (1) ◽  
pp. 001-012
Author(s):  
Varsha Dhurvey ◽  
Payal Ramteke ◽  
Rakhi Sawan ◽  
Shikha Sethiya

1918 Spanish flu and COVID-19 can be considered as most hazardous pandemics earth has ever witnessed. They are results of what mayhems an organism not even visible with naked eye can cause. Causative agent for both the diseases is a virus but, they are not same. 1918 Spanish flu gave major indications that it has the existence of the new strain of flu and lasted for longer duration affecting lives in various ways. COVID-19 is again an indication of another emerging worst pandemic. Here, we have reviewed the overall factors that contributed to the severity of these two pandemics and comparison of the same. The main motive of this paper is to put together, compare and analyze versatility of both the pandemics and to discuss implications of the same.

Diagnostics ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1038
Author(s):  
Sylvio Redanz ◽  
Andreas Enz ◽  
Andreas Podbielski ◽  
Philipp Warnke

Background: Swabbing of implants removed from potentially infected sites represents a time saving and ubiquitously applicable alternative to sonication approaches. The latter bears an elevated risk of processing related contaminations due to the high number of handling steps. Since biofilms are usually invisible to the naked eye, adequate swabbing relies on the chance of hitting the colonized area on the implant. A targeted directed swabbing approach could overcome this detriment. Method: Three dyes were tested at different concentrations for their toxicity on biofilm-associated cells of S. epidermidis, the species most frequently identified as a causative agent of implant-associated infections. Results: Malachite green (0.2%) delivered the highest bacterial recovery rates combined with the best results in biofilm visualization. Its suitability for diagnostic approaches was demonstrated for smooth and rough implant surfaces. Biofilm-covered areas were successfully visualized. Conclusion: Subsequent targeted swab-sampling resulted in a significantly increased bacterial recovery rate compared to a dye-free “random swabbing” diagnostic approach.


Author(s):  
Victor Tsutsumi ◽  
Adolfo Martinez-Palomo ◽  
Kyuichi Tanikawa

The protozoan parasite Entamoeba histolytica is the causative agent of amebiasis in man. The trophozoite or motile form is a highly dynamic and pleomorphic cell with a great capacity to destroy tissues. Moreover, the parasite has the singular ability to phagocytize a variety of different live or death cells. Phagocytosis of red blood cells by E. histolytica trophozoites is a complex phenomenon related with amebic pathogenicity and nutrition.


1995 ◽  
Vol 34 (05) ◽  
pp. 518-522 ◽  
Author(s):  
M. Bensadon ◽  
A. Strauss ◽  
R. Snacken

Abstract:Since the 1950s, national networks for the surveillance of influenza have been progressively implemented in several countries. New epidemiological arguments have triggered changes in order to increase the sensitivity of existent early warning systems and to strengthen the communications between European networks. The WHO project CARE Telematics, which collects clinical and virological data of nine national networks and sends useful information to public health administrations, is presented. From the results of the 1993-94 season, the benefits of the system are discussed. Though other telematics networks in this field already exist, it is the first time that virological data, absolutely essential for characterizing the type of an outbreak, are timely available by other countries. This argument will be decisive in case of occurrence of a new strain of virus (shift), such as the Spanish flu in 1918. Priorities are now to include other existing European surveillance networks.


EMJ Radiology ◽  
2020 ◽  
Author(s):  
Filippo Pesapane

Radiomics is a science that investigates a large number of features from medical images using data-characterisation algorithms, with the aim to analyse disease characteristics that are indistinguishable to the naked eye. Radiogenomics attempts to establish and examine the relationship between tumour genomic characteristics and their radiologic appearance. Although there is certainly a lot to learn from these relationships, one could ask the question: what is the practical significance of radiogenomic discoveries? This increasing interest in such applications inevitably raises numerous legal and ethical questions. In an environment such as the technology field, which changes quickly and unpredictably, regulations need to be timely in order to be relevant.  In this paper, issues that must be solved to make the future applications of this innovative technology safe and useful are analysed.


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