scholarly journals Uterine leiomyoma in women of reproductive age: pregnancy and childbirth management (Literature review)

2021 ◽  
Vol 3 ◽  
pp. 48-56
Author(s):  
О.V. Golyanovskiy ◽  
K.V. Supruniuk ◽  
S.V. Frolov
Keyword(s):  
Adverse Effect ◽  
Surgical Treatment ◽  
Literature Review ◽  
Uterine Leiomyoma ◽  
Reproductive Age ◽  
Insufficient Data ◽  
Women Of Reproductive Age ◽  
Pregnancy And Childbirth ◽  
Management Literature ◽  
Accurate Indicator

The article presents a review of the current literature on the problem of uterine leiomyoma (UL) in women of reproductive age during pregnancy and childbirth. We studied the main issues of uterine leiomyoma etiology and pathogenesis, as one of the leading causes of reproductive dysfunction and possible complications during pregnancy and childbirth.UL is the most common tumor of the female genitalia and occurs in 20–30% of women of reproductive age. It is impossible to determine a more accurate indicator of this pathology, given the asymptomatic course of more than 70% of cases and irregular consultations by obstetricians and gynecologists.There is evidence that uterine leiomyoma is associated with infertility in only 5–10% of cases, but only 2–3% of cases when all other causes are ruled out. The submucosal node has the most adverse effect on fertility and reduces the implantation frequency by 72% and increases the miscarriage risk by 60%. Subserous LM affects fertility to a lesser extent than submucosal LM, but large nodules can lead to infertility requiring surgical treatment. An individual approach to the treatment of women with intramural LM is required, as there is insufficient data on the node effect on fertility.The most common complications of pregnancy, childbirth and the postpartum period in women with uterine leiomyoma in 22–58% of cases are late preeclampsia, fetoplacental insufficiency, anemia of pregnancy, fetal growth restriction, incorrect position and presentation of the fetus. Pregnancy also adversely affects UL, leading to acute secondary changes and rapid tumor growth, which in turn can lead to severe obstetric complications.

scholarly journals Characteristics of Uterine Hyperplastic Processes in Women with Obesity

2016 ◽  
Vol 23 (3) ◽  
Author(s):  
O. M. Makarchuk ◽  
Abdulrakhman Abdulbaset Moslem
Keyword(s):  
Uterine Leiomyoma ◽  
Metabolic Disorders ◽  
Significant Risk ◽  
Reproductive Age ◽  
Sexual Disorders ◽  
Control Group ◽  
Histological Structure ◽  
Obese Women ◽  
Women Of Reproductive Age ◽  
Endometrial Polyps

Introduction. Analysis of uterine leiomyoma incidence indicates not only its growth but also the increase in the number of women of early reproductive age. However, the problem of trigger mechanisms for its development is still uncertain and actual.The objective of the research was to assess the characteristic features of hyperplastic processes in uterus on the background of dishormonal and metabolic disorders.Materials and methods. 60 women of reproductive age with uterine leiomyoma participated in the clinical trial. They gave their informed written consent. The control group consisted of 20 healthy women of reproductive age. Statistical analysis was conducted using material package “STATISTICA for Windows®-6.0” and methods of odds ratio (OR) calculating and its 95% Confidential Interval (95% CI).Results and their discussion. According to the results of the research the main factors contributing to uterine fibroid development in women with obesity were determined. They included: the age of 30-45 years, instrumental intervention in the womb (abortion, diagnostic curettage, etc. (OR = 8.2; 95% CI: 5.1-13.5)); chronic inflammatory diseases of genitalia (OR = 7.9; 2.9-21.9); hormonal imbalances (fibro-cystic breast disease, thyroid disorders (OR = 8.61; 3.1-23.8), liver and gastrointestinal tract disorders (OR = 5.8; 2.1-15.9) sexual disorders and stress inductive factors (OR = 2.6; 1.4-7.1) (usually fibroids occur in 1-2 years after severe stress). There is a significant percentage of adenomyosis and endometrial hyperplastic processes. Growth of tumors in women with obesity increases to 35-40 years of age, and is associated not only with a progressive decrease in the functional activity of the ovaries, their sensitivity to gonadotrophic stimulation, but also with chronic functional exertion of regulation systems on the background of metabolic disorders of hemostasis and homeostasis in this category of women.Conclusions. One of the most significant risk factors for hyperplastic processes of the reproductive organs is obesity and associated metabolic disorders. In case of metabolic disorders activity and hepatocytes on the background of obesity the number of combined forms of hyperplastic processes in the uterus increases by 1.9 times. The main risk factor for fibroids in obese women is hepatocytes dysfunction on the background of a high percentage of hepatobiliary pathology, endocrine pathology – 68.3% (thyroid dysfunction, fibro-cystic breast changes). Morphological and histological structure of endometrium in obese women leads to the growth of endometrial polyps (36.66%).

scholarly journals Experience of treatment of endometriosisrelated pneumothorax

2017 ◽  
Vol 176 (3) ◽  
pp. 56-60
Author(s):  
V. G. Pishchik ◽  
A. D. Obornev ◽  
M. A. Atyukov ◽  
A. S. Petrov ◽  
A. I. Kovalenko
Keyword(s):  
Surgical Treatment ◽  
Hormone Therapy ◽  
Spontaneous Pneumothorax ◽  
Pleural Cavity ◽  
Reproductive Age ◽  
Control Group ◽  
Visual Examination ◽  
Women Of Reproductive Age ◽  
Course Of Disease

OBJECTIVE. The article analyzed the experience of treatment of endometriosis-related pneumothorax (ERP). MATERIAL AND METHODS. The diagnosis of ERP was detected in 30 women at the period from 2004 to 2015. A control group consisted of 149 women. RESULTS. Statistically significant differences associated with presence of ERP were the elder age, right-side localization and recurrence course of disease. Diaphragmatic fenestrations and endometriotic ectopy and their combinations were specific findings in ERP-group. This group of patients characterized by frequent recurrences and higher rate of complications. The most effective method of treatment of ERP was diaphragm resection with pleurectomy and hormone therapy from 3 to 6 months after surgery. CONCLUSIONS. Endometriosis-related pneumothorax could cause up to 34 % cases of spontaneous pneumothorax in women of reproductive age. Diaphragmatic fenestrations and endometriotic lesions were specific signs of EAP. Direct visual examination of the pleural cavity was inevitable for reliable diagnostics of the disease. Surgical treatment of ERP was determined by higher rates of complication and recurrence. Postoperative hormone therapy could significantly improve the results of surgical treatment of ERP.

scholarly journals Umbilical Nodule with Cyclical Bleeding: A Case Report and Literature Review of Atypical Endometriosis

2016 ◽  
Vol 2016 ◽  
pp. 1-6
Author(s):  
Marlene Teixeira Andrade ◽  
Cláudia V. Marques de Freitas ◽  
Sara Filipa Camacho Câmara ◽  
José Joaquim Nunes Vieira
Keyword(s):  
Case Report ◽  
Laparoscopic Surgery ◽  
Literature Review ◽  
Medical History ◽  
Surgical Resection ◽  
Diagnostic Tests ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Atypical Endometriosis ◽  
Umbilical Endometriosis

Endometriosis is defined as the presence of endometrial glands and stroma outside the uterus. It affects 3 to 10 percent of women of reproductive age. Umbilical endometriosis is rare, with an estimated incidence of 0.5–1.0% among all cases of endometriosis, and is usually secondary to prior laparoscopic surgery involving the umbilicus. In this report, we described a case of umbilical endometriosis treated with surgical resection and highlight the great importance of medical history compared to complementary diagnostic tests that can be sometimes inconclusive.

scholarly journals Development process of the preconception education booklet

2021 ◽  
Author(s):  
Siti Nurunniyah ◽  
Detty Siti Nurdiati ◽  
Madarina Julia ◽  
Hamam Hadi
Keyword(s):  
Health Care ◽  
Focus Group ◽  
Literature Review ◽  
Health Care Workers ◽  
Health Workers ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Response Test ◽  
Expert Review ◽  
Care Workers

Background: Healthy preconception is very essential to prepare for pregnancy, childbirth, and healthy babies. However, many women still lack of knowledge on having healthy preconceptions. Effective education requires relevant and standardized material and educational media. The objective of this study aimed to explain the process of developing a preconception education booklet.Methods: We have developed a preconception education booklet. The method to develop this booklet involved five main stages: literature review, interviews with preconception women and health care workers in primary health care, focus group discussions with the lecturer of midwifery, nutrition, and health promotion, expert review, and measure response test from women of reproductive age.Results: Our literature review has come out with a summary of the preconception educational materials consist of 15 topics that have been present. By using In-depth interviews, we observed and then developed materials that were required by women of reproductive age and health workers and they consisted of 10 topics. Our Focus Group Discussion has come out with the need to grouping the materials into 4 groups (pillars). We then validated our booklet material by using Expert review. Finally, our response test showed that 96% of respondents agree that booklet material is easy to understand, 90% of respondents agree that booklets are interesting to read, 93% of respondents agree that booklet material is relevant to their condition, 90% of respondents agree that the material in the booklet is the material it needs, 86% of respondents agree that the material in this booklet can help with their health problems, 80% of respondents agree that the choice of words in the booklet is easy to understand, 90% of respondents agree that the cover of the booklet is very interesting, 100 respondents agree that the font of the letters in the booklet is easy to read, 80% of respondents agreed that the illustrations relevant with the materials. Booklets were positively appreciated by 87% (26 out of 30 respondents) of reproductive-age women.Conclusions: Our preconception booklet can be used by health care workers to provide pregnancy preparation counselling for women of reproductive age.

scholarly journals POLYCYSTIC OVARIAN DISEASE

2006 ◽  
Vol 13 (02) ◽  
pp. 186-191
Author(s):  
SHAHID IRSHAD RAO ◽  
HINA KOKAB ◽  
RASHIDA SADIQ
Keyword(s):  
Surgical Treatment ◽  
Sample Size ◽  
Clomiphene Citrate ◽  
Reproductive Age ◽  
Gnrh Analogue ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Polycystic Ovarian Disease ◽  
Ovarian Disease ◽  
Us Scan

Introduction: Poly Cystic Ovarian Disease (PCOD) is probably one of the most commonendocrinological disorders amongst the women during their reproductive years. Using USG criteria only 20-33% ofapparently healthy women in childbearing period, have been found to have PCOD in population study. Whereasprevalence of 4-10% in women of reproductive age is commonly reported when the diagnosis is based on clinical,biochemical and US scan features. Objective:-Diagnosis and management of polycystic ovarian disease. Setting SeyalMedical Centre, Multan. Duration From January 2002 to December 2003. Material and Methods: Sample size: 200patients. Results: Most of he patients were in the age group of 21-30 years. The youngest patient was of 17 years andeldest was of 42 years. Majority of the women were nulliparous or of low parity comprising 92% of cases. Thecommonest symptom was menstrual disorder in 168 Patients (84%). Ultrasound is very helpful for diagnosis of POD.About 80% of patients were diagnosed as PCOD on ultrasound. There is increased level of LH in 72% patients, 8%have raised prolactin levels. All patients were first treated with clomiphene citrate while surgical treatment is done inonly 30% of cases. GnRH analogue and purified FSH were not used because they are quite expensive. Conclusion:PCOD is found to be one of the commonest problem in reproductive years of life. Clomiphene citrate is first linetreatment in PCOD for infertility. Laparoscopic drilling has very good results especially in clomiphene resistant cases.

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