scholarly journals Gambaran Kejadian Infeksi Pada Usia Lanjut

Author(s):  
Kartika Prahasanti

ABSTRACT Infection in the elderly is the second leading cause of morbidity and death in the world after cardiovascular disease. This event is closely related to the increase in the elderly population in the last few decades caused by an increase in human life expectancy. The causes of infection in elderly due to the presence of considerable chronic comorbidities, decreased resistance or immunity to infection, decreased communication power in the elderly and difficulty recognizing signs of infection early. Infection in the elderly is not only more frequent and more severe, but also have specialties related to clinical, laboratory and microbiological presentations. The purpose of this review is to provide an overview of the predisposition of infectious diseases in the elderly, immunesenescence in the elderly, the appropriate diagnostic and treatment approach in cases of infection in the elderly.Keywords                   : infection, elderly, immunesenescence Correspondence to      : [email protected] ABSTRAK  Infeksi pada usia lanjut merupakan penyebab kesakitan dan kematian terbanyak kedua di dunia setelah penyakit kardiovaskuler. Kejadian ini berhubungan erat dengan peningkatan populasi penduduk usia lanjut pada beberapa dekade terakhir yang diakibatkan oleh peningkatan usia harapan hidup manusia. Penyebab terjadinya infeksi pada usia lanjut banyak disebabkan oleh karena adanya adanya penyakit komorbid kronik, penurunan daya tahan atau imunitas tubuh terhadap infeksi, penurunan kemampuan komunikasi pada usia lanjut sehingga jarang didapatkan keluhan serta sulitnya mengenal tanda infeksi secara dini. Infeksi pada usia lanjut tidak hanya lebih sering terjadi dan lebih berat, namun juga memiliki kekhususan terkait presentasi klinis, laboratorium maupun mikrobiologi. Tujuan dari tinjauan ini adalah untuk memberikan gambaran mengenai predisposisi penyakit infeksi pada usia lanjut, gangguan respon imun pada usia lanjut (immunesenescence), pendekatan diagnosis dan tatalaksana yang tepat pada kasus infeksi pada usia lanjut. Kata kunci                  : infeksi, usia lanjut, gangguan respon imunKorespondensi             : [email protected]

2005 ◽  
Vol 15 (2) ◽  
pp. 71-82 ◽  
Author(s):  
F Fantin ◽  
C Rajkumar ◽  
CJ Bulpitt

The elderly population has greatly increased in the last few decades as life expectancy has risen. In 2005 life expectancy at birth for females born in the UK is 80.2 years, compared with 75.2 years for males. This is in contrast to 49 and 45 years respectively in 1901. Cardiovascular disease is still the most important cause of death in the population over the age of 65, causing 40% of deaths in women and 42% in men of this age.


2010 ◽  
Vol 46 (4) ◽  
pp. 617-632 ◽  
Author(s):  
André de Oliveira Baldoni ◽  
Farah Maria Drumond Chequer ◽  
Elisa Raquel Anastácio Ferraz ◽  
Danielle Palma de Oliveira ◽  
Leonardo Régis Leira Pereira ◽  
...  

In recent decades, the world has undergone a demographic transformation with a rapid growth of the elderly population, resulting in an increased demand for funds to maintain their health and drug consumption. Pharmacokinetic and pharmacodynamic changes occurring in the elderly can interfere directly in the adverse effects of drugs and increase the risk of intoxication. In addition, there are external factors interfering with the pharmacotherapy of the elderly, such as inappropriate use and the lack of access to information. Many therapeutic classes of drugs should be used with caution or avoided in the elderly population, such as anti-inflammatory and some anti-hypertensive drugs, diuretics and digitalis. If not managed carefully, these medicines can affect the safety and quality of life in the elderly. Thus, the aim of this review was to identify drugs that should be used with caution in elderly patients in order to avoid intoxication and/or adverse drug events.


Author(s):  
В. М. Волкова ◽  
Е. И. Скирмонт ◽  
Л. М. Смирнова ◽  
С. Б. Климашева ◽  
Е. Л. Зимина ◽  
...  

По данным ВОЗ, за последнее столетие продолжительность жизни человека значительно увеличилась во всем мире, но этот процесс неизбежно сопровождается старением. Поэтому лица, достигшие пожилого и старческого возраста, нередко становятся немощными, особенно в физическом плане. В итоге, таким людям всё труднее даются движения, связанные с самообслуживанием и передвижением, при пользовании типовой одеждой и обувью. В процессе обследования 55 пациентов 60-87 лет, проведённого впервые с позиций медико-социальной реабилитации, получены данные о характере ограничений физических возможностей этого контингента людей, существенно осложняющих использование ими типовой одежды и обуви. Основной вывод работы заключается в актуальности разработки медико-технических требований, предъявляемых к проектированию и производству одежды и обуви специально для данной категории людей с учетом их измененных антропометрических параметров и характерных для них функциональных ограничений. According to the World Health Organization, human life expectancy has increased signifi cantly around the world over the past century, but this process is inevitably accompanied by aging. Therefore, persons who have reached the elderly and senile age often become infirm, especially physically. As a result, such people find it increasingly difficult to make movements related to self-service and movement when using standard clothing and shoes. In a study of 55 patients (from 60 to 87 years), conducted for the first time from the point of view of medical and social rehabilitation, data were obtained that reveal the nature of physical limitations of this group of people, which significantly complicate them use of standard clothing and shoes. The main conclusion of the work is the relevance of the development of medical and technical requirements for the design and production of clothing and footwear specifically for the elderly and senile taking into account their changed anthropometric parameters and their characteristic functional limitations.


1989 ◽  
Vol 29 (2) ◽  
pp. 95-102 ◽  
Author(s):  
Kyriakos S. Markides

Increased survival by blacks and Hispanics is causing a widening of the sex imbalance of the elderly population much like we have observed in the general population. These demographic trends point toward greater widowhood among minority women and continuing high rates of poverty. In addition, we can expect increased rates of disability in minority elderly women, increased dependency, worsening intergenerational relationships, and higher rates of institutionalization.


2018 ◽  
Vol 103 (5) ◽  
pp. 1940-1947 ◽  
Author(s):  
Ayesha Fawad ◽  
Andreas Bergmann ◽  
Joachim Struck ◽  
Peter M Nilsson ◽  
Marju Orho-Melander ◽  
...  

Abstract Context The gut hormone neurotensin promotes fat absorption, diet-induced weight gain, and liver steatosis. Its stable precursor-hormone fragment “proneurotensin” predicts cardiometabolic disease in middle-aged populations, especially in women. Objective To test if proneurotensin predicts cardiovascular disease (CVD) and diabetes development in an elderly population and whether there are gender differences in this respect. Design, Setting, and Participants Fasting proneurotensin was measured in plasma from 4804 participants (mean age 69 ± 6 years) of the Malmö Preventive Project and subjects were followed up for development of CVD and diabetes during 5.4 years. Main Outcome Measures Multivariate adjusted Cox proportional hazard models CVD were used to relate the proneurotensin to the risk of incident CVD and diabetes in all subjects and in gender-stratified analyses. Results In total, there were 456 first CVD events and 222 incident cases of diabetes. The hazard ratio [HR (95% confidence interval)] for CVD per 1 standard deviation (SD) increment of proneurotensin was 1.10 (1.01 to 1.21); P = 0.037, and the above vs below median HR was 1.27 (1.06 to 1.54); P = 0.011, with similar effect sizes in both genders. There was no significant association between proneurotensin and incident diabetes in the entire population (P = 0.52) or among men (P = 0.52). However, in women proneurotensin predicted diabetes incidence with a per 1 SD increment HR of 1.28 (1.30 to 1.59); P = 0.025 and an above vs below median HR of 1.41 (1.10 to 1.80); P = 0.007. Conclusions In the elderly population, proneurotensin independently predicts development of CVD in both genders, whereas it only predicts diabetes in women.


2021 ◽  
Vol 8 (2) ◽  
pp. 1-12
Author(s):  
Ana Glads de Queiroz Rolim ◽  
◽  
Alane Siqueira Rocha ◽  

This paper investigated depression-free life expectancy in the elderly population of Ceará, the Northeast and Brazil. We used data from the 2019 National Health Survey (PNS) and the projections of the Mortality Tables provided by the Brazilian Institute of Geography and Statistics (IBGE) in 2018. Sullivan's method was used to estimate depression-free life expectancy at age 60 years. The results show that, among the elderly in the analyzed regions, women are at a disadvantage in the number of years they will live with depression compared to men. Which suggests that women live longer with depression compared to men. Among the populations analyzed, it was also found that the one in the Northeast showed the smallest difference in the prevalence of depression in the elderly between the sexes, with 11.6% in women and 3.7% in men. In general, the Northeast has the lowest prevalence of depression among the elderly, when compared to the other two regions.


2021 ◽  
Vol 9 (8) ◽  
pp. 1733-1736
Author(s):  
Ajay Kumar Nigwal ◽  
Lajwanti Keswani ◽  
Rajesh Kumar Malviya ◽  
Arvind Kumar Yadav

Cardiovascular disease such as hypertension will be the largest cause of death and disability in India by 2020. The prevalence of hypertension is increasing globally and currently, more than 1 billion people have hypertension. About 26.4% of the world adult population in 2000 had hypertension and 29.2% were projected to have this con- dition by 2025. Elevated blood pressure affects 1 billion individuals and causes an estimated 10.4 million deaths per year. Thus, hypertension is needed to be studied. Though a lot of potent antihypertensive drugs are available today none of them is free from untoward adverse effects. Especially the elderly population poorly tolerates these drugs. The global incidence of hypertension is increasing day by day and is a very common problem nowadays. Ayurveda has classified the causes of disease into three main categories: - 1. Asatmendriyartha Samyoga 2. Pragyaparada and 3. Parinama (Kaala), these three main causes of disease enable different kinds of diseases to manifest. Firstly, they lead to the imbalance of body /or mind by vitiation the Tridosha. The consequence of the imbalance is a disturbance of the basic biological principles. Hypertension is a lifestyle disorder. Ayurveda causes of lifestyle disorders are mainly Pragyaparada. Pragyaparadha is the main cause of all noncommunicable dis- eases (NCDs) such as diabetes, cancer, hypertension etc. Keywords: Asatmendriyartha, Pragyaparada, Parinama, Trividha Rogaayatanas, Hypertension.


2020 ◽  
Vol 7 (2) ◽  
pp. 245
Author(s):  
Stephanie Elizabeth Gunawan ◽  
Anak Agung Ayu Putri Laksmidewi

Background: According to the World Health Organization (WHO), an elderly person is someone who has entered the age of 60 years and above whose percentage tends to increase along with decreasing morbidity of the elderly. Geriatric Neurology itself is the study of a group of neurological diseases in the elderly. Based on 2012 data, the proportion of elderly population in Indonesia is 7.59%. This is accompanied by an increase in the dependency ratio of the productive age population to the non-productive age population. The results of the 2013 Basic Health Research showed an increase in the prevalence of neurological disease in the elderly which was the main cause of death in 15 regencies in 2011. It is to find out the 5 most neurological diseases in the elderly, clinical characteristics and outcomes of geriatric neurology patients treated at the Central Hospital of Sanglah.Methods: It is a retrospective study using no control by looking at medical records in geriatric neurology patients aged 60 years and over who visited the Central Hospital of Sanglah in the March to May 2019 period.Results: A total of 200 patients consisted of 111 men (55.5%) and 89 women (44.5%) who were divided into 5 most geriatric neurology diseases which included 1. ischemic stroke, 2. bleeding stroke, 3. brain tumor, 4. injury head, and 5. epilepsy. The number of deaths was 16, of which 7 cases were caused by sepsis and pneumonia.Conclusions: Stroke, tumors, head injuries and epilepsy are the dominant neurological diseases found. The focus of care and supervision of elderly neurology patients is expected to be further enhanced to prevent side effects that will extend the patient’s treatment period in the hospital which will automatically increase the burden on the hospital itself.


Open Medicine ◽  
2009 ◽  
Vol 4 (2) ◽  
pp. 171-178
Author(s):  
Yasar Kucukardali ◽  
Oral Oncul ◽  
Erdogan Kunter ◽  
Vedat Turhan ◽  
Emrullah Solmazgul ◽  
...  

AbstractIn geriatric practice, data regarding infections including the epidemiology, morbidity, and mortality are lacking. Our aim was to evaluate the frequency, location, microbiological and laboratory characteristics of infectious diseases in elderly population admitted to a training hospital. The patients were included total of 330 patients, aged over 65 with infection, seen between January 1, 2005 and January 1, 2006. In the result, of patients 136 (41%) had respiratory system infection, 90 (27%) urinary system infection, 39 (12%) gastrointestinal system infection, 34 (10%) bloodstream infections, 17 (5%) soft tissue infection, 8 (2%) central nervous system infections, and 6 (2%) others. Average length of hospitalization was 8.6±7.7 days. Mortality rate from all causes was 57 (17%). The most common infections in elderly patients were respiratory tract and urinary system infections, and there were no fever, leukocytes and high CRP levels in approximately 1/3 of cases. Infectious diseases may occur even in the absence of such infection indicators as fever, raised WBC count and high CRP level in the elderly population.


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