scholarly journals Analysis of the Influence of Risk Factors of Type 2 DM on Outpatients at DKT Bandar Hospital Lampung, 2020

2021 ◽  
Vol 4 (2) ◽  
pp. 4-14
Author(s):  
Feby Esmiralda ◽  
Aila Karyus ◽  
Kodrat Pramudho

DM is a chronic metabolic disease characterized by hyperglycemia and cause serious complications with an increasing prevalence rate. Control of risk factors that affect the incidence of DM is needed to prevent the emergence of DM and delay disease complications. The purpose of this study is to determine the risk factors that influence the incidence of type 2 diabetes outpatients at the DKT Bandar Lampung Hospital. This type of research is quantitative observational analytic with a case control approach. The population came from all patients undergoing outpatient treatment at the Internal Medicine Department of the DKT Hospital in Bandar Lampung with 44 case samples and 44 control samples. Data analysis used univariate analysis with percentages, bivariate analysis with Chi Square and multivariate analysis with multiple logistic regression. The results showed that there was a significant influence between the risk factors for age (p value 0.017), hereditary history of diabetes (p value 0.03), physical activity (p value 0.002) and obesity (p value 0.001) with the incidence of type 2 diabetes, while a history of hypertension has no effect on the incidence of type 2 diabetes mellitus (p value 0.135). Meanwhile, the most dominant variable influencing the incidence of outpatient type 2 diabetes mellitus at DKT Bandar Lampung Hospital is physical activity with OR 5.29. Maximum promotive, preventive, curative and rehabilitative efforts are needed to control risk factors for type 2 diabetes

Author(s):  
Shakthinag S ◽  
Sandip Sardessai

Background: With the heritability of Type 2 diabetes mellitus adding to the disease burden, it would be ideal to find screening tools to detect early changes that could be present in Euglycemic individuals with a genetic predisposition. Objective: To study if the parental history of type 2 diabetes mellitus has an association with the time domain, frequency domain and nonlinear basal heart rate variability indices Methods and material: Thiscross sectional study was conducted in the Physiology department of Goa Medical college over a period of 2 months on 70 Medical students between the age of 18-21 years, with low-moderate stress (PAS 10) and fair physical activity(PAI of American academy of health and fitness). Using an Inco Polyrite D instrument, data collection was done and the RR interval data was analysed using Kubios software for the basal Heart rate variability indices of time domain, frequency domain and nonlinear methods. Data was entered into Excel spreadsheet and analysed using SPSS version 14. Mann Whitney U test was done to test for statistical significance. Result: The mean age of the sample was 18.94± 0.759 years and out of the 70 subjects who had participated in the study 36 (51.4%) subjects had a positive parental family history of type 2 diabetes mellitus while 34 (48.6%) subjects did not. Significant changes were observed in the LF (nu), HF (nu) and LF/HF ratio. A significantly higher LF.n.u (p value - 0,008) and LF/HF (p value- 0.008) was observed in group with family history and a significantly lower HF.n.u ( p value – 0.007)was observed in the same group. No other significant changes were observed in time domain and non linear indices. Conclusion: Frequency domain HRV may be useful as a predictive index for diabetes mellitus. The presence of higher sympathetic activity and lower parasympathetic activity in individuals (with comparable stress level, BMI, physical activity) having a positive parental history of diabetes mellitus might indicate an underlying autonomic imbalance Keywords: Diabetes, Family history, Heart rate variability, HRV, parental history, Sympathovagal balance


2020 ◽  
Vol 15 (1) ◽  
pp. 267-273
Author(s):  
Jingjing Guo ◽  
Bin Wang ◽  
Weikai Hou ◽  
Kun Ma

AbstractThe study aims to examine the risk factors for increased colorectal cancer (CRC) markers in patients with type 2 diabetes mellitus (T2DM). The 229 patients retrospectively reviewed were categorized into two groups: CRC tumor marker-positive and -negative groups. Patients who tested positive for all three of the following CRC markers were included in the CRC tumor marker-positive group: serum carcinoembryonic antigen, carbohydrate antigen 19-9 and septin9 methylation. Univariate analysis revealed that most CRC marker-positive patients had higher age, a family history of CRC, history of smoking and alcohol intake, high body mass index (BMI; overweight), longer history of T2DM, worse diabetes control (with high glycated hemoglobin A1c [HbA1c]), lower level of serum vitamin D (VD), high-density lipoprotein cholesterol and higher level of total cholesterol and triglyceride (TG). Logistic regression analysis showed that BMI, VD, HbA1c and TG were independent predictors of CRC marker-positive status (OR, 95% confidence intervals and P values were 1.912 [1.346–2.716], <0.001; 0.773 [0.633–0.943], 0.011; 9.082 [3.52–23.433], <0.001; and 11.597 [3.267–41.164], <0.001, respectively). In this retrospective study, high BMI, HbA1c and TG as well as low level of VD were correlated with CRC tumor marker-positive status in T2DM patients. Patients with these risk factors may benefit from more frequent screening for CRC tumor markers.


2017 ◽  
Vol 6 (4) ◽  
Author(s):  
Ninna Rohmawati

Education and eating pattern has significant contributions in determining incident of Diabetes Mellitus. Based on Riskesdas 2013, patient of Diabetes Mellitus who age >15 years increased from 5.7% (2007) to 6.9% (2013). Prevalence of Diabetes Mellitus in east java diagnosed by a doctor at 2.1%. The aim to determine risk factors affecting Diabetes Mellitus. This research was observational study. Subjects were patient of type 2 Diabetes Mellitus in RSD Kalisat who fulfilled inclusion criteria. Research subjects consisted of 40 people. Risk factors patients type 2 diabetes mellitus in the work area of Kalisat hospital Jember regency was in majority 45 years (82.5%), female (62.5%), basic education (77.5%), low levels of knowledge (47.5%), housewives 45%, eating pattern (87.5%), less sport activity (67.5%), less physical activity (55% ), overweight (37.5%) and not have the acts of hypertension (55%). Advice: education relation to knowledge needs to be improved, have good eating pattern, and need for regular physical activity.


Author(s):  
Gopalakrishnan S. ◽  
Rama R. ◽  
Muthulakshmi M.

Background: Prevalence of type 2 diabetes mellitus [T2DM] is becoming alarmingly high among younger age groups impacting on their physical, mental, social and academic wellbeing and therefore warrants early detection and prevention. The Indian diabetes risk score [IDRS] is an efficient screening tool to detect the high risk individuals at an early stage. Objective of this study is to assess the level of risk of developing T2DM among medical students using the IDRS.Methods: This cross sectional study was done using the MDRF-IDR Score to identify the ‘at risk’ medical students. Simple random sampling was used and data collected from among the 251 willing students. Their risk score was calculated using a structured questionnaire. Data was analysed using SPSS Ver.15 software.Results: This study shows that about 57.4% are moderately at risk and 2% are at high risk for developing diabetes mellitus. About 86.1% medical students belonged to nuclear family, 42.6% had family history of diabetes mellitus, 76.5% carried out moderate physical activity and 50.2% were overweight / obese. Family history of diabetes, lack of physical activity and overweight / obesity were found to be potential risk factors for developing diabetes mellitus (p<0.0001).Conclusions: This study reveals that in the existing urban lifestyle, adolescents and youths are highly vulnerable to diabetes mellitus. Primordial and primary prevention are the most effective preventive measure and therefore, appropriate and stringent lifestyle modifications need to be implemented in order to minimize the risk of developing the disease later in life.


2020 ◽  
Vol 6 (4) ◽  
pp. 182
Author(s):  
Maulidia Ekaputri ◽  
Henrico Citrawijaya ◽  
Kevin Jonathan Adhimulia ◽  
Adrian Reynaldo Sudirman ◽  
Radityo Ali Murti ◽  
...  

Pendahuluan. Pasien diabetes melitus tipe 2 (DMT2) pada umumnya memiliki satu atau lebih komplikasi kronik pada saat terdiagnosis. Deteksi dini dan pencegahan sangat penting untuk mengurangi angka mortalitas dan morbiditas terkait DMT2, terutama pada kelompok dengan risiko tinggi seperti anak penderita DMT2. Studi ini bertujuan untuk mencari faktor-faktor yang berkaitan dengan status prediabetes pada anak dari penderita diabetes melitus tipe 2.Metode. Studi ini merupakan studi potong lintang yang melibatkan 54 anak dari penderita DMT2. Subjek dikumpulkan secara konsekutif. Status prediabetes ditentukan melalui HbA1C berstandar national glycohemoglobin standardization program (NGSP). Aktivitas fisik ditentukan melalui kuisioner global physical activity questionnaire (GPAQ)-versi Bahasa Indonesia. Tekanan darah dan data antropometrik diukur secara langsung. Analisis bivariat dan multivariat dilakukan dengan IBM SPSS 23.Hasil. Dilakukan analisis terhadap 54 subjek. Mayoritas subjek adalah perempuan (79,6%) dan rerata umur adalah 38,8 tahun. Proporsi prediabetes mencapai 31,5%. Analisis multiavariat menunjukkan hubungan bermakna antara riwayat paternal DMT2 (adjusted OR 7,520; IK 95%=1,071-52,784), lingkar pinggang berisiko (adjusted OR 5,482; IK 95%=1,019-29,504) terhadap status prediabetes.Simpulan. Riwayat paternal DMT2 dan lingkar pinggang berkaitan dengan status prediabetes pada anak dari penderita DMT2.Kata Kunci: Anak penderita DM tipe 2, HbA1C, intoleransi glukosa, prediabetes The Role of Paternal History of Type 2 Diabetes Mellitus on Prediabetes Status among The Offspring of Type 2 Diabetes Mellitus Patients Introduction. Since patients with type 2 diabetes mellitus (T2DM) often present with one or more chronic complications, at the time of diagnosis, early detection and prevention is essential to reduce T2DM-associated mortality and morbidity, espescially among high risk population such as the offspring of T2DM. This study aimed to investigate several factors associated with prediabetes status among the offsprings of T2DM patients.Methods. A cross-sectional study was conducted involving 54 offsprings of T2DM patients. Subjects were recruited consecutively. We collected demographic data, anthropometric measurement, blood pressure, and HbA1c level. Physical activity were assessed by using Indonesian version of global physical activity questionnaire (GPAQ). Prediabetes status was investigated by standardized national glycohemoglobin standardization program (NGSP) HbA1c. Bivariate statistical and multivariate analysis was performed by using IBM SPSS 23.Results: The majority of subjects were female (79.6%) and the mean age was 38.8 years old. The proportion of prediabetes was 31.5%. Multivariate analysis showed significant association among paternal history of T2DM (adjusted OR 7.520; 95%CI=1.071-52.784), waist circumference at risk (adjusted OR 5.482; 95%CI=1.019-29.504), and prediabetes status.Conclusion: Paternal history of T2DM and waist circumference were associated with prediabetes status among the offspring of T2DM patients.


2017 ◽  
Vol 20 (4) ◽  
pp. 4-10
Author(s):  
Tatiana Olegovna Yalochkina ◽  
Janna Evgen'evna Belaya ◽  
Lyudmila Yakovlevna Rozhinskaya ◽  
Michail Borisovich Antsiferov ◽  
Larisa Konstantinovna Dzeranova ◽  
...  

Aim. To estimate the prevalence of and risk factors for low-traumatic fractures in patients with type 2 diabetes mellitus (T2DM).Materials and methods. We questioned 214 patients with T2DM from a single outpatient clinic located in Moscow to evaluate the prevalence of and risk factors for low-traumatic fractures, the duration of and complications from TD2M and HbA1c levels.Results. Of 214 patients, 65 reported low-traumatic bone fractures. Patients with a history of low-traumatic fractures reported falls in the previous year (28%), whereas only 13% of patients without fractures reported falls. The difference was statistically significant, with an odds ratio of 2.34 (1,144,76), P=0,022. Men reported fractures more frequently than women (43.3% vs. 24.7%, respectively, P = 0.01). Patients with bone fractures had a lower body mass index (P = 0.022); however, a multivariate analysis revealed that a history of falls and male sex were the most significant risk factors for fracture.Conclusion. Around 30% of patients with T2DM from a Moscow outpatient clinic reported bone fractures. The most significant risk factors for fracture were a history of falls in the previous year and male sex. The article is the RePrint from the original article inDiabetes Mellitus (2016); 19(5) pp. 359-365. doi: 10.14341/DM7796


2021 ◽  
Vol 9 (2) ◽  
pp. 151
Author(s):  
Nissa Kusariana ◽  
Tutut Okta Hardiyanti ◽  
Moh. Arie Wurjanto

Background: Diabetes mellitus is a non-communicable disease that can be prevented by controlling the risk factors. Diabetes mellitus prevention practice is important so that prevention of type 2 diabetes mellitus can be carried out effectively. There are several factors that cause a person to practice prevention against diabetes mellitus. Objective: This study aims to analyze factors related to the practice of type 2 diabetes mellitus prevention among Diponegoro University students in Semarang. Methods: This is a quantitative study with an observational analytic approach and a cross-sectional study design. The time of research was May-August 2020. The instrument in this study was a google form questionnaire. The population in this study were active undergraduate students of Diponegoro University in 2020, amounting to 36,425 students. The sample size in this study was 407 respondents. The variables of the study were family history of type 2 diabetes mellitus, knowledge level, attitude, family support, and preventive practices of type 2 diabetes mellitus. This study used univariate analysis and bivariate analysis. The relationship test was performed using the chi-square test on a computer application. Results: This study showed there was a significant relationship between family history type 2 diabetes mellitus (0,017), knowledge level (0,00), attitude (0,00), and family support (0,00) for the preventive practices of type 2 diabetes mellitus in students. Conclusion: Family history of type 2 diabetes mellitus, knowledge level, attitude, and family support are factors related to the preventive practices of type 2 diabetes mellitus among students of Diponegoro University in Semarang. There is a need for education and provision of information related to knowledge on diabetes mellitus prevention for students at Diponegoro University, Semarang.


2019 ◽  
Vol 1 (2) ◽  
pp. 77-83 ◽  
Author(s):  
Bikash Shrestha ◽  
Bipin Nepal ◽  
Yagya Laxmi Shakya ◽  
Binaya Regmi

 Introduction: Type 2 diabetes mellitus is the commonest form of diabetes affecting more than 90% of the diabetic population worldwide. The prevalence of type 2 diabetes and its complications are increasing in the world, including developing nations like Nepal. This study aimed to determine the association between the lifestyle risk factors and the risk of type 2 diabetes mellitus in Nepalese population. Methods: This is hospital based cross sectional observational study done in the urban area of Nepal. Records of clients coming for the general health checkup in Grande International Hospital were evaluated in this study. Comparisons of the lifestyle factors in participants having and not having type 2 diabetes mellitus were done. Results: Significant associations with diagnosis of diabetes mellitus (DM) type 2 were seen in age (P ≤ 0.001), associated hypertension (P ≤ 0.001), dyslipidemia, family history of DM (P ≤ 0.001), alcohol use (P ≤ 0.001), and tobacco use (P ≤ 0.001). Logistic regression analysis showed that the odds of having diabetes were high in age group above 40 (OR – 6.9, CI 3.82 – 12.47), history of hypertension (OR- 3.84, CI 2.42 – 6.08), tobacco users (OR-2.26, CI 1.12 – 4.53), alcohol users (OR-3.99, CI 2.47 – 6.44), family history of DM (OR-2.44, CI 1.53 – 3.89), and abdominal obesity in both males (OR-3.9, CI 2 – 7.4) and females (OR-9.6, CI 3.78 – 24.35). Conclusions: The modifiable risk factors - obesity, smoking and alcohol use carry significant risks of developing type 2 diabetes. These red flag signs call for urgent attention to look for and rectify the modifiable risk factors in Nepalese population to prevent diabetes.


Author(s):  
Felipe De la Fuente ◽  
María Angélica Saldías ◽  
Camila Cubillos ◽  
Gabriela Mery ◽  
Daniela Carvajal ◽  
...  

Type 2 diabetes mellitus (T2DM) is a public health challenge that must be addressed considering the large number of risk factors involved in its appearance. Some environmental risk factors are currently described as predictors of diabetes, with access to green spaces being an element to consider in urban settings. This review aims to study the association between exposure to green spaces and outcomes such as diabetes, obesity, and physical activity in the general population. A systematic review was carried out using the PubMed, Embase, and LILACS databases and other sources. The search strategy was carried out from October 2019 to October 2020. Cross-sectional and cohort studies were included. The article selection was made by a pair of reviewers, and data extraction was carried out using a data extraction sheet. The quality assessment of the included studies was carried out using a validated tool. Finally, 19 scientific articles were included in this review. Evidence supports that people and communities exposed to green spaces, especially in their neighborhood, reduce the risk of T2DM and reduce the risk of being obese and increase the likelihood of physical activity. The onset of T2DM can be moderated by using green spaces, improving physical activity levels, and reducing the risk of being overweight and obese.


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