scholarly journals MICROMORPHOLOGY OF TEGUMENT OF EURYTREMA PANCREATICUM BEFORE AND AFTER ANTHELMINTICS

2021 ◽  
pp. 85-90
Author(s):  
Bibik ◽  
Nacheva ◽  
Nesterok
Keyword(s):  
Outer Part ◽  
Expert Assessment ◽  
Control Group ◽  
Comparative Effect ◽  
Comparative Aspect ◽  
Before And After ◽  
After Effect ◽  
Outer Cover ◽  
The One

The article describes micromorphological features of the tegument of the trematode of the species Eurytrema pancreaticum (Janson, 1899), Loos, 1907, family Dicrocoelliidae Odhner, 1911. The parasites were collected by dissection of spontaneously infected animals (cattle) with Eurytrema and with formed chronic eurythrematosis. Some of the trematodes were collected from the control group of animals, and some after deworming with anthelmintics. Using histological methods in a comparative aspect with the control, changes in the morphological features of the tegument of Eurytrema after effect of hexachloroparaxylol and oxinid were shown. It has been established that the toxic effect of anthelmintics causes destruction of the tegument. This increases the permeability of the drug and its metabolites through the outer cover of the trematodes into their body. There is a complete atrophy of the outer part of the tegument, and in the inner part of the tegument there is a decrease in the number of degenerative cells with hexachloroparaxylol and their increase with oxinid. The comparative effect by two anthelmintics of the old generation on the tegument is described to emphasize the effectiveness of their use in trematodiases, on the one hand, and to show the quality of histological methods in the expert assessment of drugs, on the other.

scholarly journals Real-World Experience of the One-Year Efficacy of Rifaximin Add-On to Lactulose Is Superior to Lactulose Alone in Patients with Cirrhosis Complicated with Recurrent Hepatic Encephalopathy in Taiwan

2021 ◽  
Vol 11 (6) ◽  
pp. 478
Author(s):  
Ching Chang ◽  
Chien-Hao Huang ◽  
Hsiao-Jung Tseng ◽  
Fang-Chen Yang ◽  
Rong-Nan Chien
Keyword(s):  
Hepatic Encephalopathy ◽  
Real World ◽  
Ammonia Level ◽  
Decompensated Cirrhosis ◽  
Control Group ◽  
Multivariable Logistic Regression Model ◽  
Before And After ◽  
One Year ◽  
The One ◽  
Serum Ammonia

Background: Hepatic encephalopathy (HE), a neuropsychiatric complication of decompensated cirrhosis, is associated with high mortality and high risk of recurrence. Rifaximin add-on to lactulose for 3 to 6 months is recommended for the prevention of recurrent episodes of HE after the second episode. However, whether the combination for more than 6 months is superior to lactulose alone in the maintenance of HE remission is less evident. Therefore, the aim of this study is to evaluate the one-year efficacy of rifaximin add-on to lactulose for the maintenance of HE remission in Taiwan. Methods: We conducted a real-world single-center retrospective cohort study to compare the long-term efficacy of rifaximin add-on to lactulose (group R + L) versus lactulose alone (group L, control group). Furthermore, the treatment efficacy before and after rifaximin add-on to lactulose was also analyzed. The primary endpoint of our study was time to first HE recurrence (Conn score ≥ 2). All patients were followed up every three months until death, and censored at one year if still alive. Results and Conclusions: 12 patients were enrolled in group R + L. Another 31 patients were stratified into group L. Sex, comorbidity, ammonia level, and ascites grade were matched while age, HE grade, and model for end-stage liver disease (MELD) score were adjusted in the multivariable logistic regression model. Compared with group L, significant improvement in the maintenance of HE remission and decreased episodes and days of HE-related hospitalizations were demonstrated in group R + L. The serum ammonia levels were significantly lower at the 3rd and 6th month in group 1. Concerning changes before and after rifaximin add-on in group R + L, mini-mental status examination (MMSE), episodes of hospitalization, and variceal bleeding also improved at 6 and 12 months. Days of hospitalization, serum ammonia levels also improved at 6th month. Except for concern over price, no patients discontinued rifaximin due to adverse events or complications. The above results provide evidence for the one-year use of rifaximin add-on to lactulose in reducing HE recurrence and HE-related hospitalization for patients with decompensated cirrhosis.

scholarly journals Robot-Assisted Gait Training in Patients with Multiple Sclerosis: A Randomized Controlled Crossover Trial

Medicina ◽  
2021 ◽  
Vol 57 (7) ◽  
pp. 713
Author(s):  
Cristiano Sconza ◽  
Francesco Negrini ◽  
Berardo Di Matteo ◽  
Alberto Borboni ◽  
Gennaro Boccia ◽  
...  
Keyword(s):  
Crossover Trial ◽  
Gait Training ◽  
Treatment Session ◽  
Control Group ◽  
Walk Test ◽  
Robot Assisted ◽  
Randomized Controlled ◽  
Gait Parameters ◽  
Before And After

Background and Objectives: Gait disorders represent one of the most disabling aspects in multiple sclerosis (MS) that strongly influence patient quality of life. The improvement of walking ability is a primary goal for rehabilitation treatment. The aim of this study is to evaluate the effectiveness of robot-assisted gait training (RAGT) in association with physiotherapy treatment in patients affected by MS in comparison with ground conventional gait training. Study design: Randomized controlled crossover trial. Materials and Methods: Twenty-seven participants affected by MS with EDSS scores between 3.5 and 7 were enrolled, of whom seventeen completed the study. They received five training sessions per week over five weeks of conventional gait training with (experimental group) or without (control group) the inclusion of RAGT. The patients were prospectively evaluated before and after the first treatment session and, after the crossover phase, before and after the second treatment session. The evaluation was based on the 25-foot walk test (25FW, main outcome), 6 min walk test (6MWT), Tinetti Test, Modified Ashworth Scale, and modified Motricity Index for lower limbs. We also measured disability parameters using Functional Independence Measure and Quality of Life Index, and instrumental kinematic and gait parameters: knee extensor strength, double-time support, step length ratio; 17 patients reached the final evaluation. Results: Both groups significantly improved on gait parameters, motor abilities, and autonomy recovery in daily living activities with generally better results of RAGT over control treatment. In particular, the RAGT group improved more than control group in the 25FW (p = 0.004) and the 6MWT (p = 0.022). Conclusions: RAGT is a valid treatment option that in association with physiotherapy could induce positive effects in MS-correlated gait disorders. Our results showed greater effectiveness in recovering gait speed and resistance than conventional gait training.

MEASURES FOR IMPROVING THE MICROBIOLOGICAL SAFETY OF COW MILK

2019 ◽  
Vol 1 (1) ◽  
pp. 44-49
Author(s):  
G. A. Larionov ◽  
◽  
O. Yu. Checheneshkina ◽  
N. V. Mardaryeva ◽  
N. V. Sсhiptsova ◽  
...  
Keyword(s):  
Somatic Cells ◽  
Research Work ◽  
Dairy Farm ◽  
Cow Milk ◽  
Control Group ◽  
Anaerobic Microorganisms ◽  
Special Means ◽  
Before And After ◽  
Processing Enterprise

Safety of milk on microbiological indicators is an important condition for acceptance on the milk processing enterprise. High microbial contamination of milk and increased content of somatic cells in milk are often the cause of discrepancy to modern requirements of national and international regulatory documents. The development and implementation of measures aimed at improving the condition of the udder of cows, the use of modern means of processing is one of the most important tasks to improve the sanitary and hygienic conditions of milk production. Prevention of mastitis is one of the effective ways to improve the safety and quality of cows' milk. It is known that the most affordable way to prevent mastitis is strict hygiene during milking. In our article the results of research work received in the conditions of a dairy farm are presented. Researches on use of modern domestic means of processing of an udder before and after milking are carried out. For this, two experimental and one control groups were created. In summer and autumn, the udder of cows in the experimental groups were treated with special detergents and disinfectants. In the control group, the udders were not treated with special means. Udder hygiene was maintained by washing the nipples with warm water, as is customary in the household. It was established that the treatment of the udder of cows with disinfectants decreased the number of mesophilic aerobic and facultatively anaerobic microorganisms and somatic cells in the milk of cows.

The effects of breathing exercises on respiratory functions, functional capacity and quality of life in vehicle spray painters

2021 ◽  
Vol 28 (12) ◽  
pp. 1-8
Author(s):  
Burak Yilmaz ◽  
Cagtay Maden ◽  
Begümhan Turhan
Keyword(s):  
Quality Of Life ◽  
Functional Capacity ◽  
Control Group ◽  
Study Group ◽  
Breathing Exercises ◽  
Sf 36 ◽  
Significant Difference ◽  
Before And After ◽  
Respiratory Exercises

Background/aims Workers engaged in vehicle spray painting are at a risk of developing respiratory problems because of the solvents in the spray paints. Changes in respiratory functions and functional capacities caused by spray painting can be improved with respiratory exercises. The aim of this study was to examine the effects of respiratory exercises on the respiratory functions, functional capacity and quality of life in vehicle spray painters. Methods A total of 70 volunteers with similar characteristics participated in the study. The groups were divided into two groups randomly (35 study group, 35 control group). Respiratory functions (value of forced expiratory volume percentage in 1 second [FEV1]), forced vital capacity percentage [FVC], FEV1/FVC percentage, peak expiratory flow percentage [PEF (%)] and maximum voluntary ventilation percentage [MVV (%)]), functional capacity (6-Minute Walk Test) and quality of life (Short Form Health Survey [SF-36]) were evaluated. The study group undertook supervised breathing exercises 3 days a week for 6 weeks. The same exercises were given to the control group as a home programme. Home programmes were followed up by telephone calls. Evaluations were performed again after 6 weeks. Results In the study group, FEV1 (%) increased more than in the control group (P<0.05). The increase in PEF (%) was similar in both groups (P>0.05). In the study group, FEV1/FVC (%) and MVV (%) were significantly different before and after the intervention (P<0.05), but there was no difference in the control group (P>0.05). There was a greater increase in the study group than in the control group (P<0.05). 6-Minute Walk Test distance (m) before and after the intervention in both groups were similar (P>0.05). Before and after the intervention, a significant difference was found in the vitality and the social function domains of the SF-36 in the study group. In the comparisons of groups, a significant difference was found in the study group in the role-emotional, social function and bodily pain domains of the SF-36 after the intervention (P<0.05). Conclusions Breathing exercises can be recommended for vehicle spray painters to avoid an increase in respiratory resistance and to improve their quality of life.

scholarly journals Improvement Legal Aspects and Completeness of Documentation using Electronic Nursing Record: A Report Study

2019 ◽  
Vol 1 (2) ◽  
pp. 32-39
Author(s):  
Rr.Tutik Sri Hariyati ◽  
Krisna Yetti Malawat ◽  
Retno Purwandari ◽  
Effy Afifah
Keyword(s):  
Legal Aspect ◽  
Legal Aspects ◽  
Control Group ◽  
Nursing Documentation ◽  
Study Approach ◽  
Before And After ◽  
Post Test ◽  
Nursing Activity ◽  
Quality Of Nursing

Background: Completeness of documentation as a legal aspect and proof a nursing activity. Nothing documentation means nothing activity.Objective: The Purpose of research to identify the legal aspect and completeness of nursing documentation after applying electronic nursing documentation. Methods: Report study approach and using pre and post-test with the control group. Thirty Four documentation collected using consecutive sampling on one-week observation before and after using electronic nursing information. The research compared the legal aspect and completeness of data conducted before and after the implementation of the new system.Results: The study showed improvement of the legal aspects increased by 50% (4,40 to 8,00) and completeness documentation by 10.39%  (43,00 to 49,00) after used of a system.   Conclusion: Nursing Electronic Documentation improved legal aspect, completeness nursing and enhance the quality of nursing care. Recommendation: Electronic nursing documentation can be done to support and increase the quality of nursing.  

scholarly journals The Unemployment of Today and Tomorrow in Romania

2014 ◽  
Vol 2 (1) ◽  
pp. 52
Author(s):  
Mictat Garlan
Keyword(s):  
Labor Migration ◽  
Business Environment ◽  
Political Regime ◽  
National Commission ◽  
Economic Policies ◽  
Active Population ◽  
Before And After ◽  
The One ◽  
State Enterprises

For any political regime the employment and unemployment of active population represents the most pressing social and economic obligation. in Romania, any comparative study before and after 1990, on 2 x 2 decades of different economic policies, can observe the damaging effects which they had forced privatization of state enterprises on the labor market, with over 1,000,000 declared unemployed in 1999, compared to zero unemployed in 1989. After this disaster, and after a short economic rehabilitation, it followed another crisis, with a further increase in unemployment of ANOFM, from 445,000 persons in 2009 to 626,960 persons in 2010 to 740,000 in 2011 of 674,000 in November 2012 , 512 333 persons in December 2013 to 724,000 persons in March 2014. These data indicate that in Romania the crisis is not over yet. in parallel to these developments there have been published the analyzes of the National Commission for Prognosis, but with some significant deviations in two directions. On the one hand, the calculations are made on the formula BIM records, and on the other hand, they are in the direction of a lower estimates. So, in the estimates of performed forecasts for the years 2014 -2017, with trend analysis and analysis of previous years, the total number of unemployed in 2011 was to be of 730 200 persons. in 2012 the total number of unemployed was to be of 701,200 persons, in 2013 of 726,000 persons, of 705,000 persons in 2014, of 690,000 in 2015 and of 685,000 in 2016. Without contesting the effort to accuracy of this Commission and the fact that any forecast includes a dose of risk too, there are obviously immeasurable variables that were not taken into account. We refer to the quality of business environment, revenues polarization, with decreasing trends in wages, to labor migration especially medium and high qualified. We refer to the existing difficulties in the allocation of development credits, to the corruption of officials from the local councils the excess of electoral concerns of governments, with the necessity of different approaches for each of them. With this supplement of fren factors we can say that on prospective 2 years, the registered unemployment from National Institute of Statistics, will not fall below 740.000 persons. To these things, it must be added the volume of more than twice unregistered persons, which means a total of approx. two million persons, this being the actual estimation of the non-employed population, to which has reached in Romania today.

Abstract 722: Treatment of Acute and Chronic Limb Ischemia with Intermedin (IMD) in Mouse Models

2015 ◽  
Vol 35 (suppl_1) ◽  
Author(s):  
Luyu Yao ◽  
Honglin Dong ◽  
Allen Gu ◽  
Xin Gu ◽  
Kai Yao ◽  
...  
Keyword(s):  
Femoral Artery ◽  
Blood Perfusion ◽  
Limb Ischemia ◽  
Control Group ◽  
Silk Suture ◽  
Hindlimb Ischemia ◽  
Occlusion Model ◽  
Before And After ◽  
Artery Disease ◽  
The One

Objectives: This experiment proposes a novel mouse model to simulate long-term chronic ischemia caused by peripheral artery disease (PAD) using a partial ligation method to narrow down the femoral artery lumen in C57Bl/6 mice. This model will be compared to the typical occlusion model while testing Intermedin (IMD) as a possible treatment for ischemia. Methods: Partial hindlimb ligation technique: we use a strand of 11-0 nylon sutures to pierce the middle of the artery and suture half of the artery shut at both the proximal and distal end of the femoral artery. The typical occlusion model: we use a 7-0 silk suture to completely ligate the distal and proximal femoral artery. Hindlimb blood flow was monitored daily by Laser Doppler perfusion monitor before and after the surgery. IMD was administered at 150 μg/kg, ip, immediately following ligation and twice daily afterwards for up to one week, while in the control group saline was injected instead of IMD. Gastrocnemius muscle samples were collected at day 3 and day 7 for histology and molecular biology study. Results: Ischemic/non-ischemic leg blood perfusion ratio in the partial ligation model is significantly higher than in the typical model. It is also significantly increased in IMD-treated groups in both models. Compared to the tissue in complete ligation models, it is apparent that partial ligation model tissue is less severely affected upon initial ligation but maintains ischemia over the one week testing period as would be expected. Compared to the untreated ischemia groups in acute and chronic hindlimb ischemia models, IMD-treated animals had less severe ischemic injuries. Conclusion: Our study indicates that our chronic hindlimb ischemia model was successful with expected less ischemia status than complete occlusion. The partial occlusion model presented here more closely mimics human PAD, where atherosclerotic plaque builds up slowly, resulting in a lower pressure difference between the proximal and distal artery preventing adequate shunting of the blood into collateral circulation. Moreover, our study suggests that IMD has promise as a therapeutic treatment in acute and chronic hindlimb ischemia models to prevent necrosis in muscle tissue following ischemic events.

scholarly journals Pengaruh Pemasangan Poster Anjuran Buang Sampah terhadap Pemanfaatan Tempat Sampah di Tempat Wisata

2019 ◽  
Vol 14 (2) ◽  
pp. 149
Author(s):  
Nining Prastiwi ◽  
Zahroh Shaluhiyah ◽  
Farid Agushybana
Keyword(s):  
Control Sample ◽  
Total Sample ◽  
Control Group ◽  
Tourist Destinations ◽  
Intervention Area ◽  
Before And After ◽  
Post Test ◽  
And Behavior ◽  
Vacation Period

Background: Cleanliness of tourist area is managers and visitors responsibilities to maintain the beauty of tourist destinations. Disposing of trash in its place becomes very important in maintaining the cleanliness of tourist sites. The role of health promotion media to improve awareness and behavior of tourist in maintaining cleanliness is necessary to be conducted. The purpose of this study was to analyze the effect of providing garbage disposal posters towards the utilising trash bin in tourist sites.Method: This study employs a quantitative method with a quasy experimental approach, non randomized control group pretest posttest design. It was carried out in four tourist sites which consist of two tourist sites as intervention area and the others as control. Sample of this study was consisted of 15 bins/each site which met the criteria of sanitation standards and selected purposively so that the total sample was 30 bins in the intervention and 30 bins in the control areas. The variables included the volume of waste in each trash bin, the quality of trash bin distributed and the number of visitors before and after intervention. Measurements were conducted for 14 days.Results: The volume of waste was increased significantly after providing posters in the intervention sites compared to controls’. Likewise, the quality of trash bin distributed at tourist sites was also increased significantly in the intervention areas compared to controls. The number of visitors at four destinations was increased significantly after intervention because post-test was conducted at long vacation period. That would directly effect to waste volume in the trash bin at 4 tourist destinations. This study recommends to managers to put interesting poster or other instagramable media to promote healthy behaviour related to the cleanliness and beauty at tourist areas.

scholarly journals Effects of a Rehabilitation Programme with a Nasal Inspiratory Restriction Device on Exercise Capacity and Quality of Life in COPD

2020 ◽  
Vol 17 (10) ◽  
pp. 3669 ◽  
Author(s):  
Aurelio Arnedillo ◽  
Jose L. Gonzalez-Montesinos ◽  
Jorge R. Fernandez-Santos ◽  
Carmen Vaz-Pardal ◽  
Carolina España-Domínguez ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Exercise Capacity ◽  
Rehabilitation Program ◽  
Inspiratory Muscle ◽  
Control Group ◽  
6Mwt Distance ◽  
Before And After ◽  
Inspiratory Muscle Strength

Objective: The objective was to assess the effects of a nasal restriction device for inspiratory muscle training, called Feelbreathe®, added to a rehabilitation program (RP) on exercise capacity, quality of life, dyspnea and inspiratory muscle strength in patients with stable COPD. Methods: Patients were randomized into three groups, one performed a supervised RP using the Feelbreathe® device (FB group), the second group developed the same RP with oronasal breathing without FB (ONB group) and the third was the control group (CG). We evaluated inspiratory muscle strength (PImax), dyspnea (mMRC), quality of life (CAT) and exercise capacity (6MWT) before and after 8-week of RP. Results: A total of 16 patients completed the study, seven in FB group, five in ONB group and four in the CG. After the RP, the FB group showed a significant increase in PImax (93.3 ± 19.1 vs. 123.0 ± 15.8 mmHg) and in the 6MWT distance (462.9 ± 71.8 m vs. 529.1 ± 50.1 m) and a decrease in the CAT score (9.7 ± 6.5 vs. 5.9 ± 6.0) and in the mMRC dyspnea score. FB provides greater improvement in PImax, dyspnea, quality of life and 6MWT than ONB. Conclusions: The Feelbreathe® device provides greater improvements in quality of life, dyspnea, exercise capacity and inspiratory muscle strength compared to patients that did not use it.

scholarly journals Perception of One’s Own Voice After Hearing-Aid Fitting for Naive Hearing-Aid Users and Hearing-Aid Refitting for Experienced Hearing-Aid Users

2020 ◽  
Vol 24 ◽  
pp. 233121652093246
Author(s):  
Johanna Hengen ◽  
Inger L. Hammarström ◽  
Stefan Stenfelt
Keyword(s):  
Hearing Impairment ◽  
Hearing Aids ◽  
Hearing Aid ◽  
Control Group ◽  
Voice Perception ◽  
Hearing Aid Fitting ◽  
Before And After ◽  
Vocal Intensity ◽  
First Time

Dissatisfaction with the sound of one’s own voice is common among hearing-aid users. Little is known regarding how hearing impairment and hearing aids separately affect own-voice perception. This study examined own-voice perception and associated issues before and after a hearing-aid fitting for new hearing-aid users and refitting for experienced users to investigate whether it was possible to differentiate between the effect of (unaided) hearing impairment and hearing aids. Further aims were to investigate whether First-Time and Experienced users as well as users with dome and mold inserts differed in the severity of own-voice problems. The study had a cohort design with three groups: First-Time hearing-aid users going from unaided to aided hearing ( n = 70), Experienced hearing-aid users replacing their old hearing aids ( n = 70), and an unaided control group ( n = 70). The control group was surveyed once and the hearing-aid users twice; once before hearing-aid fitting/refitting and once after. The results demonstrated that own-voice problems are common among both First-Time and Experienced hearing-aid users with either dome- or mold-type fittings, while people with near-normal hearing and not using hearing aids report few problems. Hearing aids increased ratings of own-voice problems among First-Time users, particularly those with mold inserts. The results suggest that altered auditory feedback through unaided hearing impairment or through hearing aids is likely both to change own-voice perception and complicate regulation of vocal intensity, but hearing aids are the primary reason for poor perceived sound quality of one’s own voice.

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